IL115199A - Composition comprising a polynucleic acid molecule in a liposome and method using said composition - Google Patents

Composition comprising a polynucleic acid molecule in a liposome and method using said composition

Info

Publication number
IL115199A
IL115199A IL11519995A IL11519995A IL115199A IL 115199 A IL115199 A IL 115199A IL 11519995 A IL11519995 A IL 11519995A IL 11519995 A IL11519995 A IL 11519995A IL 115199 A IL115199 A IL 115199A
Authority
IL
Israel
Prior art keywords
composition
liposome
polynucleic acid
acid molecule
vitro
Prior art date
Application number
IL11519995A
Other languages
English (en)
Other versions
IL115199A0 (en
Original Assignee
Opperbas Holding Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Opperbas Holding Bv filed Critical Opperbas Holding Bv
Priority to IL11519995A priority Critical patent/IL115199A/xx
Publication of IL115199A0 publication Critical patent/IL115199A0/xx
Priority to CA002231172A priority patent/CA2231172A1/en
Priority to AT96929504T priority patent/ATE219380T1/de
Priority to AU68884/96A priority patent/AU703271C/en
Priority to PCT/IL1996/000101 priority patent/WO1997010851A2/en
Priority to JP9512542A priority patent/JPH11514349A/ja
Priority to US09/029,376 priority patent/US6207456B1/en
Priority to EP96929504A priority patent/EP0879062B1/de
Priority to DE69621953T priority patent/DE69621953T2/de
Publication of IL115199A publication Critical patent/IL115199A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL11519995A 1995-09-07 1995-09-07 Composition comprising a polynucleic acid molecule in a liposome and method using said composition IL115199A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IL11519995A IL115199A (en) 1995-09-07 1995-09-07 Composition comprising a polynucleic acid molecule in a liposome and method using said composition
CA002231172A CA2231172A1 (en) 1995-09-07 1996-09-05 Nucleic acid delivery vehicle
AT96929504T ATE219380T1 (de) 1995-09-07 1996-09-05 Vehikel zum einbringen von nukleinsäuren in zellen
AU68884/96A AU703271C (en) 1995-09-07 1996-09-05 Nucleic acid delivery vehicle
PCT/IL1996/000101 WO1997010851A2 (en) 1995-09-07 1996-09-05 Nucleic acid delivery vehicle
JP9512542A JPH11514349A (ja) 1995-09-07 1996-09-05 核酸デリバリー担体
US09/029,376 US6207456B1 (en) 1995-09-07 1996-09-05 Nucleic acid delivery vehicle
EP96929504A EP0879062B1 (de) 1995-09-07 1996-09-05 Vehikel zum einbringen von nukleinsäuren in zellen
DE69621953T DE69621953T2 (de) 1995-09-07 1996-09-05 Vehikel zum einbringen von nukleinsäuren in zellen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL11519995A IL115199A (en) 1995-09-07 1995-09-07 Composition comprising a polynucleic acid molecule in a liposome and method using said composition

Publications (2)

Publication Number Publication Date
IL115199A0 IL115199A0 (en) 1995-12-31
IL115199A true IL115199A (en) 2005-05-17

Family

ID=11067956

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11519995A IL115199A (en) 1995-09-07 1995-09-07 Composition comprising a polynucleic acid molecule in a liposome and method using said composition

Country Status (8)

