IL119744A - Use of 8,9-dehydroestrone for the preparation of antioxidant medicaments - Google Patents

Use of 8,9-dehydroestrone for the preparation of antioxidant medicaments

Info

Publication number: IL119744A
Authority: IL; Israel
Prior art keywords: dehydroestrone; medicaments; antioxidant; preparation; antioxidant medicaments
Prior art date: 1995-12-04

Application number

IL11974496A

Other languages

English (en)

Other versions

IL119744A0 (en

Original Assignee

American Home Prod

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-12-04

Filing date

1996-12-03

Publication date

2003-01-12

1996-12-03 Application filed by American Home Prod filed Critical American Home Prod

1997-03-18 Publication of IL119744A0 publication Critical patent/IL119744A0/xx

2003-01-12 Publication of IL119744A publication Critical patent/IL119744A/xx

Links

OUGSRCWSHMWPQE-WMZOPIPTSA-N (13s,14s)-3-hydroxy-13-methyl-7,11,12,14,15,16-hexahydro-6h-cyclopenta[a]phenanthren-17-one Chemical compound OC1=CC=C2C(CC[C@]3([C@H]4CCC3=O)C)=C4CCC2=C1 OUGSRCWSHMWPQE-WMZOPIPTSA-N 0.000 title 1
239000003963 antioxidant agent Substances 0.000 title 1
230000003078 antioxidant effect Effects 0.000 title 1
239000003814 drug Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Gastroenterology & Hepatology (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Neurology (AREA)
Virology (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Steroid Compounds (AREA)

IL11974496A 1995-12-04 1996-12-03 Use of 8,9-dehydroestrone for the preparation of antioxidant medicaments IL119744A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US793195P	1995-12-04	1995-12-04

Publications (2)

Publication Number	Publication Date
IL119744A0 IL119744A0 (en)	1997-03-18
IL119744A true IL119744A (en)	2003-01-12

Family

ID=21728885

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11974496A IL119744A (en)	1995-12-04	1996-12-03	Use of 8,9-dehydroestrone for the preparation of antioxidant medicaments

Country Status (22)

Country	Link
EP (1)	EP0778025B1 (cs)
JP (1)	JPH09169650A (cs)
KR (1)	KR100444002B1 (cs)
CN (1)	CN1104900C (cs)
AR (2)	AR005866A1 (cs)
AT (1)	ATE263565T1 (cs)
AU (1)	AU703814B2 (cs)
BR (1)	BR9605777A (cs)
CA (1)	CA2191835A1 (cs)
CZ (1)	CZ289780B6 (cs)
DE (1)	DE69632117T2 (cs)
DK (1)	DK0778025T3 (cs)
ES (1)	ES2215187T3 (cs)
HU (1)	HUP9603329A3 (cs)
IL (1)	IL119744A (cs)
MX (1)	MX9606009A (cs)
NO (1)	NO312654B1 (cs)
NZ (1)	NZ299858A (cs)
PT (1)	PT778025E (cs)
SI (1)	SI0778025T1 (cs)
SK (1)	SK154296A3 (cs)
ZA (1)	ZA969923B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19723794A1 (de) *	1997-06-06	1998-12-10	Jenapharm Gmbh	Nichtestrogene Derivate des Estradiols mit antioxidativer Aktivität
JP2002322081A (ja) *	2001-02-22	2002-11-08	Nonogawa Shoji Kk	生体の遺伝子損傷抑制剤
US7892751B2 (en)	2003-06-09	2011-02-22	Redox-Reactive Reagents Llc	Method of detecting or diagnosing of a neurodegenerative disease or condition
US9557325B2 (en)	2003-06-09	2017-01-31	Redox-Reactive Reagents Llc	Method of altering the binding specificity of proteins by oxidation-reduction reactions
AU2004248155B2 (en) *	2003-06-09	2008-10-23	Redox-Reactive Reagents L.L.C.	Method of altering the binding specificity of plasma proteins by oxidation-reduction reactions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5210081A (en) *	1992-02-26	1993-05-11	American Home Products Corporation	Alkali metal 8,9-dehydroestrone sulfate esters
DE4334823C2 (de) *	1993-10-09	1998-09-17	Schering Ag	Verfahren zur Herstellung von Schwefelsäurehalbestern von Estrogenen
US5395831A (en) *	1994-04-08	1995-03-07	American Home Products Corporation	Treating cardiac disorders with Δ9(11)-dehydro-8-isoestrone
DE19509729A1 (de) *	1995-03-13	1996-09-19	Schering Ag	17-Difluormethylen-Estratriene

1996
- 1996-11-25 AU AU71944/96A patent/AU703814B2/en not_active Ceased
- 1996-11-26 ZA ZA9609923A patent/ZA969923B/xx unknown
- 1996-11-27 AR ARP960105366A patent/AR005866A1/es not_active Application Discontinuation
- 1996-11-28 DK DK96308632T patent/DK0778025T3/da active
- 1996-11-28 EP EP96308632A patent/EP0778025B1/en not_active Expired - Lifetime
- 1996-11-28 SI SI9630674T patent/SI0778025T1/xx unknown
- 1996-11-28 AT AT96308632T patent/ATE263565T1/de not_active IP Right Cessation
- 1996-11-28 PT PT96308632T patent/PT778025E/pt unknown
- 1996-11-28 ES ES96308632T patent/ES2215187T3/es not_active Expired - Lifetime
- 1996-11-28 DE DE69632117T patent/DE69632117T2/de not_active Expired - Fee Related
- 1996-12-02 MX MX9606009A patent/MX9606009A/es not_active IP Right Cessation
- 1996-12-02 SK SK1542-96A patent/SK154296A3/sk unknown
- 1996-12-02 BR BR9605777A patent/BR9605777A/pt not_active Application Discontinuation
- 1996-12-02 CA CA002191835A patent/CA2191835A1/en not_active Abandoned
- 1996-12-02 NZ NZ299858A patent/NZ299858A/en unknown
- 1996-12-03 CZ CZ19963532A patent/CZ289780B6/cs not_active IP Right Cessation
- 1996-12-03 JP JP8322539A patent/JPH09169650A/ja not_active Ceased
- 1996-12-03 IL IL11974496A patent/IL119744A/xx not_active IP Right Cessation
- 1996-12-03 HU HU9603329A patent/HUP9603329A3/hu unknown
- 1996-12-03 NO NO19965165A patent/NO312654B1/no unknown
- 1996-12-03 KR KR1019960061345A patent/KR100444002B1/ko not_active Expired - Fee Related
- 1996-12-03 CN CN96123342A patent/CN1104900C/zh not_active Expired - Fee Related
2007
- 2007-03-19 AR ARP070101105A patent/AR059965A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
HUP9603329A2 (en)	1997-08-28
NO965165D0 (no)	1996-12-03
AU703814B2 (en)	1999-04-01
MX9606009A (es)	1997-08-30
DE69632117D1 (de)	2004-05-13
KR970032870A (ko)	1997-07-22
HU9603329D0 (en)	1997-01-28
SI0778025T1 (en)	2004-08-31
NO965165L (no)	1997-06-05
CN1158725A (zh)	1997-09-10
HUP9603329A3 (en)	1998-01-28
DK0778025T3 (da)	2004-06-07
AU7194496A (en)	1997-06-12
EP0778025A1 (en)	1997-06-11
ATE263565T1 (de)	2004-04-15
AR059965A2 (es)	2008-05-14
PT778025E (pt)	2004-08-31
CA2191835A1 (en)	1997-06-05
AR005866A1 (es)	1999-07-21
ZA969923B (en)	1998-05-26
BR9605777A (pt)	1998-08-25
EP0778025B1 (en)	2004-04-07
HK1010095A1 (en)	1999-06-11
CN1104900C (zh)	2003-04-09
KR100444002B1 (ko)	2004-11-03
CZ289780B6 (cs)	2002-04-17
IL119744A0 (en)	1997-03-18
NZ299858A (en)	2001-03-30
ES2215187T3 (es)	2004-10-01
SK154296A3 (en)	1997-08-06
JPH09169650A (ja)	1997-06-30
DE69632117T2 (de)	2004-08-26
CZ353296A3 (en)	1997-08-13
NO312654B1 (no)	2002-06-17

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Legal Events

Date	Code	Title
2003-07-06	FF	Patent granted
2003-07-31	KB	Patent renewed
2007-02-12	KB	Patent renewed
2011-07-31	MM9K	Patent not in force due to non-payment of renewal fees