IL125532A0 - Hematopoietic cell composition for use in transplantation - Google Patents

Hematopoietic cell composition for use in transplantation

Info

Publication number
IL125532A0
IL125532A0 IL12553298A IL12553298A IL125532A0 IL 125532 A0 IL125532 A0 IL 125532A0 IL 12553298 A IL12553298 A IL 12553298A IL 12553298 A IL12553298 A IL 12553298A IL 125532 A0 IL125532 A0 IL 125532A0
Authority
IL
Israel
Prior art keywords
transplantation
cell composition
hematopoietic cell
hematopoietic
composition
Prior art date
Application number
IL12553298A
Other languages
English (en)
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL12553298A priority Critical patent/IL125532A0/xx
Publication of IL125532A0 publication Critical patent/IL125532A0/xx
Priority to PCT/IL1999/000398 priority patent/WO2000006704A2/fr
Priority to US09/744,654 priority patent/US7101708B1/en
Priority to CA002336490A priority patent/CA2336490A1/fr
Priority to IL14100499A priority patent/IL141004A0/xx
Priority to EP99933100A priority patent/EP1100874A2/fr
Priority to AU49268/99A priority patent/AU4926899A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0093—Purging against cancer cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/21—Chemokines, e.g. MIP-1, MIP-2, RANTES, MCP, PF-4
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/59—Lectins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1394—Bone marrow stromal cells; whole marrow

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Environmental Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL12553298A 1998-07-27 1998-07-27 Hematopoietic cell composition for use in transplantation IL125532A0 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IL12553298A IL125532A0 (en) 1998-07-27 1998-07-27 Hematopoietic cell composition for use in transplantation
PCT/IL1999/000398 WO2000006704A2 (fr) 1998-07-27 1999-07-20 Composition a base de cellules hematopoietiques, a utiliser dans la transplantation
US09/744,654 US7101708B1 (en) 1998-07-27 1999-07-20 Hematopoietic cell composition for use in transplantation
CA002336490A CA2336490A1 (fr) 1998-07-27 1999-07-20 Composition a base de cellules hematopoietiques, a utiliser dans la transplantation
IL14100499A IL141004A0 (en) 1998-07-27 1999-07-20 Hematopoietic cell composition for use in transplantation
EP99933100A EP1100874A2 (fr) 1998-07-27 1999-07-20 Composition a base de cellules hematopoietiques, a utiliser dans la transplantation
AU49268/99A AU4926899A (en) 1998-07-27 1999-07-20 Hematopoietic cell composition for use in transplantation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL12553298A IL125532A0 (en) 1998-07-27 1998-07-27 Hematopoietic cell composition for use in transplantation

Publications (1)

Publication Number Publication Date
IL125532A0 true IL125532A0 (en) 1999-03-12

Family

ID=11071792

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12553298A IL125532A0 (en) 1998-07-27 1998-07-27 Hematopoietic cell composition for use in transplantation

Country Status (6)

Country Link
US (1) US7101708B1 (fr)
EP (1) EP1100874A2 (fr)
AU (1) AU4926899A (fr)
CA (1) CA2336490A1 (fr)
IL (1) IL125532A0 (fr)
WO (1) WO2000006704A2 (fr)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL146970A0 (en) * 2001-12-06 2002-08-14 Yeda Res & Dev Migration of haematopoietic stem cells and progenitor cells to the liver
US20050271639A1 (en) * 2002-08-22 2005-12-08 Penn Marc S Genetically engineered cells for therapeutic applications
WO2008121719A1 (fr) * 2007-03-30 2008-10-09 The Cleveland Clinic Foundation Procédé de traitement des troubles ischémiques
JPWO2004074463A1 (ja) * 2003-02-19 2006-06-01 学校法人早稲田大学 細胞分離用ハイドロゲルおよび細胞の分離方法
US20040191215A1 (en) * 2003-03-25 2004-09-30 Michael Froix Compositions for induction of a therapeutic response
EP1613742A2 (fr) 2003-04-08 2006-01-11 YEDA RESEARCH AND DEVELOPMENT Co. LTD. Cellules souches presentant une sensibilite accrue a un agent chimio-attractif, methodes de production et d'utilisation associees
US7332334B2 (en) 2003-04-18 2008-02-19 Oklahoma Medical Research Foundation Hematopoietic stem cells treated by in vitro fucosylation and methods of use
CA2525909A1 (fr) * 2003-05-16 2004-11-25 Kyowa Hakko Kogyo Co., Ltd. Nouvelle cellule souche derivee d'une tissu adulte et son utilisation
EP1670414A4 (fr) * 2003-10-06 2007-09-26 Cedars Sinai Medical Center Utilisation de l'expression de la proteine cxcr4 sur la surface de cellules souches en tant que marqueur de potentiel tropique de tumoral
KR20070085288A (ko) * 2004-09-24 2007-08-27 안지오블라스트 시스템스 인코퍼레이티드 간엽 전구세포의 증식 및/또는 생존성 증강 방법
EP1951864B1 (fr) 2005-11-07 2014-05-07 Amorcyte, Inc. Compositions et procedes de reparation de lesions vasculaires
US20110076255A1 (en) 2005-11-07 2011-03-31 Pecora Andrew L Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency
US8637005B2 (en) 2005-11-07 2014-01-28 Amorcyte, Inc. Compositions and methods of vascular injury repair
US9096831B2 (en) * 2006-05-19 2015-08-04 Versitech Limited Methods to enhance cell migration and engraftment
JP5416895B2 (ja) * 2007-10-23 2014-02-12 学校法人慶應義塾 単球由来多能性細胞（ｍｏｍｃ）の効率的な作製法
CA2709398C (fr) 2007-12-14 2017-11-07 The Cleveland Clinic Foundation Utilisation du facteur 1 derive de cellules stromales afin de favoriser la guerison des plaies
US20100125265A1 (en) * 2008-11-20 2010-05-20 Medtronic Vascular, Inc. Cell Delivery System to Induce Cell Growth and Angiogenesis
RU2497532C2 (ru) * 2008-12-03 2013-11-10 Эморсайт, Инк. Композиции, улучшающие перфузию в области инфаркта и способы восстановления сосудистого повреждения
US20150335400A1 (en) * 2009-06-17 2015-11-26 The Trustees Of Columbia University In The City Of New York Tooth scaffolds
WO2010148229A1 (fr) * 2009-06-17 2010-12-23 The Trustees Of Columbia University In The City Of New York Échafaudages dentaires
WO2011026041A2 (fr) 2009-08-28 2011-03-03 The Cleveland Clinic Foundation Administration de sdf-1 en vue du traitement de tissus ischémiques
EP2521565A1 (fr) * 2010-01-08 2012-11-14 Baxter International Inc Biomatrices pour attirer et retenir des cellules régénératrices et réparatrices
WO2012025925A1 (fr) * 2010-08-24 2012-03-01 Rappaport Family Institute For Research In The Medical Sciences Procédés d'amélioration de la transplantation en utilisant des sdf-1alpha
WO2012048276A2 (fr) 2010-10-08 2012-04-12 Caridianbct, Inc. Procédés et systèmes configurables pour la culture et la récolte de cellules dans un système de bioréacteur à fibres creuses
JP6220791B2 (ja) * 2011-12-02 2017-10-25 フェイト セラピューティクス，インコーポレイテッド 増強された幹細胞組成物
WO2015073913A1 (fr) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expansion de cellules dans un bioréacteur
WO2015148704A1 (fr) 2014-03-25 2015-10-01 Terumo Bct, Inc. Remplacement passif de milieu
EP3198006B1 (fr) 2014-09-26 2021-03-24 Terumo BCT, Inc. Alimentation programmée
WO2017004592A1 (fr) 2015-07-02 2017-01-05 Terumo Bct, Inc. Croissance cellulaire à l'aide de stimuli mécaniques
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
CN117247899A (zh) 2017-03-31 2023-12-19 泰尔茂比司特公司 细胞扩增
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
EP4314244B1 (fr) 2021-03-23 2025-07-23 Terumo BCT, Inc. Capture et multiplication cellulaire
US12209689B2 (en) 2022-02-28 2025-01-28 Terumo Kabushiki Kaisha Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device
CN115927169B (zh) * 2022-10-11 2023-08-11 再造再生医学科技(杭州)有限公司 用于扩增cd34+造血干细胞的培养液和体外扩增cd34+造血干细胞的方法

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DE4240635C2 (de) * 1992-12-03 1997-07-10 Lothar Prof Dr Kanz Vermehrung hämatopoetischer Vorläuferzellen ex vivo sowieZusammensetzungen hämatopoetischer Wachstumsfaktoren
US5665350A (en) * 1994-11-23 1997-09-09 University Of Massachusetts Medical Center Cell cycle dependent transplantation and ex vivo gene therapy

Also Published As

Publication number Publication date
US7101708B1 (en) 2006-09-05
CA2336490A1 (fr) 2000-02-10
WO2000006704A3 (fr) 2000-03-16
WO2000006704A2 (fr) 2000-02-10
EP1100874A2 (fr) 2001-05-23
AU4926899A (en) 2000-02-21

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