IL140468A0 - Benzoxazole derivatives and pharmaceutical compositions containing the same - Google Patents

Benzoxazole derivatives and pharmaceutical compositions containing the same

Info

Publication number: IL140468A0
Authority: IL; Israel
Prior art keywords: same; pharmaceutical compositions; compositions containing; benzoxazole derivatives; pde
Prior art date: 1998-07-06

Application number

IL14046899A

Other languages

English (en)

Original Assignee

Byk Gulden Lomberg Chem Fab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-07-06

Filing date

1999-06-26

Publication date

2002-02-10

1999-06-26 Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab

2002-02-10 Publication of IL140468A0 publication Critical patent/IL140468A0/xx

Links

BCMCBBGGLRIHSE-UHFFFAOYSA-N 1,3-benzoxazole Chemical class C1=CC=C2OC=NC2=C1 BCMCBBGGLRIHSE-UHFFFAOYSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
239000003814 drug Substances 0.000 abstract 2
101000909851 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) cAMP/cGMP dual specificity phosphodiesterase Rv0805 Proteins 0.000 abstract 1
102000004861 Phosphoric Diester Hydrolases Human genes 0.000 abstract 1
108090001050 Phosphoric Diester Hydrolases Proteins 0.000 abstract 1
238000010521 absorption reaction Methods 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
231100000053 low toxicity Toxicity 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

IL14046899A 1998-07-06 1999-06-26 Benzoxazole derivatives and pharmaceutical compositions containing the same IL140468A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98112469		1998-07-06
PCT/EP1999/004451 WO2000001695A1 (en)	1998-07-06	1999-06-26	New benzoxazoles with pde-inhibiting activity

Publications (1)

Publication Number	Publication Date
IL140468A0 true IL140468A0 (en)	2002-02-10

Family

ID=8232222

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL14046899A IL140468A0 (en)	1998-07-06	1999-06-26	Benzoxazole derivatives and pharmaceutical compositions containing the same

Country Status (14)

Country	Link
US (1)	US6376485B1 (de)
EP (1)	EP1095040B1 (de)
JP (1)	JP2002519423A (de)
AT (1)	ATE263166T1 (de)
AU (1)	AU761647B2 (de)
CA (1)	CA2336894A1 (de)
DE (1)	DE69916066T2 (de)
DK (1)	DK1095040T3 (de)
ES (1)	ES2219031T3 (de)
IL (1)	IL140468A0 (de)
PT (1)	PT1095040E (de)
SI (1)	SI1095040T1 (de)
WO (1)	WO2000001695A1 (de)
ZA (1)	ZA200100088B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA83620C2 (ru)	2001-12-05	2008-08-11	Уайт	Замещенные бензоксазолы и их аналоги как эстрогенные агенты
EP2258359A3 (de)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenese durch Modulation des Muscarinrezeptors mit Sabcomelin
JP2009506069A (ja)	2005-08-26	2009-02-12	ブレインセルス，インコーポレイティド	ムスカリン性受容体調節による神経発生
US7985756B2 (en)	2005-10-21	2011-07-26	Braincells Inc.	Modulation of neurogenesis by PDE inhibition
WO2007053596A1 (en)	2005-10-31	2007-05-10	Braincells, Inc.	Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
WO2007134077A2 (en)	2006-05-09	2007-11-22	Braincells, Inc.	5 ht receptor mediated neurogenesis
WO2007134136A2 (en)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenesis by modulating angiotensin
EP2068872A1 (de)	2006-09-08	2009-06-17	Braincells, Inc.	Kombinationen mit einem 4-acylaminopyridin-derivat
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
JP5524853B2 (ja) *	2007-11-21	2014-06-18	デコードジェネティクスイーエイチエフ	肺疾患及び心臓血管疾患を治療するための置換されたベンゾアゾールｐｄｅ４阻害剤
WO2010099217A1 (en)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
EP2804603A1 (de)	2012-01-10	2014-11-26	President and Fellows of Harvard College	Betazellen-replikation für promoterverbindungen und verwendungsverfahren dafür

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4405633A (en) *	1982-03-01	1983-09-20	Usv Pharmaceutical Corporation	Method of treatment of asthma
US4490373A (en) *	1983-05-20	1984-12-25	Usv Pharmaceutical Corporation	Method of treating asthma
WO1996011917A1 (en) *	1994-10-12	1996-04-25	Euro-Celtique, S.A.	Novel benzoxazoles
DE59610031D1 (de) *	1995-05-18	2003-02-06	Altana Pharma Ag	Cyclohexyldihydrobenzofurane
AU705690B2 (en) *	1995-05-19	1999-05-27	Kyowa Hakko Kogyo Co. Ltd.	Oxygen-containing heterocyclic compounds

1999
- 1999-06-26 CA CA002336894A patent/CA2336894A1/en not_active Abandoned
- 1999-06-26 ZA ZA200100088A patent/ZA200100088B/en unknown
- 1999-06-26 WO PCT/EP1999/004451 patent/WO2000001695A1/en not_active Ceased
- 1999-06-26 SI SI9930588T patent/SI1095040T1/xx unknown
- 1999-06-26 AU AU47786/99A patent/AU761647B2/en not_active Ceased
- 1999-06-26 DE DE69916066T patent/DE69916066T2/de not_active Expired - Fee Related
- 1999-06-26 IL IL14046899A patent/IL140468A0/xx not_active IP Right Cessation
- 1999-06-26 PT PT99931198T patent/PT1095040E/pt unknown
- 1999-06-26 ES ES99931198T patent/ES2219031T3/es not_active Expired - Lifetime
- 1999-06-26 US US09/720,812 patent/US6376485B1/en not_active Expired - Fee Related
- 1999-06-26 DK DK99931198T patent/DK1095040T3/da active
- 1999-06-26 JP JP2000558098A patent/JP2002519423A/ja not_active Withdrawn
- 1999-06-26 AT AT99931198T patent/ATE263166T1/de not_active IP Right Cessation
- 1999-06-26 EP EP99931198A patent/EP1095040B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU4778699A (en)	2000-01-24
US6376485B1 (en)	2002-04-23
PT1095040E (pt)	2004-08-31
DE69916066T2 (de)	2005-02-24
ZA200100088B (en)	2002-05-06
WO2000001695A1 (en)	2000-01-13
DE69916066D1 (de)	2004-05-06
CA2336894A1 (en)	2000-01-13
JP2002519423A (ja)	2002-07-02
ATE263166T1 (de)	2004-04-15
EP1095040A1 (de)	2001-05-02
SI1095040T1 (en)	2004-10-31
AU761647B2 (en)	2003-06-05
ES2219031T3 (es)	2004-11-16
DK1095040T3 (da)	2004-07-26
EP1095040B1 (de)	2004-03-31

Legal Events

Date	Code	Title
2005-05-17	FF	Patent granted
2005-09-25	KB	Patent renewed
2010-10-31	MM9K	Patent not in force due to non-payment of renewal fees

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