IL115882A - (3-Aminomethyloxazolyl- and thiazolyl) imidazo [1,5-a] benzo- (and thieno [2,3-f]) [1,4] diazepin-6-ones their manufacture and pharmaceutical compositions containing them - Google Patents

(3-Aminomethyloxazolyl- and thiazolyl) imidazo [1,5-a] benzo- (and thieno [2,3-f]) [1,4] diazepin-6-ones their manufacture and pharmaceutical compositions containing them

Info

Publication number
IL115882A
IL115882A IL11588295A IL11588295A IL115882A IL 115882 A IL115882 A IL 115882A IL 11588295 A IL11588295 A IL 11588295A IL 11588295 A IL11588295 A IL 11588295A IL 115882 A IL115882 A IL 115882A
Authority
IL
Israel
Prior art keywords
imidazo
dihydro
methyl
mol
benzodiazepin
Prior art date
Application number
IL11588295A
Other languages
English (en)
Other versions
IL115882A0 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL115882A0 publication Critical patent/IL115882A0/xx
Publication of IL115882A publication Critical patent/IL115882A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL11588295A 1994-11-11 1995-11-06 (3-Aminomethyloxazolyl- and thiazolyl) imidazo [1,5-a] benzo- (and thieno [2,3-f]) [1,4] diazepin-6-ones their manufacture and pharmaceutical compositions containing them IL115882A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH338694 1994-11-11
CH226195 1995-08-04

Publications (2)

Publication Number Publication Date
IL115882A0 IL115882A0 (en) 1996-01-31
IL115882A true IL115882A (en) 1998-10-30

Family

ID=25689945

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11588295A IL115882A (en) 1994-11-11 1995-11-06 (3-Aminomethyloxazolyl- and thiazolyl) imidazo [1,5-a] benzo- (and thieno [2,3-f]) [1,4] diazepin-6-ones their manufacture and pharmaceutical compositions containing them

Country Status (12)

Country Link
US (2) US5885986A (fr)
EP (1) EP0790999A1 (fr)
JP (1) JP2989013B2 (fr)
CN (1) CN1046519C (fr)
AU (1) AU3982695A (fr)
BR (1) BR9509711A (fr)
FI (1) FI971990L (fr)
IL (1) IL115882A (fr)
MA (1) MA23716A1 (fr)
MX (1) MX9703288A (fr)
TW (1) TW349100B (fr)
WO (1) WO1996015129A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2534639C (fr) * 2003-07-31 2013-07-30 Immunomedics, Inc. Anticorps anti-cd19
US20090054412A1 (en) * 2007-08-20 2009-02-26 John Alan Kemp Treatment of Sleep Disorders
KR101589314B1 (ko) 2007-08-20 2016-01-28 에보텍 인터내셔널 게엠베하 수면 장애의 치료
CN109790170B (zh) * 2016-08-16 2022-08-02 Uwm研究基金会有限公司 Gaba(a)受体调节剂和控制哮喘中气道高反应性和炎症的方法
CN111285878B (zh) * 2020-04-03 2022-05-13 杭州新博思生物医药有限公司 二氮杂卓类化合物及制法与其药用盐、前药和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1143728A (fr) * 1979-10-04 1983-03-29 Max Gerecke Derives d'imidazodiazepine
IL74070A (en) * 1984-01-19 1988-12-30 Hoffmann La Roche Imidazodiazepine derivatives,their manufacture and pharmaceutical compositions containing them
AU587802B2 (en) * 1985-03-08 1989-08-31 Ferrosan A/S Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds
US4771051A (en) * 1985-05-17 1988-09-13 A/S Ferrosan 3-substituted-4,5-dihydro-5-oxo imidazoquinazolines, their preparation, and their use in treating benzodiazepin receptor-related ailments
TW201311B (fr) * 1991-06-17 1993-03-01 Hoffmann La Roche
CA2143246C (fr) * 1994-03-16 2000-08-22 Thierry Godel Imidazodiazepines

Also Published As

Publication number Publication date
TW349100B (en) 1999-01-01
MA23716A1 (fr) 1996-07-01
MX9703288A (es) 1997-08-30
CN1046519C (zh) 1999-11-17
BR9509711A (pt) 1997-09-30
AU3982695A (en) 1996-06-06
JPH10505098A (ja) 1998-05-19
US5885986A (en) 1999-03-23
US5962450A (en) 1999-10-05
JP2989013B2 (ja) 1999-12-13
FI971990A0 (fi) 1997-05-09
WO1996015129A1 (fr) 1996-05-23
CN1167487A (zh) 1997-12-10
EP0790999A1 (fr) 1997-08-27
FI971990A7 (fi) 1997-05-09
FI971990L (fi) 1997-05-09
IL115882A0 (en) 1996-01-31

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees