IL122184A - Process for the hydrogenation of imines in the presence of hydrogen iodide using an iridium catalyst at elevated pressure - Google Patents
Process for the hydrogenation of imines in the presence of hydrogen iodide using an iridium catalyst at elevated pressureInfo
- Publication number
- IL122184A IL122184A IL12218496A IL12218496A IL122184A IL 122184 A IL122184 A IL 122184A IL 12218496 A IL12218496 A IL 12218496A IL 12218496 A IL12218496 A IL 12218496A IL 122184 A IL122184 A IL 122184A
- Authority
- IL
- Israel
- Prior art keywords
- imines
- hydrogenation
- elevated pressure
- hydrogen iodide
- iridium catalyst
- Prior art date
Links
- 239000003054 catalyst Substances 0.000 title 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 title 1
- 229910000043 hydrogen iodide Inorganic materials 0.000 title 1
- 238000005984 hydrogenation reaction Methods 0.000 title 1
- 150000002466 imines Chemical class 0.000 title 1
- 229910052741 iridium Inorganic materials 0.000 title 1
- GKOZUEZYRPOHIO-UHFFFAOYSA-N iridium atom Chemical compound [Ir] GKOZUEZYRPOHIO-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
- C07C209/52—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/88—Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH168595 | 1995-06-08 | ||
| PCT/EP1996/002419 WO1996041793A1 (en) | 1995-06-08 | 1996-06-04 | Process for the hydrogenation of imines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL122184A0 IL122184A0 (en) | 1998-04-05 |
| IL122184A true IL122184A (en) | 2000-02-29 |
Family
ID=4216210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12218496A IL122184A (en) | 1995-06-08 | 1996-06-04 | Process for the hydrogenation of imines in the presence of hydrogen iodide using an iridium catalyst at elevated pressure |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US5886225A (cs) |
| EP (1) | EP0830337B1 (cs) |
| JP (1) | JP4128623B2 (cs) |
| KR (1) | KR100470884B1 (cs) |
| CN (1) | CN1176900C (cs) |
| AR (1) | AR002359A1 (cs) |
| AT (1) | ATE187957T1 (cs) |
| AU (1) | AU710870B2 (cs) |
| BR (1) | BR9609159A (cs) |
| CA (1) | CA2220999C (cs) |
| CZ (1) | CZ287315B6 (cs) |
| DE (1) | DE69605794T2 (cs) |
| DK (1) | DK0830337T3 (cs) |
| EA (1) | EA000498B1 (cs) |
| ES (1) | ES2141512T3 (cs) |
| GR (1) | GR3032521T3 (cs) |
| HR (1) | HRP960253B1 (cs) |
| HU (1) | HU229337B1 (cs) |
| IL (1) | IL122184A (cs) |
| PL (1) | PL183317B1 (cs) |
| PT (1) | PT830337E (cs) |
| SK (1) | SK281568B6 (cs) |
| TW (1) | TW346482B (cs) |
| UA (1) | UA51652C2 (cs) |
| WO (1) | WO1996041793A1 (cs) |
| ZA (1) | ZA964832B (cs) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3833699B2 (ja) * | 1994-02-02 | 2006-10-18 | シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト | イミンの水素化法 |
| US6228971B1 (en) * | 1999-06-21 | 2001-05-08 | Ppg Industries Ohio, Inc. | Polymeric imine functional compositions and their use in film-forming compositions |
| US20070213540A1 (en) * | 2006-03-09 | 2007-09-13 | Degussa Ag | Process for the hydrogenation of imines |
| US8268872B2 (en) | 2008-02-22 | 2012-09-18 | Radius Health, Inc. | Selective androgen receptor modulators |
| CA2716320C (en) | 2008-02-22 | 2014-01-28 | Radius Health, Inc. | Selective androgen receptor modulators |
| AU2011212813B2 (en) | 2010-02-04 | 2014-10-23 | Radius Health, Inc. | Selective androgen receptor modulators |
| HUE030072T2 (en) | 2010-05-12 | 2017-04-28 | Radius Health Inc | Therapeutic prescriptions |
| US8642632B2 (en) | 2010-07-02 | 2014-02-04 | Radius Health, Inc. | Selective androgen receptor modulators |
| US9133182B2 (en) | 2010-09-28 | 2015-09-15 | Radius Health, Inc. | Selective androgen receptor modulators |
| CN102153589B (zh) | 2011-02-28 | 2013-01-02 | 大连多相触媒有限公司 | 一种亚胺的不对称加氢催化剂及其合成方法和应用 |
| EP2892877B1 (en) | 2012-09-06 | 2017-06-21 | Council of Scientific and Industrial Research | Process for the preparation of (s)-2-ethyl-n-(1-methoxypropan -2-yl)-6-methyl aniline |
| US9421264B2 (en) | 2014-03-28 | 2016-08-23 | Duke University | Method of treating cancer using selective estrogen receptor modulators |
| ES3055185T3 (en) | 2014-03-28 | 2026-02-10 | Univ Duke | Treatment of an estrogen receptor positive breast cancer using a selective estrogen receptor modulator |
| MX389702B (es) | 2016-06-22 | 2025-03-20 | Ellipses Pharma Ltd | Compuestos para usarse en el tratamiento de cancer de mama que expresa el receptor de androgenos (ar+). |
| JP7481115B2 (ja) | 2017-01-05 | 2024-05-10 | ラジウス ファーマシューティカルズ，インコーポレイテッド | Ｒａｄ１９０１－２ｈｃｌの多形性形態 |
| MX2020013713A (es) | 2018-07-04 | 2021-03-02 | Radius Pharmaceuticals Inc | Formas polimorficas de rad1901-2hcl. |
| EP3924328A1 (en) | 2019-02-12 | 2021-12-22 | Radius Pharmaceuticals, Inc. | Processes and compounds |
| CN110305025B (zh) * | 2019-07-23 | 2022-05-06 | 衢州学院 | 一种由亚胺催化氢化合成苄胺类化合物的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3772487D1 (de) * | 1986-08-04 | 1991-10-02 | Ciba Geigy Ag | Verfahren zur herstellung von optisch aktiven sekundaeren arylaminen. |
| US5011995A (en) * | 1987-07-28 | 1991-04-30 | Ciba-Geigy Corporation | Process for the preparation of optically active secondary amines |
| EP0419409B1 (de) * | 1989-09-18 | 1995-11-02 | Ciba-Geigy Ag | Iridiumkomplexe, Verfahren zu deren Herstellung und deren Verwendung |
| SG42936A1 (en) * | 1992-04-02 | 1997-10-17 | Ciba Geigy Ag | Ferrocenyl diphosphines as ligands for homogeneous catalysts |
| DK0741738T3 (da) * | 1994-02-02 | 2000-04-17 | Novartis Ag | Hydrogeneringskatallysator, fremgangsmåde til fremstilling deraf og hydrogeneringsfremgangsmåde |
-
1996
- 1996-04-06 UA UA97125857A patent/UA51652C2/uk unknown
- 1996-05-22 TW TW085106030A patent/TW346482B/zh not_active IP Right Cessation
- 1996-06-04 EA EA199700424A patent/EA000498B1/ru not_active IP Right Cessation
- 1996-06-04 DE DE69605794T patent/DE69605794T2/de not_active Expired - Lifetime
- 1996-06-04 SK SK1681-97A patent/SK281568B6/sk not_active IP Right Cessation
- 1996-06-04 WO PCT/EP1996/002419 patent/WO1996041793A1/en not_active Ceased
- 1996-06-04 DK DK96920786T patent/DK0830337T3/da active
- 1996-06-04 IL IL12218496A patent/IL122184A/xx not_active IP Right Cessation
- 1996-06-04 CN CNB96194661XA patent/CN1176900C/zh not_active Expired - Lifetime
- 1996-06-04 JP JP50257997A patent/JP4128623B2/ja not_active Expired - Lifetime
- 1996-06-04 ES ES96920786T patent/ES2141512T3/es not_active Expired - Lifetime
- 1996-06-04 PT PT96920786T patent/PT830337E/pt unknown
- 1996-06-04 HU HU9802307A patent/HU229337B1/hu unknown
- 1996-06-04 AT AT96920786T patent/ATE187957T1/de active
- 1996-06-04 CA CA002220999A patent/CA2220999C/en not_active Expired - Lifetime
- 1996-06-04 BR BR9609159A patent/BR9609159A/pt active IP Right Grant
- 1996-06-04 AU AU62218/96A patent/AU710870B2/en not_active Expired
- 1996-06-04 PL PL96323946A patent/PL183317B1/pl unknown
- 1996-06-04 US US08/973,575 patent/US5886225A/en not_active Expired - Lifetime
- 1996-06-04 CZ CZ19973919A patent/CZ287315B6/cs not_active IP Right Cessation
- 1996-06-04 KR KR1019970708383A patent/KR100470884B1/ko not_active Expired - Lifetime
- 1996-06-04 EP EP96920786A patent/EP0830337B1/en not_active Expired - Lifetime
- 1996-06-05 HR HR960253A patent/HRP960253B1/xx not_active IP Right Cessation
- 1996-06-06 AR ARP960102994A patent/AR002359A1/es active IP Right Grant
- 1996-06-07 ZA ZA964832A patent/ZA964832B/xx unknown
-
2000
- 2000-01-31 GR GR20000400217T patent/GR3032521T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| HP | Change in proprietorship | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |