IL112849A - Isoxazoline compounds as 5-lipoxygenase inhibitors - Google Patents

Isoxazoline compounds as 5-lipoxygenase inhibitors

Info

Publication number: IL112849A
Authority: IL; Israel
Prior art keywords: lipoxygenase inhibitors; isoxazoline compounds; isoxazoline; compounds; lipoxygenase
Prior art date: 1994-03-09

Application number

IL11284995A

Other languages

English (en)

Other versions

IL112849A0 (en

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-03-09

Filing date

1995-03-02

Publication date

1999-04-11

1995-03-02 Application filed by Pfizer filed Critical Pfizer

1995-06-29 Publication of IL112849A0 publication Critical patent/IL112849A0/xx

1999-04-11 Publication of IL112849A publication Critical patent/IL112849A/xx

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Nutrition Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

IL11284995A 1994-03-09 1995-03-02 Isoxazoline compounds as 5-lipoxygenase inhibitors IL112849A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US20876894A	1994-03-09	1994-03-09

Publications (2)

Publication Number	Publication Date
IL112849A0 IL112849A0 (en)	1995-06-29
IL112849A true IL112849A (en)	1999-04-11

Family

ID=22775981

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11284995A IL112849A (en)	1994-03-09	1995-03-02	Isoxazoline compounds as 5-lipoxygenase inhibitors

Country Status (11)

Country	Link
US (1)	US5696141A (fr)
EP (1)	EP0749307A1 (fr)
JP (1)	JPH09505081A (fr)
AU (1)	AU1326795A (fr)
CA (1)	CA2184914C (fr)
FI (1)	FI963509A7 (fr)
IL (1)	IL112849A (fr)
MX (1)	MX9603943A (fr)
MY (1)	MY112586A (fr)
WO (1)	WO1995024192A1 (fr)
ZA (1)	ZA951911B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN107233337A (zh)	2009-04-29	2017-10-10	阿马里纳药物爱尔兰有限公司	含有epa和心血管剂的药物组合物以及使用其的方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS62103070A (ja) *	1985-10-29	1987-05-13	Mitsui Toatsu Chem Inc	イソオキサゾリン誘導体および植物生長調節剤
HU215433B (hu) *	1986-04-29	2000-05-28	Pfizer Inc.	Eljárás új 2-oxo-5-fenil-pirimidin-származékok előállítására
IE59813B1 (en) *	1986-05-09	1994-04-06	Warner Lambert Co	Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them
US4731382A (en) *	1986-12-29	1988-03-15	Bristol-Myers Company	Lipoxygenase inhibitory phenylalkanohydroxamic acids
FR2639636B1 (fr) *	1988-11-30	1994-03-04	Novapharme	Nouveaux composes heterocycliques a activite anticonvulsivante, procede de preparation et compositions therapeutiques les contenant
IL92915A0 (en) *	1989-01-05	1990-09-17	Ciba Geigy Ag	Certain pyrrolylphenyl-substituted hydroxamic acid derivatives
CA2017383A1 (fr) *	1989-06-08	1990-12-08	Raymond R. Martodam	Utilisation de vanilloides pour le traitement des affections ou des troubles respiratoires
WO1991007177A1 (fr) *	1989-11-13	1991-05-30	Pfizer Inc.	Derives de pyrimidone et analogues pour le traitement de l'asthme et de certaines maladies de la peau
DE3939010A1 (de) *	1989-11-25	1991-05-29	Hoechst Ag	Isoxazoline, verfahren zu ihrer herstellung und ihre verwendung als pflanzenschuetzende mittel
JP2787602B2 (ja) *	1990-01-24	1998-08-20	大鵬薬品工業株式会社	イソキサゾリン誘導体
US5234937A (en) *	1990-03-27	1993-08-10	Warner-Lambert Company	3,5-di-tertiary-butyl-4-hydroxphenyl oxazolyl methanones and related compounds as antiinflammatory agents
GB9007762D0 (en) *	1990-04-05	1990-06-06	Beecham Group Plc	Novel compounds
KR930703262A (ko) *	1990-11-06	1993-11-29	스튜어트 알. 슈터	이미다졸리디논 화합물
PT100441A (pt) *	1991-05-02	1993-09-30	Smithkline Beecham Corp	Pirrolidinonas, seu processo de preparacao, composicoes farmaceuticas que as contem e uso
US5140047A (en) *	1991-05-03	1992-08-18	Smithkline Beecham Corporation	Lipoxygenase inhibitors
GB9215921D0 (en) *	1992-07-27	1992-09-09	Wellcome Found	Anti-inflammatory compounds
US5288397A (en) *	1992-09-18	1994-02-22	Mobil Oil Corporation	Baffled FCC regeneration process and apparatus
WO1994018158A1 (fr) *	1993-02-15	1994-08-18	Pfizer Inc.	Spiroalkylhydroxyurees utilisees comme inhibiteurs de lipoxygenase

