IL149889A0 - Heparanase-like proteins and nucleotides encoding them - Google Patents
Heparanase-like proteins and nucleotides encoding themInfo
- Publication number
- IL149889A0 IL149889A0 IL14988900A IL14988900A IL149889A0 IL 149889 A0 IL149889 A0 IL 149889A0 IL 14988900 A IL14988900 A IL 14988900A IL 14988900 A IL14988900 A IL 14988900A IL 149889 A0 IL149889 A0 IL 149889A0
- Authority
- IL
- Israel
- Prior art keywords
- heparanase
- proteins
- nucleotides encoding
- present
- nucleotides
- Prior art date
Links
- 239000002773 nucleotide Substances 0.000 title 1
- 125000003729 nucleotide group Chemical group 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 102100024025 Heparanase Human genes 0.000 abstract 1
- 108010037536 heparanase Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01166—Heparanase (3.2.1.166)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9930392.7A GB9930392D0 (en) | 1999-12-22 | 1999-12-22 | Substances |
| GB0008713A GB0008713D0 (en) | 2000-04-07 | 2000-04-07 | Substances |
| PCT/GB2000/004963 WO2001046392A2 (en) | 1999-12-22 | 2000-12-21 | Homologues of human heparanase and splice variants thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL149889A0 true IL149889A0 (en) | 2002-11-10 |
Family
ID=26244068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14988900A IL149889A0 (en) | 1999-12-22 | 2000-12-21 | Heparanase-like proteins and nucleotides encoding them |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7273744B2 (es) |
| EP (1) | EP1240313B1 (es) |
| JP (1) | JP2003517835A (es) |
| AT (1) | ATE334194T1 (es) |
| AU (1) | AU2207801A (es) |
| CA (1) | CA2393855A1 (es) |
| DE (1) | DE60029624T2 (es) |
| DK (1) | DK1240313T3 (es) |
| ES (1) | ES2269211T3 (es) |
| IL (1) | IL149889A0 (es) |
| WO (1) | WO2001046392A2 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5033101A (en) * | 2000-02-24 | 2001-10-08 | Bayer Aktiengesellschaft | Regulation of human heparanase-like enzyme |
| GB0008912D0 (en) * | 2000-04-11 | 2000-05-31 | Janssen Pharmaceutica Nv | Mammalian heparanase |
| AU2001251278A1 (en) * | 2000-04-20 | 2001-11-07 | Pharmacia And Upjohn Company | Heparanase ii, a human heparanase paralog |
| AU2001287610A1 (en) * | 2000-07-12 | 2002-01-21 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | A second human heparanase, and splice variants thereof, with a predominant expression in skeletal muscle, heart and pancreas |
| EP1385990A4 (en) * | 2001-05-09 | 2004-09-22 | Insight Biopharmaceuticals Ltd | METHODS AND MATERIALS USING HEPARANASE AS A DIAGNOSTIC MARKER FOR HEMOSTATIC DISORDERS |
| PT1786908E (pt) * | 2004-08-18 | 2010-04-29 | Bayer Cropscience Ag | Plantas com um aumento da actividade da enzima de fosforilação do amido r3 nos plastídeos |
| EP1968379A2 (en) * | 2005-12-12 | 2008-09-17 | Riolan Technologies, Inc. | Compositions, methods and kits for removing debris from an ocular area |
| US20200087390A1 (en) | 2016-12-21 | 2020-03-19 | Amgen Inc. | Anti-tnf alpha antibody formulations |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL79255A0 (en) | 1986-06-26 | 1986-09-30 | Hadassah Med Org | Composition for metastasis prevention |
| WO1995013830A1 (en) | 1993-11-17 | 1995-05-26 | Massachusetts Institute Of Technology | Method for inhibiting angiogenesis using heparinase |
| ATE273020T1 (de) | 1995-09-29 | 2004-08-15 | Biomarin Pharm Inc | Verwendung von heparinasen zur verminderung von entzündungsreaktionen |
| US5968822A (en) | 1997-09-02 | 1999-10-19 | Pecker; Iris | Polynucleotide encoding a polypeptide having heparanase activity and expression of same in transduced cells |
| JP2002510462A (ja) * | 1997-10-28 | 2002-04-09 | ジ・オーストラリアン・ナショナル・ユニバーシティー | 哺乳類のエンドグルクロニダーゼをコードする単離された核酸分子およびその使用 |
| GB9802725D0 (en) | 1998-02-09 | 1998-04-08 | Ciba Geigy Ag | Organic compounds |
| US6387643B1 (en) | 1998-02-24 | 2002-05-14 | Pharmacia And Upjohn Company | Human platelet heparanase polypeptides, polynucleotide molecules that encode them, and methods for the identification of compounds that alter heparanase activity |
| EP1212341A4 (en) * | 1999-06-25 | 2002-11-27 | Insight Strategy & Marketing | POLYNUCLEOTIDES AND CODED POLYPEPTIDES ARE THE REMOTE HOMOLOGY OF HEPARANASE |
| US7101706B1 (en) * | 1999-06-25 | 2006-09-05 | Insight Biopharmaceuticals Ltd. | Polynucleotides and polypeptides encoded thereby distantly homologous to heparanase |
| WO2001021814A1 (en) * | 1999-09-23 | 2001-03-29 | Merck Patent Gmbh | Heparanase-2, a member of the heparanase protein family |
| WO2001079253A1 (en) * | 2000-04-18 | 2001-10-25 | Human Genome Sciences, Inc. | Extracellular matrix polynucleotides, polypeptides, and antibodies |
-
2000
- 2000-12-21 EP EP00985677A patent/EP1240313B1/en not_active Expired - Lifetime
- 2000-12-21 DK DK00985677T patent/DK1240313T3/da active
- 2000-12-21 JP JP2001546890A patent/JP2003517835A/ja active Pending
- 2000-12-21 CA CA002393855A patent/CA2393855A1/en not_active Abandoned
- 2000-12-21 WO PCT/GB2000/004963 patent/WO2001046392A2/en not_active Ceased
- 2000-12-21 IL IL14988900A patent/IL149889A0/xx unknown
- 2000-12-21 DE DE60029624T patent/DE60029624T2/de not_active Expired - Lifetime
- 2000-12-21 AU AU22078/01A patent/AU2207801A/en not_active Abandoned
- 2000-12-21 AT AT00985677T patent/ATE334194T1/de not_active IP Right Cessation
- 2000-12-21 ES ES00985677T patent/ES2269211T3/es not_active Expired - Lifetime
-
2002
- 2002-06-21 US US10/177,245 patent/US7273744B2/en not_active Expired - Fee Related
-
2007
- 2007-08-14 US US11/893,095 patent/US20090246201A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60029624T2 (de) | 2007-08-09 |
| JP2003517835A (ja) | 2003-06-03 |
| US20030083254A1 (en) | 2003-05-01 |
| DE60029624D1 (de) | 2006-09-07 |
| CA2393855A1 (en) | 2001-06-28 |
| EP1240313B1 (en) | 2006-07-26 |
| ES2269211T3 (es) | 2007-04-01 |
| EP1240313A2 (en) | 2002-09-18 |
| US20090246201A1 (en) | 2009-10-01 |
| WO2001046392A3 (en) | 2001-12-06 |
| AU2207801A (en) | 2001-07-03 |
| ATE334194T1 (de) | 2006-08-15 |
| US7273744B2 (en) | 2007-09-25 |
| WO2001046392A2 (en) | 2001-06-28 |
| DK1240313T3 (da) | 2006-11-27 |
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