IL105697A - Modification of the surface area of polysiloxane products and bedding coated by a wet chemical method - Google Patents

Modification of the surface area of polysiloxane products and bedding coated by a wet chemical method

Info

Publication number: IL105697A
Authority: IL; Israel
Prior art keywords: product; coating; solution; article; contacting
Prior art date: 1992-05-16

Application number

IL10569793A

Other languages

English (en)

Hebrew (he)

Other versions

IL105697A0 (en

Original Assignee

Gen Electric

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-05-16

Filing date

1993-05-13

Publication date

1998-12-06

1993-05-13 Application filed by Gen Electric filed Critical Gen Electric

1993-09-22 Publication of IL105697A0 publication Critical patent/IL105697A0/xx

1998-12-06 Publication of IL105697A publication Critical patent/IL105697A/en

Links

229920001296 polysiloxane Polymers 0.000 title claims abstract description 55
238000000034 method Methods 0.000 title claims abstract description 35
239000000758 substrate Substances 0.000 title claims abstract description 18
238000012986 modification Methods 0.000 title abstract description 12
-1 polysiloxane Polymers 0.000 title abstract description 12
239000000126 substance Substances 0.000 title abstract description 8
150000002500 ions Chemical class 0.000 claims abstract description 22
229910000000 metal hydroxide Inorganic materials 0.000 claims abstract description 22
150000004692 metal hydroxides Chemical class 0.000 claims abstract description 22
102000004169 proteins and genes Human genes 0.000 claims abstract description 9
108090000623 proteins and genes Proteins 0.000 claims abstract description 9
239000000243 solution Substances 0.000 claims description 93
239000000725 suspension Substances 0.000 claims description 21
238000000576 coating method Methods 0.000 claims description 20
238000005406 washing Methods 0.000 claims description 18
239000011248 coating agent Substances 0.000 claims description 16
239000000975 dye Substances 0.000 claims description 16
239000002245 particle Substances 0.000 claims description 9
235000018102 proteins Nutrition 0.000 claims description 8
108010038807 Oligopeptides Proteins 0.000 claims description 7
102000015636 Oligopeptides Human genes 0.000 claims description 7
239000003814 drug Substances 0.000 claims description 6
108090000765 processed proteins & peptides Proteins 0.000 claims description 6
102000004196 processed proteins & peptides Human genes 0.000 claims description 6
235000001014 amino acid Nutrition 0.000 claims description 5
150000001413 amino acids Chemical class 0.000 claims description 5
239000003054 catalyst Substances 0.000 claims description 5
238000004113 cell culture Methods 0.000 claims description 5
229910019142 PO4 Inorganic materials 0.000 claims description 4
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims description 4
QGZKDVFQNNGYKY-UHFFFAOYSA-O ammonium group Chemical group [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims description 4
150000007942 carboxylates Chemical class 0.000 claims description 4
239000004020 conductor Substances 0.000 claims description 4
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 4
239000010452 phosphate Substances 0.000 claims description 4
229920005862 polyol Polymers 0.000 claims description 4
150000003077 polyols Chemical class 0.000 claims description 4
239000007790 solid phase Substances 0.000 claims description 4
BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 claims description 4
239000008399 tap water Substances 0.000 claims description 4
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 3
239000002519 antifouling agent Substances 0.000 claims description 3
210000001124 body fluid Anatomy 0.000 claims description 3
239000010839 body fluid Substances 0.000 claims description 3
230000005672 electromagnetic field Effects 0.000 claims description 3
239000012266 salt solution Substances 0.000 claims description 3
239000013535 sea water Substances 0.000 claims description 3
102000003886 Glycoproteins Human genes 0.000 claims description 2
108090000288 Glycoproteins Proteins 0.000 claims description 2
108010028921 Lipopeptides Proteins 0.000 claims description 2
102000004895 Lipoproteins Human genes 0.000 claims description 2
108090001030 Lipoproteins Proteins 0.000 claims description 2
239000002861 polymer material Substances 0.000 claims description 2
235000020679 tap water Nutrition 0.000 claims description 2
150000001768 cations Chemical class 0.000 abstract description 9
230000004048 modification Effects 0.000 abstract description 5
150000001450 anions Chemical class 0.000 abstract description 3
