IL114852A - Pharmaceutically stable preparation of oxaliplatinum - Google Patents

Pharmaceutically stable preparation of oxaliplatinum

Info

Publication number
IL114852A
IL114852A IL11485295A IL11485295A IL114852A IL 114852 A IL114852 A IL 114852A IL 11485295 A IL11485295 A IL 11485295A IL 11485295 A IL11485295 A IL 11485295A IL 114852 A IL114852 A IL 114852A
Authority
IL
Israel
Prior art keywords
oxaliplatinum
pct
pharmaceutically stable
stable preparation
preparation
Prior art date
Application number
IL11485295A
Other languages
English (en)
Other versions
IL114852A0 (en
Inventor
Rolland-Yves Mauvernay
Houssam Ibrahim
Original Assignee
Debiopharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50845249&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL114852(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Debiopharm Sa filed Critical Debiopharm Sa
Publication of IL114852A0 publication Critical patent/IL114852A0/xx
Publication of IL114852A publication Critical patent/IL114852A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL11485295A 1994-08-08 1995-08-07 Pharmaceutically stable preparation of oxaliplatinum IL114852A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH246294 1994-08-08

Publications (2)

Publication Number Publication Date
IL114852A0 IL114852A0 (en) 1995-12-08
IL114852A true IL114852A (en) 2000-02-29

Family

ID=50845249

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11485295A IL114852A (en) 1994-08-08 1995-08-07 Pharmaceutically stable preparation of oxaliplatinum

Country Status (17)

Country Link
US (1) US5716988A (de)
EP (1) EP0774963B1 (de)
JP (1) JP3547755B2 (de)
KR (1) KR100365171B1 (de)
CN (1) CN1138541C (de)
AT (1) ATE197249T1 (de)
AU (2) AU2989695A (de)
BR (1) BR9508554A (de)
CA (1) CA2196922C (de)
CZ (1) CZ286714B6 (de)
DE (1) DE69519300T2 (de)
DK (1) DK0774963T3 (de)
ES (1) ES2152412T3 (de)
IL (1) IL114852A (de)
RU (1) RU2148400C1 (de)
UA (1) UA42779C2 (de)
WO (1) WO1996004904A1 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
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AU2989695A (en) 1994-08-08 2000-03-07 Debiopharm S.A. Pharmaceutically stable oxaliplatinum preparation
GB9804013D0 (en) * 1998-02-25 1998-04-22 Sanofi Sa Formulations
US6866857B1 (en) * 1998-10-14 2005-03-15 Debiopharm S.A. Oxalipatinum preparation packaging
GB9904386D0 (en) * 1999-02-25 1999-04-21 Pharmacia & Upjohn Spa Antitumour synergistic composition
RU2252022C2 (ru) * 1999-08-30 2005-05-20 Дебиофарм С.А. Стабильный фармацевтический препарат оксалиплатины для парентерального введения
US7070796B1 (en) * 1999-08-30 2006-07-04 Debiopharm S.A. Pharmaceutically stable oxaliplatinum preparation for parenteral administration
WO2002047725A2 (fr) * 2000-12-12 2002-06-20 Debiopharm S.A. Preparation pharmaceutique d'oxaliplatine pour administration par voie parenterale et procede d'obtention de ladite preparation
DE20221679U1 (de) * 2001-03-02 2006-11-23 Debiopharm S.A. Vorrichtung zur Konditionierung einer Oxaliplatinlösung
US20040186172A1 (en) * 2001-07-02 2004-09-23 Houssam Ibrahim Oxaliplatin active substance with a very low content of oxalic acid
TWI315982B (en) 2001-07-19 2009-10-21 Novartis Ag Combinations comprising epothilones and pharmaceutical uses thereof
US6476068B1 (en) 2001-12-06 2002-11-05 Pharmacia Italia, S.P.A. Platinum derivative pharmaceutical formulations
CA2388352A1 (en) * 2002-05-31 2003-11-30 Voiceage Corporation A method and device for frequency-selective pitch enhancement of synthesized speed
US20040022842A1 (en) * 2002-06-03 2004-02-05 Mebiopharm Co., Ltd. Liposome preparations containing oxaliplatin
CN101703467A (zh) * 2003-08-28 2010-05-12 梅恩医药有限公司 含有酸的奥沙利铂制剂
EP2330110A1 (de) 2003-11-25 2011-06-08 Platco Technologies (Proprietary) Limited Platin(II) Komplexe, Herstellung und Verwendung
CN100471493C (zh) * 2003-12-17 2009-03-25 梅比欧法姆股份有限公司 含有奥沙利铂的脂质体制剂
NZ551637A (en) * 2004-06-09 2010-05-28 Taiho Pharmaceutical Co Ltd Antitumor effect fortifier, antitumor agent and method of therapy for cancer
DK1789427T3 (da) 2004-09-01 2009-09-07 Platco Technologies Proprietar Fremstilling af platin(II)-komplekser
US20060063720A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Oxaliplatin solution concentrate
US20060063833A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Ready-to-use oxaliplatin solutions
DE102004052877B4 (de) * 2004-11-02 2008-06-19 Ebewe Pharma Ges.M.B.H. Nfg.Kg Stabile wässrige Formulierungen eines Platin-Derivats
JP2006248978A (ja) * 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
WO2007029268A2 (en) 2005-09-05 2007-03-15 Dabur Pharma Limited Stable oxaliplatin formulation
US7956208B2 (en) 2006-01-30 2011-06-07 Platco Technologies (Proprietary) Limited Preparation of platinum (II) complexes
WO2007109184A2 (en) * 2006-03-16 2007-09-27 Bionumerik Pharmaceuticals, Inc. Anti-cancer activity augmentation compounds and formulations and methods of use thereof
NZ572299A (en) 2006-05-09 2010-07-30 Novartis Ag Combination comprising a substituted 3,5-diphenyl-1,2,4-triazole and a platinum compound and use thereof
EP2441464B1 (de) * 2007-01-18 2014-04-09 Merck Patent GmbH Integrin-liganden zur verwendung in der behandlung von darmkrebs
US20090076139A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched oxalplatin
US20100267824A1 (en) * 2007-11-12 2010-10-21 Intas Pharmaceuticals Limited Stable oxaliplatin composition for parenteral administration
AU2008352597B2 (en) 2008-03-14 2012-03-08 Bionumerik Pharmaceuticals, Inc. Treatment methods and compositions for lung cancer, adenocarcinoma, and other medical conditions
JP5667886B2 (ja) 2008-03-14 2015-02-12 バイオニューメリック・ファーマスーティカルズ・インコーポレイテッド 癌患者の生存時間を増大させるための組成物及び化合物の使用方法
IN2012DN02576A (de) 2009-09-21 2015-08-28 Jw Pharmaceutical Corportion
US20130096170A1 (en) 2011-10-14 2013-04-18 Hospira, Inc. Methods of treating pediatric patients using dexmedetomidine
US8242158B1 (en) * 2012-01-04 2012-08-14 Hospira, Inc. Dexmedetomidine premix formulation
AU2013202575B1 (en) * 2012-01-04 2013-05-16 Hospira, Inc. Dexmedetomidine premix formulation
JP5314790B1 (ja) * 2012-07-09 2013-10-16 東和薬品株式会社 オキサリプラチン含有医薬組成物
EP2883542B1 (de) 2012-08-10 2019-05-01 Taiho Pharmaceutical Co., Ltd. Stabile oxaliplatin-verkapselnde wässrige liposomdispersion und stabilisierungsverfahren dafür
PE20150964A1 (es) 2012-09-07 2015-07-25 Coherus Biosciences Inc Formulaciones acuosas estables de adalimumab
CN103690494B (zh) * 2013-11-29 2015-04-15 杭州华东医药集团新药研究院有限公司 一种低杂质含有奥沙利铂的组合物及其制备方法
EP3797768A1 (de) 2014-06-23 2021-03-31 Placon Therapeutics, Inc. Maleimid-funktionalisiertes platin zur behandlung von krebs
PT3865484T (pt) 2015-07-07 2024-01-30 H Lundbeck As Inibidor da pde9 com esqueleto de imidazo pirazinona para tratamento de doenças periféricas
CN104940151A (zh) * 2015-07-23 2015-09-30 青岛蓝盛洋医药生物科技有限责任公司 一种抗癌药物奥沙利铂冻干粉针剂组合物
US11229702B1 (en) 2015-10-28 2022-01-25 Coherus Biosciences, Inc. High concentration formulations of adalimumab
US11071782B2 (en) 2016-04-20 2021-07-27 Coherus Biosciences, Inc. Method of filling a container with no headspace
WO2017192290A1 (en) 2016-05-04 2017-11-09 The Wistar Institute Of Anatomy And Biology Methods of treating cancers overexpressing carm1 with ezh2 inhibitors and platinum-based antineoplastic drugs
MX2018016127A (es) 2016-07-06 2019-05-30 Imara Inc Inhibidores de pde9 para el tratamiento de enfermedades perifericas.
CN115746003B (zh) 2017-05-26 2024-08-09 卡都瑞恩医药公司 制备和使用pde9抑制剂的方法
CA3100988A1 (en) 2018-05-25 2019-11-28 Imara Inc. Monohydrate and crystalline forms of 6-[(3s,4s)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7h-imidazo[1,5-a]pyrazin-8-one
CA3110680A1 (en) 2018-08-31 2020-03-05 Imara Inc. Pde9 inhibitors for treating sickle cell disease

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
US4657927A (en) * 1978-05-04 1987-04-14 Research Corporation Malonato platinum compounds
IL83380A (en) * 1987-07-30 1991-04-15 Teva Pharma Stable aqueous cisplatin solutions
NL8901433A (nl) * 1989-06-06 1991-01-02 Pharmachemie Bv Carboplatinpreparaat.
JPH04185601A (ja) * 1990-11-20 1992-07-02 Unitika Ltd 白金抗癌剤徐放性製剤
JP2673331B2 (ja) 1993-01-12 1997-11-05 田中貴金属工業 株式会社 光学的に高純度なシス―オキザラート（トランス―１―１，２―シクロヘキサンジアミン）白金（▲ｉｉ▼）
AU5416394A (en) * 1992-11-24 1994-06-22 Debiopharm S.A. Cisplatinum/oxaliplatinum combination
US5455270A (en) * 1993-08-11 1995-10-03 Bristol-Myers Squibb Co. Stabilized solutions of platinum(II) antitumor agents
AU2989695A (en) 1994-08-08 2000-03-07 Debiopharm S.A. Pharmaceutically stable oxaliplatinum preparation

Also Published As

Publication number Publication date
EP0774963B1 (de) 2000-11-02
CZ286714B6 (en) 2000-06-14
BR9508554A (pt) 1997-11-25
UA42779C2 (uk) 2001-11-15
AU2252499A (en) 2000-03-23
AU731981B2 (en) 2001-04-12
DE69519300T2 (de) 2001-05-31
JP3547755B2 (ja) 2004-07-28
ES2152412T3 (es) 2001-02-01
CZ37997A3 (en) 1997-06-11
IL114852A0 (en) 1995-12-08
AU2989695A (en) 2000-03-07
WO1996004904A1 (fr) 1996-02-22
DE69519300D1 (de) 2000-12-07
CN1138541C (zh) 2004-02-18
JPH10508289A (ja) 1998-08-18
ATE197249T1 (de) 2000-11-15
DK0774963T3 (da) 2001-01-29
CN1154654A (zh) 1997-07-16
CA2196922C (fr) 2004-06-01
EP0774963A1 (de) 1997-05-28
KR100365171B1 (ko) 2003-02-19
KR970704434A (ko) 1997-09-06
RU2148400C1 (ru) 2000-05-10
US5716988A (en) 1998-02-10
CA2196922A1 (fr) 1996-02-22

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