IL128264A0 - Process for the production of alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril - Google Patents

Process for the production of alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril

Info

Publication number: IL128264A0
Authority: IL; Israel
Prior art keywords: alkoxycarbonyldipeptides; lisinopril; intermediates; synthesis; production
Prior art date: 1998-02-09

Application number

IL12826499A

Other languages

English (en)

Original Assignee

Pfc Italiana Srl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-02-09

Filing date

1999-01-28

Publication date

2000-02-17

1999-01-28 Application filed by Pfc Italiana Srl filed Critical Pfc Italiana Srl

2000-02-17 Publication of IL128264A0 publication Critical patent/IL128264A0/xx

Links

108010007859 Lisinopril Proteins 0.000 title 1
230000015572 biosynthetic process Effects 0.000 title 1
239000000543 intermediate Substances 0.000 title 1
RLAWWYSOJDYHDC-BZSNNMDCSA-N lisinopril Chemical compound C([C@H](N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(O)=O)C(O)=O)CC1=CC=CC=C1 RLAWWYSOJDYHDC-BZSNNMDCSA-N 0.000 title 1
229960002394 lisinopril Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/064—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for omega-amino or -guanidino functions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Analytical Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL12826499A 1998-02-09 1999-01-28 Process for the production of alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril IL128264A0 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT98BO000063A IT1299341B1 (it)	1998-02-09	1998-02-09	Processo per la produzione di alcossicarbonildipeptidi intermedi nella sintesi del lisinopril.

Publications (1)

Publication Number	Publication Date
IL128264A0 true IL128264A0 (en)	2000-02-17

Family

ID=11342848

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12826499A IL128264A0 (en)	1998-02-09	1999-01-28	Process for the production of alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril

Country Status (10)

Country	Link
US (2)	US6031112A (it)
EP (1)	EP0943621A3 (it)
JP (1)	JPH11269196A (it)
BR (1)	BR9900439A (it)
CA (1)	CA2260450A1 (it)
HU (1)	HUP9900153A3 (it)
IL (1)	IL128264A0 (it)
IT (1)	IT1299341B1 (it)
TR (1)	TR199900247A3 (it)
ZA (1)	ZA99534B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1307265B1 (it) *	1999-08-09	2001-10-30	P F C Italiana Srl Speciality	Procedimento per la preparazione di prodotti intermedi nella sintesidi lisinopril.
IT1318623B1 (it) *	2000-07-13	2003-08-27	Isagro Ricerca Srl	Procedimento per la preparazione di derivati dipeptidici.
US6627760B1 (en)	2001-06-25	2003-09-30	Astrazeneca Ab	Amorphous compound
US6462174B1 (en)	2001-06-25	2002-10-08	Astrazeneca Ab	Amorphous compound
US6458769B1 (en)	2001-06-25	2002-10-01	Astrazeneca Ab	Amorphous compound
FR2916444B1 (fr) *	2007-05-25	2011-02-11	Sanofi Aventis	Procede de preparation de n-carboxyanhydride enantiomeriquement enrichi.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1290141A (it) *	1968-05-31	1972-09-20
IL58849A (en) *	1978-12-11	1983-03-31	Merck & Co Inc	Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
EP0168769A3 (en) *	1984-07-16	1989-02-08	Merck & Co. Inc.	Process for preparing carboxyalkyl dipeptides
JPH01254651A (ja) *	1988-04-04	1989-10-11	Kanegafuchi Chem Ind Co Ltd	Ｎ↑２−（１−カルボキシ−３−フエニルプロピル）−ｌ−リジン誘導体及び該化合物を用いるリジノプリルの製造法
SI9200213A (en) *	1992-09-16	1994-03-31	Krka	Process for preparing alkyl-l-alanil-l-proline derivates

1998
- 1998-02-09 IT IT98BO000063A patent/IT1299341B1/it active IP Right Grant
1999
- 1999-01-19 EP EP99101015A patent/EP0943621A3/en not_active Withdrawn
- 1999-01-20 HU HU9900153A patent/HUP9900153A3/hu unknown
- 1999-01-25 ZA ZA9900534A patent/ZA99534B/xx unknown
- 1999-01-25 US US09/237,071 patent/US6031112A/en not_active Expired - Fee Related
- 1999-01-27 CA CA002260450A patent/CA2260450A1/en not_active Abandoned
- 1999-01-28 IL IL12826499A patent/IL128264A0/xx unknown
- 1999-02-05 TR TR1999/00247A patent/TR199900247A3/tr unknown
- 1999-02-08 BR BR9900439-9A patent/BR9900439A/pt not_active Application Discontinuation
- 1999-02-08 JP JP11030618A patent/JPH11269196A/ja active Pending
- 1999-06-18 US US09/335,811 patent/US6166217A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2260450A1 (en)	1999-08-09
JPH11269196A (ja)	1999-10-05
US6031112A (en)	2000-02-29
HU9900153D0 (en)	1999-03-29
TR199900247A2 (xx)	2001-02-21
ITBO980063A1 (it)	1999-08-09
TR199900247A3 (tr)	2001-02-21
BR9900439A (pt)	2000-05-09
IT1299341B1 (it)	2000-03-16
US6166217A (en)	2000-12-26
EP0943621A3 (en)	2001-12-12
HUP9900153A2 (hu)	1999-11-29
EP0943621A2 (en)	1999-09-22
ZA99534B (en)	1999-07-26
ITBO980063A0 (it)	1998-02-09
HUP9900153A3 (en)	2002-02-28

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