IL122605A - Inhaler for dispensing powdered medical preparations - Google Patents
Inhaler for dispensing powdered medical preparationsInfo
- Publication number
- IL122605A IL122605A IL12260596A IL12260596A IL122605A IL 122605 A IL122605 A IL 122605A IL 12260596 A IL12260596 A IL 12260596A IL 12260596 A IL12260596 A IL 12260596A IL 122605 A IL122605 A IL 122605A
- Authority
- IL
- Israel
- Prior art keywords
- housing
- pressing
- plunger
- blister
- inhaler
- Prior art date
Links
- 239000003814 drug Substances 0.000 title claims abstract description 44
- 239000000843 powder Substances 0.000 title description 23
- 239000011888 foil Substances 0.000 claims abstract description 37
- 238000003825 pressing Methods 0.000 claims description 13
- 230000005540 biological transmission Effects 0.000 claims description 9
- 239000013013 elastic material Substances 0.000 claims description 2
- 239000000463 material Substances 0.000 description 9
- 239000011324 bead Substances 0.000 description 7
- 210000003811 finger Anatomy 0.000 description 6
- 229920000642 polymer Polymers 0.000 description 4
- -1 polypropylene Polymers 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- 230000000284 resting effect Effects 0.000 description 3
- 239000004698 Polyethylene Substances 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- XECAHXYUAAWDEL-UHFFFAOYSA-N acrylonitrile butadiene styrene Chemical compound C=CC=C.C=CC#N.C=CC1=CC=CC=C1 XECAHXYUAAWDEL-UHFFFAOYSA-N 0.000 description 2
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 2
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 2
- 239000004411 aluminium Substances 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 238000000071 blow moulding Methods 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 229920000915 polyvinyl chloride Polymers 0.000 description 2
- 239000004800 polyvinyl chloride Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 229910000838 Al alloy Inorganic materials 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 229930182556 Polyacetal Natural products 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 208000024716 acute asthma Diseases 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000013536 elastomeric material Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 238000002664 inhalation therapy Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 229920006324 polyoxymethylene Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000003856 thermoforming Methods 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 210000003813 thumb Anatomy 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0031—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up by bursting or breaking the package, i.e. without cutting or piercing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Packages (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Control And Other Processes For Unpacking Of Materials (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Basic Packing Technique (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19523516A DE19523516C1 (de) | 1995-06-30 | 1995-06-30 | Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen |
| PCT/EP1996/002384 WO1997002061A1 (en) | 1995-06-30 | 1996-06-01 | Inhaler for administering medicaments from blister packs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL122605A0 IL122605A0 (en) | 1998-08-16 |
| IL122605A true IL122605A (en) | 2001-07-24 |
Family
ID=7765485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12260596A IL122605A (en) | 1995-06-30 | 1996-06-01 | Inhaler for dispensing powdered medical preparations |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US5881719A (de) |
| EP (1) | EP0835148B1 (de) |
| JP (1) | JP3258025B2 (de) |
| KR (1) | KR100253855B1 (de) |
| CN (1) | CN1112222C (de) |
| AR (1) | AR002598A1 (de) |
| AT (1) | ATE205099T1 (de) |
| AU (1) | AU694667B2 (de) |
| BR (1) | BR9609645A (de) |
| CA (1) | CA2225999C (de) |
| CZ (1) | CZ286678B6 (de) |
| DE (2) | DE19523516C1 (de) |
| DK (1) | DK0835148T3 (de) |
| ES (1) | ES2163635T3 (de) |
| HR (1) | HRP960300B1 (de) |
| HU (1) | HU219905B (de) |
| IL (1) | IL122605A (de) |
| IN (1) | IN188127B (de) |
| NO (1) | NO314657B1 (de) |
| NZ (1) | NZ309793A (de) |
| PL (1) | PL181208B1 (de) |
| PT (1) | PT835148E (de) |
| RU (1) | RU2158609C2 (de) |
| SI (1) | SI9620082A (de) |
| SK (1) | SK282508B6 (de) |
