IL115951A - Method for preparing opipramol - Google Patents

Method for preparing opipramol

Info

Publication number: IL115951A
Authority: IL; Israel
Prior art keywords: iminostilbene; opipramol; preparing; halopropyl; reacted
Prior art date: 1994-11-09

Application number

IL11595195A

Other languages

English (en)

Other versions

IL115951A0 (en

Inventor

Gutman Daniella

Ashkar Mishel

Original Assignee

Taro Pharma Ind

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-09

Filing date

1995-11-09

Publication date

1999-09-22

1995-11-09 Application filed by Taro Pharma Ind filed Critical Taro Pharma Ind

1996-01-31 Publication of IL115951A0 publication Critical patent/IL115951A0/xx

1999-09-22 Publication of IL115951A publication Critical patent/IL115951A/xx

Links

YNZFUWZUGRBMHL-UHFFFAOYSA-N 2-[4-[3-(11-benzo[b][1]benzazepinyl)propyl]-1-piperazinyl]ethanol Chemical compound C1CN(CCO)CCN1CCCN1C2=CC=CC=C2C=CC2=CC=CC=C21 YNZFUWZUGRBMHL-UHFFFAOYSA-N 0.000 title abstract 3
229960005290 opipramol Drugs 0.000 title abstract 3
LCGTWRLJTMHIQZ-UHFFFAOYSA-N 5H-dibenzo[b,f]azepine Chemical compound C1=CC2=CC=CC=C2NC2=CC=CC=C21 LCGTWRLJTMHIQZ-UHFFFAOYSA-N 0.000 abstract 5
WFCSWCVEJLETKA-UHFFFAOYSA-N 2-piperazin-1-ylethanol Chemical compound OCCN1CCNCC1 WFCSWCVEJLETKA-UHFFFAOYSA-N 0.000 abstract 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
MFESCIUQSIBMSM-UHFFFAOYSA-N I-BCP Chemical compound ClCCCBr MFESCIUQSIBMSM-UHFFFAOYSA-N 0.000 abstract 1
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical class OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 1
159000000021 acetate salts Chemical class 0.000 abstract 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
229910052794 bromium Chemical group 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
125000001309 chloro group Chemical group Cl* 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
YOGJPDTUEFXXDV-UHFFFAOYSA-N n-(3-bromopropyl)-6-(2-phenylethenyl)cyclohexa-2,4-dien-1-imine Chemical compound BrCCCN=C1C=CC=CC1C=CC1=CC=CC=C1 YOGJPDTUEFXXDV-UHFFFAOYSA-N 0.000 abstract 1
UIHFVNJKYJIELA-UHFFFAOYSA-N n-(3-chloropropyl)-6-(2-phenylethenyl)cyclohexa-2,4-dien-1-imine Chemical compound ClCCCN=C1C=CC=CC1C=CC1=CC=CC=C1 UIHFVNJKYJIELA-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
- C07D223/26—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a double bond between positions 10 and 11
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)

IL11595195A 1994-11-09 1995-11-09 Method for preparing opipramol IL115951A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/336,837 US5599929A (en)	1994-11-09	1994-11-09	Method for preparing opipramol

Publications (2)

Publication Number	Publication Date
IL115951A0 IL115951A0 (en)	1996-01-31
IL115951A true IL115951A (en)	1999-09-22

Family

ID=23317890

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11595195A IL115951A (en)	1994-11-09	1995-11-09	Method for preparing opipramol

Country Status (11)

Country	Link
US (1)	US5599929A (de)
EP (1)	EP0793652B1 (de)
CN (2)	CN1068312C (de)
AT (1)	ATE192439T1 (de)
AU (1)	AU4102296A (de)
CA (1)	CA2204261C (de)
DE (1)	DE69516715T2 (de)
HK (1)	HK1043793B (de)
IL (1)	IL115951A (de)
TR (1)	TR199501394A2 (de)
WO (1)	WO1996015113A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ITMI20030828A1 (it) *	2003-04-18	2004-10-19	Farchemia Srl	Procedimento per la preparazione dell'opipramolo.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2965639A (en) *		1960-12-20		New basically substituted azepine
CH364263A (de) *	1957-05-09	1962-09-15	Geigy Ag J R	Verfahren zur Herstellung von basisch substituierten Azepinen
FR1215599A (fr) *	1958-06-27	1960-04-19	Rhone Poulenc Sa	Nouveaux dérivés de l'iminodibenzyle substitués à l'azote par une chaîne pipérazinique et leur préparation
US3317515A (en) *	1964-05-06	1967-05-02	Upjohn Co	5-(2-aminooxyethyl)-10, 11-dihydro-5h-dibenz[b, f]azepines
US3668210A (en) *	1968-02-07	1972-06-06	Yoshitomi Pharmaceutical	3-chloro dihydrodibenzazepine derivatives
CH554342A (de) *	1969-06-20	1974-09-30	Takeda Chemical Industries Ltd	Verfahren zur herstellung neuer dibenzazepinderivate.

1994
- 1994-11-09 US US08/336,837 patent/US5599929A/en not_active Expired - Fee Related
1995
- 1995-11-09 AU AU41022/96A patent/AU4102296A/en not_active Abandoned
- 1995-11-09 DE DE69516715T patent/DE69516715T2/de not_active Expired - Fee Related
- 1995-11-09 AT AT95939059T patent/ATE192439T1/de not_active IP Right Cessation
- 1995-11-09 CN CN95196046A patent/CN1068312C/zh not_active Expired - Fee Related
- 1995-11-09 WO PCT/US1995/014320 patent/WO1996015113A1/en not_active Ceased
- 1995-11-09 CA CA002204261A patent/CA2204261C/en not_active Expired - Fee Related
- 1995-11-09 TR TR95/01394A patent/TR199501394A2/xx unknown
- 1995-11-09 IL IL11595195A patent/IL115951A/xx not_active IP Right Cessation
- 1995-11-09 EP EP95939059A patent/EP0793652B1/de not_active Expired - Lifetime
2000
- 2000-09-15 CN CN00128631A patent/CN1123567C/zh not_active Expired - Fee Related
2002
- 2002-07-23 HK HK02105420.7A patent/HK1043793B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2204261C (en)	2006-05-16
HK1043793B (zh)	2004-01-30
ATE192439T1 (de)	2000-05-15
CA2204261A1 (en)	1996-05-23
CN1123567C (zh)	2003-10-08
US5599929A (en)	1997-02-04
CN1068312C (zh)	2001-07-11
EP0793652A1 (de)	1997-09-10
AU4102296A (en)	1996-06-06
CN1162956A (zh)	1997-10-22
CN1332159A (zh)	2002-01-23
WO1996015113A1 (en)	1996-05-23
DE69516715T2 (de)	2001-02-01
TR199501394A2 (tr)	1996-06-21
DE69516715D1 (de)	2000-06-08
EP0793652B1 (de)	2000-05-03
HK1043793A1 (en)	2002-09-27
IL115951A0 (en)	1996-01-31

Legal Events

Date	Code	Title
2000-01-31	FF	Patent granted
2000-08-13	KB	Patent renewed
2002-02-10	KB	Patent renewed
2006-02-05	KB	Patent renewed
2010-11-30	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
ZA9610315B (en)	1997-06-17	Naphthyl-substituted benzimidazole derivates as anti-coagulants
PH31610A (en)	1998-11-03	Taxol derivatives.
AU553338B2 (en)	1986-07-10	Redox indicators
AU1079283A (en)	1983-08-18	A fungicidal indanylbenzamide
TW278071B (de)	1996-06-11
IL115951A0 (en)	1996-01-31	Improved method for preparing opipramol
AU4978690A (en)	1990-08-23	2-amino-7-hydroxytetralin carboxyalkyl ethers
HUT76689A (en)	1997-10-28	Process for the preparation of chiral intermediates useful for the synthesis of antifungal agents
IL133099A0 (en)	2001-03-19	Preparation of tri-iodo benzene compounds
ZA9419B (en)	1995-01-04	Preparation process for sulphurated derivatives of imidazole and the new intermediates obtained.
GR3032427T3 (en)	2000-05-31	An improved process for preparing side chain derivatives of cyclohexapeptidyl lipopeptides
IL136739A (en)	2005-06-19	Diol compounds and processes for their preparation
IE812498L (en)	1982-04-27	Pyrimidine derivatives.
CA1262904C (de)	1989-11-14
AU2001281806A1 (en)	2001-12-24	Method for preparing substituted 5-amino-n-phenyl-1,2,4-triazole-3-sulfonamides
TW257817B (en)	1995-09-21	Process of producing wetstrength agent
ES2017864A6 (es)	1991-03-01	Procedimiento para la preparacion de n-ciclopropilquinolonas.
IT1270834B (it)	1997-05-13	Disolfuro chinolico
ATE75468T1 (de)	1992-05-15	Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung.
ES2008825A6 (es)	1989-08-01	Procedimiento de preparacion de derivados de benzodiacepina -1,4 ona-2.