IL156136A0 - Therapeutic combination of amlodipine and benazepril - Google Patents

Therapeutic combination of amlodipine and benazepril

Info

Publication number: IL156136A0
Authority: IL; Israel
Prior art keywords: amlodipine; pharmaceutically acceptable; benazepril; disease; corresponds
Prior art date: 2000-12-18

Application number

IL15613600A

Other languages

English (en)

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-18

Filing date

2000-12-18

Publication date

2003-12-23

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21742073&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL156136(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2000-12-18 Application filed by Novartis Ag filed Critical Novartis Ag

2003-12-23 Publication of IL156136A0 publication Critical patent/IL156136A0/xx

Links

HTIQEAQVCYTUBX-UHFFFAOYSA-N amlodipine Chemical compound CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1Cl HTIQEAQVCYTUBX-UHFFFAOYSA-N 0.000 title abstract 3
229960000528 amlodipine Drugs 0.000 title abstract 3
XPCFTKFZXHTYIP-PMACEKPBSA-N Benazepril Chemical compound C([C@@H](C(=O)OCC)N[C@@H]1C(N(CC(O)=O)C2=CC=CC=C2CC1)=O)CC1=CC=CC=C1 XPCFTKFZXHTYIP-PMACEKPBSA-N 0.000 title abstract 2
229960004530 benazepril Drugs 0.000 title abstract 2
230000001225 therapeutic effect Effects 0.000 title 1
150000003839 salts Chemical class 0.000 abstract 3
239000005541 ACE inhibitor Substances 0.000 abstract 1
206010002383 Angina Pectoris Diseases 0.000 abstract 1
206010007559 Cardiac failure congestive Diseases 0.000 abstract 1
208000007342 Diabetic Nephropathies Diseases 0.000 abstract 1
206010019233 Headaches Diseases 0.000 abstract 1
206010019280 Heart failures Diseases 0.000 abstract 1
206010020772 Hypertension Diseases 0.000 abstract 1
208000007177 Left Ventricular Hypertrophy Diseases 0.000 abstract 1
208000019693 Lung disease Diseases 0.000 abstract 1
208000021642 Muscular disease Diseases 0.000 abstract 1
201000009623 Myopathy Diseases 0.000 abstract 1
208000018262 Peripheral vascular disease Diseases 0.000 abstract 1
208000001647 Renal Insufficiency Diseases 0.000 abstract 1
208000006011 Stroke Diseases 0.000 abstract 1
229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 abstract 1
229960003619 benazepril hydrochloride Drugs 0.000 abstract 1
VPSRQEHTHIMDQM-FKLPMGAJSA-N benazepril hydrochloride Chemical compound Cl.C([C@@H](C(=O)OCC)N[C@@H]1C(N(CC(O)=O)C2=CC=CC=C2CC1)=O)CC1=CC=CC=C1 VPSRQEHTHIMDQM-FKLPMGAJSA-N 0.000 abstract 1
229960004067 benazeprilat Drugs 0.000 abstract 1
MADRIHWFJGRSBP-ROUUACIJSA-N benazeprilat Chemical compound C([C@H](N[C@H]1CCC2=CC=CC=C2N(C1=O)CC(=O)O)C(O)=O)CC1=CC=CC=C1 MADRIHWFJGRSBP-ROUUACIJSA-N 0.000 abstract 1
230000036772 blood pressure Effects 0.000 abstract 1
230000000747 cardiac effect Effects 0.000 abstract 1
208000010877 cognitive disease Diseases 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
208000033679 diabetic kidney disease Diseases 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000012458 free base Substances 0.000 abstract 1
231100000869 headache Toxicity 0.000 abstract 1
201000006370 kidney failure Diseases 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
208000010125 myocardial infarction Diseases 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
208000002815 pulmonary hypertension Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Hematology (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Pulmonology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IL15613600A 2000-12-18 2000-12-18 Therapeutic combination of amlodipine and benazepril IL156136A0 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US2000/034246 WO2002049645A1 (en)	2000-12-18	2000-12-18	Therapeutic combination of amlodipine and benazepril

Publications (1)

Publication Number	Publication Date
IL156136A0 true IL156136A0 (en)	2003-12-23

Family

ID=21742073

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
IL15613600A IL156136A0 (en)	2000-12-18	2000-12-18	Therapeutic combination of amlodipine and benazepril
IL15626701A IL156267A0 (en)	2000-12-18	2001-12-17	Therapeutic combination of amlodipine and benazepril/benazeprilat
IL190801A IL190801A0 (en)	2000-12-18	2008-04-10	Therapeutic combination of amlodipine and benazepril/benazeprilat
IL190802A IL190802A0 (en)	2000-12-18	2008-04-10	Therapeutic combination of amlodipine and benazepril/benazeprilat

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
IL15626701A IL156267A0 (en)	2000-12-18	2001-12-17	Therapeutic combination of amlodipine and benazepril/benazeprilat
IL190801A IL190801A0 (en)	2000-12-18	2008-04-10	Therapeutic combination of amlodipine and benazepril/benazeprilat
IL190802A IL190802A0 (en)	2000-12-18	2008-04-10	Therapeutic combination of amlodipine and benazepril/benazeprilat

Country Status (26)

Country	Link
EP (3)	EP1365761A1 (de)
JP (3)	JP2004516266A (de)
KR (3)	KR20040007420A (de)
CN (2)	CN1461218A (de)
AT (1)	ATE338549T1 (de)
AU (4)	AU2581601A (de)
BR (2)	BR0017386A (de)
CA (2)	CA2432638A1 (de)
CY (1)	CY1106275T1 (de)
CZ (2)	CZ20031678A3 (de)
DE (1)	DE60122928T2 (de)
DK (1)	DK1345607T3 (de)
EC (1)	ECSP034658A (de)
ES (1)	ES2272565T3 (de)
HU (2)	HUP0302455A3 (de)
IL (4)	IL156136A0 (de)
MX (2)	MXPA03005462A (de)
NO (2)	NO20032765L (de)
NZ (1)	NZ526467A (de)
PL (2)	PL362252A1 (de)
PT (1)	PT1345607E (de)
RU (1)	RU2292206C2 (de)
SI (1)	SI1345607T1 (de)
SK (2)	SK7652003A3 (de)
WO (2)	WO2002049645A1 (de)
ZA (1)	ZA200304514B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL370270A1 (en) *	2001-11-23	2005-05-16	Solvay Pharmaceuticals Gmbh	Hypertonia treatment during the acute phase of a cerebrovascular accident
US20040229901A1 (en) *	2003-02-24	2004-11-18	Lauren Otsuki	Method of treatment of disease using an adenosine A1 receptor antagonist
AU2004233852A1 (en)	2003-04-25	2004-11-11	Novacardia, Inc.	Method of improved diuresis in individuals with impaired renal function
CA2542757A1 (en) *	2003-10-20	2005-04-28	Novartis Ag	Use of organic compounds
WO2005074927A1 (en) *	2004-02-09	2005-08-18	Novartis Ag	Therapeutic combination of amlodipine and benazepril/ benazeprilat for the treatment of hypertension
WO2005079772A2 (en) *	2004-02-18	2005-09-01	Sepracor Inc.	Combination of (s)-amlodipine and an ace inhibitor, and methods for reducing hypertension
DE102004011512B4 (de)	2004-03-08	2022-01-13	Boehringer Ingelheim Vetmedica Gmbh	Pharmazeutische Zubereitung enthaltend Pimobendan
US8980894B2 (en)	2004-03-25	2015-03-17	Boehringer Ingelheim Vetmedica Gmbh	Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
EP1579862A1 (de)	2004-03-25	2005-09-28	Boehringer Ingelheim Vetmedica Gmbh	Verwendung von PDE III Ihibitoren zur Reduktion der Herzgrösse in an Herzversagen leidenden Säugern
US20080268049A1 (en) *	2005-02-11	2008-10-30	Dhaliwal Mona	Stable Solid Dosage Forms of Amlodipine and Benazepril
WO2006092732A2 (en) *	2005-03-04	2006-09-08	Aurobindo Pharma Ltd	Stable solid dosage form of antihypertensive agent
EP1863457A2 (de)	2005-03-15	2007-12-12	Lupin Ltd.	Pharmazeutische zusammensetzungen von amlodipin und benazepril
JP2009508948A (ja) *	2005-09-28	2009-03-05	テバファーマシューティカルインダストリーズリミティド	アムロジピンベシレート及びベナゼプリル塩酸塩の安定した組合わせ
DK1797885T3 (da) *	2005-09-28	2008-07-14	Teva Pharma	Stabil kombination af amlodipinbesylat og benazeprilhydrochlorid
US8158146B2 (en)	2005-09-28	2012-04-17	Teva Pharmaceutical Industries Ltd.	Stable combinations of amlodipine besylate and benazepril hydrochloride
EP1920785A1 (de)	2006-11-07	2008-05-14	Boehringer Ingelheim Vetmedica Gmbh	Pimobendan-Cyclodextrin Komplex enthaltendes flüssiges Präparat
IT1398168B1 (it) *	2010-02-16	2013-02-14	Chiesi Farma Spa	Uso di ingredienti attivi in combinazione per il trattamento delle complicanze del diabete.
EP2585051B2 (de)	2010-06-23	2020-04-08	KRKA, tovarna zdravil, d.d., Novo mesto	Pharmazeutische orale dosierformen mit lercandipin und enalapril und ihren pharmazeutisch akzeptablen salzen
CN102389431A (zh) *	2011-09-28	2012-03-28	济南龙华医药技术有限公司	一种含有盐酸贝尼地平和盐酸贝那普利的复方制剂及其应用
SI2793866T1 (sl) *	2011-12-21	2016-01-29	Novartis Tiergesundheit Ag	Nova kombinacija
EP3167876B1 (de)	2012-03-15	2021-09-08	Boehringer Ingelheim Vetmedica GmbH	Pharmazeutische tablettenformulierung für den veterinärmedizinischen sektor, verfahren zur herstellung und verwendung davon
WO2014035707A1 (en) *	2012-08-25	2014-03-06	The Johns Hopkins University	Gapdh cascade inhibitor compounds and methods of use and treatment of stress induced disorders including mental illness
DK3021832T3 (da)	2013-07-19	2021-05-25	Boehringer Ingelheim Vetmedica Gmbh	Konserverede etherificerede cyclodextrinderivater indeholdende flydende vandig farmaceutisk sammensætning
ES2593210T3 (es)	2013-12-04	2016-12-07	Boehringer Ingelheim Vetmedica Gmbh	Composiciones farmacéuticas mejoradas de pimobendán
EP3434284A4 (de) *	2016-03-24	2019-11-13	Daiichi Sankyo Company, Limited	Medizin zur behandlung von nierenerkrankung
US10537570B2 (en)	2016-04-06	2020-01-21	Boehringer Ingelheim Vetmedica Gmbh	Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease
PE20191239A1 (es)	2016-11-16	2019-09-16	Abide Therapeutics Inc	Formas cristalinas de un inhibidor de magl
AU2017361254B2 (en)	2016-11-16	2021-09-23	H. Lundbeck A/S.	Pharmaceutical formulations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6162802A (en) *	1992-03-10	2000-12-19	Papa; Joseph	Synergistic combination therapy using benazepril and amlodipine for the treatment of cardiovascular disorders and compositions therefor
ATE235251T1 (de) *	1995-03-16	2003-04-15	Pfizer	Verwendung von amlodipin, eines seiner salze oder felodipin in kombination mit einem ace-hemmer zur herstellung eines arzneimittels zur behandlung von nicht ischämischer kongestiver herzinsuffizienz
WO1996031234A1 (en) *	1995-04-07	1996-10-10	Novartis Ag	Combination compositions containing benazepril or benazeprilat and valsartan
EP0795327A1 (de) *	1996-03-13	1997-09-17	Pfizer Inc.	Verwendung von Amlodipin zur Behandlung von Prophylaxe von kongestivem Herzversagen nichtischämischen Ursprungs

2000
- 2000-12-18 MX MXPA03005462A patent/MXPA03005462A/es not_active Application Discontinuation
- 2000-12-18 PL PL00362252A patent/PL362252A1/xx not_active Application Discontinuation
- 2000-12-18 AU AU2581601A patent/AU2581601A/xx active Pending
- 2000-12-18 CN CN00820080A patent/CN1461218A/zh active Pending
- 2000-12-18 CA CA002432638A patent/CA2432638A1/en not_active Abandoned
- 2000-12-18 BR BR0017386-0A patent/BR0017386A/pt not_active Application Discontinuation
- 2000-12-18 KR KR10-2003-7007578A patent/KR20040007420A/ko not_active Withdrawn
- 2000-12-18 SK SK765-2003A patent/SK7652003A3/sk not_active Application Discontinuation
- 2000-12-18 IL IL15613600A patent/IL156136A0/xx unknown
- 2000-12-18 HU HU0302455A patent/HUP0302455A3/hu unknown
- 2000-12-18 WO PCT/US2000/034246 patent/WO2002049645A1/en not_active Ceased
- 2000-12-18 EP EP00989288A patent/EP1365761A1/de not_active Withdrawn
- 2000-12-18 JP JP2002550985A patent/JP2004516266A/ja active Pending
- 2000-12-18 CZ CZ20031678A patent/CZ20031678A3/cs unknown
- 2000-12-18 AU AU2001225816A patent/AU2001225816B2/en not_active Ceased
2001
- 2001-12-17 JP JP2002550986A patent/JP2004519440A/ja not_active Withdrawn
- 2001-12-17 AU AU2002232620A patent/AU2002232620B9/en not_active Ceased
- 2001-12-17 EP EP01992150A patent/EP1345607B1/de not_active Revoked
- 2001-12-17 DK DK01992150T patent/DK1345607T3/da active
- 2001-12-17 CZ CZ20031677A patent/CZ301424B6/cs not_active IP Right Cessation
- 2001-12-17 KR KR10-2003-7007754A patent/KR20030061840A/ko not_active Ceased
- 2001-12-17 EP EP06003150A patent/EP1674099A1/de not_active Withdrawn
- 2001-12-17 SK SK764-2003A patent/SK7642003A3/sk not_active Application Discontinuation
- 2001-12-17 PL PL01360989A patent/PL360989A1/xx not_active Application Discontinuation
- 2001-12-17 CA CA002432282A patent/CA2432282A1/en not_active Abandoned
- 2001-12-17 RU RU2003121019/15A patent/RU2292206C2/ru not_active IP Right Cessation
- 2001-12-17 DE DE60122928T patent/DE60122928T2/de not_active Revoked
- 2001-12-17 AT AT01992150T patent/ATE338549T1/de active
- 2001-12-17 CN CNA018208398A patent/CN1481241A/zh active Pending
- 2001-12-17 BR BR0116228-4A patent/BR0116228A/pt not_active IP Right Cessation
- 2001-12-17 ES ES01992150T patent/ES2272565T3/es not_active Expired - Lifetime
- 2001-12-17 MX MXPA03005463A patent/MXPA03005463A/es active IP Right Grant
- 2001-12-17 KR KR1020097004242A patent/KR20090033914A/ko not_active Ceased
- 2001-12-17 SI SI200130662T patent/SI1345607T1/sl unknown
- 2001-12-17 HU HU0302456A patent/HUP0302456A3/hu unknown
- 2001-12-17 PT PT01992150T patent/PT1345607E/pt unknown
- 2001-12-17 AU AU3262002A patent/AU3262002A/xx active Pending
- 2001-12-17 IL IL15626701A patent/IL156267A0/xx unknown
- 2001-12-17 WO PCT/US2001/048808 patent/WO2002049646A1/en not_active Ceased
- 2001-12-17 NZ NZ526467A patent/NZ526467A/en unknown
2003
- 2003-06-10 ZA ZA200304514A patent/ZA200304514B/xx unknown
- 2003-06-17 EC EC2003004658A patent/ECSP034658A/es unknown
- 2003-06-17 NO NO20032765A patent/NO20032765L/no not_active Application Discontinuation
- 2003-06-17 NO NO20032766A patent/NO20032766L/no not_active Application Discontinuation
2006
- 2006-11-30 CY CY20061101728T patent/CY1106275T1/el unknown
2008
- 2008-04-10 IL IL190801A patent/IL190801A0/en unknown
- 2008-04-10 IL IL190802A patent/IL190802A0/en unknown
2009
- 2009-10-09 JP JP2009235225A patent/JP2010043111A/ja active Pending

Also Published As

Publication number	Publication date
AU2001225816B2 (en)	2005-10-13
BR0017386A (pt)	2004-01-13
CY1106275T1 (el)	2011-10-12
EP1674099A1 (de)	2006-06-28
ES2272565T3 (es)	2007-05-01
JP2004519440A (ja)	2004-07-02
AU3262002A (en)	2002-07-01
DE60122928T2 (de)	2007-09-06
ZA200304514B (en)	2004-05-10
ECSP034658A (es)	2003-07-25
IL190802A0 (en)	2008-11-03
EP1345607B1 (de)	2006-09-06
CZ20031678A3 (cs)	2003-10-15
PL360989A1 (en)	2004-09-20
KR20040007420A (ko)	2004-01-24
DE60122928D1 (de)	2006-10-19
SK7642003A3 (en)	2003-11-04
NO20032766D0 (no)	2003-06-17
NO20032766L (no)	2003-08-14
KR20090033914A (ko)	2009-04-06
IL156267A0 (en)	2004-01-04
WO2002049645A1 (en)	2002-06-27
HUP0302455A3 (en)	2005-05-30
AU2002232620B9 (en)	2005-11-24
HUP0302456A3 (en)	2004-05-28
ATE338549T1 (de)	2006-09-15
CN1481241A (zh)	2004-03-10
BR0116228A (pt)	2003-12-30
MXPA03005463A (es)	2003-09-25
PL362252A1 (en)	2004-10-18
EP1345607A1 (de)	2003-09-24
HUP0302456A2 (hu)	2003-11-28
AU2002232620B2 (en)	2005-11-03
NO20032765L (no)	2003-08-14
SI1345607T1 (sl)	2007-02-28
IL190801A0 (en)	2008-11-03
HUP0302455A2 (hu)	2003-11-28
NZ526467A (en)	2005-04-29
HK1059566A1 (en)	2004-07-09
CN1461218A (zh)	2003-12-10
NO20032765D0 (no)	2003-06-17
WO2002049646A1 (en)	2002-06-27
CA2432282A1 (en)	2002-06-27
EP1365761A1 (de)	2003-12-03
RU2292206C2 (ru)	2007-01-27
DK1345607T3 (da)	2006-12-27
CA2432638A1 (en)	2002-06-27
PT1345607E (pt)	2007-01-31
RU2003121019A (ru)	2005-01-20
JP2004516266A (ja)	2004-06-03
KR20030061840A (ko)	2003-07-22
CZ20031677A3 (cs)	2003-10-15
CZ301424B6 (cs)	2010-02-24
MXPA03005462A (es)	2003-09-25
AU2581601A (en)	2002-07-01
JP2010043111A (ja)	2010-02-25
SK7652003A3 (en)	2003-12-02

Publication	Publication Date	Title
IL190801A0 (en)	2008-11-03	Therapeutic combination of amlodipine and benazepril/benazeprilat
RU2243768C2 (ru)	2005-01-10	Гипотензивная комбинация валсартана и блокатора кальциевых каналов
WO2003041725A3 (de)	2004-03-18	REGULATION DER cGMP-SPEZIFISCHEN PHOSPHODIESTERASE 9A
KR101389879B1 (ko)	2014-04-29	심부전의 치료에서의 동결절 Ｉｆ 전류 억제제 및 안지오텐신-전환 효소 억제제의 회합물의 용도
KR20090047424A (ko)	2009-05-12	굴심방 결절 Ｉｆ 전류 억제제와 앤지오텐신 전환 효소 억제제의 회합체, 및 이를 함유한 약제 조성물
CA2214143A1 (en)	1996-10-10	Combination compositions containing benazepril or benazeprilat and valsartan
JP2003522768A5 (de)	2011-09-08
SG153644A1 (en)	2009-07-29	Therapeutic combination of amlodipine and benazepril
KR20070066922A (ko)	2007-06-27	굴심방 결절 Ｉｆ 전류 억제제 및 칼슘 억제제의 회합체 및이를 함유하는 약제 조성물
RU2005119970A (ru)	2006-01-20	Оптически активное производное дигидропиридина
RU2003121016A (ru)	2005-02-27	Терапевтическая комбинация амлодипина и беназеприла
DK0554107T3 (da)	1999-12-06	Substituerede triazoler som angiotensin II inhibitorer
HK1106442B (en)	2011-11-18	Association of a sinus node if, current inhibitor and a calcium inhibitor, and pharmaceutical compositions containing it
HK1106444B (en)	2011-04-21	New association of a sinus node if current inhibitor and an angiotensin-converting enzyme inhibitor, and pharmaceutical compositions containing it