IL121900A - שיטה לטיהור של אימונוגלובולינים - Google Patents

שיטה לטיהור של אימונוגלובולינים

Info

Publication number
IL121900A
IL121900A IL12190097A IL12190097A IL121900A IL 121900 A IL121900 A IL 121900A IL 12190097 A IL12190097 A IL 12190097A IL 12190097 A IL12190097 A IL 12190097A IL 121900 A IL121900 A IL 121900A
Authority
IL
Israel
Prior art keywords
column
solution
immunoglobulins
cation exchange
purification
Prior art date
Application number
IL12190097A
Other languages
English (en)
Other versions
IL121900A0 (en
Inventor
Israel Nur
Original Assignee
Omrix Biopharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omrix Biopharmaceuticals Ltd filed Critical Omrix Biopharmaceuticals Ltd
Priority to IL12190097A priority Critical patent/IL121900A/he
Publication of IL121900A0 publication Critical patent/IL121900A0/xx
Priority to AU94568/98A priority patent/AU9456898A/en
Priority to PCT/IL1998/000483 priority patent/WO1999018130A1/en
Publication of IL121900A publication Critical patent/IL121900A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL12190097A 1997-10-07 1997-10-07 שיטה לטיהור של אימונוגלובולינים IL121900A (he)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IL12190097A IL121900A (he) 1997-10-07 1997-10-07 שיטה לטיהור של אימונוגלובולינים
AU94568/98A AU9456898A (en) 1997-10-07 1998-10-02 A method for the purification of immunoglobulins
PCT/IL1998/000483 WO1999018130A1 (en) 1997-10-07 1998-10-02 A method for the purification of immunoglobulins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL12190097A IL121900A (he) 1997-10-07 1997-10-07 שיטה לטיהור של אימונוגלובולינים

Publications (2)

Publication Number Publication Date
IL121900A0 IL121900A0 (en) 1998-03-10
IL121900A true IL121900A (he) 2001-12-23

Family

ID=11070714

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12190097A IL121900A (he) 1997-10-07 1997-10-07 שיטה לטיהור של אימונוגלובולינים

Country Status (3)

Country Link
AU (1) AU9456898A (he)
IL (1) IL121900A (he)
WO (1) WO1999018130A1 (he)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8354249B2 (en) 2005-08-11 2013-01-15 Omrix Biopharmaceuticals Ltd. Intravenous immunoglobulin composition

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0001128D0 (sv) * 2000-03-30 2000-03-30 Amersham Pharm Biotech Ab A method of producing IgG
ES2184594B1 (es) 2001-01-17 2004-01-01 Probitas Pharma Sa Procedimiento para la produccion de gammaglobulina g humana inactivada de virus.
TW200716664A (en) * 2005-05-10 2007-05-01 Murray Goulburn Coop Co Ltd Immunoglobulin fraction and process therefor
TWI320788B (en) 2005-05-25 2010-02-21 Hoffmann La Roche Method for the purification of antibodies
US20070128693A1 (en) * 2005-12-06 2007-06-07 Advantek Serum Laboratories Limited3/F Method for the inactivation and removal of dengue virus from biological samples
SI2061803T2 (sl) 2006-08-28 2023-01-31 Ares Trading S.A. Postopek za čiščenje proteinov, ki vsebujejo FC
BRPI0920572A8 (pt) 2008-10-20 2015-10-27 Abbott Lab Inativação viral durante a purificação dos anticorpos
MX2011004199A (es) * 2008-10-20 2011-05-24 Abbott Lab Anticuerpos que unen a il-18 y metodos para purificar los mismos.
NZ592095A (en) 2008-10-20 2013-01-25 Abbott Lab Isolation and purification of il-12 and tnf-alpha antibodies using protein a affinity chromatography
EP2373341A1 (en) 2008-12-04 2011-10-12 Omrix Biopharmaceuticals Ltd. Subcutaneous administration of anti-hepatitis b antibodies
IL212911A0 (en) 2011-05-16 2011-07-31 Omrix Biopharmaceuticals Ltd Immunoglobulin reduced in thrombogenic contaminants and preparation thereof
CN112574296B (zh) * 2020-12-30 2023-05-19 中国医学科学院输血研究所 一种模拟IVIg的多人份混合人血浆IgG样品的分离纯化方法
FR3119246B1 (fr) 2021-01-27 2023-02-24 Centre Nat Rech Scient Procede de fabrication d'un detecteur des flux d'un premier et d'un deuxieme rayonnements ionisants

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3640513A1 (de) * 1986-11-27 1988-06-09 Biotest Pharma Gmbh Verfahren zur herstellung eines virussicheren, lagerstabilen und intravenoes vertraeglichen immunglobulin-g-praeparates
US5177194A (en) * 1990-02-01 1993-01-05 Baxter International, Inc. Process for purifying immune serum globulins
DE4118912C1 (he) * 1991-06-08 1992-07-02 Biotest Pharma Gmbh, 6072 Dreieich, De
DE4125625C2 (de) * 1991-08-02 1999-12-02 Octapharma Ag Glarus Verfahren zur Herstellung von virusinaktivierten Immunglobulinlösungen
US5429746A (en) * 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8354249B2 (en) 2005-08-11 2013-01-15 Omrix Biopharmaceuticals Ltd. Intravenous immunoglobulin composition
US9365635B2 (en) 2005-08-11 2016-06-14 Omrix Biopharmaceuticals Ltd. Intravenous immunoglobulin composition

Also Published As

Publication number Publication date
AU9456898A (en) 1999-04-27
IL121900A0 (en) 1998-03-10
WO1999018130A1 (en) 1999-04-15

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