IL150486A0 - Pyrimidine carboxamides useful as inhibitors of pde4 isozymes - Google Patents

Pyrimidine carboxamides useful as inhibitors of pde4 isozymes

Info

Publication number
IL150486A0
IL150486A0 IL15048601A IL15048601A IL150486A0 IL 150486 A0 IL150486 A0 IL 150486A0 IL 15048601 A IL15048601 A IL 15048601A IL 15048601 A IL15048601 A IL 15048601A IL 150486 A0 IL150486 A0 IL 150486A0
Authority
IL
Israel
Prior art keywords
inhibitors
pde4 isozymes
carboxamides useful
pyrimidine carboxamides
pyrimidine
Prior art date
Application number
IL15048601A
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of IL150486A0 publication Critical patent/IL150486A0/xx

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
IL15048601A 2000-01-31 2001-01-30 Pyrimidine carboxamides useful as inhibitors of pde4 isozymes IL150486A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17928200P 2000-01-31 2000-01-31
PCT/IB2001/000125 WO2001057025A1 (fr) 2000-01-31 2001-01-30 Carboxamides de pyrimidine utilises comme inhibiteurs des isozymes pde4

Publications (1)

Publication Number Publication Date
IL150486A0 true IL150486A0 (en) 2002-12-01

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Application Number Title Priority Date Filing Date
IL15048601A IL150486A0 (en) 2000-01-31 2001-01-30 Pyrimidine carboxamides useful as inhibitors of pde4 isozymes

Country Status (45)

Country Link
US (1) US6740655B2 (fr)
EP (1) EP1252157B1 (fr)
JP (1) JP2003522165A (fr)
KR (1) KR20020071029A (fr)
CN (1) CN1404480A (fr)
AP (1) AP2002002590A0 (fr)
AR (1) AR027336A1 (fr)
AT (1) ATE269860T1 (fr)
AU (1) AU2700301A (fr)
BG (1) BG106868A (fr)
BR (1) BR0107934A (fr)
CA (1) CA2396458C (fr)
CO (1) CO5271669A1 (fr)
CR (1) CR6714A (fr)
CZ (1) CZ20022413A3 (fr)
DE (1) DE60103976T2 (fr)
DK (1) DK1252157T3 (fr)
DZ (1) DZ3406A1 (fr)
EA (1) EA005028B1 (fr)
EE (1) EE200200426A (fr)
ES (1) ES2223772T3 (fr)
GE (1) GEP20043385B (fr)
GT (1) GT200100023A (fr)
HK (1) HK1054232A1 (fr)
HN (1) HN2001000018A (fr)
HU (1) HUP0204271A3 (fr)
IL (1) IL150486A0 (fr)
IS (1) IS6444A (fr)
MA (1) MA26871A1 (fr)
MX (1) MXPA02007465A (fr)
NO (1) NO20023614L (fr)
NZ (1) NZ519726A (fr)
OA (1) OA12170A (fr)
PA (1) PA8511301A1 (fr)
PE (1) PE20011059A1 (fr)
PL (1) PL357555A1 (fr)
PT (1) PT1252157E (fr)
PY (1) PY0102108A (fr)
SK (1) SK10342002A3 (fr)
SV (1) SV2001000298A (fr)
TN (1) TNSN01019A1 (fr)
TR (1) TR200402292T4 (fr)
UY (1) UY26570A1 (fr)
WO (1) WO2001057025A1 (fr)
ZA (1) ZA200206034B (fr)

Families Citing this family (86)

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ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
EP1248597B1 (fr) * 1999-12-24 2005-03-30 Glaxo Group Limited Formulation pharmaceutique en aerosol de salmeterol et de propionate de fluticasone
DE10110772A1 (de) * 2001-03-07 2002-09-12 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und PDE-IV-Inhibitoren
US7776315B2 (en) 2000-10-31 2010-08-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and additional active ingredients
YU39503A (sh) * 2000-11-22 2006-05-25 F. Hoffmann-La Roche Ag. Derivati pirimidina
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