IL101764A - Grf analogs and pharmaceutical compositions containing them - Google Patents

Grf analogs and pharmaceutical compositions containing them

Info

Publication number
IL101764A
IL101764A IL10176492A IL10176492A IL101764A IL 101764 A IL101764 A IL 101764A IL 10176492 A IL10176492 A IL 10176492A IL 10176492 A IL10176492 A IL 10176492A IL 101764 A IL101764 A IL 101764A
Authority
IL
Israel
Prior art keywords
ala
leu
arg
peptide
ser
Prior art date
Application number
IL10176492A
Other languages
English (en)
Other versions
IL101764A0 (en
Original Assignee
Salk Inst For Biological Studi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Inst For Biological Studi filed Critical Salk Inst For Biological Studi
Publication of IL101764A0 publication Critical patent/IL101764A0/xx
Publication of IL101764A publication Critical patent/IL101764A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)
  • Junction Field-Effect Transistors (AREA)
  • Revetment (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Control Of High-Frequency Heating Circuits (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Lighting Device Outwards From Vehicle And Optical Signal (AREA)
IL10176492A 1991-05-15 1992-05-01 Grf analogs and pharmaceutical compositions containing them IL101764A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/701,414 US5262519A (en) 1991-05-15 1991-05-15 GRF analogs XI

Publications (2)

Publication Number Publication Date
IL101764A0 IL101764A0 (en) 1992-12-30
IL101764A true IL101764A (en) 1996-07-23

Family

ID=24817283

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10176492A IL101764A (en) 1991-05-15 1992-05-01 Grf analogs and pharmaceutical compositions containing them

Country Status (13)

Country Link
US (1) US5262519A (de)
EP (1) EP0514210B1 (de)
JP (1) JPH06500575A (de)
KR (1) KR100236413B1 (de)
AT (1) ATE187741T1 (de)
AU (1) AU654195B2 (de)
CA (1) CA2086676A1 (de)
DE (1) DE69230418D1 (de)
FI (1) FI930152A0 (de)
IL (1) IL101764A (de)
NZ (1) NZ242610A (de)
WO (1) WO1992020710A1 (de)
ZA (1) ZA923281B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2082059A1 (en) * 1990-05-04 1991-11-05 David H. Coy Synthetic grf analogs
CA2158782C (en) * 1994-09-23 2010-01-12 Pierrette Gaudreau Marker for growth hormone-releasing factor receptors
EP0820296A4 (de) * 1995-04-14 1999-06-30 Univ Tulane Analoge von wachstumshormon-freisetzungsfaktor
KR20050071498A (ko) * 2002-09-18 2005-07-07 상트르 오스피딸리에 드 루니버시떼 드 몬트리알 성장 호르몬 방출 호르몬 유사체
DK2118123T3 (en) 2007-01-31 2016-01-25 Dana Farber Cancer Inst Inc Stabilized p53 peptides and uses thereof
US8592377B2 (en) 2007-03-28 2013-11-26 President And Fellows Of Harvard College Stitched polypeptides
US20090088380A1 (en) * 2007-07-12 2009-04-02 Pierrette Gaudreau Ghrh analogs and therapeutic uses thereof
WO2011153491A2 (en) 2010-06-03 2011-12-08 University Of Miami Agonists of growth hormone releasing hormone as effectors for survival and proliferation of pancreatic islets
ES2711526T3 (es) 2010-08-13 2019-05-06 Aileron Therapeutics Inc Macrociclos peptidomiméticos
KR20140027284A (ko) 2011-04-21 2014-03-06 쎄러테크놀로지스 인코포레이티드 성장 호르몬 방출 인자(grf) 유사체 및 이의 용도
TW201806968A (zh) 2011-10-18 2018-03-01 艾利倫治療公司 擬肽巨環化合物
US9079974B2 (en) 2011-12-21 2015-07-14 The University Of Miami GH-RH analogs with potent agonistic effects
BR112014020103A2 (pt) 2012-02-15 2018-10-09 Aileron Therapeutics, Inc. macrociclos peptidomiméticos
EP2819688A4 (de) 2012-02-15 2015-10-28 Aileron Therapeutics Inc Triazol- und thioethervernetzte peptidomimetische makrozyklen
WO2014071241A1 (en) 2012-11-01 2014-05-08 Aileron Therapeutics, Inc. Disubstituted amino acids and methods of preparation and use thereof
US9855312B2 (en) * 2012-12-21 2018-01-02 University Of Miami GHRH agonists for the treatment of ischemic disorders
WO2014100816A2 (en) 2012-12-21 2014-06-26 University Of Miami Ghrh agonists for islet cell transplantation and function and the treatment of diabetes
EP3197478A4 (de) 2014-09-24 2018-05-30 Aileron Therapeutics, Inc. Peptidomimetische makrozyklen und verwendungen davon
WO2016154058A1 (en) 2015-03-20 2016-09-29 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649131A (en) * 1984-09-24 1987-03-10 Hoffmann-La Roche Inc. Growth hormone releasing factor analogs
US4689318A (en) * 1985-08-29 1987-08-25 The Salk Institute For Biological Studies GRF analogs
US4746772A (en) * 1986-09-23 1988-05-24 Fisher Controls International, Inc. Adjustable position indicating apparatus
US4843064A (en) * 1987-01-13 1989-06-27 The Salk Institute For Biological Studies GRF analogs V
US5002931A (en) * 1987-05-22 1991-03-26 The Salk Institute For Biological Studies GRF analogs VII
US5098995A (en) * 1987-05-22 1992-03-24 The Salk Institute For Biological Studies GRF Analogs VIIA
US5043322A (en) * 1988-07-22 1991-08-27 The Salk Institute For Biological Studies Cyclic GRF analogs
CA2082059A1 (en) * 1990-05-04 1991-11-05 David H. Coy Synthetic grf analogs

Also Published As

Publication number Publication date
EP0514210B1 (de) 1999-12-15
US5262519A (en) 1993-11-16
JPH06500575A (ja) 1994-01-20
ATE187741T1 (de) 2000-01-15
EP0514210A3 (en) 1993-04-28
IL101764A0 (en) 1992-12-30
DE69230418D1 (de) 2000-01-20
WO1992020710A1 (en) 1992-11-26
AU1996392A (en) 1992-12-30
KR100236413B1 (ko) 1999-12-15
FI930152A7 (fi) 1993-01-14
EP0514210A2 (de) 1992-11-19
FI930152L (fi) 1993-01-14
KR930701483A (ko) 1993-06-11
AU654195B2 (en) 1994-10-27
ZA923281B (en) 1993-01-27
FI930152A0 (fi) 1993-01-14
NZ242610A (en) 1993-11-25
CA2086676A1 (en) 1992-11-16

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees