IL147575A - Method for purifying keratinocyte growth factors - Google Patents

Method for purifying keratinocyte growth factors

Info

Publication number
IL147575A
IL147575A IL14757595A IL14757595A IL147575A IL 147575 A IL147575 A IL 147575A IL 14757595 A IL14757595 A IL 14757595A IL 14757595 A IL14757595 A IL 14757595A IL 147575 A IL147575 A IL 147575A
Authority
IL
Israel
Prior art keywords
kgf
seq
solution
oxidized
cation exchange
Prior art date
Application number
IL14757595A
Other languages
English (en)
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/487,830 external-priority patent/US6008328A/en
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of IL147575A publication Critical patent/IL147575A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14757595A 1994-10-13 1995-10-12 Method for purifying keratinocyte growth factors IL147575A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32333994A 1994-10-13 1994-10-13
US08/487,830 US6008328A (en) 1994-10-13 1995-06-07 Method for purifying keratinocyte growth factors
IL11560595A IL115605A (en) 1994-10-13 1995-10-12 Method for purifying keratinocyte growth factors

Publications (1)

Publication Number Publication Date
IL147575A true IL147575A (en) 2004-05-12

Family

ID=26983902

Family Applications (3)

Application Number Title Priority Date Filing Date
IL14757595A IL147575A (en) 1994-10-13 1995-10-12 Method for purifying keratinocyte growth factors
IL11560595A IL115605A (en) 1994-10-13 1995-10-12 Method for purifying keratinocyte growth factors
IL14757502A IL147575A0 (en) 1994-10-13 2002-01-10 Method for purifying keratinocyte growth factors

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL11560595A IL115605A (en) 1994-10-13 1995-10-12 Method for purifying keratinocyte growth factors
IL14757502A IL147575A0 (en) 1994-10-13 2002-01-10 Method for purifying keratinocyte growth factors

Country Status (18)

Country Link
EP (2) EP0785949B1 (fr)
JP (1) JP3877226B2 (fr)
CN (1) CN1161380C (fr)
AT (1) ATE239038T1 (fr)
CA (1) CA2201762C (fr)
CZ (1) CZ98297A3 (fr)
DE (2) DE122006000019I1 (fr)
DK (1) DK0785949T3 (fr)
ES (1) ES2197926T3 (fr)
HU (1) HU220584B1 (fr)
IL (3) IL147575A (fr)
LU (1) LU91235I2 (fr)
NL (1) NL300229I2 (fr)
NO (1) NO971567L (fr)
PT (1) PT785949E (fr)
SI (1) SI0785949T1 (fr)
SK (1) SK43097A3 (fr)
WO (1) WO1996011952A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7232667B2 (en) 1995-02-14 2007-06-19 Human Genome Sciences, Inc. Keratinocyte growth factor-2 polynucleotides
US6077692A (en) * 1995-02-14 2000-06-20 Human Genome Sciences, Inc. Keratinocyte growth factor-2
US6693077B1 (en) 1995-02-14 2004-02-17 Human Genome Sciences, Inc. Keratinocyte growth factor-2
US6743422B1 (en) 1996-10-15 2004-06-01 Amgen, Inc. Keratinocyte growth factor-2 products
AU1905799A (en) 1997-12-22 1999-07-12 Human Genome Sciences, Inc. Keratinocyte growth factor-2 formulations
US6869927B1 (en) 1997-12-22 2005-03-22 Human Genome Sciences, Inc. Keratinocyte growth factor-2 formulations
JP2004526437A (ja) * 2001-02-06 2004-09-02 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 低減された免疫原性を有する修飾されたケラチノサイト成長因子(kgf)
AU2002326742B2 (en) * 2001-08-21 2007-05-31 Novartis Vaccines And Diagnostics, Inc. KGF polypeptide compositions
CN102242124B (zh) * 2010-05-10 2013-05-22 齐鲁制药有限公司 改造的角化细胞生长因子基因及其在酵母中的表达
CN102675449B (zh) * 2011-03-17 2016-06-08 重庆富进生物医药有限公司 缺失型人角质细胞生长因子-ⅰ二硫键变构体及其用途
CN109402130A (zh) * 2018-11-23 2019-03-01 成都中医药大学附属医院 一种重组人角质细胞生长因子-1及其制备方法和用途
CN110183529B (zh) * 2019-05-23 2023-06-02 重庆派金生物科技有限公司 一种缺失型人角质细胞生长因子-1的重组制备方法
KR20230127721A (ko) 2022-02-25 2023-09-01 한국해양과학기술원 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990008771A1 (fr) * 1989-01-31 1990-08-09 Rubin Jeffrey S Adn codant un facteur de croissance specifique contre des cellules epitheliales
WO1992011360A1 (fr) * 1990-12-18 1992-07-09 Amgen Inc. Analogues du facteur de croissance acide des fibroblastes presentant une stabilite et une activite biologique ameliorees
DE69434053T2 (de) * 1993-06-29 2006-02-23 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Verkürzter keratinocytenwachstumsfaktor(kgf)mit erhöhter biologischer aktivität
CA2172137C (fr) * 1993-09-24 1999-12-14 Andrew Peter Seddon Analogues structurels de facteurs de croissance des fibroblastes, avec sequence en boucle
PT785950E (pt) * 1994-10-13 2003-09-30 Amgen Inc Analogos do factor de crescimento de queratinocitos
EP0786000A1 (fr) * 1994-10-13 1997-07-30 Amgen Inc. Analogues de facteur de croissance du fibroblaste acide a stabilite et activite biologique renforcees
KR100278597B1 (ko) * 1994-10-13 2001-01-15 스티븐 엠. 오드리 케라티노사이트 성장 인자의 유사체, 이 유사체를 암호하는 핵산 및 그것의 제조방법

Also Published As

Publication number Publication date
NO971567L (no) 1997-06-12
DK0785949T3 (da) 2003-08-18
IL115605A (en) 2003-06-24
NO971567D0 (no) 1997-04-04
HU220584B1 (hu) 2002-03-28
IL115605A0 (en) 1996-01-19
PT785949E (pt) 2003-09-30
AU3830695A (en) 1996-05-06
DE69530599D1 (de) 2003-06-05
CN1169734A (zh) 1998-01-07
IL147575A0 (en) 2002-08-14
CZ98297A3 (cs) 1998-08-12
NL300229I2 (nl) 2006-09-01
WO1996011952A1 (fr) 1996-04-25
ATE239038T1 (de) 2003-05-15
CA2201762C (fr) 2001-12-18
EP1334981A2 (fr) 2003-08-13
NL300229I1 (nl) 2006-06-01
AU709362B2 (en) 1999-08-26
DE122006000019I1 (de) 2006-06-29
JP3877226B2 (ja) 2007-02-07
EP1334981A3 (fr) 2004-05-06
SI0785949T1 (en) 2003-08-31
LU91235I2 (fr) 2006-11-22
EP1334981B1 (fr) 2011-01-26
JPH10507452A (ja) 1998-07-21
EP0785949B1 (fr) 2003-05-02
DE69530599T2 (de) 2003-11-13
HUT76879A (en) 1997-12-29
CN1161380C (zh) 2004-08-11
SK43097A3 (en) 1998-10-07
EP0785949A1 (fr) 1997-07-30
MX9702481A (es) 1997-07-31
ES2197926T3 (es) 2004-01-16
CA2201762A1 (fr) 1996-04-25

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