IL155538A0 - Inhalative solution formulation containing a tiotropium salt - Google Patents

Inhalative solution formulation containing a tiotropium salt

Info

Publication number: IL155538A0
Authority: IL; Israel
Prior art keywords: formulation containing; solution formulation; tiotropium salt; inhalative solution; inhalative
Prior art date: 2000-10-31

Application number

IL15553801A

Other languages

English (en)

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-31

Filing date

2001-10-24

Publication date

2003-11-23

2001-10-24 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2003-11-23 Publication of IL155538A0 publication Critical patent/IL155538A0/xx

Links

238000009472 formulation Methods 0.000 title 1
239000000203 mixture Substances 0.000 title 1
LERNTVKEWCAPOY-DZZGSBJMSA-N tiotropium Chemical class O([C@H]1C[C@@H]2[N+]([C@H](C1)[C@@H]1[C@H]2O1)(C)C)C(=O)C(O)(C=1SC=CC=1)C1=CC=CS1 LERNTVKEWCAPOY-DZZGSBJMSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/537—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Pulmonology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Dispersion Chemistry (AREA)
Otolaryngology (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Cosmetics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IL15553801A 2000-10-31 2001-10-24 Inhalative solution formulation containing a tiotropium salt IL155538A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10054036		2000-10-31
PCT/EP2001/012292 WO2002036104A2 (de)	2000-10-31	2001-10-24	Inhalative lösungsformulierung mit einem tiotropiumsalz

Publications (1)

Publication Number	Publication Date
IL155538A0 true IL155538A0 (en)	2003-11-23

Family

ID=7661723

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL15553801A IL155538A0 (en)	2000-10-31	2001-10-24	Inhalative solution formulation containing a tiotropium salt
IL155538A IL155538A (en)	2000-10-31	2003-04-21	Inhalative solution formulation containing a tiotropium salt

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL155538A IL155538A (en)	2000-10-31	2003-04-21	Inhalative solution formulation containing a tiotropium salt

Country Status (38)

Country	Link
EP (2)	EP1333819B1 (cs)
JP (1)	JP4344135B2 (cs)
KR (1)	KR100853107B1 (cs)
CN (2)	CN101292964A (cs)
AR (1)	AR038764A1 (cs)
AT (1)	ATE373473T1 (cs)
AU (2)	AU2173802A (cs)
BG (1)	BG66315B1 (cs)
BR (1)	BRPI0115076B8 (cs)
CA (1)	CA2426074C (cs)
CY (1)	CY1107825T1 (cs)
CZ (1)	CZ300794B6 (cs)
DE (2)	DE10152521A1 (cs)
DK (1)	DK1333819T3 (cs)
EA (1)	EA007604B1 (cs)
EC (1)	ECSP034541A (cs)
EE (1)	EE05314B1 (cs)
ES (1)	ES2294045T3 (cs)
HR (1)	HRP20030338B1 (cs)
HU (1)	HU229411B1 (cs)
IL (2)	IL155538A0 (cs)
ME (1)	ME00244B (cs)
MX (1)	MXPA03003742A (cs)
MY (1)	MY138940A (cs)
NO (1)	NO332519B1 (cs)
NZ (1)	NZ526023A (cs)
PE (1)	PE20030092A1 (cs)
PL (1)	PL203316B1 (cs)
PT (1)	PT1333819E (cs)
RS (1)	RS50859B (cs)
SA (1)	SA01220482B1 (cs)
SI (1)	SI1333819T1 (cs)
SK (1)	SK286027B6 (cs)
TW (1)	TWI293885B (cs)
UA (1)	UA78690C2 (cs)
UY (1)	UY26989A1 (cs)
WO (1)	WO2002036104A2 (cs)
ZA (1)	ZA200302922B (cs)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10216036A1 (de) *	2002-04-11	2003-10-23	Boehringer Ingelheim Pharma	Aerosolformulierung für die Inhalation enthaltend ein Tiotropiumsalz
CN1292748C (zh) *	2003-03-05	2007-01-03	南昌弘益科技有限公司	噻托溴铵吸入粉雾剂及其制备工艺
UY28590A1 (es) *	2003-11-03	2005-06-30	Boehringer Ingelheim Int	Procedimiento para la preparación de nuevas sales de tiotropio, nuevas sales de tiotropio como tales, así como las formulaciones medicamentosas que las contienen.
EP2083007B1 (de) *	2003-11-03	2013-04-24	Boehringer Ingelheim International Gmbh	Tiotropiumsalze, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittelformulierungen
JP5227790B2 (ja)	2005-05-02	2013-07-03	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	新規結晶性臭化チオトロピウム
EP2044967A1 (de) *	2007-10-01	2009-04-08	Boehringer Ingelheim Pharma GmbH & Co. KG	Zerstäuber
CN104306361A (zh) *	2014-09-24	2015-01-28	万特制药(海南)有限公司	一种含噻托溴铵的吸入性溶液
CN111374963A (zh) *	2018-12-31	2020-07-07	天津药业研究院有限公司	一种用于吸入的噻托铵溶液剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3931041C2 (de) *	1989-09-16	2000-04-06	Boehringer Ingelheim Kg	Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
SG45171A1 (en) *	1990-03-21	1998-01-16	Boehringer Ingelheim Int	Atomising devices and methods
DE19536902A1 (de) *	1995-10-04	1997-04-10	Boehringer Ingelheim Int	Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
DE19653969A1 (de) *	1996-12-20	1998-06-25	Boehringer Ingelheim Kg	Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
DE19847968A1 (de) *	1998-10-17	2000-04-20	Boehringer Ingelheim Pharma	Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen

2001
- 2001-10-24 CN CNA2008100985489A patent/CN101292964A/zh active Pending
- 2001-10-24 EA EA200300482A patent/EA007604B1/ru not_active IP Right Cessation
- 2001-10-24 ES ES01992567T patent/ES2294045T3/es not_active Expired - Lifetime
- 2001-10-24 RS YUP-330/03A patent/RS50859B/sr unknown
- 2001-10-24 KR KR1020037006013A patent/KR100853107B1/ko not_active Expired - Lifetime
- 2001-10-24 CA CA002426074A patent/CA2426074C/en not_active Expired - Fee Related
- 2001-10-24 WO PCT/EP2001/012292 patent/WO2002036104A2/de not_active Ceased
- 2001-10-24 DE DE10152521A patent/DE10152521A1/de not_active Withdrawn
- 2001-10-24 AU AU2173802A patent/AU2173802A/xx active Pending
- 2001-10-24 HU HU0301378A patent/HU229411B1/hu unknown
- 2001-10-24 IL IL15553801A patent/IL155538A0/xx active IP Right Grant
- 2001-10-24 MX MXPA03003742A patent/MXPA03003742A/es active IP Right Grant
- 2001-10-24 EP EP01992567A patent/EP1333819B1/de not_active Expired - Lifetime
- 2001-10-24 SK SK527-2003A patent/SK286027B6/sk not_active IP Right Cessation
- 2001-10-24 CZ CZ20031486A patent/CZ300794B6/cs unknown
- 2001-10-24 DK DK01992567T patent/DK1333819T3/da active
- 2001-10-24 NZ NZ526023A patent/NZ526023A/en not_active IP Right Cessation
- 2001-10-24 PT PT01992567T patent/PT1333819E/pt unknown
- 2001-10-24 EE EEP200300203A patent/EE05314B1/xx unknown
- 2001-10-24 EP EP07111499A patent/EP1837021A3/de not_active Withdrawn
- 2001-10-24 AU AU2002221738A patent/AU2002221738B2/en not_active Expired
- 2001-10-24 DE DE50113037T patent/DE50113037D1/de not_active Expired - Lifetime
- 2001-10-24 HR HR20030338A patent/HRP20030338B1/xx not_active IP Right Cessation
- 2001-10-24 ME MEP-2008-404A patent/ME00244B/me unknown
- 2001-10-24 CN CNB018183158A patent/CN100396285C/zh not_active Expired - Lifetime
- 2001-10-24 BR BRPI0115076A patent/BRPI0115076B8/pt not_active IP Right Cessation
- 2001-10-24 PL PL360405A patent/PL203316B1/pl unknown
- 2001-10-24 UA UA2003054959A patent/UA78690C2/uk unknown
- 2001-10-24 AT AT01992567T patent/ATE373473T1/de active
- 2001-10-24 SI SI200130774T patent/SI1333819T1/sl unknown
- 2001-10-24 JP JP2002538916A patent/JP4344135B2/ja not_active Expired - Lifetime
- 2001-10-28 SA SA01220482A patent/SA01220482B1/ar unknown
- 2001-10-29 TW TW090126764A patent/TWI293885B/zh active
- 2001-10-29 UY UY26989A patent/UY26989A1/es not_active Application Discontinuation
- 2001-10-29 MY MYPI20015000A patent/MY138940A/en unknown
- 2001-10-31 AR ARP010105087A patent/AR038764A1/es not_active Application Discontinuation
- 2001-10-31 PE PE2001001086A patent/PE20030092A1/es not_active Application Discontinuation
2003
- 2003-04-07 EC EC2003004541A patent/ECSP034541A/es unknown
- 2003-04-14 ZA ZA200302922A patent/ZA200302922B/en unknown
- 2003-04-16 BG BG107727A patent/BG66315B1/bg unknown
- 2003-04-21 IL IL155538A patent/IL155538A/en unknown
- 2003-04-29 NO NO20031911A patent/NO332519B1/no not_active IP Right Cessation
2007
- 2007-12-07 CY CY20071101562T patent/CY1107825T1/el unknown

Also Published As

Publication number	Publication date
ES2294045T3 (es)	2008-04-01
RS50859B (sr)	2010-08-31
PT1333819E (pt)	2007-10-29
AU2002221738B2 (en)	2007-01-11
JP2004512357A (ja)	2004-04-22
BR0115076A (pt)	2003-07-29
PL360405A1 (en)	2004-09-06
KR20030060926A (ko)	2003-07-16
CZ20031486A3 (cs)	2003-08-13
CY1107825T1 (el)	2013-06-19
CZ300794B6 (cs)	2009-08-12
UA78690C2 (uk)	2007-04-25
PE20030092A1 (es)	2003-03-24
MY138940A (en)	2009-08-28
AR038764A1 (es)	2005-01-26
UY26989A1 (es)	2002-06-20
HRP20030338A2 (en)	2005-04-30
SK5272003A3 (en)	2003-10-07
DE50113037D1 (de)	2007-10-31
EP1333819A2 (de)	2003-08-13
EE200300203A (et)	2003-10-15
HRP20030338B1 (en)	2011-09-30
DE10152521A1 (de)	2002-07-11
EP1837021A2 (de)	2007-09-26
MXPA03003742A (es)	2004-10-15
YU33003A (sh)	2006-05-25
HK1060524A1 (zh)	2004-08-13
BG66315B1 (bg)	2013-04-30
BRPI0115076B1 (pt)	2016-07-26
CA2426074A1 (en)	2002-05-10
NO332519B1 (no)	2012-10-08
HUP0301378A2 (hu)	2003-10-28
TWI293885B (en)	2008-03-01
WO2002036104A3 (de)	2002-08-01
SA01220482B1 (ar)	2007-07-31
HU229411B1 (en)	2013-12-30
BRPI0115076B8 (pt)	2021-05-25
SI1333819T1 (sl)	2007-12-31
CN101292964A (zh)	2008-10-29
EA200300482A1 (ru)	2003-12-25
CN100396285C (zh)	2008-06-25
ATE373473T1 (de)	2007-10-15
EP1333819B1 (de)	2007-09-19
EE05314B1 (et)	2010-08-16
BG107727A (bg)	2004-11-30
NO20031911L (no)	2003-04-29
EP1837021A3 (de)	2008-03-19
ECSP034541A (es)	2003-05-26
CA2426074C (en)	2008-12-23
JP4344135B2 (ja)	2009-10-14
NO20031911D0 (no)	2003-04-29
MEP40408A (en)	2011-02-10
AU2173802A (en)	2002-05-15
SK286027B6 (sk)	2008-01-07
PL203316B1 (pl)	2009-09-30
ME00244B (me)	2011-05-10
IL155538A (en)	2008-11-26
CN1473038A (zh)	2004-02-04
EA007604B1 (ru)	2006-12-29
DK1333819T3 (da)	2007-12-03
HUP0301378A3 (en)	2005-12-28
ZA200302922B (en)	2004-04-22
NZ526023A (en)	2005-05-27
WO2002036104A2 (de)	2002-05-10
KR100853107B1 (ko)	2008-08-21

Legal Events

Date	Code	Title	Description
2009-09-15	FF	Patent granted
2009-09-15	KB	Patent renewed

Publication	Publication Date	Title
IL147553A0 (en)	2002-08-14	Moxifloxacin formulation containing common salt
EG24139A (en)	2008-08-06	New inhalable powder containing tiotropium
EG24478A (en)	2009-08-03	New inhalable powder containing tiotropium
EG24669A (en)	2010-04-11	Antivral azaindole derivatives
IL153882A0 (en)	2003-07-31	Valsartan salts
EG24137A (en)	2008-08-06	Tropane derivatives useful in therapy
PL364223A1 (en)	2004-12-13	Pharmaceutical salts
PL358020A1 (en)	2004-08-09	Novel use for complex fluorides
IL155676A0 (en)	2003-11-23	Inhalative solution formulation containing a tiotropium salt
GB0011807D0 (en)	2000-07-05	Formulation for inhalation
AU2002221741A1 (en)	2002-07-18	Inhalative solution formulation containing a tiotropium salt
AU2173802A (en)	2002-05-15	Inhalative solution formulation containing a tiotropium salt
PL371204A1 (en)	2005-06-13	Aerosol formulation for inhalation comprising a tiotropium salt
AU2002221738A1 (en)	2002-07-18	Inhalative solution formulation containing a tiotropium salt
HUP0300808A3 (en)	2005-10-28	Fungicidal formulation containing triazolopyridine derivative
AP2003002783A0 (en)	2003-06-30	Medicament containing activted antihtrombin iii
EP1406592A4 (en)	2010-03-17	MEDICAL AEROSOL FORMULATION WITH PAIR SALT / ION
EP1429732A4 (en)	2005-01-26	CORE FORMULATION
GB0013400D0 (en)	2000-07-26	A formulation
GB0019132D0 (en)	2000-09-27	A solution monitor
GB0015079D0 (en)	2000-08-09	Solution for pharmaceutical use
TW459479U (en)	2001-10-11	Agent dispenser for aquarium
CA91072S (en)	2000-12-15	Salt platform
PL379448A1 (pl)	2006-09-18	Sposób wytwarzania preparatu zawierającego substancję aktywną w mikrodawce
GB0128138D0 (en)	2002-01-16	Pharmaceutical use