Country Link
US (1) US6207456B1 (de)
EP (1) EP0879062B1 (de)
JP (1) JPH11514349A (de)
AT (1) ATE219380T1 (de)
CA (1) CA2231172A1 (de)
DE (1) DE69621953T2 (de)
IL (1) IL115199A (de)
WO (1) WO1997010851A2 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6890555B1 (en) * 1992-02-05 2005-05-10 Qlt, Inc. Liposome compositions of porphyrin photosensitizers
DE19605548A1 (de) * 1996-02-15 1997-09-04 Boehringer Ingelheim Int Zusammensetzung für die Transfektion höherer eukaryotischer Zellen
FR2751222B1 (fr) * 1996-07-16 1998-10-09 Capsulis Compositions contenant au moins un acide nucleique et leurs applications dans le domaine biomedical, en particulier en therapie genique
DE19740092A1 (de) * 1997-09-12 1999-03-18 Ulrich Dr Med Hengge Liposomen und Verfahren zur Transfektion von Zellen
WO1999042091A2 (en) 1998-02-19 1999-08-26 Massachusetts Institute Of Technology Use of polycations as endosomolytic agents
US7276359B1 (en) * 1998-03-13 2007-10-02 Wyeth Polynucleotide composition, method of preparation, and use thereof
IL126681A0 (en) * 1998-10-21 1999-08-17 Opperbas Holding Bv Treatment of trauma-related conditions
US20040086558A1 (en) * 2001-02-22 2004-05-06 Moshe Baru Liposome mediated dna administration
CN1223602C (zh) * 2001-07-13 2005-10-19 一泰医药研究（深圳）有限公司 序列号11的生物活性肽
BR0210252A (pt) 2001-07-13 2004-09-14 Pepharm R & D Ltd Peptìdeos biologicamente ativos
CA2498918A1 (en) * 2002-10-09 2004-04-22 Pfizer Products Inc. Stabilized naked dna compositions
US20050042217A1 (en) * 2003-03-19 2005-02-24 Yan Qi Specific inhibition of allorejection
TWI353252B (en) 2004-04-28 2011-12-01 Cms Peptides Patent Holding Company Ltd Biologically active peptide vapeehptllteaplnpk der
CA2574802A1 (en) * 2004-07-20 2006-02-02 Isogenis, Inc. Specific inhibition of autoimmunity and diseases associated with autoantigens
NZ591825A (en) 2005-07-26 2012-10-26 Cms Peptides Patent Holding Company Ltd Biologically active peptides comprising PTTKTYFPHF and their uses in the manufacture of a medicament for modulating fatigue
US20070031512A1 (en) * 2005-08-03 2007-02-08 Amcol International Corporation Virus-interacting layered phyllosilicates and methods of inactivating viruses
US20100272769A1 (en) * 2005-08-03 2010-10-28 Amcol International Virus-, Bacteria-, and Fungi-Interacting Layered Phyllosilicates and Methods of Use
US20080184618A1 (en) * 2005-08-03 2008-08-07 Amcol International Virus-Interacting Layered Phyllosilicates and Methods of Use
CN101346393B (zh) 2005-11-02 2015-07-22 普洛体维生物治疗公司 修饰的siRNA分子及其应用
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
JPWO2008026781A1 (ja) * 2006-08-31 2010-01-21 直人 奥 逆標的化脂質小胞体
JP5484059B2 (ja) * 2006-10-06 2014-05-07 エスシーアイエル テクノロジー ゲゼルシャフト ミット ベシュレンクテル ハフツング 脊髄核インプラント
US8481084B2 (en) * 2007-05-23 2013-07-09 Amcol International Corporation Cholesterol-interacting layered phyllosilicates and methods of reducing hypercholesteremia in a mammal
ES2535419T3 (es) 2007-12-27 2015-05-11 Protiva Biotherapeutics Inc. Silenciamiento de expresión de quinasa tipo polo usando ARN interferente
EP2281041B1 (de) 2008-04-15 2014-07-02 Protiva Biotherapeutics Inc. Abdämpfen der csn5 genexpression unter verwendung von interferierender rns
WO2010033722A2 (en) 2008-09-17 2010-03-25 Isogenis, Inc. Construction of fully-deleted adenovirus-based gene delivery vectors and uses thereof
CA2802994A1 (en) 2010-06-17 2011-12-22 The United States Of America As Represented By The Secretary, National I Nstitutes Of Health Compositions and methods for treating inflammatory conditions
US10849975B2 (en) 2011-02-03 2020-12-01 Thomas Jefferson University Multivalent vaccines for rabies virus and filoviruses
AU2012340086A1 (en) 2011-11-17 2014-05-29 The Regents Of The University Of California Therapeutic RNA switches compositions and methods of use
US9035039B2 (en) 2011-12-22 2015-05-19 Protiva Biotherapeutics, Inc. Compositions and methods for silencing SMAD4
PL2897620T3 (pl) 2012-09-21 2020-11-02 Intensity Therapeutics, Inc Sposób leczenia nowotworu złośliwego
EP3201338B1 (de) 2014-10-02 2021-11-03 Arbutus Biopharma Corporation Zusammensetzungen und verfahren zur ausschaltung einer hepatitis-b-virus-genexpression
CN209264567U (zh) 2015-04-09 2019-08-16 必康达 使用荧光纳米金刚石的成像系统
WO2016197132A1 (en) 2015-06-04 2016-12-08 Protiva Biotherapeutics Inc. Treating hepatitis b virus infection using crispr
WO2017019891A2 (en) 2015-07-29 2017-02-02 Protiva Biotherapeutics, Inc. Compositions and methods for silencing hepatitis b virus gene expression
US12447166B2 (en) 2016-02-25 2025-10-21 Applied Biological Laboratories, Inc. Compositions and methods for protecting against airborne pathogens and irritants
EP3419629A4 (de) 2016-02-25 2019-10-30 Applied Biological Laboratories, Inc. Zusammensetzungen und verfahren zum schutz gegen luftbürtige pathogene und reizmittel
US11041170B2 (en) 2016-04-04 2021-06-22 Thomas Jefferson University Multivalent vaccines for rabies virus and coronaviruses
EP3500294A4 (de) 2016-08-22 2020-07-29 Arbutus Biopharma Corporation Anti-pd-1-antikörper oder fragmente davon zur behandlung von hepatitis b

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4789633A (en) * 1984-04-19 1988-12-06 University Of Tennessee Research Corporation Fused liposome and acid induced method for liposome fusion
US5283122A (en) 1984-04-19 1994-02-01 University Of Tennessee Research Corporation Fused liposome and acid induced method for liposome fusion
EP0452457B1 (de) * 1989-11-03 1997-08-20 Vanderbilt University Verfahren zur in vivo-verabreichung von funktionsfähigen fremden genen
NZ244306A (en) * 1991-09-30 1995-07-26 Boehringer Ingelheim Int Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation
US5928944A (en) * 1994-02-04 1999-07-27 The United States Of America As Represented By The Department Of Health And Human Services Method of adenoviral-medicated cell transfection

Also Published As

Publication number Publication date
WO1997010851A2 (en) 1997-03-27
EP0879062A2 (de) 1998-11-25
EP0879062B1 (de) 2002-06-19
AU703271B2 (en) 1999-03-25
IL115199A0 (en) 1995-12-31
DE69621953D1 (de) 2002-07-25
JPH11514349A (ja) 1999-12-07
AU6888496A (en) 1997-04-09
CA2231172A1 (en) 1997-03-27
DE69621953T2 (de) 2003-01-30
US6207456B1 (en) 2001-03-27
ATE219380T1 (de) 2002-07-15
WO1997010851A3 (en) 1997-06-05

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Legal Events

Date Code Title Description
MM9K Patent not in force due to non-payment of renewal fees