IL114852A - Pharmaceutically stable preparation of oxaliplatinum - Google Patents

Pharmaceutically stable preparation of oxaliplatinum

Info

Publication number: IL114852A
Authority: IL; Israel
Prior art keywords: oxaliplatinum; pct; pharmaceutically stable; stable preparation; preparation
Prior art date: 1994-08-08

Application number

IL11485295A

Other languages

English (en)

Other versions

IL114852A0 (en

Inventor

Rolland-Yves Mauvernay

Houssam Ibrahim

Original Assignee

Debiopharm Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-08-08

Filing date

1995-08-07

Publication date

2000-02-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50845249&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL114852(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-08-07 Application filed by Debiopharm Sa filed Critical Debiopharm Sa

1995-12-08 Publication of IL114852A0 publication Critical patent/IL114852A0/xx

2000-02-29 Publication of IL114852A publication Critical patent/IL114852A/xx

Links

239000007864 aqueous solution Substances 0.000 abstract 1
238000007911 parenteral administration Methods 0.000 abstract 1
239000000243 solution Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Inorganic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL11485295A 1994-08-08 1995-08-07 Pharmaceutically stable preparation of oxaliplatinum IL114852A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH246294		1994-08-08

Publications (2)

Publication Number	Publication Date
IL114852A0 IL114852A0 (en)	1995-12-08
IL114852A true IL114852A (en)	2000-02-29

Family

ID=50845249

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11485295A IL114852A (en)	1994-08-08	1995-08-07	Pharmaceutically stable preparation of oxaliplatinum

Country Status (17)

Country	Link
US (1)	US5716988A (de)
EP (1)	EP0774963B1 (de)
JP (1)	JP3547755B2 (de)
KR (1)	KR100365171B1 (de)
CN (1)	CN1138541C (de)
AT (1)	ATE197249T1 (de)
AU (2)	AU2989695A (de)
BR (1)	BR9508554A (de)
CA (1)	CA2196922C (de)
CZ (1)	CZ286714B6 (de)
DE (1)	DE69519300T2 (de)
DK (1)	DK0774963T3 (de)
ES (1)	ES2152412T3 (de)
IL (1)	IL114852A (de)
RU (1)	RU2148400C1 (de)
UA (1)	UA42779C2 (de)
WO (1)	WO1996004904A1 (de)

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JP3547755B2 (ja)	1994-08-08	2004-07-28	デビオファーム・エス・アー	オキサリプラティヌムの医薬的に安定な製剤
GB9804013D0 (en) *	1998-02-25	1998-04-22	Sanofi Sa	Formulations
US6866857B1 (en) *	1998-10-14	2005-03-15	Debiopharm S.A.	Oxalipatinum preparation packaging
GB9904386D0 (en) *	1999-02-25	1999-04-21	Pharmacia & Upjohn Spa	Antitumour synergistic composition
US7070796B1 (en) *	1999-08-30	2006-07-04	Debiopharm S.A.	Pharmaceutically stable oxaliplatinum preparation for parenteral administration
CA2382389C (fr) *	1999-08-30	2010-06-29	Debiopharm S.A.	Preparation pharmaceutique stable d'oxaliplatine pour administration par voie parenterale
AU2002223013A1 (en) *	2000-12-12	2002-06-24	Debiopharm S.A.	Pharmaceutical oxaliplatinum preparation for parenteral administration and method for obtaining same
EP1368022B1 (de)	2001-03-02	2007-06-20	Debiopharm S.A.	Verwendung eines eine oxaliplatinlösung beinhaltenden fläschchens
EP1404689A1 (de) *	2001-07-02	2004-04-07	Debiopharm S.A.	Aktive oxiplatinverbindung mit sehr niedrigem oxalsaüregehalt
TWI315982B (en)	2001-07-19	2009-10-21	Novartis Ag	Combinations comprising epothilones and pharmaceutical uses thereof
US6476068B1 (en)	2001-12-06	2002-11-05	Pharmacia Italia, S.P.A.	Platinum derivative pharmaceutical formulations
CA2388352A1 (en) *	2002-05-31	2003-11-30	Voiceage Corporation	A method and device for frequency-selective pitch enhancement of synthesized speed
US20040022842A1 (en) *	2002-06-03	2004-02-05	Mebiopharm Co., Ltd.	Liposome preparations containing oxaliplatin
CN102048723A (zh)	2003-08-28	2011-05-11	梅恩医药有限公司	含有酸的奥沙利铂制剂
ZA200604529B (en) *	2003-11-25	2007-12-27	Platco Technologies Proprietar	Platinum (II) complexes, preparation and use
CN100471493C (zh) *	2003-12-17	2009-03-25	梅比欧法姆股份有限公司	含有奥沙利铂的脂质体制剂
WO2005120480A1 (ja) *	2004-06-09	2005-12-22	Taiho Pharmaceutical Co., Ltd.	抗腫瘍効果増強剤、抗腫瘍剤及び癌治療方法
EP1789427B1 (de)	2004-09-01	2009-05-20	Platco Technologies (Proprietary) Limited	Herstellung von platin(ii)-komplexen
US20060063833A1 (en) *	2004-09-22	2006-03-23	Edgar Schridde	Ready-to-use oxaliplatin solutions
US20060063720A1 (en) *	2004-09-22	2006-03-23	Edgar Schridde	Oxaliplatin solution concentrate
DE102004052877B4 (de) *	2004-11-02	2008-06-19	Ebewe Pharma Ges.M.B.H. Nfg.Kg	Stabile wässrige Formulierungen eines Platin-Derivats
JP2006248978A (ja) *	2005-03-10	2006-09-21	Mebiopharm Co Ltd	新規なリポソーム製剤
WO2007029268A2 (en)	2005-09-05	2007-03-15	Dabur Pharma Limited	Stable oxaliplatin formulation
CN101389637A (zh)	2006-01-30	2009-03-18	普拉托技术（私有）公司	铂(ⅱ)配合物的制备
CN101442998B (zh) *	2006-03-16	2012-03-14	比奥纽默里克药物公司	抗癌活性加强化合物和制剂及其用法
US20090317489A1 (en)	2006-05-09	2009-12-24	Hanspeter Nick	Combination Comprising an Iron Chelator and an Anti-Neoplastic Agent and Use Thereof
BRPI0806596A2 (pt) *	2007-01-18	2013-07-23	Merck Patent Ges Mit Berchraenkter Haftung	medicamento e terapia especÍfica usando-se ligantes de integrina para o tratamento de cÂncer
US20090076139A1 (en) *	2007-09-19	2009-03-19	Protia, Llc	Deuterium-enriched oxalplatin
EP2152239A1 (de) *	2007-11-12	2010-02-17	Intas Pharmaceuticals Limited	Stabile oxaliplatinzusammensetzung zur parenteralen verabreichung
AU2008352597B2 (en)	2008-03-14	2012-03-08	Bionumerik Pharmaceuticals, Inc.	Treatment methods and compositions for lung cancer, adenocarcinoma, and other medical conditions
JP5667886B2 (ja)	2008-03-14	2015-02-12	バイオニューメリック・ファーマスーティカルズ・インコーポレイテッド	癌患者の生存時間を増大させるための組成物及び化合物の使用方法
EP2481396A4 (de)	2009-09-21	2014-03-05	Jw Pharmaceutical Corp	Oxaliplatin-nanopartikel und herstellungsverfahren dafür
US20130096170A1 (en)	2011-10-14	2013-04-18	Hospira, Inc.	Methods of treating pediatric patients using dexmedetomidine
AU2013202575B1 (en) *	2012-01-04	2013-05-16	Hospira, Inc.	Dexmedetomidine premix formulation
US8242158B1 (en) *	2012-01-04	2012-08-14	Hospira, Inc.	Dexmedetomidine premix formulation
JP5314790B1 (ja) *	2012-07-09	2013-10-16	東和薬品株式会社	オキサリプラチン含有医薬組成物
EP2883542B1 (de)	2012-08-10	2019-05-01	Taiho Pharmaceutical Co., Ltd.	Stabile oxaliplatin-verkapselnde wässrige liposomdispersion und stabilisierungsverfahren dafür
MX2015003007A (es)	2012-09-07	2015-06-05	Coherus Biosciences Inc	Formulaciones acuosas estables de adalimumab.
CN103690494B (zh) *	2013-11-29	2015-04-15	杭州华东医药集团新药研究院有限公司	一种低杂质含有奥沙利铂的组合物及其制备方法
CA2953350C (en)	2014-06-23	2019-11-26	Placon Therapeutics, Inc.	Platinum compounds, compositions, and uses thereof
BR112018000254A2 (pt)	2015-07-07	2018-09-04	H Lundbeck As	inibidores de pde9 com cadeia principal de imidazotriazinona e cadeia principal de imidazopirazinona para o tratamento de doenças periféricas
CN104940151A (zh) *	2015-07-23	2015-09-30	青岛蓝盛洋医药生物科技有限责任公司	一种抗癌药物奥沙利铂冻干粉针剂组合物
US11229702B1 (en)	2015-10-28	2022-01-25	Coherus Biosciences, Inc.	High concentration formulations of adalimumab
WO2017184880A1 (en)	2016-04-20	2017-10-26	Coherus Biosciences, Inc.	A method of filling a container with no headspace
WO2017192290A1 (en)	2016-05-04	2017-11-09	The Wistar Institute Of Anatomy And Biology	Methods of treating cancers overexpressing carm1 with ezh2 inhibitors and platinum-based antineoplastic drugs
AU2017292650A1 (en)	2016-07-06	2018-12-13	H. Lundbeck A/S	PDE9 inhibitors for treatment of peripheral diseases
SI3630772T1 (sl)	2017-05-26	2024-05-31	Cardurion Pharmaceuticals, Inc.,	Postopki izdelave in uporabe zaviralcev pde9
EP3801526B1 (de)	2018-05-25	2023-12-27	Imara Inc.	Monohydrat und kristalline formen von 6-[(3s,4s)-4-methyl-1- (pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl- 7h-imid azo [1,5- a] pyrazin-8-on
CN112996512B (zh)	2018-08-31	2025-01-03	卡都瑞恩医药公司	用于治疗镰状细胞病的pde9抑制剂

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JPS6041077B2 (ja) *	1976-09-06	1985-09-13	喜徳喜谷	１，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
US4657927A (en) *	1978-05-04	1987-04-14	Research Corporation	Malonato platinum compounds
IL83380A (en) *	1987-07-30	1991-04-15	Teva Pharma	Stable aqueous cisplatin solutions
NL8901433A (nl) *	1989-06-06	1991-01-02	Pharmachemie Bv	Carboplatinpreparaat.
JPH04185601A (ja) *	1990-11-20	1992-07-02	Unitika Ltd	白金抗癌剤徐放性製剤
JP2673331B2 (ja)	1993-01-12	1997-11-05	田中貴金属工業株式会社	光学的に高純度なシス―オキザラート（トランス―１―１，２―シクロヘキサンジアミン）白金（▲ｉｉ▼）
WO1994012193A1 (fr) *	1992-11-24	1994-06-09	Debiopharm S.A.	Combinaison de cisplatine avec l'oxaliplatine
US5455270A (en) *	1993-08-11	1995-10-03	Bristol-Myers Squibb Co.	Stabilized solutions of platinum(II) antitumor agents
JP3547755B2 (ja)	1994-08-08	2004-07-28	デビオファーム・エス・アー	オキサリプラティヌムの医薬的に安定な製剤

1995
- 1995-08-07 JP JP50715996A patent/JP3547755B2/ja not_active Expired - Lifetime
- 1995-08-07 AT AT95925976T patent/ATE197249T1/de not_active IP Right Cessation
- 1995-08-07 CZ CZ1997379A patent/CZ286714B6/cs not_active IP Right Cessation
- 1995-08-07 CN CNB951944436A patent/CN1138541C/zh not_active Expired - Lifetime
- 1995-08-07 DE DE69519300T patent/DE69519300T2/de not_active Expired - Lifetime
- 1995-08-07 IL IL11485295A patent/IL114852A/xx not_active IP Right Cessation
- 1995-08-07 CA CA002196922A patent/CA2196922C/fr not_active Expired - Lifetime
- 1995-08-07 US US08/776,240 patent/US5716988A/en not_active Expired - Lifetime
- 1995-08-07 AU AU29896/95A patent/AU2989695A/en not_active Abandoned
- 1995-08-07 ES ES95925976T patent/ES2152412T3/es not_active Expired - Lifetime
- 1995-08-07 EP EP95925976A patent/EP0774963B1/de not_active Expired - Lifetime
- 1995-08-07 DK DK95925976T patent/DK0774963T3/da active
- 1995-08-07 BR BR9508554A patent/BR9508554A/pt not_active IP Right Cessation
- 1995-08-07 UA UA97010366A patent/UA42779C2/uk unknown
- 1995-08-07 WO PCT/IB1995/000614 patent/WO1996004904A1/fr not_active Ceased
- 1995-08-07 RU RU97104030A patent/RU2148400C1/ru not_active IP Right Cessation
- 1995-08-07 KR KR1019970700780A patent/KR100365171B1/ko not_active Ceased
1999
- 1999-03-31 AU AU22524/99A patent/AU731981B2/en not_active Expired

Also Published As

Publication number	Publication date
CA2196922A1 (fr)	1996-02-22
DE69519300T2 (de)	2001-05-31
KR970704434A (ko)	1997-09-06
RU2148400C1 (ru)	2000-05-10
IL114852A0 (en)	1995-12-08
CA2196922C (fr)	2004-06-01
UA42779C2 (uk)	2001-11-15
CN1154654A (zh)	1997-07-16
AU2989695A (en)	2000-03-07
ES2152412T3 (es)	2001-02-01
ATE197249T1 (de)	2000-11-15
CZ286714B6 (en)	2000-06-14
KR100365171B1 (ko)	2003-02-19
AU731981B2 (en)	2001-04-12
DE69519300D1 (de)	2000-12-07
EP0774963B1 (de)	2000-11-02
AU2252499A (en)	2000-03-23
CN1138541C (zh)	2004-02-18
WO1996004904A1 (fr)	1996-02-22
CZ37997A3 (en)	1997-06-11
US5716988A (en)	1998-02-10
EP0774963A1 (de)	1997-05-28
BR9508554A (pt)	1997-11-25
JP3547755B2 (ja)	2004-07-28
DK0774963T3 (da)	2001-01-29
JPH10508289A (ja)	1998-08-18

Legal Events

Date	Code	Title
2000-06-29	FF	Patent granted
2001-10-31	KB	Patent renewed
2005-11-20	KB	Patent renewed
2010-04-08	KB	Patent renewed
2013-07-31	KB	Patent renewed
2016-03-31	EXP	Patent expired

Publication	Publication Date	Title
IL114852A0 (en)	1995-12-08	A pharmaceutically stable preparation of oxaliplatinum
PL325825A1 (en)	1998-08-03	Microemulsion for use as a carrier for administering active compounds
IL150326A (en)	2005-06-19	Pediatric formula
MXPA02008654A (es)	2004-09-06	Formulaciones de ranolazina de liberacion prolongada.
RU94040387A (ru)	1996-10-20	Композиция, способствующая прекращению курения, никотиносодержащий распыляемый раствор, способ снижения потребности в курении табака, способ замены курения табака
NO20054324L (no)	2001-04-30	Anvendelse av ranolazin og minst ett pH-avhengig bindemiddel for fremstilling av ranolazinpreparater med depotvirkning
IL82209A0 (en)	1987-10-30	Insulin preparation
ZA912793B (en)	1992-12-30	Pharmaceutical formulations
MY114389A (en)	2002-10-31	Aqueous risperidone formulations
WO2002019999A3 (en)	2003-03-27	Compositions for treating sexual dysfunction, containing an no-donor and an antioxidant
GR3025742T3 (en)	1998-03-31	New pyrazine derivatives, their preparation and their use.
WO2000041504A3 (en)	2000-11-09	Use of tertbutylhydroquinone for lowering blood cholesterol and/or blood triblycerides
IL145187A0 (en)	2002-06-30	Echinocandin/carbohydrate complexes
ZA971134B (en)	1997-08-25	Multifunctional fat absorption and blood cholesterol reducing formulation.
DK1673074T3 (da)	2007-05-07	Flydende præparat, indeholdende tobramycin
EE04264B1 (et)	2004-04-15	Naatriumkloriidi kasutamine aine valmistamiseks kamptotetsiini derivaatide manustamisest tingitud gastrointestinaalsete kõrvaltoimete vähendamiseks
NZ507407A (en)	2002-08-28	Stable mitoxantrone solutions
CA2015632A1 (en)	1990-11-10	Stable solutions of rebeccamycin analog and preparations thereof
NZ334949A (en)	2000-12-22	Stabilised pharmaceutical composition of quinupristine and dalfopristine with methanesulphonic acid or hydrochloric acid
ZA988820B (en)	1999-04-06	Use of delta-aminolaevulinic acid for the preparation of a topical medicament for the integral diagnosis and/or therapy of tumours in hollow organs
PL350413A1 (en)	2002-12-02	Pharmaceutical effervescent formulation containing metamizol
Lin et al.	1997	Toxicity of a single oral dose of N-ethylphenylacetamide in rats
CA2120751A1 (en)	1993-04-15	Trimethoprim oral liquid
ES2125800A1 (es)	1999-03-01	Conjunto de infusion final.
ES2128966A1 (es)	1999-05-16	Composiciones farmaceuticas parenterales a base de calcitoninas sinteticas, de ph controlado, con bajo indice de dolor y buena estabilidad.