| TR (1) | TR199701732T1 (de) |
| TW (1) | TW311092B (de) |
| UA (1) | UA34505C2 (de) |
| WO (1) | WO1997002061A1 (de) |
| ZA (1) | ZA965484B (de) |
Families Citing this family (159)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| CZ289029B6 (cs) * | 1994-09-21 | 2001-10-17 | Inhale Therapeutic Systems | Způsob aerosolizace práąku, zejména práąkového léku a zařízení k provádění tohoto způsobu |
| US20040237961A1 (en) * | 1995-06-08 | 2004-12-02 | Snow John Medlin | Inhalation actuated device for use with metered dose inhalers (MDIs) |
| US6672304B1 (en) | 1995-06-08 | 2004-01-06 | Innovative Devices, Llc | Inhalation actuated device for use with metered dose inhalers (MDIs) |
| US6209538B1 (en) * | 1995-08-02 | 2001-04-03 | Robert A. Casper | Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament |
| DE59605366D1 (de) | 1995-12-07 | 2000-07-06 | Jago Pharma Ag Muttenz | Inhalator zur mehrfachen dosisweisen abgabe eines pharmakologischen trockenpulvers |
| AU132977S (en) | 1996-05-17 | 1998-02-17 | Astrazeneca Ab | Container for inhaling apparatus |
| SE9700423D0 (sv) * | 1997-02-07 | 1997-02-07 | Astra Ab | Disposable inhaler |
| SE9700424D0 (sv) | 1997-02-07 | 1997-02-07 | Astra Ab | Powder inhaler |
| US6237590B1 (en) * | 1997-09-18 | 2001-05-29 | Delsys Pharmaceutical Corporation | Dry powder delivery system apparatus |
| USD421800S (en) * | 1998-02-19 | 2000-03-21 | Pierre Fabre Medicament | Powder and compressed-air inhaler |
| KR100277031B1 (ko) | 1998-02-25 | 2001-01-15 | 구본준 | 중첩 변조 방법 및 장치 |
| RO121834B1 (ro) | 1998-03-16 | 2008-06-30 | Inhale Therapeutic Systems, Inc. | Dispozitiv pentru administrarea unui agent activ |
| SE9800897D0 (sv) | 1998-03-17 | 1998-03-17 | Astra Ab | Inhalation device |
| HU224243B1 (hu) * | 1998-06-22 | 2005-06-28 | Astrazeneca Ab, | Készülék port tartalmazó, buborékcsomagolást képező fedőfóliával lezárt mélyedések ürítéséhez, szívás alkalmazásával |
| DE19831525A1 (de) * | 1998-07-14 | 2000-01-20 | Pfeiffer Erich Gmbh & Co Kg | Spender für Medien |
| UA73924C2 (en) * | 1998-10-09 | 2005-10-17 | Nektar Therapeutics | Device for delivering active agent formulation to lungs of human patient |
| DK1129064T3 (da) | 1998-11-12 | 2008-04-28 | Invitrogen Corp | Transfektionsreagenser |
| DE29908593U1 (de) | 1999-05-14 | 1999-07-22 | Jago Research AG, Hergiswil | Mundstück für einen Inhalator zur Abgabe eines Medikaments |
| MXPA01012533A (es) | 1999-06-05 | 2003-10-14 | Innovata Biomed Ltd | Sistema de suministro. |
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US6606992B1 (en) * | 1999-06-30 | 2003-08-19 | Nektar Therapeutics | Systems and methods for aerosolizing pharmaceutical formulations |
| US7305986B1 (en) | 1999-07-23 | 2007-12-11 | Mannkind Corporation | Unit dose capsules for use in a dry powder inhaler |
| US7464706B2 (en) * | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
| GB9920839D0 (en) * | 1999-09-04 | 1999-11-10 | Innovata Biomed Ltd | Inhaler |
| GB9928265D0 (en) * | 1999-12-01 | 2000-01-26 | Innovata Biomed Ltd | Inhaler |
| US6810872B1 (en) * | 1999-12-10 | 2004-11-02 | Unisia Jecs Corporation | Inhalant medicator |
| WO2001072605A1 (en) * | 2000-03-27 | 2001-10-04 | Dura Pharmaceuticals, Inc. | Containers for individual doses of an inhalable pharmaceutical |
| US7080644B2 (en) * | 2000-06-28 | 2006-07-25 | Microdose Technologies, Inc. | Packaging and delivery of pharmaceuticals and drugs |
| SE517227C2 (sv) * | 2000-09-25 | 2002-05-14 | Microdrug Ag | Inhalator för torrt pulver med folieskärare |
| US6443152B1 (en) | 2001-01-12 | 2002-09-03 | Becton Dickinson And Company | Medicament respiratory delivery device |
| US6644309B2 (en) | 2001-01-12 | 2003-11-11 | Becton, Dickinson And Company | Medicament respiratory delivery device and method |
| US6722364B2 (en) | 2001-01-12 | 2004-04-20 | Becton, Dickinson And Company | Medicament inhalation delivery devices and methods for using the same |
| EP1359902B1 (de) * | 2001-02-06 | 2007-08-08 | Innovata Biomed Limited | Bimodale trockenpulverzusammensetzung zur inhalation |
| FI20011317A0 (fi) * | 2001-06-20 | 2001-06-20 | Orion Corp | Jauheinhalaattori |
| US6681768B2 (en) | 2001-06-22 | 2004-01-27 | Sofotec Gmbh & Co. Kg | Powder formulation disintegrating system and method for dry powder inhalers |
| GB0120018D0 (en) * | 2001-08-16 | 2001-10-10 | Meridica Ltd | Pack containing medicament and dispensing device |
| CN1313171C (zh) * | 2001-09-19 | 2007-05-02 | 埃德文特药物有限公司 | 吸入器 |
| GB2380410B (en) * | 2001-10-05 | 2003-11-19 | Alchemy Healthcare Ltd | Apparatus for the nasal or oral delivery of a medicament |
| US7931022B2 (en) * | 2001-10-19 | 2011-04-26 | Respirks, Inc. | Method and apparatus for dispensing inhalator medicament |
| GB0128148D0 (en) | 2001-11-23 | 2002-01-16 | Innovata Biomed Ltd | Assembly |
| GB0130055D0 (en) * | 2001-12-14 | 2002-02-06 | Technology Innovation Ltd | Medicament packaging |
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| US7258118B2 (en) | 2002-01-24 | 2007-08-21 | Sofotec Gmbh & Co, Kg | Pharmaceutical powder cartridge, and inhaler equipped with same |
| DE10202940A1 (de) | 2002-01-24 | 2003-07-31 | Sofotec Gmbh & Co Kg | Patrone für einen Pulverinhalator |
| US6591832B1 (en) * | 2002-02-21 | 2003-07-15 | Saint-Gobain Calmar Inc. | Dry powder dispenser |
| US6923175B2 (en) | 2002-03-20 | 2005-08-02 | Mannkind Corporation | Inhalation apparatus |
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| US6932082B2 (en) | 2002-04-19 | 2005-08-23 | 3M Innovative Properties Company | Spacer or actuator for inertial removal of the non-respirable fraction of medicinal aerosols |
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| GB2398253B (en) * | 2003-02-11 | 2005-08-31 | Bespak Plc | Dispensing apparatus |
| GB2398503A (en) * | 2003-02-11 | 2004-08-25 | Bespak Plc | Inhaler with removable mouthpiece |
| WO2004082557A2 (en) * | 2003-03-15 | 2004-09-30 | Brin Tech International Limited | Package for and formulation of medicaments |
| US7559325B2 (en) † | 2003-04-09 | 2009-07-14 | Novartis Pharma Ag | Aerosolization apparatus with air inlet shield |
| HUE026950T2 (en) * | 2003-04-09 | 2016-08-29 | Novartis Ag | Nozzle with guide wire for puncturing the capsule |
| US8869794B1 (en) | 2003-04-09 | 2014-10-28 | Novartis Pharma Ag | Aerosolization apparatus with capsule puncturing member |
| EP1488819A1 (de) | 2003-06-16 | 2004-12-22 | Rijksuniversiteit te Groningen | Trockenpulverinhalator und Verfahren zur pulmonalen Inhalation von Trockenpulver |
| GB0320171D0 (en) | 2003-08-28 | 2003-10-01 | Optinose As | Delivery devices |
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| PT1616592E (pt) | 2004-07-16 | 2010-12-10 | Almirall Sa | Inalador para administração de fármacos em pó e um cartucho de pó para utilização com este inalador |
| ATE486064T1 (de) | 2004-08-20 | 2010-11-15 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
| KR20130066695A (ko) | 2004-08-23 | 2013-06-20 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
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| MX373000B (es) | 2005-09-14 | 2020-05-21 | Mannkind Corp | Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas. |
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| AR058289A1 (es) | 2005-12-12 | 2008-01-30 | Glaxo Group Ltd | Colector para ser usado en dispensador de medicamento |
| EP1986679B1 (de) | 2006-02-22 | 2017-10-25 | MannKind Corporation | Verfahren zur verbesserung der pharmazeutischen eigenschaften von mikropartikeln mit diketopiperazin und einem wirkstoff |
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| EP2063940B1 (de) | 2006-12-22 | 2012-01-11 | Almirall, S.A. | Inhalationsvorrichtung für arzneimittel in pulverform |
| US20080163610A1 (en) * | 2007-01-05 | 2008-07-10 | Matthew Thomas Baird | Method and system for regenerating exhaust system filtering and catalyst components using variable high engine idle |
| DE102007036411A1 (de) * | 2007-07-20 | 2009-02-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
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1995
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1996
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- 1996-06-01 UA UA98010496A patent/UA34505C2/uk unknown
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- 1996-06-01 WO PCT/EP1996/002384 patent/WO1997002061A1/en not_active Ceased
- 1996-06-01 HU HU9900116A patent/HU219905B/hu not_active IP Right Cessation
- 1996-06-01 DE DE69615033T patent/DE69615033T2/de not_active Expired - Lifetime
- 1996-06-01 PT PT96917488T patent/PT835148E/pt unknown
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- 1996-06-01 EP EP96917488A patent/EP0835148B1/de not_active Expired - Lifetime
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