IL153637A0 - Aminoalkenylbenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same - Google Patents
Aminoalkenylbenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing sameInfo
- Publication number
- IL153637A0 IL153637A0 IL15363701A IL15363701A IL153637A0 IL 153637 A0 IL153637 A0 IL 153637A0 IL 15363701 A IL15363701 A IL 15363701A IL 15363701 A IL15363701 A IL 15363701A IL 153637 A0 IL153637 A0 IL 153637A0
- Authority
- IL
- Israel
- Prior art keywords
- same
- benzofuran
- aminoalkenylbenzoyl
- compositions containing
- benzothiophene derivatives
- Prior art date
Links
- FCEHBMOGCRZNNI-UHFFFAOYSA-N 1-benzothiophene Chemical class C1=CC=C2SC=CC2=C1 FCEHBMOGCRZNNI-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- IANQTJSKSUMEQM-UHFFFAOYSA-N 1-benzofuran Chemical compound C1=CC=C2OC=CC2=C1 IANQTJSKSUMEQM-UHFFFAOYSA-N 0.000 abstract 2
- 210000000748 cardiovascular system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0010835A FR2813307B1 (fr) | 2000-08-23 | 2000-08-23 | Aminoalkenylbenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant |
| PCT/FR2001/002656 WO2002016338A1 (fr) | 2000-08-23 | 2001-08-23 | Aminoalkenylbenzoyl-benzofuranes ou benzothiophenes, leur procede de preparation et les compositions les contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL153637A0 true IL153637A0 (en) | 2003-07-06 |
Family
ID=8853675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15363701A IL153637A0 (en) | 2000-08-23 | 2001-08-23 | Aminoalkenylbenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6946483B2 (de) |
| EP (1) | EP1315708B1 (de) |
| JP (1) | JP4918209B2 (de) |
| KR (1) | KR20030023768A (de) |
| CN (1) | CN1471519A (de) |
| AT (1) | ATE273293T1 (de) |
| AU (1) | AU2001284154A1 (de) |
| BG (1) | BG107553A (de) |
| BR (1) | BR0113350A (de) |
| CA (1) | CA2415846A1 (de) |
| CZ (1) | CZ2003520A3 (de) |
| DE (1) | DE60104866T2 (de) |
| EA (1) | EA200300063A1 (de) |
| FR (1) | FR2813307B1 (de) |
| HU (1) | HUP0302892A3 (de) |
| IL (1) | IL153637A0 (de) |
| IS (1) | IS6676A (de) |
| MA (1) | MA26944A1 (de) |
| MX (1) | MXPA03001592A (de) |
| NO (1) | NO20030801L (de) |
| OA (1) | OA12358A (de) |
| PL (1) | PL362123A1 (de) |
| SK (1) | SK2112003A3 (de) |
| WO (1) | WO2002016338A1 (de) |
| ZA (1) | ZA200300746B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA038195B1 (ru) | 2009-01-16 | 2021-07-22 | Экселиксис, Инк. | Малатная соль n-(4-{[6,7-бис-(метилокси)хинолин-4-ил]окси}фенил)-n'-(4-фторфенил)циклопропан-1,1-дикарбоксамида и ее применение для лечения рака почек и печени |
| AU2011202542A1 (en) | 2010-07-14 | 2012-02-02 | Indian Institute Of Science | Benzothiophene carboxamide compounds, composition and applications thereof |
| CN107857748B (zh) * | 2017-11-14 | 2020-06-02 | 沈阳药科大学 | 5-[2-羟基-3-(烷胺基)丙氧基]苯并呋喃类化合物及其应用 |
| CN107827849B (zh) * | 2017-11-14 | 2020-06-02 | 沈阳药科大学 | 6-[2-羟基-3-(烷胺基)丙氧基]苯并呋喃类化合物及其应用 |
| CN107935972B (zh) * | 2017-11-14 | 2020-06-02 | 沈阳药科大学 | 5-[2-羟基-3-(异丙胺基)丙氧基]苯并呋喃类衍生物及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3248401A (en) * | 1966-04-26 | Diethylaminoe hoxybenzoyl benzofurans | ||
| US4831054A (en) * | 1988-04-18 | 1989-05-16 | Taro Pharmaceuticals, Ltd. | 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia |
| AT391316B (de) * | 1988-09-15 | 1990-09-25 | Ebewe Arzneimittel | Neue thienyloxy-alkylamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| FR2665444B1 (fr) * | 1990-08-06 | 1992-11-27 | Sanofi Sa | Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant. |
| US5364880A (en) * | 1993-06-16 | 1994-11-15 | Advanced Therapies, Inc. | Compound for treatment of cardiac arrhythmia, synthesis, and methods of use |