1995
- 1995-01-19 MX MX9603943A patent/MX9603943A/es not_active IP Right Cessation
- 1995-01-19 WO PCT/IB1995/000041 patent/WO1995024192A1/fr not_active Ceased
- 1995-01-19 CA CA002184914A patent/CA2184914C/fr not_active Expired - Fee Related
- 1995-01-19 JP JP7523327A patent/JPH09505081A/ja active Pending
- 1995-01-19 US US08/700,432 patent/US5696141A/en not_active Expired - Fee Related
- 1995-01-19 EP EP95904684A patent/EP0749307A1/fr not_active Withdrawn
- 1995-01-19 AU AU13267/95A patent/AU1326795A/en not_active Abandoned
- 1995-01-19 FI FI963509A patent/FI963509A7/fi unknown
- 1995-03-02 IL IL11284995A patent/IL112849A/xx not_active IP Right Cessation
- 1995-03-07 MY MYPI95000574A patent/MY112586A/en unknown
- 1995-03-08 ZA ZA951911A patent/ZA951911B/xx unknown

Also Published As

Publication number	Publication date
EP0749307A1 (fr)	1996-12-27
JPH09505081A (ja)	1997-05-20
US5696141A (en)	1997-12-09
WO1995024192A1 (fr)	1995-09-14
CA2184914C (fr)	2000-09-19
CA2184914A1 (fr)	1995-09-14
AU1326795A (en)	1995-09-25
FI963509L (fi)	1996-09-06
FI963509A0 (fi)	1996-09-06
MY112586A (en)	2001-07-31
IL112849A0 (en)	1995-06-29
MX9603943A (es)	1997-04-30
ZA951911B (en)	1996-09-09
FI963509A7 (fi)	1996-09-06

Legal Events

Date	Code	Title
1999-08-17	FF	Patent granted
2000-06-01	KB	Patent renewed
2001-06-14	KB	Patent renewed
2006-01-15	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
GB9407812D0 (en)	1994-06-15	Compounds
GB9414193D0 (en)	1994-08-31	Compounds
GB9414208D0 (en)	1994-08-31	Compounds
GB9404706D0 (en)	1994-04-27	Compounds
GB9406043D0 (en)	1994-05-18	Compounds
GB9409921D0 (en)	1994-07-06	Compounds
GB9407435D0 (en)	1994-06-08	Compounds
GB9403199D0 (en)	1994-04-13	Compounds
GB9417938D0 (en)	1994-10-26	Compounds
GB9400413D0 (en)	1994-03-09	Compounds
IL112849A0 (en)	1995-06-29	Isoxazoline compounds as 5-lipoxygenase inhibitors
GB9402041D0 (en)	1994-03-30	Compounds
ZA945085B (en)	1995-02-22	5-Lipoxygenase inhibitors
GB9402603D0 (en)	1994-04-06	Compounds
GB9420111D0 (en)	1994-11-16	Heterocycle compounds
GB2296241B (en)	1998-07-08	Compounds
GB9426032D0 (en)	1995-02-22	0rganic compounds
GB9426027D0 (en)	1995-02-22	0rganic compounds
GB9417707D0 (en)	1994-10-19	Metaloganic compounds
GB9408524D0 (en)	1994-06-22	Compounds
GB9406181D0 (en)	1994-05-18	Compounds
GB9414868D0 (en)	1994-09-14	Compounds
GB9414784D0 (en)	1994-09-14	Compounds
GB9411482D0 (en)	1994-07-27	Compounds
GB9409876D0 (en)	1994-07-06	Compounds