229910021645 metal ion Inorganic materials 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 49
KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical class [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 48
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 27
239000000463 material Substances 0.000 description 18
235000011118 potassium hydroxide Nutrition 0.000 description 18
229920002379 silicone rubber Polymers 0.000 description 17
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 15
239000004945 silicone rubber Substances 0.000 description 14
239000008367 deionised water Substances 0.000 description 13
229910021641 deionized water Inorganic materials 0.000 description 13
235000011121 sodium hydroxide Nutrition 0.000 description 12
KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 9
210000004369 blood Anatomy 0.000 description 8
239000008280 blood Substances 0.000 description 8
239000000203 mixture Substances 0.000 description 8
239000003463 adsorbent Substances 0.000 description 7
229920000260 silastic Polymers 0.000 description 7
238000012360 testing method Methods 0.000 description 7
150000001875 compounds Chemical class 0.000 description 6
229920001971 elastomer Polymers 0.000 description 6
239000007943 implant Substances 0.000 description 6
239000002904 solvent Substances 0.000 description 5
OTXHZHQQWQTQMW-UHFFFAOYSA-N (diaminomethylideneamino)azanium;hydrogen carbonate Chemical compound OC([O-])=O.N[NH2+]C(N)=N OTXHZHQQWQTQMW-UHFFFAOYSA-N 0.000 description 4
BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 4
150000005325 alkali earth metal hydroxides Chemical class 0.000 description 4
150000008044 alkali metal hydroxides Chemical class 0.000 description 4
150000001720 carbohydrates Chemical class 0.000 description 4
150000001793 charged compounds Chemical class 0.000 description 4
239000000806 elastomer Substances 0.000 description 4
239000011888 foil Substances 0.000 description 4
230000002209 hydrophobic effect Effects 0.000 description 4
230000028327 secretion Effects 0.000 description 4
230000002792 vascular Effects 0.000 description 4
239000004475 Arginine Substances 0.000 description 3
102000016938 Catalase Human genes 0.000 description 3
108010053835 Catalase Proteins 0.000 description 3
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
WMFOQBRAJBCJND-UHFFFAOYSA-M Lithium hydroxide Chemical compound [Li+].[OH-] WMFOQBRAJBCJND-UHFFFAOYSA-M 0.000 description 3
ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 3
125000002091 cationic group Chemical group 0.000 description 3
210000004027 cell Anatomy 0.000 description 3
210000000038 chest Anatomy 0.000 description 3
238000009413 insulation Methods 0.000 description 3
239000007788 liquid Substances 0.000 description 3
239000012528 membrane Substances 0.000 description 3
150000002482 oligosaccharides Chemical class 0.000 description 3
INCIMLINXXICKS-UHFFFAOYSA-M pyronin Y Chemical compound [Cl-].C1=CC(=[N+](C)C)C=C2OC3=CC(N(C)C)=CC=C3C=C21 INCIMLINXXICKS-UHFFFAOYSA-M 0.000 description 3
238000003127 radioimmunoassay Methods 0.000 description 3
239000000523 sample Substances 0.000 description 3
229910052709 silver Inorganic materials 0.000 description 3
239000004332 silver Substances 0.000 description 3
239000011734 sodium Substances 0.000 description 3
229910052708 sodium Inorganic materials 0.000 description 3
230000008961 swelling Effects 0.000 description 3
238000002965 ELISA Methods 0.000 description 2
102000004190 Enzymes Human genes 0.000 description 2
108090000790 Enzymes Proteins 0.000 description 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 description 2
150000001298 alcohols Chemical class 0.000 description 2
125000000129 anionic group Chemical group 0.000 description 2
239000007864 aqueous solution Substances 0.000 description 2
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
RQPZNWPYLFFXCP-UHFFFAOYSA-L barium dihydroxide Chemical compound [OH-].[OH-].[Ba+2] RQPZNWPYLFFXCP-UHFFFAOYSA-L 0.000 description 2
229910001863 barium hydroxide Inorganic materials 0.000 description 2
TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 2
230000001419 dependent effect Effects 0.000 description 2
239000000428 dust Substances 0.000 description 2
210000002889 endothelial cell Anatomy 0.000 description 2
239000012530 fluid Substances 0.000 description 2
GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 description 2
150000004676 glycans Chemical class 0.000 description 2
PJJJBBJSCAKJQF-UHFFFAOYSA-N guanidinium chloride Chemical compound [Cl-].NC(N)=[NH2+] PJJJBBJSCAKJQF-UHFFFAOYSA-N 0.000 description 2
230000003100 immobilizing effect Effects 0.000 description 2
238000004255 ion exchange chromatography Methods 0.000 description 2
GBMDVOWEEQVZKZ-UHFFFAOYSA-N methanol;hydrate Chemical compound O.OC GBMDVOWEEQVZKZ-UHFFFAOYSA-N 0.000 description 2
210000003097 mucus Anatomy 0.000 description 2
229920001542 oligosaccharide Polymers 0.000 description 2
239000001301 oxygen Substances 0.000 description 2
229910052760 oxygen Inorganic materials 0.000 description 2
BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
229920001282 polysaccharide Polymers 0.000 description 2
239000005017 polysaccharide Substances 0.000 description 2
239000012763 reinforcing filler Substances 0.000 description 2
CPRMKOQKXYSDML-UHFFFAOYSA-M rubidium hydroxide Chemical compound [OH-].[Rb+] CPRMKOQKXYSDML-UHFFFAOYSA-M 0.000 description 2
238000001004 secondary ion mass spectrometry Methods 0.000 description 2
210000002966 serum Anatomy 0.000 description 2
229920002050 silicone resin Polymers 0.000 description 2
239000007787 solid Substances 0.000 description 2
239000011877 solvent mixture Substances 0.000 description 2
230000002485 urinary effect Effects 0.000 description 2
210000002700 urine Anatomy 0.000 description 2
JVDHWXLTNDKLIZ-WCCKRBBISA-N (2s)-2-amino-5-(diaminomethylideneamino)pentanoic acid;hydrate Chemical compound O.OC(=O)[C@@H](N)CCCNC(N)=N JVDHWXLTNDKLIZ-WCCKRBBISA-N 0.000 description 1
MFGOFGRYDNHJTA-UHFFFAOYSA-N 2-amino-1-(2-fluorophenyl)ethanol Chemical compound NCC(O)C1=CC=CC=C1F MFGOFGRYDNHJTA-UHFFFAOYSA-N 0.000 description 1
241000228245 Aspergillus niger Species 0.000 description 1
NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical compound C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 description 1
241000283690 Bos taurus Species 0.000 description 1
UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
235000008733 Citrus aurantifolia Nutrition 0.000 description 1
206010053567 Coagulopathies Diseases 0.000 description 1
108010093096 Immobilized Enzymes Proteins 0.000 description 1
ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 1
OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 1
241000047703 Nonion Species 0.000 description 1
239000004952 Polyamide Substances 0.000 description 1
239000002202 Polyethylene glycol Substances 0.000 description 1
229920005830 Polyurethane Foam Polymers 0.000 description 1
102000007562 Serum Albumin Human genes 0.000 description 1
108010071390 Serum Albumin Proteins 0.000 description 1
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
229910000831 Steel Inorganic materials 0.000 description 1
235000011941 Tilia x europaea Nutrition 0.000 description 1
RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical group [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
206010052428 Wound Diseases 0.000 description 1
208000027418 Wounds and injury Diseases 0.000 description 1
230000002411 adverse Effects 0.000 description 1
238000001042 affinity chromatography Methods 0.000 description 1
HAMNKKUPIHEESI-UHFFFAOYSA-N aminoguanidine Chemical compound NNC(N)=N HAMNKKUPIHEESI-UHFFFAOYSA-N 0.000 description 1
ZPNFWUPYTFPOJU-MPSLMFKFSA-N aprotinin Chemical compound CC[C@H](C)[C@@H]1NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CSSC[C@H]3NC(=O)CNC(=O)CNC(=O)[C@H](Cc4ccc(O)cc4)NC(=O)[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](CSSC[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC3=O)C(=O)N[C@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@H](CSSC[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H]3CCCN3C(=O)[C@H](N)CCCNC(N)=N)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N3CCC[C@@H]3C(=O)N3CCC[C@H]3C(=O)N[C@H](Cc3ccc(O)cc3)C(=O)N[C@H]([C@H](C)O)C(=O)NCC(=O)N3CCC[C@H]3C(=O)N2)C(=O)NCC(=O)NCC(=O)N[C@H](C)C(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](NC1=O)[C@H](C)CC)[C@@H](C)O)C(C)C ZPNFWUPYTFPOJU-MPSLMFKFSA-N 0.000 description 1
210000000013 bile duct Anatomy 0.000 description 1
229920000249 biocompatible polymer Polymers 0.000 description 1
210000001772 blood platelet Anatomy 0.000 description 1
238000000071 blow moulding Methods 0.000 description 1
HUCVOHYBFXVBRW-UHFFFAOYSA-M caesium hydroxide Inorganic materials [OH-].[Cs+] HUCVOHYBFXVBRW-UHFFFAOYSA-M 0.000 description 1
239000001110 calcium chloride Substances 0.000 description 1
235000011148 calcium chloride Nutrition 0.000 description 1
229910001628 calcium chloride Inorganic materials 0.000 description 1
AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 1
239000000920 calcium hydroxide Substances 0.000 description 1
229910001861 calcium hydroxide Inorganic materials 0.000 description 1
238000005266 casting Methods 0.000 description 1
230000010261 cell growth Effects 0.000 description 1
230000035602 clotting Effects 0.000 description 1
238000000748 compression moulding Methods 0.000 description 1
238000009833 condensation Methods 0.000 description 1
230000005494 condensation Effects 0.000 description 1
239000013068 control sample Substances 0.000 description 1
NKLPQNGYXWVELD-UHFFFAOYSA-M coomassie brilliant blue Chemical compound [Na+].C1=CC(OCC)=CC=C1NC1=CC=C(C(=C2C=CC(C=C2)=[N+](CC)CC=2C=C(C=CC=2)S([O-])(=O)=O)C=2C=CC(=CC=2)N(CC)CC=2C=C(C=CC=2)S([O-])(=O)=O)C=C1 NKLPQNGYXWVELD-UHFFFAOYSA-M 0.000 description 1
229920001577 copolymer Polymers 0.000 description 1
239000013078 crystal Substances 0.000 description 1
238000004043 dyeing Methods 0.000 description 1
230000000694 effects Effects 0.000 description 1
230000005684 electric field Effects 0.000 description 1
238000001125 extrusion Methods 0.000 description 1
210000000416 exudates and transudate Anatomy 0.000 description 1
239000004744 fabric Substances 0.000 description 1
235000013312 flour Nutrition 0.000 description 1
229910021485 fumed silica Inorganic materials 0.000 description 1
239000000499 gel Substances 0.000 description 1
229960000789 guanidine hydrochloride Drugs 0.000 description 1
239000001257 hydrogen Substances 0.000 description 1
229910052739 hydrogen Inorganic materials 0.000 description 1
230000005660 hydrophilic surface Effects 0.000 description 1
238000000338 in vitro Methods 0.000 description 1
239000007924 injection Substances 0.000 description 1
238000002347 injection Methods 0.000 description 1
238000001746 injection moulding Methods 0.000 description 1
239000004571 lime Substances 0.000 description 1
VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 description 1
239000000347 magnesium hydroxide Substances 0.000 description 1
229910001862 magnesium hydroxide Inorganic materials 0.000 description 1
210000004962 mammalian cell Anatomy 0.000 description 1
229910052751 metal Inorganic materials 0.000 description 1
239000002184 metal Substances 0.000 description 1
230000007935 neutral effect Effects 0.000 description 1
PGSADBUBUOPOJS-UHFFFAOYSA-N neutral red Chemical compound Cl.C1=C(C)C(N)=CC2=NC3=CC(N(C)C)=CC=C3N=C21 PGSADBUBUOPOJS-UHFFFAOYSA-N 0.000 description 1
210000002445 nipple Anatomy 0.000 description 1
230000000149 penetrating effect Effects 0.000 description 1
150000002978 peroxides Chemical class 0.000 description 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
239000008363 phosphate buffer Substances 0.000 description 1
230000000704 physical effect Effects 0.000 description 1
239000002504 physiological saline solution Substances 0.000 description 1
210000002381 plasma Anatomy 0.000 description 1
229910052697 platinum Inorganic materials 0.000 description 1
229920002647 polyamide Polymers 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
239000011496 polyurethane foam Substances 0.000 description 1
239000008057 potassium phosphate buffer Substances 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
229910052710 silicon Inorganic materials 0.000 description 1
239000010703 silicon Substances 0.000 description 1
239000004447 silicone coating Substances 0.000 description 1
SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(I) nitrate Inorganic materials [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
239000007921 spray Substances 0.000 description 1
238000010186 staining Methods 0.000 description 1
239000010959 steel Substances 0.000 description 1
UUCCCPNEFXQJEL-UHFFFAOYSA-L strontium dihydroxide Chemical compound [OH-].[OH-].[Sr+2] UUCCCPNEFXQJEL-UHFFFAOYSA-L 0.000 description 1
229910001866 strontium hydroxide Inorganic materials 0.000 description 1
238000004381 surface treatment Methods 0.000 description 1
229920001059 synthetic polymer Polymers 0.000 description 1
OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
210000003932 urinary bladder Anatomy 0.000 description 1
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
229920002554 vinyl polymer Polymers 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/12—Chemical modification
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2383/00—Characterised by the use of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen, or carbon only; Derivatives of such polymers
- C08J2383/04—Polysiloxanes
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S385/00—Optical waveguides
- Y10S385/90—Solar collector or transmitter
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S428/00—Stock material or miscellaneous articles
- Y10S428/907—Resistant against plant or animal attack
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31652—Of asbestos
- Y10T428/31663—As siloxane, silicone or silane

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Chemical & Material Sciences (AREA)
General Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Polymers & Plastics (AREA)
Organic Chemistry (AREA)
Materials For Medical Uses (AREA)
Treatments Of Macromolecular Shaped Articles (AREA)
Paints Or Removers (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Coating Of Shaped Articles Made Of Macromolecular Substances (AREA)

IL10569793A 1992-05-16 1993-05-13 Modification of the surface area of polysiloxane products and bedding coated by a wet chemical method IL105697A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4216271A DE4216271A1 (de)	1992-05-16	1992-05-16	Verfahren zur naßchemischen Oberflächenmodifizierung von Formkörpern aus Organopolysiloxanen sowie Verwendung der Verfahrenserzeugnisse

Publications (2)

Publication Number	Publication Date
IL105697A0 IL105697A0 (en)	1993-09-22
IL105697A true IL105697A (en)	1998-12-06

Family

ID=6459079

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL10569793A IL105697A (en)	1992-05-16	1993-05-13	Modification of the surface area of polysiloxane products and bedding coated by a wet chemical method

Country Status (12)

Country	Link
US (1)	US5494756A (de)
EP (1)	EP0603351B1 (de)
JP (1)	JPH07508053A (de)
CN (1)	CN1080937A (de)
AT (1)	ATE199163T1 (de)
AU (1)	AU670590B2 (de)
CA (1)	CA2113430A1 (de)
DE (2)	DE4216271A1 (de)
IL (1)	IL105697A (de)
MX (1)	MX9302848A (de)
TW (1)	TW227007B (de)
WO (1)	WO1993023462A1 (de)

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US5624704A (en) *	1995-04-24	1997-04-29	Baylor College Of Medicine	Antimicrobial impregnated catheters and other medical implants and method for impregnating catheters and other medical implants with an antimicrobial agent
US6033719A (en) *	1996-04-25	2000-03-07	Medtronic, Inc.	Method for covalent attachment of biomolecules to surfaces of medical devices
GB9613010D0 (en) *	1996-06-21	1996-08-28	Boc Group Plc	Medical article
US6191192B1 (en) *	1997-06-23	2001-02-20	Toyo Boseki Kabushiki Kaisha	Antibacterial polymeric moldings
CN1292806C (zh) *	2000-10-24	2007-01-03	博士伦公司	通过阳离子多糖防止细菌对生物材料的附着
GB2371304A (en) *	2001-01-16	2002-07-24	Suisse Electronique Microtech	Surface passivation of organic polymers and elastomers
US6558734B2 (en) *	2001-02-09	2003-05-06	Medtronic, Inc.	Methods for modifying surfaces of articles
FR2822383B1 (fr) *	2001-03-23	2004-12-17	Perouse Lab	Prothese pour reconstruction plastique a proprietes d'hydrophilicite ameliorees, et procede pour leur obtention
US20050079365A1 (en) *	2002-10-09	2005-04-14	Widenhouse Christopher W.	Method for the surface modification of silicone surfaces
US8425926B2 (en) *	2003-07-16	2013-04-23	Yongxing Qiu	Antimicrobial medical devices
TWI301603B (en)	2005-09-02	2008-10-01	Au Optronics Corp	Driving system and method for liquid crystal display
TWI357040B (en)	2005-09-21	2012-01-21	Mstar Semiconductor Inc	Liquid crystal display control circuit and thereof
US20080076851A1 (en) *	2006-08-28	2008-03-27	Goldberg Eugene P	Hydrophilic surface modification of contact lenses
JP5713518B2 (ja)	2006-12-08	2015-05-07	中国塗料株式会社	積層防汚塗膜、基材の防汚方法、積層防汚塗膜付き基材およびプライマー組成物
KR101426977B1 (ko) *	2007-01-31	2014-08-06	노파르티스 아게	은 나노입자를 포함하는 항균성 의료 장치
EP3154601A1 (de)	2014-06-13	2017-04-19	Hörsys GmbH	Selbstkrümmendes implantat
US9896601B2 (en)	2015-05-27	2018-02-20	Gaco Western, LLC	Dirt pick-up resistant silicone compositions
DE202016107015U1 (de)	2016-12-15	2018-03-28	Johannes Reinmüller	Implantat

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3561995A (en) *	1967-04-03	1971-02-09	M & T Chemicals Inc	Method of activating a polymer surface and resultant article
US3900617A (en) *	1973-11-27	1975-08-19	Gen Electric	Method of rendering flexible sheet material non-adherent and article produced thereby
US4332922A (en) *	1980-07-18	1982-06-01	Titmus Eurocon	Process for rendering silicone rubber contact lenses hydrophilic
US5217492A (en) *	1982-09-29	1993-06-08	Bio-Metric Systems, Inc.	Biomolecule attachment to hydrophobic surfaces
US4401718A (en) *	1982-10-29	1983-08-30	General Electric Company	Process for applying a second silicone resin coating composition over a first silicone resin coating composition
DE3533028A1 (de) *	1985-09-16	1987-03-19	Wacker Chemie Gmbh	Verfahren zum stabilisieren von organopolysiloxanen
US4789601A (en) *	1987-05-04	1988-12-06	Banes Albert J	Biocompatible polyorganosiloxane composition for cell culture apparatus
US4943460A (en) *	1988-02-19	1990-07-24	Snyder Laboratories, Inc.	Process for coating polymer surfaces and coated products produced using such process

1992
- 1992-05-16 DE DE4216271A patent/DE4216271A1/de not_active Withdrawn
1993
- 1993-05-13 JP JP6501857A patent/JPH07508053A/ja active Pending
- 1993-05-13 IL IL10569793A patent/IL105697A/en not_active IP Right Cessation
- 1993-05-13 WO PCT/US1993/004553 patent/WO1993023462A1/en not_active Ceased
- 1993-05-13 CA CA 2113430 patent/CA2113430A1/en not_active Abandoned
- 1993-05-13 EP EP93911301A patent/EP0603351B1/de not_active Expired - Lifetime
- 1993-05-13 AU AU42483/93A patent/AU670590B2/en not_active Ceased
- 1993-05-13 AT AT93911301T patent/ATE199163T1/de not_active IP Right Cessation
- 1993-05-13 DE DE69329930T patent/DE69329930D1/de not_active Expired - Lifetime
- 1993-05-14 US US08/062,646 patent/US5494756A/en not_active Expired - Fee Related
- 1993-05-14 MX MX9302848A patent/MX9302848A/es unknown
- 1993-05-15 CN CN93107069A patent/CN1080937A/zh active Pending
- 1993-05-19 TW TW82103948A patent/TW227007B/zh active

Also Published As

Publication number	Publication date
ATE199163T1 (de)	2001-02-15
AU670590B2 (en)	1996-07-25
EP0603351A1 (de)	1994-06-29
MX9302848A (es)	1994-02-28
WO1993023462A1 (en)	1993-11-25
DE69329930D1 (de)	2001-03-22
AU4248393A (en)	1993-12-13
CN1080937A (zh)	1994-01-19
TW227007B (de)	1994-07-21
JPH07508053A (ja)	1995-09-07
DE4216271A1 (de)	1993-11-18
EP0603351B1 (de)	2001-02-14
CA2113430A1 (en)	1994-01-13
IL105697A0 (en)	1993-09-22
US5494756A (en)	1996-02-27

Legal Events

Date	Code	Title
1999-06-20	FF	Patent granted
1999-10-28	KB	Patent renewed
1999-12-22	KB	Patent renewed
2004-02-08	RH1	Patent not in force

Publication	Publication Date	Title
EP0603351B1 (de)	2001-02-14	Verfahren zur nasschemischen Oberflächenmodifikation von geformten Polysiloxanen und beschichteten Substraten
US4865870A (en)	1989-09-12	Method for rendering a substrate surface antithrombogenic
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Zhang et al.	2015	Anti-fouling coatings of poly (dimethylsiloxane) devices for biological and biomedical applications
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US8524886B2 (en)	2013-09-03	Outer layer having entanglement of hydrophobic polymer host and hydrophilic polymer guest
EP0351314B1 (de)	1995-02-01	Medizinisches Material und Gerät
Tighe	1986	The role of permeability and related properties in the design of synthetic hydrogels for biomedical applications
US4657820A (en)	1987-04-14	Plastic article containing a top coat comprising an albumin and polysaccharide mixture
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JPS61176910A (ja)	1986-08-08	親水性コンタクトレンズの表面改質法
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