| US6756388B1 (en) * | 1993-10-12 | 2004-06-29 | Pfizer Inc. | Benzothiophenes and related compounds as estrogen agonists |
| US5523309A (en) * | 1995-03-10 | 1996-06-04 | Eli Lilly And Company | Benzofuran pharmaceutical compounds |
| US5622974A (en) * | 1995-03-10 | 1997-04-22 | Eli Lilly And Company | α-substituted-3-benzyl-benzofurans |
| DK0842169T3 (da) * | 1995-06-26 | 2001-01-29 | Lilly Co Eli | Benzothiophenforbindelser |
| US5827876A (en) * | 1996-04-09 | 1998-10-27 | American Home Products Corporation | Inhibition of bone loss by 3-(4-acrylamidobenzoyl) benzo b!-thiophenes |
| AU3171099A (en) * | 1998-04-17 | 1999-11-08 | Senga Pharmaceutical Laboratory Inc. | 1-heteroindene derivatives and medicinal composition containing the same |
-
2000
- 2000-08-23 FR FR0010835A patent/FR2813307B1/fr not_active Expired - Fee Related
-
2001
- 2001-08-23 HU HU0302892A patent/HUP0302892A3/hu unknown
- 2001-08-23 CZ CZ2003520A patent/CZ2003520A3/cs unknown
- 2001-08-23 SK SK211-2003A patent/SK2112003A3/sk unknown
- 2001-08-23 AT AT01963120T patent/ATE273293T1/de not_active IP Right Cessation
- 2001-08-23 AU AU2001284154A patent/AU2001284154A1/en not_active Abandoned
- 2001-08-23 KR KR10-2003-7002619A patent/KR20030023768A/ko not_active Withdrawn
- 2001-08-23 IL IL15363701A patent/IL153637A0/xx unknown
- 2001-08-23 EP EP01963120A patent/EP1315708B1/de not_active Expired - Lifetime
- 2001-08-23 US US10/362,291 patent/US6946483B2/en not_active Expired - Lifetime
- 2001-08-23 DE DE60104866T patent/DE60104866T2/de not_active Expired - Lifetime
- 2001-08-23 JP JP2002521439A patent/JP4918209B2/ja not_active Expired - Fee Related
- 2001-08-23 BR BR0113350-0A patent/BR0113350A/pt not_active IP Right Cessation
- 2001-08-23 PL PL01362123A patent/PL362123A1/xx not_active Application Discontinuation
- 2001-08-23 CA CA002415846A patent/CA2415846A1/fr not_active Abandoned
- 2001-08-23 EA EA200300063A patent/EA200300063A1/ru unknown
- 2001-08-23 OA OA1200300034A patent/OA12358A/fr unknown
- 2001-08-23 MX MXPA03001592A patent/MXPA03001592A/es not_active Application Discontinuation
- 2001-08-23 CN CNA018177654A patent/CN1471519A/zh active Pending
- 2001-08-23 WO PCT/FR2001/002656 patent/WO2002016338A1/fr not_active Ceased
-
2003
- 2003-01-13 IS IS6676A patent/IS6676A/is unknown
- 2003-01-28 ZA ZA200300746A patent/ZA200300746B/xx unknown
- 2003-02-13 BG BG107553A patent/BG107553A/xx unknown
- 2003-02-17 MA MA27043A patent/MA26944A1/fr unknown
- 2003-02-20 NO NO20030801A patent/NO20030801L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004506726A (ja) | 2004-03-04 |
| FR2813307B1 (fr) | 2002-11-08 |
| AU2001284154A1 (en) | 2002-03-04 |
| JP4918209B2 (ja) | 2012-04-18 |
| IS6676A (is) | 2003-01-13 |
| EA200300063A1 (ru) | 2003-08-28 |
| US20030187060A1 (en) | 2003-10-02 |
| OA12358A (fr) | 2006-05-16 |
| BG107553A (en) | 2004-01-30 |
| DE60104866D1 (de) | 2004-09-16 |
| HUP0302892A2 (hu) | 2003-12-29 |
| NO20030801D0 (no) | 2003-02-20 |
| PL362123A1 (en) | 2004-10-18 |
| ZA200300746B (en) | 2004-02-10 |
| EP1315708B1 (de) | 2004-08-11 |
| BR0113350A (pt) | 2003-07-08 |
| CA2415846A1 (fr) | 2002-02-28 |
| ATE273293T1 (de) | 2004-08-15 |
| FR2813307A1 (fr) | 2002-03-01 |
| SK2112003A3 (en) | 2003-08-05 |
| CZ2003520A3 (cs) | 2003-05-14 |
| MXPA03001592A (es) | 2003-09-10 |
| WO2002016338A1 (fr) | 2002-02-28 |
| MA26944A1 (fr) | 2004-12-20 |
| US6946483B2 (en) | 2005-09-20 |
| WO2002016338A8 (fr) | 2002-05-10 |
| HUP0302892A3 (en) | 2005-02-28 |
| KR20030023768A (ko) | 2003-03-19 |
| NO20030801L (no) | 2003-04-23 |
| EP1315708A1 (de) | 2003-06-04 |
| CN1471519A (zh) | 2004-01-28 |
| DE60104866T2 (de) | 2005-10-20 |
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