IL111364A0 - Delta 16 unsaturated c17 heterocyclic steroids useful as steroid c17-20 lyase inhibitors - Google Patents

Delta 16 unsaturated c17 heterocyclic steroids useful as steroid c17-20 lyase inhibitors

Info

Publication number
IL111364A0
IL111364A0 IL11136494A IL11136494A IL111364A0 IL 111364 A0 IL111364 A0 IL 111364A0 IL 11136494 A IL11136494 A IL 11136494A IL 11136494 A IL11136494 A IL 11136494A IL 111364 A0 IL111364 A0 IL 111364A0
Authority
IL
Israel
Prior art keywords
steroid
delta
unsaturated
lyase inhibitors
steroids useful
Prior art date
Application number
IL11136494A
Other languages
English (en)
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL111364A0 publication Critical patent/IL111364A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL11136494A 1993-10-27 1994-10-23 Delta 16 unsaturated c17 heterocyclic steroids useful as steroid c17-20 lyase inhibitors IL111364A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14367993A 1993-10-27 1993-10-27

Publications (1)

Publication Number Publication Date
IL111364A0 true IL111364A0 (en) 1994-12-29

Family

ID=22505119

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11136494A IL111364A0 (en) 1993-10-27 1994-10-23 Delta 16 unsaturated c17 heterocyclic steroids useful as steroid c17-20 lyase inhibitors

Country Status (19)

Country Link
US (3) US5677293A (de)
EP (1) EP0724591B1 (de)
JP (1) JPH09511214A (de)
KR (1) KR960705838A (de)
CN (1) CN1046736C (de)
AT (1) ATE177751T1 (de)
AU (2) AU684844B2 (de)
CA (1) CA2173729C (de)
DE (1) DE69417248T2 (de)
DK (1) DK0724591T3 (de)
ES (1) ES2133582T3 (de)
FI (1) FI961792A0 (de)
GR (1) GR3030263T3 (de)
HU (1) HUT73855A (de)
IL (1) IL111364A0 (de)
NO (1) NO961693L (de)
NZ (1) NZ274694A (de)
WO (1) WO1995011914A1 (de)
ZA (1) ZA948310B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2347027T3 (es) 1998-05-22 2010-10-22 The Board Of Trustees Of The Leland Stanford Junior University Moleculas bifuncionales y terapias basadas en las mismas.
WO2001005364A1 (en) * 1999-07-15 2001-01-25 The Procter & Gamble Company Nitrogen-containing steroid compounds and their use to regulate hair growth
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
US6562457B1 (en) 2001-10-31 2003-05-13 E. I. Du Pont De Nemours And Company Polyether ester elastomer comprising polytrimethylene ether ester soft segment and tetramethylene ester hard segment
US8569275B2 (en) 2002-08-28 2013-10-29 Harbor Therapeutics, Inc. Steroids having 7-oxgen and 17-heteroaryl substitution
EP2671507A3 (de) 2005-04-28 2014-02-19 Proteus Digital Health, Inc. Pharma-Informatiksystem
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
CA2752373C (en) 2009-02-20 2017-10-10 To-Bbb Holding B.V. Glutathione-based drug delivery system
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
WO2011088160A2 (en) * 2010-01-15 2011-07-21 Biomarin Pharmaceutical Inc. Novel cyp17 inhibitors
KR101823275B1 (ko) 2010-08-04 2018-03-08 펠피큐어 파마슈티걸즈 아이엔씨 전립선 암종의 치료를 위한 병용 요법
CN102746358B (zh) * 2011-04-22 2016-02-10 天津金耀集团有限公司 一种合成孕甾21位溴化物的工艺
CN102898495B (zh) * 2012-11-12 2014-11-26 浙江神洲药业有限公司 醋酸阿比特龙酯的制备方法
CN103059091B (zh) * 2012-11-22 2017-04-19 常州靶点医药科技有限公司 一种避免重金属残留的醋酸阿比特龙的制备方法
EP2968219B1 (de) 2013-03-14 2019-04-24 Pellficure Pharmaceuticals, Inc. Neuartige therapie gegen prostatakarzinome
EP3191087A1 (de) 2014-09-12 2017-07-19 Pellficure Pharmaceuticals, Inc. Zusammensetzungen und verfahren zur behandlung von prostatakrebs
HUP1500055A1 (hu) 2015-02-09 2016-08-29 Druggability Technologies Ip Holdco Ltd Abirateron acetát komplexei, eljárás elõállításukra, és az azokat tartalmazó gyógyászati készítmények
EP3528799A1 (de) 2016-10-24 2019-08-28 Pellficure Pharmaceuticals, Inc. Pharmazeutische zusammensetzungen aus 5-hydroxy-2-methylnaphthalen-1,4-dion
CN106866773A (zh) * 2017-02-14 2017-06-20 西北农林科技大学 一组具有抗癌活性吡唑基甾体衍生物的制备方法及应用
CN116621905B (zh) * 2023-06-06 2025-07-15 西北农林科技大学 双烯噻唑类衍生物及其合成方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1081647A (en) * 1965-04-01 1967-08-31 Shionogi & Co Furan compounds
AT253975B (de) * 1965-06-15 1967-05-10 Carinthia Elektrogeraete Ges M Trockenrasierapparat
US3398138A (en) * 1966-05-24 1968-08-20 American Home Prod Novel cardenolides and derivatives
US3436390A (en) * 1966-05-24 1969-04-01 American Home Prod 4,4-dihydroxy-2-butenoic acid lactones
US4259240A (en) * 1979-09-28 1981-03-31 Advance Biofactures Corporation Synthesis of furyl intermediates, and cardenolides and their isomers prepared therefrom
US4380624A (en) * 1981-07-31 1983-04-19 Advance Biofactures Corp. Novel isomers of bufalin and resibufogenin and their preparation
US4523917A (en) * 1983-12-27 1985-06-18 Dana Corporation Variable pitch diameter torque sensing pulley assembly
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
GB2265624B (en) * 1992-03-31 1995-04-19 British Tech Group 17-substituted steroids useful in cancer treatment
DE4221636C1 (de) * 1992-07-01 1994-03-31 Sigma Tau Ind Farmaceuti Cyclopentanperhydrophenanthren-17beta-(3-furyl)-3-Derivate

Also Published As

Publication number Publication date
AU684844B2 (en) 1998-01-08
AU7922394A (en) 1995-05-22
EP0724591B1 (de) 1999-03-17
ATE177751T1 (de) 1999-04-15
HU9601113D0 (en) 1996-07-29
FI961792L (fi) 1996-04-26
JPH09511214A (ja) 1997-11-11
CN1133596A (zh) 1996-10-16
WO1995011914A1 (en) 1995-05-04
CA2173729C (en) 2001-05-15
FI961792A7 (fi) 1996-04-26
NO961693D0 (no) 1996-04-26
AU3993097A (en) 1998-01-08
CA2173729A1 (en) 1995-05-04
DE69417248T2 (de) 1999-08-19
US5965548A (en) 1999-10-12
HUT73855A (en) 1996-09-30
DK0724591T3 (da) 1999-09-27
US5677293A (en) 1997-10-14
KR960705838A (ko) 1996-11-08
ZA948310B (en) 1995-06-14
NZ274694A (en) 1998-01-26
CN1046736C (zh) 1999-11-24
ES2133582T3 (es) 1999-09-16
NO961693L (no) 1996-04-26
AU695341B2 (en) 1998-08-13
GR3030263T3 (en) 1999-08-31
FI961792A0 (fi) 1996-04-26
DE69417248D1 (de) 1999-04-22
US5977094A (en) 1999-11-02
EP0724591A1 (de) 1996-08-07

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