IL129267A - Pharmaceutical compositions comprising histamine and/or serotonin for treatment of urinary incontinence - Google Patents
Pharmaceutical compositions comprising histamine and/or serotonin for treatment of urinary incontinenceInfo
- Publication number
- IL129267A IL129267A IL12926797A IL12926797A IL129267A IL 129267 A IL129267 A IL 129267A IL 12926797 A IL12926797 A IL 12926797A IL 12926797 A IL12926797 A IL 12926797A IL 129267 A IL129267 A IL 129267A
- Authority
- IL
- Israel
- Prior art keywords
- urinary incontinence
- serotonin
- histamine
- treatment
- pharmaceutical compositions
- Prior art date
Links
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 title abstract 4
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 title abstract 4
- 206010046543 Urinary incontinence Diseases 0.000 title abstract 3
- 229960001340 histamine Drugs 0.000 title abstract 2
- 229940076279 serotonin Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/417—Imidazole-alkylamines, e.g. histamine, phentolamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/731,702 US5877198A (en) | 1996-10-17 | 1996-10-17 | Treatment of urinary incontinence |
| PCT/US1997/018601 WO1998016225A1 (en) | 1996-10-17 | 1997-10-16 | Treatment of urinary incontinence and compositions for use therein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL129267A0 IL129267A0 (en) | 2000-02-17 |
| IL129267A true IL129267A (en) | 2003-10-31 |
Family
ID=24940633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12926797A IL129267A (en) | 1996-10-17 | 1997-10-16 | Pharmaceutical compositions comprising histamine and/or serotonin for treatment of urinary incontinence |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5877198A (de) |
| EP (1) | EP0946174B1 (de) |
| JP (1) | JP2001502336A (de) |
| AT (1) | ATE271867T1 (de) |
| AU (1) | AU729675B2 (de) |
| CA (1) | CA2269031C (de) |
| DE (1) | DE69730045T2 (de) |
| IL (1) | IL129267A (de) |
| WO (1) | WO1998016225A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA977967B (en) * | 1996-09-23 | 1999-03-04 | Lilly Co Eli | Combination therapy for treatment of psychoses |
| US6156780A (en) * | 1996-10-17 | 2000-12-05 | Milkhaus Laboratory, Inc. | Treatment of fecal incontinence |
| US20140121256A1 (en) * | 2012-10-26 | 2014-05-01 | Beech Tree Labs, Inc. | Method of treating muscular weakness comprising administering a composition comprising an effective amount of histamine and/or serotonin |
| US11564958B2 (en) | 2017-12-21 | 2023-01-31 | Resolys Bio, Inc. | Compositions and methods of treatment of Ehlers-Danlos syndromes |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4970071A (en) * | 1985-01-18 | 1990-11-13 | Mcmichael John | Immunotherapeutic methods and compositions employing antigens characteristic of non human malignant neoplasms |
| US4692332A (en) * | 1985-01-18 | 1987-09-08 | Mcmichael John | Immunotherapeutic methods and compositions employing antigens characteristic of malignant neoplasms |
| US4880626A (en) * | 1985-01-18 | 1989-11-14 | Mcmichael John | Immunotherapeutic methods and compositions for the treatment of diseases of viral origin, including acquired immune deficiency syndrome |
| US4689222A (en) * | 1985-01-18 | 1987-08-25 | Mcmichael John | Methods and materials for alleviation of pain symptoms of malignant neoplasia |
| US4966753A (en) * | 1987-08-18 | 1990-10-30 | Molecular Rx, Inc. | Immunotherapeutic methods and compositions employing antigens characteristic of malignant neoplasms |
| AU2485988A (en) * | 1987-09-10 | 1989-04-17 | John Mcmichael | Method and composition for enhancing animal fertility |
| JP2980677B2 (ja) * | 1990-04-27 | 1999-11-22 | マクマイケル，ジョン | 不正常なアミロイドβタンパク質と関連する中枢神経系疾患状態の治療のための方法および組成物 |
| ATE202940T1 (de) * | 1994-05-25 | 2001-07-15 | John Mcmichael | Mittel und methoden zur behandlung von plaque- krankheiten |
| FR2732017B1 (fr) * | 1995-03-21 | 2000-09-22 | Inst Nat Sante Rech Med | Nouveaux derives de l'imidazole antagonistes et/ou agonistes du recepteur h3 de l'histamine, leur preparation et leurs applications therapeutiques |
| DE69617856T2 (de) * | 1995-04-13 | 2002-06-27 | Milkhaus Laboratory, Inc. | Methoden zur behandlung von atemwegserkrankungen |
| US5610174A (en) * | 1995-06-02 | 1997-03-11 | Synaptic Pharmaceutical Corporation | Use of α1A -selective adrenoceptor agonists for the treatment of urinary incontinence |
-
1996
- 1996-10-17 US US08/731,702 patent/US5877198A/en not_active Expired - Lifetime
-
1997
- 1997-10-16 WO PCT/US1997/018601 patent/WO1998016225A1/en not_active Ceased
- 1997-10-16 IL IL12926797A patent/IL129267A/xx not_active IP Right Cessation
- 1997-10-16 AT AT97910115T patent/ATE271867T1/de not_active IP Right Cessation
- 1997-10-16 DE DE69730045T patent/DE69730045T2/de not_active Expired - Lifetime
- 1997-10-16 AU AU47572/97A patent/AU729675B2/en not_active Ceased
- 1997-10-16 CA CA002269031A patent/CA2269031C/en not_active Expired - Fee Related
- 1997-10-16 EP EP97910115A patent/EP0946174B1/de not_active Expired - Lifetime
- 1997-10-16 JP JP10518563A patent/JP2001502336A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2269031C (en) | 2003-09-09 |
| DE69730045D1 (de) | 2004-09-02 |
| AU729675B2 (en) | 2001-02-08 |
| EP0946174B1 (de) | 2004-07-28 |
| CA2269031A1 (en) | 1998-04-23 |
| WO1998016225A1 (en) | 1998-04-23 |
| ATE271867T1 (de) | 2004-08-15 |
| AU4757297A (en) | 1998-05-11 |
| JP2001502336A (ja) | 2001-02-20 |
| EP0946174A4 (de) | 2002-10-23 |
| IL129267A0 (en) | 2000-02-17 |
| DE69730045T2 (de) | 2005-07-21 |
| US5877198A (en) | 1999-03-02 |
| EP0946174A1 (de) | 1999-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |