IL133112A - Controlled release microencapsulated ngf formulation - Google Patents

Controlled release microencapsulated ngf formulation

Info

Publication number
IL133112A
IL133112A IL13311298A IL13311298A IL133112A IL 133112 A IL133112 A IL 133112A IL 13311298 A IL13311298 A IL 13311298A IL 13311298 A IL13311298 A IL 13311298A IL 133112 A IL133112 A IL 133112A
Authority
IL
Israel
Prior art keywords
ngf
zinc
metal
calcium
acid
Prior art date
Application number
IL13311298A
Other languages
English (en)
Other versions
IL133112A0 (en
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of IL133112A0 publication Critical patent/IL133112A0/xx
Publication of IL133112A publication Critical patent/IL133112A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/52—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an inorganic compound, e.g. an inorganic ion that is complexed with the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL13311298A 1997-06-13 1998-06-11 Controlled release microencapsulated ngf formulation IL133112A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/874,647 US6113947A (en) 1997-06-13 1997-06-13 Controlled release microencapsulated NGF formulation
PCT/US1998/011600 WO1998056426A1 (en) 1997-06-13 1998-06-11 Controlled release microencapsulated ngf formulation

Publications (2)

Publication Number Publication Date
IL133112A0 IL133112A0 (en) 2001-03-19
IL133112A true IL133112A (en) 2004-09-27

Family

ID=25364245

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13311298A IL133112A (en) 1997-06-13 1998-06-11 Controlled release microencapsulated ngf formulation

Country Status (12)

Country Link
US (1) US6113947A (de)
EP (1) EP1001814B1 (de)
JP (1) JP4316682B2 (de)
AR (1) AR012978A1 (de)
AT (1) ATE275975T1 (de)
AU (1) AU730612B2 (de)
CA (1) CA2293575C (de)
DE (1) DE69826289T2 (de)
ES (1) ES2227844T3 (de)
IL (1) IL133112A (de)
WO (1) WO1998056426A1 (de)
ZA (1) ZA985138B (de)

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Also Published As

Publication number Publication date
IL133112A0 (en) 2001-03-19
ATE275975T1 (de) 2004-10-15
ZA985138B (en) 1999-12-13
JP2002505671A (ja) 2002-02-19
EP1001814B1 (de) 2004-09-15
CA2293575A1 (en) 1998-12-17
DE69826289D1 (de) 2004-10-21
WO1998056426A1 (en) 1998-12-17
AR012978A1 (es) 2000-11-22
US6113947A (en) 2000-09-05
CA2293575C (en) 2009-01-06
ES2227844T3 (es) 2005-04-01
AU8059298A (en) 1998-12-30
AU730612B2 (en) 2001-03-08
EP1001814A1 (de) 2000-05-24
JP4316682B2 (ja) 2009-08-19
DE69826289T2 (de) 2005-09-22

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