IL106306A - Rotavirus vaccines for injection - Google Patents

Rotavirus vaccines for injection

Info

Publication number: IL106306A
Authority: IL; Israel
Prior art keywords: vaccine; virus; rotavirus; compositions according; inoculated
Prior art date: 1992-07-10

Application number

IL10630693A

Other languages

English (en)

Hebrew (he)

Other versions

IL106306A0 (en

Inventor

Mary K Estes

Margaret E Conner

Original Assignee

Baylor College Medicine

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-07-10

Filing date

1993-07-12

Publication date

2002-07-25

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25430523&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL106306(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1993-07-12 Application filed by Baylor College Medicine filed Critical Baylor College Medicine

1993-11-15 Publication of IL106306A0 publication Critical patent/IL106306A0/xx

2002-07-25 Publication of IL106306A publication Critical patent/IL106306A/en

Links

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238000002649 immunization Methods 0.000 title description 10
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229940031626 subunit vaccine Drugs 0.000 claims abstract description 11
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238000007710 freezing Methods 0.000 description 1
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102000018358 immunoglobulin Human genes 0.000 description 1
230000000415 inactivating effect Effects 0.000 description 1
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238000010255 intramuscular injection Methods 0.000 description 1
239000007927 intramuscular injection Substances 0.000 description 1
210000003734 kidney Anatomy 0.000 description 1
230000001983 lactogenic effect Effects 0.000 description 1
229940038523 live rotavirus vaccine Drugs 0.000 description 1
239000006166 lysate Substances 0.000 description 1
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229940031348 multivalent vaccine Drugs 0.000 description 1
208000004995 necrotizing enterocolitis Diseases 0.000 description 1
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244000052769 pathogen Species 0.000 description 1
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201000006195 perinatal necrotizing enterocolitis Diseases 0.000 description 1
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235000020030 perry Nutrition 0.000 description 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
239000010452 phosphate Substances 0.000 description 1
229920000915 polyvinyl chloride Polymers 0.000 description 1
239000004800 polyvinyl chloride Substances 0.000 description 1
239000013641 positive control Substances 0.000 description 1
230000003389 potentiating effect Effects 0.000 description 1
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239000000310 rehydration solution Substances 0.000 description 1
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230000003362 replicative effect Effects 0.000 description 1
238000011160 research Methods 0.000 description 1
238000005070 sampling Methods 0.000 description 1
230000035945 sensitivity Effects 0.000 description 1
238000013207 serial dilution Methods 0.000 description 1
208000026775 severe diarrhea Diseases 0.000 description 1
210000000813 small intestine Anatomy 0.000 description 1
235000010267 sodium hydrogen sulphite Nutrition 0.000 description 1
239000000243 solution Substances 0.000 description 1
238000010254 subcutaneous injection Methods 0.000 description 1
239000007929 subcutaneous injection Substances 0.000 description 1
239000000126 substance Substances 0.000 description 1
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238000010257 thawing Methods 0.000 description 1
239000003104 tissue culture media Substances 0.000 description 1
238000004448 titration Methods 0.000 description 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
239000012588 trypsin Substances 0.000 description 1
229940125575 vaccine candidate Drugs 0.000 description 1
230000003442 weekly effect Effects 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/15—Reoviridae, e.g. calf diarrhea virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Virology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Immunology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Microbiology (AREA)
Organic Chemistry (AREA)
Mycology (AREA)
Epidemiology (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
General Engineering & Computer Science (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Catalysts (AREA)
Medicinal Preparation (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

IL10630693A 1992-07-10 1993-07-12 Rotavirus vaccines for injection IL106306A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/911,593 US6780630B1 (en)	1992-07-10	1992-07-10	Parenteral immunization against rotavirus

Publications (2)

Publication Number	Publication Date
IL106306A0 IL106306A0 (en)	1993-11-15
IL106306A true IL106306A (en)	2002-07-25

Family

ID=25430523

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL10630693A IL106306A (en)	1992-07-10	1993-07-12	Rotavirus vaccines for injection

Country Status (14)

Country	Link
US (1)	US6780630B1 (da)
EP (1)	EP0603386B1 (da)
JP (1)	JPH07501558A (da)
KR (2)	KR940702388A (da)
AT (1)	ATE211923T1 (da)
AU (1)	AU673370B2 (da)
CA (1)	CA2116971A1 (da)
DE (1)	DE69331459T2 (da)
DK (1)	DK0603386T3 (da)
ES (1)	ES2166763T3 (da)
IL (1)	IL106306A (da)
NO (1)	NO307815B1 (da)
PT (1)	PT603386E (da)
WO (1)	WO1994001134A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5626851A (en) *	1987-11-30	1997-05-06	The Wistar Institute Of Anatomy And Biology	Rotavirus reassortant vaccine
US6210677B1 (en) *	1993-01-29	2001-04-03	Robert C. Bohannon	Method to reduce the physiologic effects of drugs on mammals
CA2224697A1 (en)	1995-06-14	1997-01-03	Peng Tian	Rotavirus enterotoxin nsp4 and methods of using same
US6673355B1 (en)	1995-06-14	2004-01-06	Baylor College Of Medicine	Rotavirus enterotoxin NSP4 and methods of using same
CA2698392C (en)	2007-09-04	2019-12-03	Baoming Jiang	Thermal inactivation of rotavirus
CA3121471A1 (en)	2009-05-12	2010-11-18	The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention	New human rotavirus strains and vaccines
EP3169313B1 (en) *	2014-07-18	2019-08-28	Msd Wellcome Trust Hilleman Laboratories Pvt. Ltd.	A thermostable freeze dried rotavirus vaccine formulation and process to prepare thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2483779A1 (fr) *	1980-06-05	1981-12-11	Synthelabo	Procede pour isoler des antigenes glycoproteiques viraux et son application a la preparation de vaccins
US4341763A (en) *	1981-03-10	1982-07-27	Smithkline-Rit	Methods of vaccinating humans against rotavirus infection
US4636385A (en) *	1985-02-15	1987-01-13	The Wistar Institute Of Anatomy & Biology	Vaccine, method for its preparation, and use thereof in vaccinating humans against rotavirus infection
US4861864A (en) *	1985-05-14	1989-08-29	Albert Einstein College of Medicine of Yeshiva University (a Div. of Yeshiva University)	Rotavirus antigens
US4704275A (en) *	1985-08-26	1987-11-03	The United States Of America As Represented By The Department Of Health And Human Services	Vaccine against rotavirus diseases
EP0251467A3 (en) *	1986-06-20	1988-07-20	Abbott Laboratories	Compositions and methods of use for a major outer capsid protein (vp7) of rotavirus sa-11
US4927628A (en) *	1987-09-21	1990-05-22	The United States Of America As Represented By The Department Of Health And Human Services	Vaccine against rotavirus diseases and method of preparing same
US5147639A (en) *	1990-06-19	1992-09-15	Ambico, Inc.	Type-c rotavirus cultures and uses therefor
WO1992008786A1 (en) *	1990-11-16	1992-05-29	James N. Gamble Institute Of Medical Research	Human rotaviruses, vaccines and methods

1992
- 1992-07-10 US US07/911,593 patent/US6780630B1/en not_active Expired - Fee Related
1993
- 1993-07-12 JP JP6503564A patent/JPH07501558A/ja not_active Ceased
- 1993-07-12 AT AT93917119T patent/ATE211923T1/de not_active IP Right Cessation
- 1993-07-12 EP EP93917119A patent/EP0603386B1/en not_active Revoked
- 1993-07-12 KR KR1019940700778A patent/KR940702388A/ko not_active Ceased
- 1993-07-12 DK DK93917119T patent/DK0603386T3/da active
- 1993-07-12 DE DE69331459T patent/DE69331459T2/de not_active Expired - Fee Related
- 1993-07-12 ES ES93917119T patent/ES2166763T3/es not_active Expired - Lifetime
- 1993-07-12 AU AU46740/93A patent/AU673370B2/en not_active Ceased
- 1993-07-12 CA CA002116971A patent/CA2116971A1/en not_active Abandoned
- 1993-07-12 PT PT93917119T patent/PT603386E/pt unknown
- 1993-07-12 KR KR1020017006840A patent/KR100354587B1/ko not_active Expired - Fee Related
- 1993-07-12 WO PCT/US1993/006543 patent/WO1994001134A1/en not_active Ceased
- 1993-07-12 IL IL10630693A patent/IL106306A/en not_active IP Right Cessation
1994
- 1994-03-09 NO NO940827A patent/NO307815B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
JPH07501558A (ja)	1995-02-16
ES2166763T3 (es)	2002-05-01
ATE211923T1 (de)	2002-02-15
CA2116971A1 (en)	1994-01-20
DK0603386T3 (da)	2002-03-11
NO940827D0 (no)	1994-03-09
KR100354587B1 (ko)	2002-10-04
US6780630B1 (en)	2004-08-24
KR940702388A (ko)	1994-08-20
EP0603386A4 (en)	1996-05-29
AU4674093A (en)	1994-01-31
PT603386E (pt)	2002-06-28
NO307815B1 (no)	2000-06-05
WO1994001134A1 (en)	1994-01-20
DE69331459T2 (de)	2002-06-20
NO940827L (no)	1994-05-09
DE69331459D1 (de)	2002-02-21
AU673370B2 (en)	1996-11-07
EP0603386A1 (en)	1994-06-29
EP0603386B1 (en)	2002-01-16
IL106306A0 (en)	1993-11-15

Legal Events

Date	Code	Title
2003-01-12	FF	Patent granted
2003-07-31	KB	Patent renewed
2003-09-17	KB	Patent renewed
2008-03-23	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
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