IL101162A - Pharmaceutical composition for oral administration comprising an indole derivative - Google Patents
Pharmaceutical composition for oral administration comprising an indole derivativeInfo
- Publication number
- IL101162A IL101162A IL101162A IL10116292A IL101162A IL 101162 A IL101162 A IL 101162A IL 101162 A IL101162 A IL 101162A IL 10116292 A IL10116292 A IL 10116292A IL 101162 A IL101162 A IL 101162A
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical composition
- oral administration
- indole derivative
- film
- solid dosage
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000002475 indoles Chemical class 0.000 title 1
- 239000007909 solid dosage form Substances 0.000 abstract 2
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- KQKPFRSPSRPDEB-UHFFFAOYSA-N sumatriptan Chemical compound CNS(=O)(=O)CC1=CC=C2NC=C(CCN(C)C)C2=C1 KQKPFRSPSRPDEB-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Waveguide Aerials (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Non-Reversible Transmitting Devices (AREA)
- Control Of Motors That Do Not Use Commutators (AREA)
- Medicines Containing Plant Substances (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919104890A GB9104890D0 (en) | 1991-03-08 | 1991-03-08 | Compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL101162A0 IL101162A0 (en) | 1992-11-15 |
| IL101162A true IL101162A (en) | 1997-11-20 |
Family
ID=42342461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL101162A IL101162A (en) | 1991-03-08 | 1992-03-06 | Pharmaceutical composition for oral administration comprising an indole derivative |
Country Status (29)
| Country | Link |
|---|---|
| US (4) | US5863559A (de) |
| EP (1) | EP0503440B1 (de) |
| JP (1) | JP2986546B2 (de) |
| KR (1) | KR100202042B1 (de) |
| AT (1) | ATE165973T1 (de) |
| AU (1) | AU663303B2 (de) |
| BE (1) | BE1005086A5 (de) |
| CA (1) | CA2105180C (de) |
| CH (1) | CH684242A5 (de) |
| CY (1) | CY2011A (de) |
| CZ (1) | CZ282352B6 (de) |
| DE (1) | DE69225421T2 (de) |
| DK (1) | DK0503440T3 (de) |
| ES (1) | ES2117015T3 (de) |
| FR (1) | FR2673538B1 (de) |
| GB (2) | GB9104890D0 (de) |
| GE (1) | GEP20012549B (de) |
| HK (1) | HK19395A (de) |
| IE (1) | IE920726A1 (de) |
| IL (1) | IL101162A (de) |
| IT (1) | IT1271495B (de) |
| MX (1) | MX9200992A (de) |
| NL (1) | NL9200423A (de) |
| NZ (1) | NZ241873A (de) |
| OA (1) | OA09812A (de) |
| RU (1) | RU2098093C1 (de) |
| SG (1) | SG169294G (de) |
| WO (1) | WO1992015295A1 (de) |
| ZA (1) | ZA921690B (de) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9104890D0 (en) * | 1991-03-08 | 1991-04-24 | Glaxo Group Ltd | Compositions |
| ES2106818T3 (es) * | 1991-10-30 | 1997-11-16 | Glaxo Group Ltd | Composicion multicapa que contiene antagonistas de histamina o secotina. |
| DE4314976C1 (de) * | 1993-05-06 | 1994-10-06 | Lohmann Therapie Syst Lts | Transdermale therapeutische Systeme zur Verabreichung von Wirkstoffen, Verfahren zu ihrer Herstellung und ihre Verwendung |
| US8022095B2 (en) * | 1996-08-16 | 2011-09-20 | Pozen, Inc. | Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs |
| US7189753B1 (en) | 1997-11-06 | 2007-03-13 | Cady Roger K | Preemptive prophylaxis of migraine |
