IL101829A - Essentially pure human parathyroid hormone its preparation and pharmaceutical compositions containing it - Google Patents

Essentially pure human parathyroid hormone its preparation and pharmaceutical compositions containing it

Info

Publication number
IL101829A
IL101829A IL10182992A IL10182992A IL101829A IL 101829 A IL101829 A IL 101829A IL 10182992 A IL10182992 A IL 10182992A IL 10182992 A IL10182992 A IL 10182992A IL 101829 A IL101829 A IL 101829A
Authority
IL
Israel
Prior art keywords
pth
parathyroid hormone
essentially pure
human parathyroid
pure human
Prior art date
Application number
IL10182992A
Other languages
English (en)
Other versions
IL101829A0 (en
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24840399&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL101829(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astra Ab filed Critical Astra Ab
Priority to IL11984092A priority Critical patent/IL119840A/xx
Publication of IL101829A0 publication Critical patent/IL101829A0/xx
Priority to IL11984096A priority patent/IL119840A0/xx
Publication of IL101829A publication Critical patent/IL101829A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/635Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL10182992A 1991-05-23 1992-05-11 Essentially pure human parathyroid hormone its preparation and pharmaceutical compositions containing it IL101829A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL11984092A IL119840A (en) 1991-05-23 1992-05-11 Method for purifying human parathyroid hormone
IL11984096A IL119840A0 (en) 1991-05-23 1996-12-16 A method for purifying human parathyroid hormone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/707,114 US5208041A (en) 1991-05-23 1991-05-23 Essentially pure human parathyroid hormone

Publications (2)

Publication Number Publication Date
IL101829A0 IL101829A0 (en) 1992-12-30
IL101829A true IL101829A (en) 1999-12-31

Family

ID=24840399

Family Applications (3)

Application Number Title Priority Date Filing Date
IL10182992A IL101829A (en) 1991-05-23 1992-05-11 Essentially pure human parathyroid hormone its preparation and pharmaceutical compositions containing it
IL11984092A IL119840A (en) 1991-05-23 1992-05-11 Method for purifying human parathyroid hormone
IL11984096A IL119840A0 (en) 1991-05-23 1996-12-16 A method for purifying human parathyroid hormone

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL11984092A IL119840A (en) 1991-05-23 1992-05-11 Method for purifying human parathyroid hormone
IL11984096A IL119840A0 (en) 1991-05-23 1996-12-16 A method for purifying human parathyroid hormone

Country Status (16)

Country Link
US (1) US5208041A (de)
EP (1) EP0515228B1 (de)
JP (1) JP2563726B2 (de)
KR (1) KR970007755B1 (de)
AT (1) ATE164394T1 (de)
CA (1) CA2068438C (de)
DE (1) DE69224858T2 (de)
DK (1) DK0515228T3 (de)
ES (1) ES2115642T3 (de)
FI (1) FI106802B (de)
HK (1) HK1004340A1 (de)
IE (1) IE921672A1 (de)
IL (3) IL101829A (de)
NO (2) NO304190B1 (de)
NZ (1) NZ242855A (de)
ZA (1) ZA923735B (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5420242A (en) * 1986-10-22 1995-05-30 Kaare M. Gautvik Production of human parathyroid hormone from microorganisms
USRE37919E1 (en) 1989-05-12 2002-12-03 The General Hospital Corporation Recombinant DNA method for production of parathyroid hormone
WO1995011697A1 (en) * 1993-10-27 1995-05-04 Chugai Seiyaku Kabushiki Kaisha Cure accelerator in chondroplasty
US5763416A (en) 1994-02-18 1998-06-09 The Regent Of The University Of Michigan Gene transfer into bone cells and tissues
US5962427A (en) 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
US20020193338A1 (en) * 1994-02-18 2002-12-19 Goldstein Steven A. In vivo gene transfer methods for wound healing
US5942496A (en) 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
US6074840A (en) 1994-02-18 2000-06-13 The Regents Of The University Of Michigan Recombinant production of latent TGF-beta binding protein-3 (LTBP-3)
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
ES2320603T3 (es) 1997-07-30 2009-05-25 Emory University Sistemas de expresion, vectores, adn, proteinas de mineralizacion osea novedosos.
US7923250B2 (en) 1997-07-30 2011-04-12 Warsaw Orthopedic, Inc. Methods of expressing LIM mineralization protein in non-osseous cells
US6770623B1 (en) * 1997-12-09 2004-08-03 Eli Lilly And Company Stabilized teriparatide solutions
DZ2873A1 (fr) 1998-08-19 2003-12-15 Lilly Co Eli Procédé pour augmenter la dureté et la rigidité osseuse.
JP4486256B2 (ja) * 1998-10-22 2010-06-23 ザ・ジェネラル・ホスピタル・コーポレイション 副甲状腺ホルモン(PTH)および副甲状腺ホルモン関連ペプチド(PTHrP)の生物活性ペプチドおよびペプチド誘導体
AU4217299A (en) 1998-11-30 2000-06-19 General Hospital Corporation, The Pth1r and pth3r receptors, methods and uses thereof
US6689566B1 (en) 1999-01-14 2004-02-10 Scantibodies Laboratory, Inc. Methods, kits, and antibodies for detecting parathyroid hormone
US7820393B2 (en) * 1999-01-14 2010-10-26 Scantibodies Laboratory, Inc. Methods, kits and antibodies for detecting parathyroid hormone
US20080108086A1 (en) * 1999-06-02 2008-05-08 Cantor Thomas L Parathyroid hormone antagonists and uses thereof
WO2004028444A2 (en) * 1999-06-02 2004-04-08 Scantibodies Laboratory, Inc. Parathyroid hormone antagonists and uses thereof
WO2001023521A2 (en) * 1999-09-29 2001-04-05 The General Hospital Corporation Polypeptide derivatives of parathyroid hormone (pth)
NZ523457A (en) * 2000-06-30 2004-11-26 Daiichi Suntory Pharma Co Composition for stimulating bone formation comprising hPTH in which the acetic acid component is low enough for administration to the nasal mucosa
US6387711B1 (en) * 2000-08-11 2002-05-14 Quest Diagnostics Investments Incorporated Liquid intact parathyroid hormone (PTH) standards
US6905886B2 (en) * 2000-08-11 2005-06-14 Quest Diagnostics Investments Incorporated Preservative solutions
AU2002339843B2 (en) * 2001-07-23 2007-12-06 The General Hospital Corporation Conformationally constrained parathyroid hormone (PTH) analogs
US20040067526A1 (en) * 2002-10-03 2004-04-08 Cantor Thomas L. Methods for diagnosing and guiding treatment of bone turnover disease
US7795220B2 (en) * 2003-03-19 2010-09-14 The General Hospital Corporation Conformationally constrained parathyroid hormones with alpha-helix stabilizers
KR100540659B1 (ko) * 2003-07-02 2006-01-10 삼성전자주식회사 이미지 확대 인쇄 방법과 장치 및 컴퓨터 프로그램을저장하는 컴퓨터로 읽을 수 있는 기록 매체
JP4871128B2 (ja) 2003-07-17 2012-02-08 ザ ジェネラル ホスピタル コーポレイション 高次構造的に制約された副甲状腺ホルモン(pth)アナログ
US7556821B2 (en) 2004-05-13 2009-07-07 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
US7541140B2 (en) * 2004-06-03 2009-06-02 Scantibodies Laboratory, Inc. Assessing risk for kidney stones using parathyroid hormone agonist and antagonist
CA2628945A1 (en) * 2005-11-10 2007-05-24 Board Of Control Of Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
WO2008019062A2 (en) * 2006-08-04 2008-02-14 The General Hospital Corporation Polypeptide derivatives of parathyroid hormone (pth)
CN104072606B (zh) * 2007-08-01 2017-09-22 总医院有限公司 利用g蛋白偶联受体和相关组合物的筛选方法
US8298789B2 (en) * 2007-08-09 2012-10-30 Usv Limited Orthogonal process for purification of recombinant human parathyroid hormone (rhPTH) (1-34)
CN102471368A (zh) * 2009-08-11 2012-05-23 拜康有限公司 色谱方法及其纯化的化合物
BR112012013725A2 (pt) 2009-12-07 2017-01-10 Univ Michigan Tech paratormônio de urso preto e métodos de usar o paratormônio de uso preto.
MX358161B (es) 2010-05-13 2018-08-06 The General Hospital Corp Star Analogos de hormona paratiroidea y usos para los mismos.
KR20150116467A (ko) 2011-06-07 2015-10-15 아사히 가세이 파마 가부시키가이샤 고순도 pth 함유 동결 건조 제제 및 그의 제조 방법
CN102993293B (zh) * 2012-12-05 2014-05-07 深圳翰宇药业股份有限公司 一种特立帕肽醋酸盐的纯化方法
LU100168B1 (en) 2017-04-12 2018-10-15 Michael Pazianas Prevention of Bone and Mineral Disorders by Restoring Calcium and Phosphate Homeostasis in Patients Suffering from Chronic Kidney Disease
EP4110370A4 (de) 2020-03-30 2023-06-07 Sichuan Luzhou Buchang Bio-Pharmaceutical Co., Ltd. Formulierungen des humanen parathyroidhormons (pth) und verfahren zur herstellung davon

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886132A (en) * 1972-12-21 1975-05-27 Us Health Human parathyroid hormone
US5223407A (en) * 1988-08-31 1993-06-29 Allelix Inc. Excretion of heterologous proteins from e. coli
AU6448990A (en) * 1989-09-29 1991-04-28 Her Majesty in Right of Canada, as represented by National Research Council Canada Synthesis of mature human parathyroid hormone

Also Published As

Publication number Publication date
JPH0687897A (ja) 1994-03-29
US5208041A (en) 1993-05-04
ZA923735B (en) 1993-01-27
FI922356L (fi) 1992-11-24
NO922000L (no) 1992-11-24
IL119840A (en) 2005-08-31
DK0515228T3 (da) 1998-09-28
IL119840A0 (en) 1997-03-18
ES2115642T3 (es) 1998-07-01
DE69224858D1 (de) 1998-04-30
NO2006013I1 (no) 2006-11-06
ATE164394T1 (de) 1998-04-15
JP2563726B2 (ja) 1996-12-18
NZ242855A (en) 1994-04-27
KR970007755B1 (en) 1997-05-16
IE921672A1 (en) 1992-12-02
DE69224858T2 (de) 1998-07-23
CA2068438A1 (en) 1992-11-24
FI106802B (fi) 2001-04-12
EP0515228B1 (de) 1998-03-25
NO2006013I2 (no) 2009-12-07
HK1004340A1 (en) 1998-11-20
CA2068438C (en) 1996-11-12
IL101829A0 (en) 1992-12-30
NO304190B1 (no) 1998-11-09
NO922000D0 (no) 1992-05-21
AU1604992A (en) 1993-03-11
EP0515228A3 (de) 1994-05-04
AU639856B2 (en) 1993-08-05
EP0515228A2 (de) 1992-11-25
FI922356A0 (fi) 1992-05-22

Similar Documents

Publication Publication Date Title
EP0515228B1 (de) Essentiell reines menschliches Parathyroidhormon
HK1004340B (en) Essentially pure human parathyroid hormone
Kroef et al. Production scale purification of biosynthetic human insulin by reversed-phase high-performance liquid chromatography
DE69130790T2 (de) Parathyroidhormon-Derivate
DE69632224T2 (de) Reduzierung von Gelation von Fettsäureacylierten Proteinen unter Nutzung von Zitratpuffer
US4785079A (en) Isolation of fibroblast growth factor
US4740587A (en) Inhibin and method of purifying same
JP3285862B2 (ja) 活性依存性神経栄養因子
EP0228452B1 (de) Proteinreinigung
US5290920A (en) Method of purifying human epidermal growth factor
DE68909254T2 (de) Heparinbindende Gehirnmitogene.
US4533494A (en) Process for purifying secretin
Stoffel et al. Analysis of the primary structure of the strongly hydrophobic brain myelin proteolipid apoprotein (lipophilin). Isolation and amino acid sequence determination of proteolytic fragments
CN116429950B (zh) 多肽pd-dp-005的有关物质分析方法
CA2113868A1 (en) Ultra-pure human interleukin-6
IE83494B1 (en) Essentially pure human parathyroid hormone
Welinder et al. Separation, isolation and characterization of the four monoiodinated insulin tracers using reversed-phase high-performance liquid chromatography
Yamamoto et al. Identification and purification of apolipoprotein C-III from the serum of cows
Zhang et al. Analysis and determination of biological activity of short-chain peptides from porcine brain hydrolysate
Welinder et al. Binding affinity of monoiodinated insulin tracers isolated after reversed-phase high-performance liquid chromatography
Kosciarz et al. Fractionation at pilot‐plant scale of an haemoglobin hydrolysate by strong anionic exchange chromatography Application to the preparation of an amphiphilic peptide
Giard-Pasquier et al. Purification of canine prolactin and growth hormone by fast protein liquid chromatography
Chang et al. Rapid purification of arrowhead proteinase inhibitors by high performance hydrophobic interaction chromatography on a PEG bonded phase column
Dimov et al. Experimental model for optimization of hydrophobic interaction: chromatographic purification of glucagon
DE19513784A1 (de) Hochreines Urodilatin und Verfahren zu seiner Herstellung

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired