IL102409A - Mono and bis alkylaminoanthracyclines their preparation and pharmaceutical compositions containing them - Google Patents

Mono and bis alkylaminoanthracyclines their preparation and pharmaceutical compositions containing them

Info

Publication number
IL102409A
IL102409A IL10240992A IL10240992A IL102409A IL 102409 A IL102409 A IL 102409A IL 10240992 A IL10240992 A IL 10240992A IL 10240992 A IL10240992 A IL 10240992A IL 102409 A IL102409 A IL 102409A
Authority
IL
Israel
Prior art keywords
formula
group
bis
daunorubicin
process according
Prior art date
Application number
IL10240992A
Other languages
English (en)
Other versions
IL102409A0 (en
Inventor
Alberto Bargiotti
Michele Caruso
Daniela Faiardi
Antonino Suarato
Nicola Mongelli
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of IL102409A0 publication Critical patent/IL102409A0/xx
Publication of IL102409A publication Critical patent/IL102409A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL10240992A 1991-07-05 1992-07-03 Mono and bis alkylaminoanthracyclines their preparation and pharmaceutical compositions containing them IL102409A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919114549A GB9114549D0 (en) 1991-07-05 1991-07-05 Mono and bis alkylamino-anthracyclines

Publications (2)

Publication Number Publication Date
IL102409A0 IL102409A0 (en) 1993-01-14
IL102409A true IL102409A (en) 1995-12-08

Family

ID=10697877

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10240992A IL102409A (en) 1991-07-05 1992-07-03 Mono and bis alkylaminoanthracyclines their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (1) US5496808A (cs)
EP (1) EP0521458B1 (cs)
JP (1) JP3153552B2 (cs)
KR (1) KR100235365B1 (cs)
CN (1) CN1031878C (cs)
AT (1) ATE134376T1 (cs)
AU (1) AU661012B2 (cs)
CA (1) CA2112818C (cs)
CZ (1) CZ2494A3 (cs)
DE (1) DE69208400T2 (cs)
FI (1) FI106204B (cs)
GB (1) GB9114549D0 (cs)
GR (1) GR3019429T3 (cs)
HU (1) HU218913B (cs)
IE (1) IE76921B1 (cs)
IL (1) IL102409A (cs)
MX (1) MX9203928A (cs)
NO (1) NO300099B1 (cs)
NZ (1) NZ243450A (cs)
RU (1) RU2118328C1 (cs)
TW (1) TW201753B (cs)
WO (1) WO1993001201A1 (cs)
ZA (1) ZA924971B (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9325420D0 (en) * 1993-12-13 1994-02-16 Erba Carlo Spa 4'-o-sulfonyl-anthracycline derivatives
GB9325417D0 (en) * 1993-12-13 1994-02-16 Erba Carlo Spa 3'- aziridino-anthracycline derivatives
WO1996008265A1 (en) * 1994-09-12 1996-03-21 The Trustees Of The University Of Pennsylvania Corticotropin release inhibiting factor and methods of using same
ATE176242T1 (de) * 1995-10-16 1999-02-15 Kyowa Hakko Kogyo Kk Uck14-verbindungen
DE19548474A1 (de) * 1995-12-22 1997-06-26 Wacker Chemie Gmbh Aliphatisch ungesättigte Reste aufweisende Organopolysiloxane, deren Herstellung und deren Verwendung in vernetzbaren Massen
GB9613433D0 (en) * 1996-06-26 1996-08-28 Pharmacia Spa Fluoro labelled anthracyclinone and anthracycline derivatives
AU6150498A (en) * 1997-02-07 1998-08-26 Wistar Institute, The Methods and compositions for the inhibition of interleukin-12 production
GB9806324D0 (en) * 1998-03-24 1998-05-20 Pharmacia & Upjohn Spa Antitumour synergetic composition
GB9904387D0 (en) * 1999-02-25 1999-04-21 Pharmacia & Upjohn Spa Antitumour synergistic composition
GB9904386D0 (en) 1999-02-25 1999-04-21 Pharmacia & Upjohn Spa Antitumour synergistic composition
EP4474386A1 (en) * 2023-06-07 2024-12-11 Academisch Ziekenhuis Leiden h.o.d.n. LUMC Anthracyclines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU570439B2 (en) * 1983-03-28 1988-03-17 Compression Labs, Inc. A combined intraframe and interframe transform coding system
US4591637A (en) * 1985-01-17 1986-05-27 Sri International Open chain-morpholino adriamycins
FR2591599B1 (fr) * 1985-12-17 1988-08-05 Hoechst Lab Nouvelles anthracyclines et medicaments les contenant
DE3842836A1 (de) * 1988-12-20 1990-06-21 Behringwerke Ag Rhodomycine mit einer modifizierten kohlenhydrat-einheit

Also Published As

Publication number Publication date
FI940011A7 (fi) 1994-01-03
HK1006460A1 (en) 1999-02-26
KR100235365B1 (ko) 1999-12-15
EP0521458B1 (en) 1996-02-21
IE922177A1 (en) 1993-01-13
AU2229492A (en) 1993-02-11
NO940026D0 (no) 1994-01-04
CA2112818A1 (en) 1993-01-21
CA2112818C (en) 2003-02-04
IE76921B1 (en) 1997-11-05
CN1031878C (zh) 1996-05-29
WO1993001201A1 (en) 1993-01-21
GB9114549D0 (en) 1991-08-21
TW201753B (cs) 1993-03-11
NO940026L (no) 1994-02-16
HU218913B (hu) 2000-12-28
JP3153552B2 (ja) 2001-04-09
NZ243450A (en) 1993-11-25
HU9400022D0 (en) 1994-05-30
AU661012B2 (en) 1995-07-13
US5496808A (en) 1996-03-05
JPH06508841A (ja) 1994-10-06
DE69208400D1 (de) 1996-03-28
ATE134376T1 (de) 1996-03-15
CN1069981A (zh) 1993-03-17
RU2118328C1 (ru) 1998-08-27
EP0521458A1 (en) 1993-01-07
MX9203928A (es) 1993-04-01
FI940011A0 (fi) 1994-01-03
CZ2494A3 (en) 1994-07-13
GR3019429T3 (en) 1996-06-30
FI106204B (fi) 2000-12-15
HUT70480A (en) 1995-10-30
DE69208400T2 (de) 1996-06-27
IL102409A0 (en) 1993-01-14
ZA924971B (en) 1993-03-31
NO300099B1 (no) 1997-04-07

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Legal Events

Date Code Title Description
FF Patent granted
HC Change of name of proprietor(s)
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees