|
US5605793A
(en)
|
1994-02-17 |
1997-02-25 |
Affymax Technologies N.V. |
Methods for in vitro recombination
|
|
US20060257890A1
(en)
|
1996-05-20 |
2006-11-16 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
|
US6117679A
(en)
|
1994-02-17 |
2000-09-12 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
|
US6335160B1
(en)
|
1995-02-17 |
2002-01-01 |
Maxygen, Inc. |
Methods and compositions for polypeptide engineering
|
|
US6995017B1
(en)
|
1994-02-17 |
2006-02-07 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
|
US6165793A
(en)
*
|
1996-03-25 |
2000-12-26 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
|
US6309883B1
(en)
|
1994-02-17 |
2001-10-30 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
|
US7148054B2
(en)
|
1997-01-17 |
2006-12-12 |
Maxygen, Inc. |
Evolution of whole cells and organisms by recursive sequence recombination
|
|
US6326204B1
(en)
|
1997-01-17 |
2001-12-04 |
Maxygen, Inc. |
Evolution of whole cells and organisms by recursive sequence recombination
|
|
US6153410A
(en)
*
|
1997-03-25 |
2000-11-28 |
California Institute Of Technology |
Recombination of polynucleotide sequences using random or defined primers
|
|
IL136574A0
(en)
|
1997-12-08 |
2001-06-14 |
California Inst Of Techn |
A method for forming a polynucleotide of desired properties
|
|
US7390619B1
(en)
|
1998-02-11 |
2008-06-24 |
Maxygen, Inc. |
Optimization of immunomodulatory properties of genetic vaccines
|
|
US6902918B1
(en)
|
1998-05-21 |
2005-06-07 |
California Institute Of Technology |
Oxygenase enzymes and screening method
|
|
US7153655B2
(en)
|
1998-06-16 |
2006-12-26 |
Alligator Bioscience Ab |
Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence
|
|
JP4700805B2
(ja)
*
|
1998-06-29 |
2011-06-15 |
ブリストル−マイヤーズ スクウィブ カンパニー |
多様性の高いライブラリーを製造する方法
|
|
EP1104459A1
(de)
|
1998-08-12 |
2001-06-06 |
Maxygen, Inc. |
Dna-shuffling von monooxygenase genen für die herstellung von industriellen chemikalien
|
|
AU6510799A
(en)
|
1998-10-07 |
2000-04-26 |
Maxygen, Inc. |
Dna shuffling to produce nucleic acids for mycotoxin detoxification
|
|
JP5043254B2
(ja)
|
1998-10-26 |
2012-10-10 |
ノボザイムス アクティーゼルスカブ |
糸状面細胞内の問題のdnaライブラリーの作製及びスクリーニング
|
|
EP1129184A1
(de)
|
1998-11-10 |
2001-09-05 |
Maxygen, Inc. |
Modifizierte adp-glukose pyrophosphorylase zur verbesserung und optimierung des phenotyps von pflanzen
|
|
EP2302044A1
(de)
*
|
1998-11-27 |
2011-03-30 |
Novozymes A/S |
Varianten eines lipolytischen Enzyms
|
|
US7312062B2
(en)
|
1998-11-27 |
2007-12-25 |
Novozymes A/S |
Lipolytic enzyme variants
|
|
US6436675B1
(en)
|
1999-09-28 |
2002-08-20 |
Maxygen, Inc. |
Use of codon-varied oligonucleotide synthesis for synthetic shuffling
|
|
US6376246B1
(en)
|
1999-02-05 |
2002-04-23 |
Maxygen, Inc. |
Oligonucleotide mediated nucleic acid recombination
|
|
US6917882B2
(en)
|
1999-01-19 |
2005-07-12 |
Maxygen, Inc. |
Methods for making character strings, polynucleotides and polypeptides having desired characteristics
|
|
US6961664B2
(en)
|
1999-01-19 |
2005-11-01 |
Maxygen |
Methods of populating data structures for use in evolutionary simulations
|
|
JP2002534965A
(ja)
|
1999-01-19 |
2002-10-22 |
マキシジェン, インコーポレイテッド |
所望の特徴を有する文字ストリング、ポリヌクレオチドおよびポリペプチドを作製するための方法
|
|
US7024312B1
(en)
|
1999-01-19 |
2006-04-04 |
Maxygen, Inc. |
Methods for making character strings, polynucleotides and polypeptides having desired characteristics
|
|
IL144657A0
(en)
|
1999-02-11 |
2002-06-30 |
Maxygen Inc |
High throughput mass spectrometry
|
|
US6531316B1
(en)
|
1999-03-05 |
2003-03-11 |
Maxyag, Inc. |
Encryption of traits using split gene sequences and engineered genetic elements
|
|
JP2003509010A
(ja)
*
|
1999-05-31 |
2003-03-11 |
ノボザイムス アクティーゼルスカブ |
ペプチドのスクリーニング方法
|
|
US7430477B2
(en)
|
1999-10-12 |
2008-09-30 |
Maxygen, Inc. |
Methods of populating data structures for use in evolutionary simulations
|
|
US6686515B1
(en)
|
1999-11-23 |
2004-02-03 |
Maxygen, Inc. |
Homologous recombination in plants
|
|
US7115712B1
(en)
|
1999-12-02 |
2006-10-03 |
Maxygen, Inc. |
Cytokine polypeptides
|
|
SG121902A1
(en)
|
2000-01-11 |
2006-05-26 |
Maxygen Inc |
Integrated systems for diversity generation and screening
|
|
US6248541B1
(en)
|
2000-04-21 |
2001-06-19 |
Genencor International, Inc. |
Screening under nutrient limited conditions
|
|
US6534292B1
(en)
|
2000-05-08 |
2003-03-18 |
Genencor International, Inc. |
Methods for forming recombined nucleic acids
|
|
US7115403B1
(en)
|
2000-05-16 |
2006-10-03 |
The California Institute Of Technology |
Directed evolution of galactose oxidase enzymes
|
|
EP1297146A2
(de)
|
2000-06-23 |
2003-04-02 |
Maxygen, Inc. |
Chimäre promotoren
|
|
AU2001272978A1
(en)
|
2000-06-23 |
2002-01-08 |
Maxygen, Inc. |
Novel co-stimulatory molecules
|
|
US6994963B1
(en)
*
|
2000-07-10 |
2006-02-07 |
Ambion, Inc. |
Methods for recombinatorial nucleic acid synthesis
|
|
US6858422B2
(en)
|
2000-07-13 |
2005-02-22 |
Codexis, Inc. |
Lipase genes
|
|
AUPQ974900A0
(en)
|
2000-08-29 |
2000-09-21 |
Macquarie Research Limited |
Degenerate oligonucleotide gene-shuffling
|
|
US6582914B1
(en)
|
2000-10-26 |
2003-06-24 |
Genencor International, Inc. |
Method for generating a library of oligonucleotides comprising a controlled distribution of mutations
|
|
WO2005012515A2
(en)
|
2003-04-29 |
2005-02-10 |
Pioneer Hi-Bred International, Inc. |
Novel glyphosate-n-acetyltransferase (gat) genes
|
|
WO2002046396A1
(en)
*
|
2000-12-06 |
2002-06-13 |
Novozymes A/S |
Method for producing a polynucleotide library
|
|
US6783941B2
(en)
|
2000-12-06 |
2004-08-31 |
Novozymes A/S |
Method for producing a polynucleotide library in vitro by mismatch repair of heteroduplexes
|
|
US6958213B2
(en)
|
2000-12-12 |
2005-10-25 |
Alligator Bioscience Ab |
Method for in vitro molecular evolution of protein function
|
|
AU2002307340A1
(en)
|
2001-04-16 |
2002-10-28 |
California Institute Of Technology |
Peroxide-driven cytochrome p450 oxygenase variants
|
|
US7226768B2
(en)
|
2001-07-20 |
2007-06-05 |
The California Institute Of Technology |
Cytochrome P450 oxygenases
|
|
EP2315145B1
(de)
|
2002-03-01 |
2015-11-25 |
Codexis Mayflower Holdings, LLC |
Verfahren, Systeme und Software zur Erkennung von funktionalen Biomolekülen
|
|
WO2003078583A2
(en)
|
2002-03-09 |
2003-09-25 |
Maxygen, Inc. |
Optimization of crossover points for directed evolution
|
|
US7226771B2
(en)
|
2002-04-19 |
2007-06-05 |
Diversa Corporation |
Phospholipases, nucleic acids encoding them and methods for making and using them
|
|
EP1497418B1
(de)
|
2002-04-19 |
2012-10-17 |
Verenium Corporation |
Phospholipasen, diese codierende nukleinsäuren sowie verfahren zu ihrer herstellung und verwendung
|
|
ATE356871T1
(de)
|
2002-05-17 |
2007-04-15 |
Alligator Bioscience Ab |
Eine methode zur in vitro molekularen evolution der proteinfunktion
|
|
US9321832B2
(en)
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
|
AU2003304275A1
(en)
|
2002-08-06 |
2005-01-21 |
Pioneer Hi-Bred International, Inc. |
Ap1 amine oxidase variants
|
|
WO2004016811A2
(en)
*
|
2002-08-19 |
2004-02-26 |
Danmarks Tekniske Universitet (Dtu) |
Methods and kit for genes shuffling using tagged primers
|
|
EP2194133B1
(de)
|
2003-03-06 |
2015-12-02 |
BASF Enzymes LLC |
Amylasen, Nukleinsäuren, die diese codieren, und Verfahren zu deren Herstellung und Verwendung
|
|
CA2515583C
(en)
|
2003-03-07 |
2015-07-14 |
Diversa Corporation |
Hydrolases, nucleic acids encoding them and methods for making and using them
|
|
EP1613733B1
(de)
|
2003-04-04 |
2015-06-03 |
BASF Enzymes LLC |
Pektatlyasen, diese codierende nukleinsäuren und verfahren zu deren herstellung und verwendung
|
|
WO2005017105A2
(en)
|
2003-06-17 |
2005-02-24 |
California University Of Technology |
Regio- and enantioselective alkane hydroxylation with modified cytochrome p450
|
|
CN103484486B
(zh)
|
2003-07-02 |
2018-04-24 |
维莱尼姆公司 |
葡聚糖酶,编码它们的核酸以及制备和使用它们的方法
|
|
WO2005017116A2
(en)
|
2003-08-11 |
2005-02-24 |
California Institute Of Technology |
Thermostable peroxide-driven cytochrome p450 oxygenase variants and methods of use
|
|
US7741089B2
(en)
|
2003-08-11 |
2010-06-22 |
Verenium Corporation |
Laccases, nucleic acids encoding them and methods for making and using them
|
|
ES2352172T3
(es)
|
2004-06-09 |
2011-02-16 |
Pioneer-Hi-Bred International, Inc. |
Péptidos de transito de plastidio.
|
|
AU2005264938B2
(en)
|
2004-06-16 |
2011-11-24 |
Verenium Corporation |
Compositions and methods for enzymatic decolorization of chlorophyll
|
|
EP1869174B1
(de)
|
2005-03-10 |
2015-02-18 |
BASF Enzymes LLC |
Lyase-enzyme, nukleinsäuren zu deren kodierung und verfahren zu deren herstellung und verwendung
|
|
EA018577B1
(ru)
|
2005-03-15 |
2013-09-30 |
Верениум Корпорейшн |
Целлюлазы, нуклеиновые кислоты, кодирующие их, и способы их получения и применения
|
|
US8715988B2
(en)
|
2005-03-28 |
2014-05-06 |
California Institute Of Technology |
Alkane oxidation by modified hydroxylases
|
|
US11214817B2
(en)
|
2005-03-28 |
2022-01-04 |
California Institute Of Technology |
Alkane oxidation by modified hydroxylases
|
|
CN100366752C
(zh)
*
|
2005-12-28 |
2008-02-06 |
河北省农林科学院遗传生理研究所 |
一种利用原子变构衍生dna序列多样性的方法
|
|
EP1987142A4
(de)
|
2006-02-02 |
2009-07-15 |
Verenium Corp |
Esterasen und damit zusammenhängende nukleinsäuren und verfahren
|
|
NZ595502A
(en)
|
2006-02-10 |
2013-11-29 |
Verenium Corp |
Cellulolytic enzymes, nucleic acids encoding them and methods for making and using them
|
|
ES2682284T3
(es)
|
2006-02-14 |
2018-09-19 |
Bp Corporation North America Inc. |
Xilanasas, ácidos nucleicos que las codifican y métodos para elaborarlas y usarlas
|
|
ES2416104T3
(es)
|
2006-03-07 |
2013-07-30 |
Cargill, Incorporated |
Aldolasas, ácidos nucleicos que las codifican y métodos para producir y usar las mismas
|
|
KR101622894B1
(ko)
|
2006-03-07 |
2016-05-19 |
바스프 엔자임스 엘엘씨 |
알돌라제, 이것을 코딩하는 핵산과 그 제조 방법 및 사용 방법
|
|
CN106222185B
(zh)
|
2006-08-04 |
2021-12-03 |
维莱尼姆公司 |
葡聚糖酶、编码它们的核酸及制备和使用它们的方法
|
|
US8252559B2
(en)
|
2006-08-04 |
2012-08-28 |
The California Institute Of Technology |
Methods and systems for selective fluorination of organic molecules
|
|
EP2069513A4
(de)
|
2006-08-04 |
2012-03-21 |
California Inst Of Techn |
Verfahren und systeme zur selektiven fluorinierung organischer moleküle
|
|
US8877478B2
(en)
|
2006-09-21 |
2014-11-04 |
Verenium Corporation |
Phytases, nucleic acids encoding them and methods for making and using them
|
|
EP2057274B1
(de)
|
2006-09-21 |
2013-12-11 |
DSM IP Assets B.V. |
Phospholipase ,nukleinsaüre, die diese kodieren und verfahren zur ihrer herstellung und verwendung
|
|
PL3101128T3
(pl)
|
2006-12-21 |
2019-09-30 |
Basf Enzymes Llc |
Amylazy i glukoamylazy, kwasy nukleinowe kodujące te związki oraz sposoby wytwarzania tych związków oraz stosowania ich
|
|
CN104212822A
(zh)
|
2007-01-30 |
2014-12-17 |
Bp法人北美有限公司 |
用于处理木质纤维素的酶、编码它们的核酸及其制备和应用方法
|
|
NZ601191A
(en)
|
2007-10-03 |
2014-01-31 |
Verenium Corp |
Xylanases, nucleic acids encoding them and methods for making and using them
|
|
AU2008347234B2
(en)
|
2008-01-03 |
2015-05-28 |
Basf Enzymes Llc |
Transferases and oxidoreductases, nucleic acids encoding them and methods for making and using them
|
|
CA2710922A1
(en)
|
2008-01-03 |
2009-07-16 |
Verenium Corporation |
Isomerases, nucleic acids encoding them and methods for making and using them
|
|
EP2297310A2
(de)
|
2008-05-23 |
2011-03-23 |
E. I. du Pont de Nemours and Company |
Neue dgat-gene für gesteigerte samenspeicherlipidproduktion und veränderte fettsäureprofile bei ölsamenpflanzen
|
|
US8551752B2
(en)
*
|
2008-08-08 |
2013-10-08 |
Tosoh Corporation |
RNA polymerase mutant with improved functions
|
|
US8198062B2
(en)
|
2008-08-29 |
2012-06-12 |
Dsm Ip Assets B.V. |
Hydrolases, nucleic acids encoding them and methods for making and using them
|
|
DK2346995T3
(en)
|
2008-09-26 |
2019-02-11 |
Tocagen Inc |
GENETERIVE VECTORS AND CYTOSINDEAMINASES
|
|
HUE030948T2
(en)
|
2009-05-21 |
2017-06-28 |
Basf Enzymes Llc |
Phytases, nucleic acids and processes encoding them for their production and use
|
|
UA111708C2
(uk)
|
2009-10-16 |
2016-06-10 |
Бандж Ойлз, Інк. |
Спосіб рафінування олії
|
|
UA109884C2
(uk)
|
2009-10-16 |
2015-10-26 |
|
Поліпептид, що має активність ферменту фосфатидилінозитол-специфічної фосфоліпази с, нуклеїнова кислота, що його кодує, та спосіб його виробництва і застосування
|
|
JP2013525285A
(ja)
|
2010-04-08 |
2013-06-20 |
サンフォード−バーナム メディカル リサーチ インスティテュート |
化合物の送達を増強するための方法および組成物
|
|
CA2805941A1
(en)
|
2010-08-13 |
2012-02-16 |
Pioneer Hi-Bred International, Inc. |
Methods and compositions for targeting sequences of interest to the chloroplast
|
|
CN102560688B
(zh)
*
|
2010-12-15 |
2013-11-20 |
深圳华大基因科技服务有限公司 |
一种新的基于illumina测序平台的文库构建方法
|
|
WO2013016207A2
(en)
|
2011-07-22 |
2013-01-31 |
California Institute Of Technology |
Stable fungal cel6 enzyme variants
|
|
US20150184173A1
(en)
|
2012-05-04 |
2015-07-02 |
E I Du Pont De Nemours And Company |
Compositions and methods comprising sequences having meganuclease activity
|
|
US9663532B2
(en)
|
2012-10-29 |
2017-05-30 |
University Of Rochester |
Artemisinin derivatives, methods for their preparation and their use as antimalarial agents
|
|
EP2970995A1
(de)
|
2013-03-14 |
2016-01-20 |
Pioneer Hi-Bred International, Inc. |
Zusammensetzungen mit dicamba-decarboxylaseaktivität und verfahren zur verwendung
|
|
CA2904537A1
(en)
|
2013-03-14 |
2014-09-25 |
Pioneer Hi-Bred International, Inc. |
Compositions having dicamba decarboxylase activity and methods of use
|
|
US10006045B2
(en)
|
2013-08-16 |
2018-06-26 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
|
BR122020001770B1
(pt)
|
2013-09-13 |
2022-11-29 |
Pioneer Hi-Bred International, Inc |
Construto de dna, método de obtenção de planta transgênica, proteína de fusão, método para controlar uma população de praga de inseto, método para inibir o crescimento ou matar uma praga de inseto
|
|
CN103539744B
(zh)
*
|
2013-10-17 |
2016-03-23 |
北京颖泰嘉和生物科技股份有限公司 |
一种制备3-(3,5-二氯苯基)-2,4-咪唑烷二酮的方法
|
|
WO2015100277A2
(en)
|
2013-12-23 |
2015-07-02 |
University Of Rochester |
Methods and compositions for ribosomal synthesis of macrocyclic peptides
|
|
CN114763376A
(zh)
|
2014-02-07 |
2022-07-19 |
先锋国际良种公司 |
杀昆虫蛋白及其使用方法
|
|
RU2747978C2
(ru)
|
2014-02-07 |
2021-05-18 |
Пайонир Хай-Бред Интернэшнл, Инк. |
Инсектицидные белки и способы их применения
|
|
WO2016061206A1
(en)
|
2014-10-16 |
2016-04-21 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
|
EP4663761A3
(de)
|
2015-01-15 |
2026-03-04 |
Pioneer Hi-Bred International, Inc. |
Insektizidproteine und verfahren zu deren verwendung
|
|
US20180245070A1
(en)
*
|
2015-02-27 |
2018-08-30 |
The University Of Hong Kong |
Dna display and methods thereof
|
|
MX376048B
(es)
|
2015-03-11 |
2025-03-07 |
Corteva Agriscience Llc |
Combinaciones insecticidas de pip-72 y métodos de uso.
|
|
CA2985198A1
(en)
|
2015-05-19 |
2016-11-24 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
|
CN116003550A
(zh)
|
2015-08-06 |
2023-04-25 |
先锋国际良种公司 |
植物来源的杀昆虫蛋白及其使用方法
|
|
EP3390431A1
(de)
|
2015-12-18 |
2018-10-24 |
Pioneer Hi-Bred International, Inc. |
Insektizide proteine und verfahren zu deren verwendung
|
|
CN109068660B
(zh)
|
2016-05-04 |
2023-05-02 |
先锋国际良种公司 |
杀昆虫蛋白及其使用方法
|
|
CN109788735A
(zh)
|
2016-07-01 |
2019-05-21 |
先锋国际良种公司 |
来自植物的杀昆虫蛋白及其使用方法
|
|
CN109863167B
(zh)
|
2016-11-01 |
2022-12-23 |
先锋国际良种公司 |
杀昆虫蛋白及其使用方法
|
|
CA3044404A1
(en)
|
2016-12-14 |
2018-06-21 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
|
MX2019007491A
(es)
|
2016-12-22 |
2019-09-06 |
Pioneer Hi Bred Int |
Proteinas insecticidas y metodos para su uso.
|
|
MX2019009371A
(es)
|
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|
|
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(ru)
|
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|
|
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(en)
|
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|
|
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(zh)
|
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|
|
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(en)
|
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|
|
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(zh)
*
|
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|
|
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|
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|
|
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|
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|
|
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(en)
*
|
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|
|
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(zh)
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|
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|
|
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(en)
|
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|