IL155693A0 - Cyclic peptide analogs of somatostatin - Google Patents

Cyclic peptide analogs of somatostatin

Info

Publication number: IL155693A0
Authority: IL; Israel
Prior art keywords: somatostatin; cyclic peptide; peptide analogs; terminus residue; disulfide bond
Prior art date: 1995-09-29

Application number

IL15569396A

Other languages

English (en)

Original Assignee

Sod Conseils Rech Applic

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-29

Filing date

1996-09-04

Publication date

2003-11-23

1996-09-04 Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic

2003-11-23 Publication of IL155693A0 publication Critical patent/IL155693A0/xx

Links

108010069514 Cyclic Peptides Proteins 0.000 title abstract 2
102000001189 Cyclic Peptides Human genes 0.000 title abstract 2
102000005157 Somatostatin Human genes 0.000 title abstract 2
108010056088 Somatostatin Proteins 0.000 title abstract 2
NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title abstract 2
229960000553 somatostatin Drugs 0.000 title abstract 2

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/16—Somatostatin; related peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Endocrinology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Zoology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IL15569396A 1995-09-29 1996-09-04 Cyclic peptide analogs of somatostatin IL155693A0 (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US463395P	1995-09-29	1995-09-29
US08/578,037 US5708135A (en)	1995-09-29	1995-12-26	Cyclic peptide analogs of somatostatin
PCT/US1996/014230 WO1997011962A1 (fr)	1995-09-29	1996-09-04	Analogues peptides cycliques de somatostatine
IL12335796A IL123357A0 (en)	1995-09-29	1996-09-04	Cyclic peptide analogs of somatostatin

Publications (1)

Publication Number	Publication Date
IL155693A0 true IL155693A0 (en)	2003-11-23

Family

ID=26673267

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL15569396A IL155693A0 (en)	1995-09-29	1996-09-04	Cyclic peptide analogs of somatostatin
IL12335796A IL123357A0 (en)	1995-09-29	1996-09-04	Cyclic peptide analogs of somatostatin

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL12335796A IL123357A0 (en)	1995-09-29	1996-09-04	Cyclic peptide analogs of somatostatin

Country Status (23)

Country	Link
US (2)	US5708135A (fr)
EP (1)	EP0859785B1 (fr)
JP (1)	JP3983806B2 (fr)
KR (1)	KR100430716B1 (fr)
CN (1)	CN1154657C (fr)
AT (1)	ATE201696T1 (fr)
AU (1)	AU711423B2 (fr)
BR (1)	BR9610725A (fr)
CA (1)	CA2229544C (fr)
CZ (1)	CZ289282B6 (fr)
DE (1)	DE69613137T2 (fr)
DK (1)	DK0859785T3 (fr)
ES (1)	ES2158340T3 (fr)
GR (1)	GR3036447T3 (fr)
HU (1)	HU221979B1 (fr)
IL (2)	IL155693A0 (fr)
NO (1)	NO318369B1 (fr)
NZ (1)	NZ316822A (fr)
PL (1)	PL325959A1 (fr)
PT (1)	PT859785E (fr)
SK (1)	SK29298A3 (fr)
TW (1)	TW514642B (fr)
WO (1)	WO1997011962A1 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7238340B1 (en) *	1991-11-27	2007-07-03	Cis Bio International	Monoamine, diamide, thiol-containing metal chelating agents
US5708135A (en) *	1995-09-29	1998-01-13	Biomeasure Incorporated	Cyclic peptide analogs of somatostatin
US6262229B1 (en)	1996-12-04	2001-07-17	Biomeasure Incorporated	Somatostatin antagonists
IL130166A0 (en) *	1996-12-04	2000-06-01	Sod Conseils Rech Applic	Somatostatin antagonists
US5972893A (en) *	1997-05-06	1999-10-26	Cedars-Sinai Medical Center	Method of treating hyperprolactinemia and prolactinomas
EP1332762A1 (fr) *	1997-05-01	2003-08-06	Cedars-Sinai Medical Center	Méthode de traitement de l' hyperprolactinémie et des prolactinomes
DK0979098T3 (da) *	1997-05-01	2003-07-14	Sod Conseils Rech Applic	Fremgangsmåde til behandling af hyperprolaktinæmi og prolaktinomer
EP0981364B1 (fr) *	1997-05-13	2006-03-01	Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S.	Procede et compositions pour traiter l'hyperlipidemie
CA2289499C (fr) *	1997-05-13	2010-02-23	Michael Anthony Cawthorne	Somatostatine et agonistes de somatostatine pour traiter l'insensibilite a l'insuline et le syndrome x
US6004928A (en) *	1997-05-13	1999-12-21	Biomeasure, Incorporated	Method of treating hyperlipidemia
CA2290592A1 (fr) *	1997-05-13	1998-11-19	Michael Anthony Cawthorne	Somatostatine et agonistes de somatostatine servant a la reduction du poids corporel
US6465613B1 (en)	1998-11-19	2002-10-15	Tulane University	Hydrophilic somatostatin analogs
US6903074B1 (en)	1999-06-04	2005-06-07	Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S.	Neuromedin b and somatostatin receptor agonists
US6864234B1 (en)	1999-06-25	2005-03-08	Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S.	Somatostatin agonists
US6358491B1 (en)	1999-08-27	2002-03-19	Berlex Laboratories, Inc.	Somatostatin analogs
US6579967B1 (en)	1999-12-14	2003-06-17	The Salk Institute For Biological Studies	Receptor-selective somatostatin analogs
US7019109B2 (en) *	2001-03-16	2006-03-28	The Salk Institute For Bilogical Studies	SSTR1-selective analogs
PL369336A1 (en)	2001-09-21	2005-04-18	The Administrators Of The Tulane Educational Fund	Diagnostic or therapeutic somatostatin or bombesin analog conjugates and uses thereof
BR0308090A (pt) *	2002-03-01	2006-04-11	Univ Tulane	conjugados de agentes citotóxicos ou terapêuticos e peptìdios biologicamente ativos
WO2004009614A2 (fr) *	2002-07-24	2004-01-29	The Salk Institute For Biological Studies	Analogues de la somastatine selectifs du recepteur (sstr4)
JP2006522100A (ja) *	2003-03-10	2006-09-28	バイオジェンアイデックインク	標的化ペプチドに対するチオール媒介性薬物結合
CN100475271C (zh)	2003-08-20	2009-04-08	加利福尼亚大学董事会	具有抑制生长激素释放活性的促生长素抑制素类似物
US8691761B2 (en)	2006-10-16	2014-04-08	Jean E. F. Rivier	Somatostatin receptor 2 antagonists
PL2383289T3 (pl)	2006-10-16	2015-03-31	Salk Inst Biological Studies	Antagoniści somatostatyny selektywni względem receptora (SSTR2)
CA2818833A1 (fr)	2010-11-29	2012-06-07	Thomas Urs Thueer	Module medicamenteux a engagement de reservoir automatique

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2416048A1 (de) *	1974-04-03	1975-10-30	Hoechst Ag	Neue peptide mit biologischer wirkung
US4133782A (en) *	1976-06-07	1979-01-09	The Salk Institute For Biological Studies	Somatostatin analogs with dissociated biological activities
US4211693A (en) *	1977-09-20	1980-07-08	The Salk Institute For Biological Studies	Peptides with para-substituted phenylalanine
US4225472A (en) *	1979-05-29	1980-09-30	American Home Products Corporation	Truncated somatostatin analogs
FR2523125A1 (fr) *	1982-03-08	1983-09-16	Sanofi Sa	Analogues de la somatostatine a activite biologique modifiee et medicaments en contenant
US4428942A (en) *	1982-05-17	1984-01-31	The Salk Institute For Biological Studies	Analogs of somatostatin
GB8318552D0 (en) *	1983-07-08	1983-08-10	Sandoz Ltd	Organic compounds
US4853371A (en) *	1986-06-17	1989-08-01	The Administrators Of The Tulane Educational Fund	Therapeutic somatostatin analogs
US4798821A (en) *	1987-03-02	1989-01-17	Merck & Co., Inc.	Antihypertensive therapy for diabetics
AU639371B2 (en) *	1987-07-10	1993-07-22	Novartis Ag	Method of treating breast cancer
ES2091907T3 (es) *	1989-12-08	1996-11-16	Univ Tulane	Analogos octapeptidos de somatostina con una threonina en la sexta posicion.
JPH03252783A (ja) *	1990-03-02	1991-11-12	Hitachi Ltd	データ処理装置
JPH04227540A (ja) *	1990-04-04	1992-08-17	Hitachi Ltd	演算処理装置及びディジタル信号処理プロセッサ
US5358934A (en) *	1992-12-11	1994-10-25	The United States Of America As Represented By The Secretary Of Agriculture	Materials and methods for control of pests
JP3904244B2 (ja) *	1993-09-17	2007-04-11	株式会社ルネサステクノロジ	シングル・チップ・データ処理装置
US5708135A (en) *	1995-09-29	1998-01-13	Biomeasure Incorporated	Cyclic peptide analogs of somatostatin
JP3767085B2 (ja) *	1996-09-04	2006-04-19	セイコーエプソン株式会社	情報処理回路及びマイクロコンピュータ

1995
- 1995-12-26 US US08/578,037 patent/US5708135A/en not_active Expired - Lifetime
1996
- 1996-09-04 NZ NZ316822A patent/NZ316822A/en unknown
- 1996-09-04 CA CA002229544A patent/CA2229544C/fr not_active Expired - Fee Related
- 1996-09-04 BR BR9610725A patent/BR9610725A/pt not_active IP Right Cessation
- 1996-09-04 EP EP96929913A patent/EP0859785B1/fr not_active Expired - Lifetime
- 1996-09-04 ES ES96929913T patent/ES2158340T3/es not_active Expired - Lifetime
- 1996-09-04 PL PL96325959A patent/PL325959A1/xx unknown
- 1996-09-04 CN CNB961971770A patent/CN1154657C/zh not_active Expired - Fee Related
- 1996-09-04 WO PCT/US1996/014230 patent/WO1997011962A1/fr not_active Ceased
- 1996-09-04 AT AT96929913T patent/ATE201696T1/de not_active IP Right Cessation
- 1996-09-04 IL IL15569396A patent/IL155693A0/xx unknown
- 1996-09-04 DE DE69613137T patent/DE69613137T2/de not_active Expired - Lifetime
- 1996-09-04 AU AU69145/96A patent/AU711423B2/en not_active Ceased
- 1996-09-04 HU HU9802372A patent/HU221979B1/hu not_active IP Right Cessation
- 1996-09-04 DK DK96929913T patent/DK0859785T3/da active
- 1996-09-04 SK SK292-98A patent/SK29298A3/sk unknown
- 1996-09-04 KR KR10-1998-0701664A patent/KR100430716B1/ko not_active Expired - Fee Related
- 1996-09-04 CZ CZ1998489A patent/CZ289282B6/cs not_active IP Right Cessation
- 1996-09-04 IL IL12335796A patent/IL123357A0/xx unknown
- 1996-09-04 JP JP51344497A patent/JP3983806B2/ja not_active Expired - Fee Related
- 1996-09-04 PT PT96929913T patent/PT859785E/pt unknown
- 1996-09-26 TW TW085112054A patent/TW514642B/zh not_active IP Right Cessation
1998
- 1998-01-13 US US09/006,348 patent/US6001801A/en not_active Expired - Fee Related
- 1998-03-27 NO NO19981395A patent/NO318369B1/no unknown
2001
- 2001-08-27 GR GR20010401297T patent/GR3036447T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR100430716B1 (ko)	2004-09-08
CZ289282B6 (cs)	2001-12-12
GR3036447T3 (en)	2001-11-30
EP0859785A4 (fr)	1999-05-26
HUP9802372A2 (hu)	1999-02-01
KR20000004896A (ko)	2000-01-25
AU711423B2 (en)	1999-10-14
TW514642B (en)	2002-12-21
DE69613137D1 (de)	2001-07-05
CZ48998A3 (cs)	1998-07-15
JP3983806B2 (ja)	2007-09-26
HU221979B1 (hu)	2003-03-28
BR9610725A (pt)	1999-07-13
ATE201696T1 (de)	2001-06-15
NO981395D0 (no)	1998-03-27
DK0859785T3 (da)	2001-08-27
HUP9802372A3 (en)	2000-03-28
US5708135A (en)	1998-01-13
CN1197460A (zh)	1998-10-28
AU6914596A (en)	1997-04-17
PT859785E (pt)	2001-11-30
EP0859785A1 (fr)	1998-08-26
PL325959A1 (en)	1998-08-17
WO1997011962A1 (fr)	1997-04-03
NO318369B1 (no)	2005-03-14
SK29298A3 (en)	1998-08-05
ES2158340T3 (es)	2001-09-01
NZ316822A (en)	1999-10-28
EP0859785B1 (fr)	2001-05-30
IL123357A0 (en)	1998-09-24
CA2229544C (fr)	2007-11-20
NO981395L (no)	1998-03-27
US6001801A (en)	1999-12-14
CA2229544A1 (fr)	1997-04-03
DE69613137T2 (de)	2001-11-15
CN1154657C (zh)	2004-06-23
JPH11512707A (ja)	1999-11-02

Publication	Publication Date	Title
IL123357A0 (en)	1998-09-24	Cyclic peptide analogs of somatostatin
PL312989A1 (en)	1996-05-27	Therapeutic derivatives of peptides
ES2169251T3 (es)	2002-07-01	Peptidos de somatostatina.
MY123740A (en)	2006-06-30	Il-13 receptor polypeptide
PT1144607E (pt)	2009-04-22	Novos métodos para apresentar (poli)peptídeos/ proteínas em partículas bacteriofágicas através de ligações dissulfureto
AU6368990A (en)	1991-04-11	Radiolabeled anticoagulant peptides
CA2195395A1 (fr)	1996-02-15	Analogues de la somatostatine hexapeptidique cyclique
FI961044A0 (fi)	1996-03-06	Kininogeeni-inhibiittorit
EP0644769A4 (fr)	1995-08-09	Peptides biologiquement actifs presentant des substitutions n-terminales.
IL130166A0 (en)	2000-06-01	Somatostatin antagonists
ES2190605T3 (es)	2003-08-01	Peptido con afinidad hacia el factor de coagulacion viii.
ZA899247B (en)	1990-09-26	Anticoagulant peptides
GB2267496A (en)	1993-12-08	Analogs of piscine LHRH
TW336938B (en)	1998-07-21	Calcium channel blocking polypeptides from filistata hibernalis
GR3021660T3 (en)	1997-02-28	Anticoagulant peptides
ZA967972B (en)	1997-05-27	Cyclic peptide analogs of somatostatin
GB9420293D0 (en)	1994-11-23	HIV cyclic peptide sulfides
NZ239930A (en)	1993-01-27	Peptides related to a hirudin fragment but comprising synthetic amino acids, pseudopeptide bonds or non cysteine cyclisation
MX9707904A (es)	1997-11-29	Analogos del factor de liberacion de la hormona del crecimiento.
PL55138Y1 (en)	1997-04-30	Resilent sealing ring
ZA973029B (en)	1997-10-13	Expression of recombinant peptides.
SI0835263T1 (en)	2002-06-30	Somatostatin peptides