| US6066092A (en) * | 1997-11-06 | 2000-05-23 | Cady; Roger K. | Preemptive prophylaxis of migraine device and method |
| GB9924717D0 (en) * | 1999-10-19 | 1999-12-22 | Glaxo Group Ltd | Diagnostic |
| AT500063A1 (de) | 1999-11-23 | 2005-10-15 | Sandoz Ag | Beschichtete tablettenkerne |
| WO2002026210A2 (en) * | 2000-09-29 | 2002-04-04 | Geneva Pharmaceuticals Inc. | Proton pump inhibitor formulation |
| US20030070584A1 (en) * | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing cellulose ethers |
| AU4061702A (en) * | 2001-05-15 | 2003-04-03 | Mcneil-Ppc, Inc. | Dip coating compositions containing starch or dextrin |
| US8329734B2 (en) * | 2009-07-27 | 2012-12-11 | Afgin Pharma Llc | Topical therapy for migraine |
| DK1435945T3 (da) * | 2001-06-05 | 2008-12-01 | Ronald Aung-Din | Topisk migræne terapi |
| US8309118B2 (en) * | 2001-09-28 | 2012-11-13 | Mcneil-Ppc, Inc. | Film forming compositions containing sucralose |
| GB0129117D0 (en) * | 2001-12-05 | 2002-01-23 | Glaxo Group Ltd | Pharmaceutical composition |
| US20040052843A1 (en) * | 2001-12-24 | 2004-03-18 | Lerner E. Itzhak | Controlled release dosage forms |
| US20030228363A1 (en) * | 2002-06-07 | 2003-12-11 | Patel Mahendra R. | Stabilized pharmaceutical compositons containing benzimidazole compounds |
| AU2003249478A1 (en) * | 2002-07-19 | 2004-02-09 | Ranbaxy Laboratories Limited | Taste masked sumatriptan tablets and processes for their preparation |
| US7429619B2 (en) * | 2002-08-02 | 2008-09-30 | Mcneil Consumer Healthcare | Polyacrylic film forming compositions |
| US20040068000A1 (en) * | 2002-10-02 | 2004-04-08 | Mintong Guo | Compression coated tablets |
| ES2380827T3 (es) * | 2002-12-26 | 2012-05-18 | Pozen, Inc. | Formas de dosificación con múltiples capas que contienen naproxeno y triptanes |
| US20080213363A1 (en) * | 2003-01-23 | 2008-09-04 | Singh Nikhilesh N | Methods and compositions for delivering 5-HT3 antagonists across the oral mucosa |
| WO2004076403A1 (en) * | 2003-02-24 | 2004-09-10 | Transform Pharmaceuticals, Inc. | Sumatriptan crystalline forms, pharmaceutical compositions and methods |
| KR20060015641A (ko) * | 2003-06-06 | 2006-02-17 | 글락소 그룹 리미티드 | 트립탄 및 nsaid를 포함하는 조성물 |
| US20070065463A1 (en) | 2003-06-20 | 2007-03-22 | Ronald Aung-Din | Topical therapy for the treatment of migranes, muscle sprains, muscle spasms, spasticity and related conditions |
| GB2407498B (en) * | 2003-10-30 | 2008-06-11 | Cipla Ltd | Oral formulations for 5-HT receptor agonists with reduced degradation of active ingredient |
| GB0400452D0 (en) * | 2004-01-09 | 2004-02-11 | Norton Healthcare Ltd | A pharmaceutical composition |
| GB0403628D0 (en) * | 2004-02-18 | 2004-03-24 | Arrow Group Ltd | Compression-coated tablets and the manufacture thereof |
| US8216610B2 (en) * | 2004-05-28 | 2012-07-10 | Imaginot Pty Ltd. | Oral paracetamol formulations |
| EP3216445A1 (de) * | 2004-05-28 | 2017-09-13 | Imaginot Pty Ltd. | Abgabesystem für eine orale therapeutische verbindung |
| US20060002989A1 (en) * | 2004-06-10 | 2006-01-05 | Ahmed Salah U | Formulations of sumatriptan for absorption across biological membranes, and methods of making and using the same |
| MY147767A (en) | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| KR20080012360A (ko) | 2005-05-20 | 2008-02-11 | 얀센 파마슈티카 엔.브이. | 설파미드 유도체의 제조 방법 |
| CA2629904C (en) * | 2005-11-28 | 2018-07-10 | Imaginot Pty Ltd. | Oral therapeutic compound delivery system |
| WO2007070504A2 (en) * | 2005-12-13 | 2007-06-21 | Morton Grove Pharmaceuticals, Inc. | Stable and palatable oral liquid sumatriptan compositions |
| US8492431B2 (en) | 2005-12-19 | 2013-07-23 | Janssen Pharmaceutica, N.V. | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity |
| US8497298B2 (en) | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
| US8716231B2 (en) | 2005-12-19 | 2014-05-06 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain |
| US8691867B2 (en) | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
| US8937096B2 (en) | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
| RU2313340C1 (ru) * | 2006-02-20 | 2007-12-27 | Дмитрий Владимирович Зимин | Лекарственное средство, обладающее противомигренозным действием, и способ его изготовления |
| EA200870556A1 (ru) | 2006-05-19 | 2009-06-30 | Янссен Фармацевтика Н.В. | Комбинированная терапия в лечении эпилепсии и родственных расстройств |
| SI2124556T1 (sl) | 2006-10-09 | 2015-01-30 | Charleston Laboratories, Inc. | Farmacevtske sestave |
| CA2666149A1 (en) * | 2006-10-19 | 2008-04-24 | Auspex Pharmaceuticals, Inc. | Substituted indoles |
| EP3090743A1 (de) | 2008-01-09 | 2016-11-09 | Charleston Laboratories, Inc. | Pharmazeutische zusammensetzungen |
| US20090252791A1 (en) * | 2008-04-02 | 2009-10-08 | Venkata Nookaraju Sreedharala | Pharmaceutical compositions comprising a triptan and a nonsteroidal anti-inflammatory drug |
| RU2424803C2 (ru) * | 2008-04-07 | 2011-07-27 | Учреждение Российской академии медицинских наук Научно-исследовательский институт фармакологии имени В.В. Закусова РАМН (НИИ фармакологии имени В.В.Закусова РАМН) | Фармацевтическая композиция с противомигреневым действием (варианты) |
| US8618157B2 (en) * | 2008-06-20 | 2013-12-31 | Alphapharm Pty. Ltd. | Pharmaceutical formulation |
| EA018567B1 (ru) | 2008-06-23 | 2013-08-30 | Янссен Фармацевтика Нв | Кристаллическая форма (2s)-(-)-n-(6-хлор-2,3-дигидробензо[1,4]диоксин-2-илметил)сульфамида |
| JP2011526889A (ja) * | 2008-06-30 | 2011-10-20 | アフギン ファーマ,エルエルシー | 局所局部的神経作用療法 |
| US8815939B2 (en) | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
| CA2767576C (en) | 2009-07-08 | 2020-03-10 | Charleston Laboratories Inc. | Pharmaceutical compositions comprising an antiemetic and an opioid analgesic |
| US11337962B2 (en) | 2009-09-25 | 2022-05-24 | Upsher-Smith Laboratories, Llc | Formulations comprising triptan compounds |
| DK2480197T3 (en) | 2009-09-25 | 2016-01-25 | Reddys Lab Ltd Dr | Compositions containing triptanforbindelser |
| HK1244715A1 (zh) | 2015-03-02 | 2018-08-17 | 阿福金制药有限责任公司 | 用大麻素的局部区域神经影响性疗法 |
| US10383816B2 (en) | 2015-03-02 | 2019-08-20 | Afgin Pharma, Llc | Topical regional neuro-affective therapy with cannabinoid combination products |
| CA3055170A1 (en) | 2016-03-04 | 2017-09-08 | Charleston Laboratories, Inc. | Pharmaceutical compositions |
| US20180049994A1 (en) | 2016-08-16 | 2018-02-22 | Afgin Pharma, Llc | Topical regional neuro-affective therapy with caryophyllene |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1170387B (it) * | 1982-06-07 | 1987-06-03 | Glaxo Group Ltd | Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono |
| GB8332437D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Chemical compounds |
| GB8419575D0 (en) * | 1984-08-01 | 1984-09-05 | Glaxo Group Ltd | Chemical compounds |
| GB2162522B (en) * | 1984-08-01 | 1988-02-24 | Glaxo Group Ltd | An indole derivative |
| GB8928208D0 (en) * | 1989-12-13 | 1990-02-14 | Glaxo Group Ltd | Medicaments |
| GB9104890D0 (en) * | 1991-03-08 | 1991-04-24 | Glaxo Group Ltd | Compositions |
-
1991
- 1991-03-08 GB GB919104890A patent/GB9104890D0/en active Pending
-
1992
- 1992-03-02 CZ CS931849A patent/CZ282352B6/cs not_active IP Right Cessation
- 1992-03-02 AU AU13264/92A patent/AU663303B2/en not_active Ceased
- 1992-03-02 CA CA002105180A patent/CA2105180C/en not_active Expired - Fee Related
- 1992-03-02 KR KR1019930702672A patent/KR100202042B1/ko not_active Expired - Fee Related
- 1992-03-02 JP JP4504967A patent/JP2986546B2/ja not_active Expired - Fee Related
- 1992-03-02 EP EP92103592A patent/EP0503440B1/de not_active Expired - Lifetime
- 1992-03-02 AT AT92103592T patent/ATE165973T1/de not_active IP Right Cessation
- 1992-03-02 US US08/381,422 patent/US5863559A/en not_active Expired - Fee Related
- 1992-03-02 WO PCT/EP1992/000460 patent/WO1992015295A1/en not_active Ceased
- 1992-03-02 DK DK92103592T patent/DK0503440T3/da active
- 1992-03-02 GE GEAP19922601A patent/GEP20012549B/en unknown
- 1992-03-02 ES ES92103592T patent/ES2117015T3/es not_active Expired - Lifetime
- 1992-03-02 RU RU9393057724A patent/RU2098093C1/ru not_active IP Right Cessation
- 1992-03-02 DE DE69225421T patent/DE69225421T2/de not_active Expired - Fee Related
- 1992-03-05 GB GB9204761A patent/GB2254784B/en not_active Expired - Fee Related
- 1992-03-06 FR FR9202709A patent/FR2673538B1/fr not_active Expired - Fee Related
- 1992-03-06 BE BE9200230A patent/BE1005086A5/fr not_active IP Right Cessation
- 1992-03-06 ZA ZA921690A patent/ZA921690B/xx unknown
- 1992-03-06 IE IE072692A patent/IE920726A1/en not_active IP Right Cessation
- 1992-03-06 NZ NZ241873A patent/NZ241873A/xx unknown
- 1992-03-06 IL IL101162A patent/IL101162A/xx unknown
- 1992-03-06 CH CH727/92A patent/CH684242A5/fr not_active IP Right Cessation
- 1992-03-06 MX MX9200992A patent/MX9200992A/es not_active IP Right Cessation
- 1992-03-06 NL NL9200423A patent/NL9200423A/nl active Search and Examination
- 1992-03-06 IT ITRM920155A patent/IT1271495B/it active IP Right Grant
-
1993
- 1993-08-19 OA OA60402A patent/OA09812A/en unknown
-
1994
- 1994-12-01 SG SG169294A patent/SG169294G/en unknown
-
1995
- 1995-02-09 HK HK19395A patent/HK19395A/xx not_active IP Right Cessation
-
1998
- 1998-02-20 CY CY201198A patent/CY2011A/en unknown
- 1998-07-24 US US09/121,530 patent/US6020001A/en not_active Expired - Fee Related
-
2000
- 2000-01-13 US US09/481,933 patent/US6368627B1/en not_active Expired - Fee Related
-
2002
- 2002-02-28 US US10/084,683 patent/US20020197318A1/en not_active Abandoned
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