IL137466A0 - Breast cancer resistance protein (bcrp) and the dna which encodes it - Google Patents
Breast cancer resistance protein (bcrp) and the dna which encodes itInfo
- Publication number
- IL137466A0 IL137466A0 IL13746699A IL13746699A IL137466A0 IL 137466 A0 IL137466 A0 IL 137466A0 IL 13746699 A IL13746699 A IL 13746699A IL 13746699 A IL13746699 A IL 13746699A IL 137466 A0 IL137466 A0 IL 137466A0
- Authority
- IL
- Israel
- Prior art keywords
- breast cancer
- bcrp
- encodes
- dna
- resistance protein
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/44—Multiple drug resistance
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7376398P | 1998-02-05 | 1998-02-05 | |
| PCT/US1999/002577 WO1999040110A1 (fr) | 1998-02-05 | 1999-02-05 | Proteine de resistance aux medicaments contre le cancer du sein (bcrp) et adn codant cette proteine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL137466A0 true IL137466A0 (en) | 2001-07-24 |
Family
ID=22115664
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13746699A IL137466A0 (en) | 1998-02-05 | 1999-02-05 | Breast cancer resistance protein (bcrp) and the dna which encodes it |
| IL137466A IL137466A (en) | 1998-02-05 | 2000-07-24 | Polynucleotides of breast cancer resistance proteins (bcrp), nucleic acids, plasmids and expression vectors encoding the same |
| IL177612A IL177612A (en) | 1998-02-05 | 2006-08-21 | Breast cancer resistance protein (bcrp) and methods for identifying inhibitors thereof |
| IL191982A IL191982A (en) | 1998-02-05 | 2008-06-05 | Antibody binding to breast cancer resistance protein (bcrp) and screening methods using the same |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL137466A IL137466A (en) | 1998-02-05 | 2000-07-24 | Polynucleotides of breast cancer resistance proteins (bcrp), nucleic acids, plasmids and expression vectors encoding the same |
| IL177612A IL177612A (en) | 1998-02-05 | 2006-08-21 | Breast cancer resistance protein (bcrp) and methods for identifying inhibitors thereof |
| IL191982A IL191982A (en) | 1998-02-05 | 2008-06-05 | Antibody binding to breast cancer resistance protein (bcrp) and screening methods using the same |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US6313277B1 (fr) |
| EP (1) | EP1054894B2 (fr) |
| JP (1) | JP4187412B2 (fr) |
| AT (1) | ATE359291T1 (fr) |
| AU (1) | AU755567B2 (fr) |
| CA (1) | CA2319715C (fr) |
| DE (1) | DE69935782T3 (fr) |
| ES (1) | ES2284243T5 (fr) |
| IL (4) | IL137466A0 (fr) |
| WO (1) | WO1999040110A1 (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU755567B2 (en) * | 1998-02-05 | 2002-12-12 | University Of Maryland At Baltimore | Breast cancer resistance protein (BCRP) and the DNA which encodes it |
| US7622557B2 (en) | 1998-05-28 | 2009-11-24 | St. Jude Children's Research Hospital | Antibodies having binding specificity for the extracellular domain of a breast cancer resistance protein (BCRP) |
| AU4214799A (en) | 1998-05-28 | 1999-12-13 | St. Jude Children's Research Hospital | Expansion of hematopoietic stem cells transduced with mdr-1 and methods of use thereof |
| AU1924000A (en) * | 1998-11-30 | 2000-07-03 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | An atp-binding cassette protein responsible for cytotoxin resistance |
| US7138493B1 (en) | 1998-11-30 | 2006-11-21 | The United States Of America As Represented By The Department Of Health And Human Services | ATP-binding cassette protein responsible for cytotoxin resistance |
| AU4955200A (en) | 1999-05-17 | 2000-12-05 | Cancer Research Ventures Limited | A method of improving bioavailability of orally administered drugs, a method of screening for enhancers of such bioavailability and novel pharmaceutical compositions for oral delivery of drugs |
| AU2001288061A1 (en) * | 2000-10-03 | 2002-04-15 | Banyu Pharmaceutical Co., Ltd. | Drug resistance-associated gene and use thereof |
| HU0100947D0 (en) * | 2001-03-02 | 2001-05-28 | Solvo Kft | Screening system based on expression of abcg2 half transporter protein in an expression system free of other abc-transporters, abcg2 homodimers |
| US20050255084A1 (en) * | 2001-10-24 | 2005-11-17 | Solvo Biotechnology | Use of a half-transporter protein of the abcg-family for selecting cells and in gene therapy |
| EP1591112A4 (fr) * | 2003-02-04 | 2006-06-14 | Yakult Honsha Kk | Inhibiteur de la proteine resistant au cancer du sein |
| JP2006069910A (ja) * | 2004-08-31 | 2006-03-16 | Yoshiichi Sugimoto | 抗癌剤耐性克服剤 |
| EP1672365A1 (fr) * | 2004-12-16 | 2006-06-21 | Het Nederlands Kanker Instituut | Moyens et procédés pour déterminer et/ou influencer le transfert cellulair |
| US7465788B2 (en) * | 2005-01-18 | 2008-12-16 | University Of Maryland | Breast cancer resistance protein (BCRP) and antibodies thereto |
| KR102211189B1 (ko) | 2012-09-11 | 2021-02-03 | 코닝 인코포레이티드 | 약물 트랜스포터 단백질(들) 및/또는 약물대사 효소(들)를 인코딩하는 유전자(들)를 일시적으로 과발현하는 소모성 냉동보존 세포 |
| KR101561965B1 (ko) | 2013-11-27 | 2015-10-20 | 한국과학기술연구원 | 디스코이딘 도메인 수용체 2 활성을 조절하는 물질의 동정 방법 |
| US20220256794A1 (en) * | 2019-05-08 | 2022-08-18 | The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization | Terpene synthases and transporters |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5585479A (en) * | 1992-07-24 | 1996-12-17 | The United States Of America As Represented By The Secretary Of The Navy | Antisense oligonucleotides directed against human ELAM-I RNA |
| US5489519A (en) * | 1992-10-27 | 1996-02-06 | Queen's University At Kingston | Multidrug resistance protein |
| US6060248A (en) * | 1997-02-24 | 2000-05-09 | Tm Technologies, Inc. | Process for selecting anti-sense oligonucleotides |
| AU7807298A (en) * | 1997-06-04 | 1998-12-21 | Genetics Institute Inc. | Secreted proteins and polynucleotides encoding them |
| AU755567B2 (en) * | 1998-02-05 | 2002-12-12 | University Of Maryland At Baltimore | Breast cancer resistance protein (BCRP) and the DNA which encodes it |
| WO1999058675A2 (fr) * | 1998-05-14 | 1999-11-18 | Chiron Corporation | Genes humains et produits d'expression genique v |
| WO2000018912A2 (fr) * | 1998-09-25 | 2000-04-06 | Bayer Aktiengesellschaft | Genes et proteines de cassette de liaison avec atp, destines au diagnostic et au traitement de desordres lipidiques et maladies inflammatoires |
| AU1924000A (en) * | 1998-11-30 | 2000-07-03 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | An atp-binding cassette protein responsible for cytotoxin resistance |
| AU2001288061A1 (en) | 2000-10-03 | 2002-04-15 | Banyu Pharmaceutical Co., Ltd. | Drug resistance-associated gene and use thereof |
| CA2489474A1 (fr) | 2002-06-17 | 2003-12-24 | Banyu Pharmaceutical Co., Ltd. | Procede permettant de prevoir la capacite de transport d'un medicament par des polymorphismes abcg2 |
-
1999
- 1999-02-05 AU AU27610/99A patent/AU755567B2/en not_active Expired
- 1999-02-05 US US09/245,808 patent/US6313277B1/en not_active Expired - Lifetime
- 1999-02-05 CA CA2319715A patent/CA2319715C/fr not_active Expired - Lifetime
- 1999-02-05 DE DE69935782.9T patent/DE69935782T3/de not_active Expired - Lifetime
- 1999-02-05 WO PCT/US1999/002577 patent/WO1999040110A1/fr not_active Ceased
- 1999-02-05 IL IL13746699A patent/IL137466A0/xx unknown
- 1999-02-05 ES ES99908097.1T patent/ES2284243T5/es not_active Expired - Lifetime
- 1999-02-05 JP JP2000530538A patent/JP4187412B2/ja not_active Expired - Lifetime
- 1999-02-05 EP EP99908097.1A patent/EP1054894B2/fr not_active Expired - Lifetime
- 1999-02-05 AT AT99908097T patent/ATE359291T1/de not_active IP Right Cessation
-
2000
- 2000-07-24 IL IL137466A patent/IL137466A/en not_active IP Right Cessation
-
2001
- 2001-09-21 US US09/961,086 patent/US7541437B2/en not_active Expired - Fee Related
-
2005
- 2005-07-20 US US11/184,860 patent/US7655755B2/en not_active Expired - Fee Related
-
2006
- 2006-08-21 IL IL177612A patent/IL177612A/en not_active IP Right Cessation
-
2008
- 2008-04-01 US US12/060,738 patent/US7741445B2/en not_active Expired - Fee Related
- 2008-06-05 IL IL191982A patent/IL191982A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2284243T5 (es) | 2017-08-22 |
| IL177612A (en) | 2011-04-28 |
| DE69935782D1 (de) | 2007-05-24 |
| IL137466A (en) | 2011-04-28 |
| US20090104199A1 (en) | 2009-04-23 |
| US7655755B2 (en) | 2010-02-02 |
| US20030036645A1 (en) | 2003-02-20 |
| US7741445B2 (en) | 2010-06-22 |
| EP1054894B2 (fr) | 2016-11-09 |
| ATE359291T1 (de) | 2007-05-15 |
| AU2761099A (en) | 1999-08-23 |
| US20050272684A1 (en) | 2005-12-08 |
| JP2002502592A (ja) | 2002-01-29 |
| WO1999040110A1 (fr) | 1999-08-12 |
| CA2319715C (fr) | 2012-08-07 |
| US6313277B1 (en) | 2001-11-06 |
| IL191982A (en) | 2011-09-27 |
| EP1054894B1 (fr) | 2007-04-11 |
| DE69935782T3 (de) | 2017-01-05 |
| CA2319715A1 (fr) | 1999-08-12 |
| ES2284243T3 (es) | 2007-11-01 |
| JP4187412B2 (ja) | 2008-11-26 |
| IL191982A0 (en) | 2008-12-29 |
| US7541437B2 (en) | 2009-06-02 |
| DE69935782T2 (de) | 2007-08-16 |
| EP1054894A4 (fr) | 2002-03-13 |
| EP1054894A1 (fr) | 2000-11-29 |
| AU755567B2 (en) | 2002-12-12 |
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