IL118196A - Pharmaceutical composition for inhibiting bone loss comprising 5-alpha-reductase inhibiting benzo¬f¾quinoline derivatives - Google Patents

Pharmaceutical composition for inhibiting bone loss comprising 5-alpha-reductase inhibiting benzo¬f¾quinoline derivatives

Info

Publication number
IL118196A
IL118196A IL11819696A IL11819696A IL118196A IL 118196 A IL118196 A IL 118196A IL 11819696 A IL11819696 A IL 11819696A IL 11819696 A IL11819696 A IL 11819696A IL 118196 A IL118196 A IL 118196A
Authority
IL
Israel
Prior art keywords
inhibiting
benzo
alpha
derivatives
pharmaceutical composition
Prior art date
Application number
IL11819696A
Other languages
English (en)
Other versions
IL118196A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL118196A0 publication Critical patent/IL118196A0/xx
Publication of IL118196A publication Critical patent/IL118196A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL11819696A 1995-05-10 1996-05-09 Pharmaceutical composition for inhibiting bone loss comprising 5-alpha-reductase inhibiting benzo¬f¾quinoline derivatives IL118196A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/438,420 US5550134A (en) 1995-05-10 1995-05-10 Methods for inhibiting bone loss

Publications (2)

Publication Number Publication Date
IL118196A0 IL118196A0 (en) 1996-09-12
IL118196A true IL118196A (en) 2000-06-29

Family

ID=23740592

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11819696A IL118196A (en) 1995-05-10 1996-05-09 Pharmaceutical composition for inhibiting bone loss comprising 5-alpha-reductase inhibiting benzo¬f¾quinoline derivatives

Country Status (10)

Country Link
US (2) US5550134A (fr)
EP (1) EP0742010A3 (fr)
JP (1) JPH11511739A (fr)
AU (1) AU5855796A (fr)
CA (1) CA2220034A1 (fr)
IL (1) IL118196A (fr)
MY (1) MY132322A (fr)
WO (1) WO1996035422A1 (fr)
YU (1) YU27296A (fr)
ZA (1) ZA963694B (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997048694A1 (fr) * 1996-06-20 1997-12-24 Board Of Regents, The University Of Texas System Composes et procedes d'obtention de preparations pharmacologiquement actives et leurs utilisations
CA2270433A1 (fr) * 1996-10-30 1998-05-07 Eli Lilly And Company Synthese de benzo¬f|quinolinones
US6111110A (en) * 1996-10-30 2000-08-29 Eli Lilly And Company Synthesis of benzo[f]quinolinones
EP0852137B1 (fr) * 1996-11-29 2005-08-10 Basf Aktiengesellschaft Compositions cosmétiques contenant un filtre UV-A photostable
US5945412A (en) * 1996-12-09 1999-08-31 Merck & Co., Inc. Methods and compositions for preventing and treating bone loss
WO1998025623A1 (fr) * 1996-12-09 1998-06-18 Merck & Co., Inc. Procedes et compositions destines a prevenir et a traiter la perte osseuse
GB2324726A (en) * 1997-05-01 1998-11-04 Merck & Co Inc Combination Therapy for the Treatment of Osteoporosis
SE9702401D0 (sv) 1997-06-19 1997-06-19 Astra Ab Pharmaceutical use
WO1999007682A1 (fr) * 1997-08-08 1999-02-18 Toyama Chemical Co., Ltd. Derives d'acide quinolonecarboxylique ou sels de ces derives
GB9717428D0 (en) * 1997-08-19 1997-10-22 Glaxo Group Ltd Pharmaceutical composition
US6096781A (en) * 1997-11-14 2000-08-01 Eli Lilly And Company 2-arylbenzo[B]thiophenes useful for the treatment of estrogen deprivation syndrome
KR100261139B1 (ko) * 1998-01-16 2000-08-01 황준수 신규한 알릴티오피리다진 유도체 및 그의 제조방법
EP1089990A1 (fr) * 1998-06-30 2001-04-11 Neurogen Corporation 1-(benzothiazol-2-yl)-4-(1-phenylmethyl)piperazines en tant que ligands specifiques du sous-type du recepteur de la dopamine
US6291463B1 (en) 1998-06-30 2001-09-18 Neurogen Corporation 1-(Benzothiazol-2-yl)-4-(1-phenylmethyl) piperazines: dopamine receptor subtype specific ligands
CA2338298A1 (fr) * 1998-07-29 2000-02-10 Merck & Co., Inc. Composes tricycliques
US20040033950A1 (en) 2000-09-26 2004-02-19 Hock Janet M. Method of increasing bone toughness and stiffness and reducing fractures
US6258826B1 (en) 1998-10-13 2001-07-10 Eli Lilly And Company Pharmaceutical formulations and applications thereof for the treatment of estrogen deprivation syndrome
WO2000078351A1 (fr) * 1999-06-18 2000-12-28 Mitsubishi Pharma Corporation Promoteurs de l'osteogenese
WO2001017562A1 (fr) * 1999-09-02 2001-03-15 Yamanouchi Pharmaceutical Co., Ltd. Agents promoteurs de l'osteogenese
US6756480B2 (en) * 2000-04-27 2004-06-29 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US20050124537A1 (en) * 2000-04-27 2005-06-09 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
DE60116520T2 (de) * 2000-10-10 2006-08-31 Microchips, Inc., Bedford Microchip-reservoir-vorrichtungen mit drahtloser übertragung von energie und daten
CA2462456C (fr) * 2001-10-03 2010-05-04 Merck & Co., Inc. Androstane 17-beta-carboxamides en tant que modulateurs de recepteurs d'androgenes
WO2003059293A2 (fr) 2002-01-15 2003-07-24 Merck & Co., Inc. 17-hydroxy-4-aza-androstan-3-ones utilisees comme modulateurs du recepteur d'androgenes
US7045652B2 (en) * 2002-07-03 2006-05-16 Pfizer Inc Processes for preparing substituted aryl boronic acids
AU2003278766A1 (en) * 2002-09-04 2004-03-29 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
GB0222516D0 (en) * 2002-09-27 2002-11-06 Karobio Ab Novel compounds
GB0319150D0 (en) * 2003-08-14 2003-09-17 Glaxo Group Ltd Novel compounds
CA2562132A1 (fr) * 2004-04-08 2005-10-27 Merck & Co., Inc. 17 beta-acetamide-4-azasteroides utilises en tant que modulateurs du recepteur des androgenes
US7556821B2 (en) 2004-05-13 2009-07-07 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
US20080076975A1 (en) * 2005-01-25 2008-03-27 Microchips, Inc. Method and implantable device with reservoir array for pre-clinical in vivo testing
WO2006081279A2 (fr) * 2005-01-25 2006-08-03 Microchips, Inc. Regulation de la liberation de medicament par la modification transitoire de microenvironnements locaux
EP3345607B1 (fr) 2006-12-29 2022-10-26 Ossifi-Mab LLC Procédés de modification de croissance osseuse par administration d'antagoniste ou d'agoniste sost ou wise

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351833A (en) * 1980-07-28 1982-09-28 Pfizer Inc. 9-Amino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof as analgesics and anti-emetics
US5239075A (en) * 1991-08-21 1993-08-24 Eli Lilly And Company Process for the preparation of benzo (f) quinolinones
US5578724A (en) * 1994-09-20 1996-11-26 Eli Lilly And Company Process for preparation of benzo[f]quinolinones
TW450809B (en) * 1995-03-21 2001-08-21 Lilly Co Eli Pharmaceutical compositions for preventing or treating prostatic cancer comprising benzoquinolin-3-one derivatives

Also Published As

Publication number Publication date
EP0742010A2 (fr) 1996-11-13
YU27296A (sh) 1999-07-28
WO1996035422A1 (fr) 1996-11-14
JPH11511739A (ja) 1999-10-12
EP0742010A3 (fr) 2000-10-11
MY132322A (en) 2007-10-31
CA2220034A1 (fr) 1996-11-14
US5670514A (en) 1997-09-23
IL118196A0 (en) 1996-09-12
US5550134A (en) 1996-08-27
ZA963694B (en) 1997-11-10
AU5855796A (en) 1996-11-29

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Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees