IL129937A - Microparticulate form of tetrahydropyridine derivatives and pharmaceutical compositions comprising the same - Google Patents

Microparticulate form of tetrahydropyridine derivatives and pharmaceutical compositions comprising the same

Info

Publication number
IL129937A
IL129937A IL12993797A IL12993797A IL129937A IL 129937 A IL129937 A IL 129937A IL 12993797 A IL12993797 A IL 12993797A IL 12993797 A IL12993797 A IL 12993797A IL 129937 A IL129937 A IL 129937A
Authority
IL
Israel
Prior art keywords
micrometers
microparticulate form
active principle
particles
microparticulate
Prior art date
Application number
IL12993797A
Other languages
English (en)
Other versions
IL129937A0 (en
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of IL129937A0 publication Critical patent/IL129937A0/xx
Publication of IL129937A publication Critical patent/IL129937A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
IL12993797A 1996-12-23 1997-12-23 Microparticulate form of tetrahydropyridine derivatives and pharmaceutical compositions comprising the same IL129937A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9615905A FR2757510B1 (fr) 1996-12-23 1996-12-23 Forme microparticulaire d'un derive de tetrahydropyridine
PCT/FR1997/002394 WO1998028272A1 (fr) 1996-12-23 1997-12-23 Forme microparticulaire d'un derive de tetrahydropyridine

Publications (2)

Publication Number Publication Date
IL129937A0 IL129937A0 (en) 2000-02-29
IL129937A true IL129937A (en) 2002-09-12

Family

ID=9499044

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12993797A IL129937A (en) 1996-12-23 1997-12-23 Microparticulate form of tetrahydropyridine derivatives and pharmaceutical compositions comprising the same

Country Status (37)

Country Link
US (4) US20020028247A1 (th)
EP (1) EP0950051B1 (th)
JP (2) JP4422214B2 (th)
KR (1) KR100455797B1 (th)
CN (1) CN1088698C (th)
AR (1) AR009673A1 (th)
AT (1) ATE250032T1 (th)
AU (1) AU730302B2 (th)
BR (1) BR9714177A (th)
CA (1) CA2275593C (th)
CO (1) CO4920213A1 (th)
CZ (1) CZ294272B6 (th)
DE (1) DE69724999T2 (th)
DK (1) DK0950051T3 (th)
DZ (1) DZ2386A1 (th)
EE (1) EE04112B1 (th)
EG (1) EG24749A (th)
ES (1) ES2207758T3 (th)
FR (1) FR2757510B1 (th)
HU (1) HU224348B1 (th)
IL (1) IL129937A (th)
IN (1) IN186977B (th)
IS (1) IS2064B (th)
MY (1) MY126298A (th)
NO (1) NO311569B1 (th)
NZ (1) NZ336129A (th)
PL (1) PL190098B1 (th)
PT (1) PT950051E (th)
RU (1) RU2193031C2 (th)
SI (1) SI0950051T1 (th)
SK (1) SK283917B6 (th)
TR (1) TR199901362T2 (th)
TW (1) TW534820B (th)
UA (1) UA66776C2 (th)
WO (1) WO1998028272A1 (th)
YU (1) YU49427B (th)
ZA (1) ZA9711579B (th)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2739852T3 (es) * 2001-07-06 2020-02-04 Veloxis Pharmaceuticals As Aglomeración controlada
BE1015641A4 (fr) * 2003-05-26 2005-07-05 Mariani Jean Paul Micronisation 70.
RU2472490C1 (ru) * 2011-08-05 2013-01-20 Открытое акционерное общество "Биосинтез" Средство для лечения кожных гнойных инфекций, составы и способы получения

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US562883A (en) * 1896-06-30 Thill-coupling
FR2531707A1 (fr) * 1982-08-16 1984-02-17 Midy Spa Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques
US4826689A (en) * 1984-05-21 1989-05-02 University Of Rochester Method for making uniformly sized particles from water-insoluble organic compounds
FR2627696B1 (fr) * 1988-02-26 1991-09-13 Fournier Innovation Synergie Nouvelle forme galenique du fenofibrate
FR2639226B1 (fr) * 1988-11-18 1993-11-05 Sanofi Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles anxio-depressifs
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
ES2127835T3 (es) * 1992-10-26 1999-05-01 Sanol Arznei Schwarz Gmbh Procedimiento para la preparacion de microcapsulas.
US5662883A (en) * 1995-01-10 1997-09-02 Nanosystems L.L.C. Microprecipitation of micro-nanoparticulate pharmaceutical agents
US5560932A (en) * 1995-01-10 1996-10-01 Nano Systems L.L.C. Microprecipitation of nanoparticulate pharmaceutical agents
US6489334B2 (en) * 1996-12-23 2002-12-03 Sanofi-Synthelabo Method for the crystallization of a tetrahydropyridin derivative and resulting crystalline forms
FR2763847B1 (fr) * 1997-05-28 2003-06-06 Sanofi Sa Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1
US20020147216A1 (en) * 2000-01-31 2002-10-10 Yuhong Zhou Mucin synthesis inhibitors

Also Published As

Publication number Publication date
DE69724999T2 (de) 2004-07-22
FR2757510B1 (fr) 2000-01-07
PT950051E (pt) 2004-02-27
US20100021541A1 (en) 2010-01-28
DE69724999D1 (de) 2003-10-23
TR199901362T2 (xx) 1999-09-21
EP0950051A1 (fr) 1999-10-20
CZ229199A3 (cs) 1999-09-15
IS5077A (is) 1999-06-10
NO993077L (no) 1999-06-22
CN1241179A (zh) 2000-01-12
IL129937A0 (en) 2000-02-29
HUP0001181A2 (hu) 2000-11-28
ATE250032T1 (de) 2003-10-15
ES2207758T3 (es) 2004-06-01
AU730302B2 (en) 2001-03-01
UA66776C2 (uk) 2004-06-15
PL334276A1 (en) 2000-02-14
EG24749A (en) 2010-07-20
NO311569B1 (no) 2001-12-10
TW534820B (en) 2003-06-01
KR100455797B1 (ko) 2004-11-06
SK283917B6 (sk) 2004-05-04
CZ294272B6 (cs) 2004-11-10
US20020028247A1 (en) 2002-03-07
SI0950051T1 (en) 2004-02-29
CN1088698C (zh) 2002-08-07
CA2275593C (en) 2005-12-20
AR009673A1 (es) 2000-04-26
IN186977B (th) 2001-12-22
EE04112B1 (et) 2003-08-15
US20020192292A1 (en) 2002-12-19
HUP0001181A3 (en) 2003-03-28
YU28899A (sh) 2000-03-21
BR9714177A (pt) 2000-02-29
RU2193031C2 (ru) 2002-11-20
NZ336129A (en) 2000-11-24
IS2064B (is) 2005-11-15
YU49427B (sh) 2006-01-16
KR20000069503A (ko) 2000-11-25
ZA9711579B (en) 1998-06-25
EE9900263A (et) 2000-02-15
AU5668598A (en) 1998-07-17
US20080255365A1 (en) 2008-10-16
HU224348B1 (hu) 2005-08-29
CO4920213A1 (es) 2000-05-29
JP2009280581A (ja) 2009-12-03
FR2757510A1 (fr) 1998-06-26
PL190098B1 (pl) 2005-10-31
NO993077D0 (no) 1999-06-22
DZ2386A1 (fr) 2002-12-28
HK1024000A1 (en) 2000-09-29
JP4422214B2 (ja) 2010-02-24
SK82999A3 (en) 1999-12-10
DK0950051T3 (da) 2004-01-26
WO1998028272A1 (fr) 1998-07-02
CA2275593A1 (en) 1998-07-02
MY126298A (en) 2006-09-29
EP0950051B1 (fr) 2003-09-17
JP2001507013A (ja) 2001-05-29

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