IL137774A0 - Cytostatic agents - Google Patents

Cytostatic agents

Info

Publication number
IL137774A0
IL137774A0 IL13777498A IL13777498A IL137774A0 IL 137774 A0 IL137774 A0 IL 137774A0 IL 13777498 A IL13777498 A IL 13777498A IL 13777498 A IL13777498 A IL 13777498A IL 137774 A0 IL137774 A0 IL 137774A0
Authority
IL
Israel
Prior art keywords
hydroxycarbamoyl
enoylamino
hex
isobutyl
methyl
Prior art date
Application number
IL13777498A
Other languages
English (en)
Original Assignee
British Biotech Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Biotech Pharm filed Critical British Biotech Pharm
Publication of IL137774A0 publication Critical patent/IL137774A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
IL13777498A 1998-03-12 1998-03-12 Cytostatic agents IL137774A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB1998/000754 WO1999046241A1 (en) 1998-03-12 1998-03-12 Cytostatic agents

Publications (1)

Publication Number Publication Date
IL137774A0 true IL137774A0 (en) 2001-10-31

Family

ID=10825272

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13777498A IL137774A0 (en) 1998-03-12 1998-03-12 Cytostatic agents
IL137774A IL137774A (en) 1998-03-12 2000-08-09 Cytostatic substances

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL137774A IL137774A (en) 1998-03-12 2000-08-09 Cytostatic substances

Country Status (17)

Country Link
EP (1) EP1062202B1 (cs)
JP (1) JP4324324B2 (cs)
KR (1) KR20010041661A (cs)
CN (1) CN1141292C (cs)
AT (1) ATE231122T1 (cs)
AU (1) AU747977B2 (cs)
BR (1) BR9815717A (cs)
CA (1) CA2323414C (cs)
CZ (1) CZ299610B6 (cs)
DE (1) DE69810817T2 (cs)
GB (1) GB2349149A (cs)
HU (1) HUP0100999A2 (cs)
IL (2) IL137774A0 (cs)
NO (1) NO20004528L (cs)
NZ (1) NZ506293A (cs)
PL (1) PL190637B1 (cs)
WO (1) WO1999046241A1 (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9901863D0 (en) 1999-01-29 1999-03-17 British Biotech Pharm Antibacterial agents
WO2019039937A1 (en) 2017-08-21 2019-02-28 Stichting Vumc POLYTHERAPY FOR THE TREATMENT OF CANCER
US10925851B2 (en) 2018-03-15 2021-02-23 Regents Of The University Of Minnesota Use of Tosedostat and related compounds as analgesics

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0639982A1 (en) * 1992-05-01 1995-03-01 British Biotech Pharmaceuticals Limited Use of mmp inhibitors
GB9215665D0 (en) * 1992-07-23 1992-09-09 British Bio Technology Compounds
US5691381A (en) * 1995-04-18 1997-11-25 The Dupont Merck Pharmaceutical Company Hydroxamic and carbocyclic acids as metalloprotease inhibitors
JP4238334B2 (ja) * 1996-09-10 2009-03-18 ヴァーナリス (アールアンドディー) リミテッド 細胞増殖抑制性ヒドロキサム酸誘導体

Also Published As

Publication number Publication date
CA2323414C (en) 2008-05-13
PL342811A1 (en) 2001-07-02
HUP0100999A2 (hu) 2001-08-28
IL137774A (en) 2006-07-05
AU747977B2 (en) 2002-05-30
EP1062202B1 (en) 2003-01-15
KR20010041661A (ko) 2001-05-25
GB2349149A (en) 2000-10-25
DE69810817T2 (de) 2003-11-20
CZ20003317A3 (cs) 2001-03-14
JP4324324B2 (ja) 2009-09-02
EP1062202A1 (en) 2000-12-27
BR9815717A (pt) 2000-11-07
JP2002506057A (ja) 2002-02-26
GB0019414D0 (en) 2000-09-27
WO1999046241A1 (en) 1999-09-16
PL190637B1 (pl) 2005-12-30
NZ506293A (en) 2003-05-30
CN1141292C (zh) 2004-03-10
ATE231122T1 (de) 2003-02-15
NO20004528D0 (no) 2000-09-11
NO20004528L (no) 2000-09-11
CA2323414A1 (en) 1999-09-16
CN1286681A (zh) 2001-03-07
DE69810817D1 (de) 2003-02-20
AU6410698A (en) 1999-09-27
CZ299610B6 (cs) 2008-09-17

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed