IL114948A - Transdermal therapeutic system containing estradiol and process for the preparation thereof - Google Patents

Transdermal therapeutic system containing estradiol and process for the preparation thereof

Info

Publication number: IL114948A
Authority: IL; Israel
Prior art keywords: therapeutic system; transdermal therapeutic; preparation; system containing; containing estradiol
Prior art date: 1994-08-20

Application number

IL11494895A

Other languages

English (en)

Other versions

IL114948A0 (en

Original Assignee

Lohmann Therapie Syst Lts

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-08-20

Filing date

1995-08-15

Publication date

2000-10-31

1995-08-15 Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts

1995-12-08 Publication of IL114948A0 publication Critical patent/IL114948A0/xx

2000-10-31 Publication of IL114948A publication Critical patent/IL114948A/xx

Links

230000001225 therapeutic effect Effects 0.000 title abstract 3
VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 title abstract 2
229930182833 estradiol Natural products 0.000 title abstract 2
229960005309 estradiol Drugs 0.000 title 1
239000013543 active substance Substances 0.000 abstract 4
239000000654 additive Substances 0.000 abstract 2
230000000996 additive effect Effects 0.000 abstract 2
239000011159 matrix material Substances 0.000 abstract 2
239000010410 layer Substances 0.000 abstract 1
239000011241 protective layer Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
General Chemical & Material Sciences (AREA)
Rheumatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Orthopedic Medicine & Surgery (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Steroid Compounds (AREA)
Traffic Control Systems (AREA)
Auxiliary Drives, Propulsion Controls, And Safety Devices (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IL11494895A 1994-08-20 1995-08-15 Transdermal therapeutic system containing estradiol and process for the preparation thereof IL114948A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4429664A DE4429664C2 (de)	1994-08-20	1994-08-20	Estradiol-TTS mit wasserbindenden Zusätzen und Verfahren zu seiner Herstellung

Publications (2)

Publication Number	Publication Date
IL114948A0 IL114948A0 (en)	1995-12-08
IL114948A true IL114948A (en)	2000-10-31

Family

ID=6526229

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11494895A IL114948A (en)	1994-08-20	1995-08-15	Transdermal therapeutic system containing estradiol and process for the preparation thereof

Country Status (21)

Country	Link
EP (1)	EP0776197B1 (fr)
JP (1)	JPH10504314A (fr)
KR (1)	KR100374476B1 (fr)
CN (1)	CN1073413C (fr)
AT (1)	ATE173163T1 (fr)
AU (1)	AU700119B2 (fr)
CA (1)	CA2197865C (fr)
CZ (1)	CZ50897A3 (fr)
DE (2)	DE4429664C2 (fr)
DK (1)	DK0776197T3 (fr)
ES (1)	ES2126308T3 (fr)
FI (1)	FI118721B (fr)
HU (1)	HUT77093A (fr)
IL (1)	IL114948A (fr)
NO (1)	NO970553L (fr)
NZ (1)	NZ291449A (fr)
PL (1)	PL180943B1 (fr)
SI (1)	SI0776197T1 (fr)
SK (1)	SK280299B6 (fr)
WO (1)	WO1996005815A1 (fr)
ZA (1)	ZA956926B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19600347A1 (de) *	1996-01-08	1997-07-10	Lohmann Therapie Syst Lts	Hauthaftende pharmazeutische Zubereitung, insbesondere TTS zur Abgabe von 17-beta-Estradiol an den menschlichen Organismus
US6623763B2 (en)	1996-01-08	2003-09-23	Lts Lohmann Therape-System Ag	Pharmaceutical preparation adhering to the skin, in particular a transdermal therapeutic system for the release of 17-β-estradiol to the human organism
GB9720470D0 (en)	1997-09-25	1997-11-26	Ethical Pharmaceuticals South	Inhibition of crystallization in transdermal devices
DE19827732A1 (de) *	1998-06-22	1999-12-23	Rottapharm Bv	Transdermales System vom Matrix-Typ zur Abgabe von Wirkstoffen mit einer hohen Abgaberate von Steroid-Hormonen und die Verwendung eines derartigen Systems zur Hormonersatztherapie

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU6712090A (en) *	1989-10-13	1991-05-16	Watson Laboratories, Inc.	Drug delivery systems and matrix therefor
DE4223360C1 (fr) *	1992-07-16	1993-04-08	Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
DE4237453C1 (fr) *	1992-11-06	1993-08-19	Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
DE4309830C1 (de) *	1993-03-26	1994-05-05	Lohmann Therapie Syst Lts	Wirkstoffpflaster für die Abgabe von Estradiol an die Haut

1994
- 1994-08-20 DE DE4429664A patent/DE4429664C2/de not_active Expired - Fee Related
1995
- 1995-08-12 SI SI9530203T patent/SI0776197T1/xx unknown
- 1995-08-12 AT AT95929104T patent/ATE173163T1/de active
- 1995-08-12 WO PCT/EP1995/003202 patent/WO1996005815A1/fr not_active Ceased
- 1995-08-12 DK DK95929104T patent/DK0776197T3/da active
- 1995-08-12 AU AU32583/95A patent/AU700119B2/en not_active Ceased
- 1995-08-12 NZ NZ291449A patent/NZ291449A/en unknown
- 1995-08-12 CA CA002197865A patent/CA2197865C/fr not_active Expired - Fee Related
- 1995-08-12 HU HU9701725A patent/HUT77093A/hu unknown
- 1995-08-12 CZ CZ97508A patent/CZ50897A3/cs unknown
- 1995-08-12 SK SK219-97A patent/SK280299B6/sk unknown
- 1995-08-12 EP EP95929104A patent/EP0776197B1/fr not_active Expired - Lifetime
- 1995-08-12 CN CN95194678A patent/CN1073413C/zh not_active Expired - Fee Related
- 1995-08-12 JP JP8507755A patent/JPH10504314A/ja active Pending
- 1995-08-12 DE DE59504233T patent/DE59504233D1/de not_active Expired - Lifetime
- 1995-08-12 ES ES95929104T patent/ES2126308T3/es not_active Expired - Lifetime
- 1995-08-12 KR KR1019970701107A patent/KR100374476B1/ko not_active Expired - Fee Related
- 1995-08-15 IL IL11494895A patent/IL114948A/xx not_active IP Right Cessation
- 1995-08-18 ZA ZA956926A patent/ZA956926B/xx unknown
1997
- 1997-02-06 NO NO970553A patent/NO970553L/no not_active Application Discontinuation
- 1997-02-18 PL PL95319014A patent/PL180943B1/pl unknown
- 1997-02-19 FI FI970702A patent/FI118721B/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU3258395A (en)	1996-03-14
AU700119B2 (en)	1998-12-24
EP0776197B1 (fr)	1998-11-11
FI970702A0 (fi)	1997-02-19
ZA956926B (en)	1996-03-25
IL114948A0 (en)	1995-12-08
PL319014A1 (en)	1997-07-21
SK280299B6 (sk)	1999-11-08
FI118721B (fi)	2008-02-29
DK0776197T3 (da)	1999-07-26
HUT77093A (hu)	1998-03-02
PL180943B1 (pl)	2001-05-31
DE59504233D1 (de)	1998-12-17
EP0776197A1 (fr)	1997-06-04
SI0776197T1 (en)	1999-04-30
KR970705380A (ko)	1997-10-09
NO970553D0 (no)	1997-02-06
ATE173163T1 (de)	1998-11-15
FI970702L (fi)	1997-02-19
NZ291449A (en)	1998-09-24
WO1996005815A1 (fr)	1996-02-29
CA2197865A1 (fr)	1996-02-29
MX9701301A (es)	1998-05-31
NO970553L (no)	1997-02-06
ES2126308T3 (es)	1999-03-16
SK21997A3 (en)	1997-07-09
CN1073413C (zh)	2001-10-24
CZ50897A3 (en)	1997-06-11
DE4429664A1 (de)	1996-02-22
JPH10504314A (ja)	1998-04-28
KR100374476B1 (ko)	2003-04-23
DE4429664C2 (de)	1997-09-11
CA2197865C (fr)	2005-10-25
CN1155836A (zh)	1997-07-30

Legal Events

Date	Code	Title
2001-03-19	FF	Patent granted
2001-07-24	KB	Patent renewed
2001-10-31	KB	Patent renewed
2005-11-20	KB	Patent renewed
2010-04-08	KB	Patent renewed
2014-03-31	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
CA2010218A1 (fr)	1990-08-18	Systeme therapeutique pour l'administration retardee et controlee a travers la peau ou les muqueuses de substances actives
IE800059L (en)	1980-07-11	Polymeric diffusion matrix
IL106512A (en)	1997-07-13	Plaster for the transdermal application of steroid hormones and process for the preparation thereof
HRP930991B1 (en)	2000-02-29	Transdermal therapeutic system containing the active substance 17-beta estradiol (anhydrous)
IL114948A0 (en)	1995-12-08	A transdermal therapeutic system containing estradiol and a process for the preparation thereof
MX9701302A (es)	1998-05-31	Sistema terapeutico transdermico de estradiol que comprende aditivos higroscopicos.
IL124538A0 (en)	1998-12-06	Transdermal delivery system for pharmaceutical compositions and a process for the preparation thereof
CA2197867A1 (fr)	1996-02-29	Systeme therapeutique transdermique renfermant de l'oestradiol et des additifs hydrophiles
IL125160A0 (en)	1999-01-26	A transdermal therapeutic composition a process for its preparation and use thereof