IL157340A0 - Novel succinate salt of o-desmethyl-venlafaxine - Google Patents

Novel succinate salt of o-desmethyl-venlafaxine

Info

Publication number: IL157340A0
Authority: IL; Israel
Prior art keywords: desmethyl; venlafaxine; succinate salt; novel succinate; novel
Prior art date: 2001-02-12

Application number

IL15734002A

Other languages

English (en)

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-12

Filing date

2002-02-11

Publication date

2004-02-19

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26952945&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL157340(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-02-11 Application filed by Wyeth Corp filed Critical Wyeth Corp

2004-02-19 Publication of IL157340A0 publication Critical patent/IL157340A0/xx

Links

KYYIDSXMWOZKMP-UHFFFAOYSA-N O-desmethylvenlafaxine Chemical compound C1CCCCC1(O)C(CN(C)C)C1=CC=C(O)C=C1 KYYIDSXMWOZKMP-UHFFFAOYSA-N 0.000 title 1
150000003890 succinate salts Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/02—Dicarboxylic acids
- C07C55/10—Succinic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Emergency Medicine (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Physical Education & Sports Medicine (AREA)
Gynecology & Obstetrics (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Obesity (AREA)
Hematology (AREA)
Child & Adolescent Psychology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL15734002A 2001-02-12 2002-02-11 Novel succinate salt of o-desmethyl-venlafaxine IL157340A0 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US26821401P	2001-02-12	2001-02-12
US29796301P	2001-06-13	2001-06-13
PCT/US2002/004103 WO2002064543A2 (en)	2001-02-12	2002-02-11	Novel succinate salt of o-desmethyl-venlafaxine

Publications (1)

Publication Number	Publication Date
IL157340A0 true IL157340A0 (en)	2004-02-19

Family

ID=26952945

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
IL15734002A IL157340A0 (en)	2001-02-12	2002-02-11	Novel succinate salt of o-desmethyl-venlafaxine
IL157340A IL157340A (en)	2001-02-12	2003-08-11	O salts - Desmethyl - and nalfaxine succinate and the pharmaceutical compositions containing them
IL200255A IL200255A (en)	2001-02-12	2009-08-05	Method of preparing o-desmethyl-venlafaxine
IL209444A IL209444A (en)	2001-02-12	2010-11-18	Uses of O-Desmethyl-Venelfaxine Crystalline Succin

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
IL157340A IL157340A (en)	2001-02-12	2003-08-11	O salts - Desmethyl - and nalfaxine succinate and the pharmaceutical compositions containing them
IL200255A IL200255A (en)	2001-02-12	2009-08-05	Method of preparing o-desmethyl-venlafaxine
IL209444A IL209444A (en)	2001-02-12	2010-11-18	Uses of O-Desmethyl-Venelfaxine Crystalline Succin

Country Status (30)

Country	Link
US (5)	US6673838B2 (de)
EP (3)	EP2319826A1 (de)
JP (1)	JP4220243B2 (de)
KR (1)	KR100875610B1 (de)
CN (2)	CN101671260A (de)
AR (2)	AR032671A1 (de)
AT (1)	ATE369330T1 (de)
AU (1)	AU2002250058B2 (de)
BR (1)	BR0207157A (de)
CA (2)	CA2666611A1 (de)
CY (1)	CY1106952T1 (de)
DE (1)	DE60221642T3 (de)
DK (1)	DK1360169T3 (de)
EA (1)	EA011451B1 (de)
ES (1)	ES2290281T5 (de)
HN (1)	HN2002000030A (de)
HU (1)	HUP0303128A3 (de)
IL (4)	IL157340A0 (de)
MX (1)	MXPA03007043A (de)
NO (1)	NO328807B1 (de)
NZ (1)	NZ539791A (de)
PA (1)	PA8539901A1 (de)
PE (1)	PE20020877A1 (de)
PL (2)	PL211788B1 (de)
PT (1)	PT1360169E (de)
SI (1)	SI1360169T1 (de)
TW (1)	TWI318201B (de)
UY (1)	UY27175A1 (de)
WO (1)	WO2002064543A2 (de)
ZA (1)	ZA200307116B (de)

Families Citing this family (115)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2348021A1 (en)	1998-10-30	2000-05-11	Ajinomoto Co., Inc.	Crystallization processes for the formation of stable crystals of aspartame derivative
US6342533B1 (en)	1998-12-01	2002-01-29	Sepracor, Inc.	Derivatives of (−)-venlafaxine and methods of preparing and using the same
HUP0200898A3 (en) *	1999-04-06	2005-09-28	Sepracor Inc	Derivatives of venlafaxine and methods of preparing and using the same
EP2319826A1 (de) *	2001-02-12	2011-05-11	Wyeth LLC	O-Desmethyl-Venlafaxine Succinat Salz
US20050244498A1 (en) *	2001-09-14	2005-11-03	Biovail Laboratories, Inc.	Modified-release compositions of at least one form of venlafaxine
UA80543C2 (en)	2001-12-04	2007-10-10	Wyeth Corp	Method for the preparation of o-desmethylvenlafaxine
AU2003219117A1 (en) *	2002-03-28	2003-10-13	Synthon B.V.	Extended release venlafaxine formulations
AU2003247515A1 (en) *	2002-06-10	2003-12-22	Wyeth	Novel formate salt of o-desmethyl-venlafaxine
JP2006500427A (ja) *	2002-08-29	2006-01-05	アラクノーバ・セラピューティックス・リミテッド	（４−（２−フルオロフェニル）−６−メチル−２−（１−ピペラジニル）チエノ［２，３−ｄ］ピリミジンの新規治療的使用
US7345096B2 (en) *	2002-10-15	2008-03-18	Wyeth	Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms
PL1628685T3 (pl)	2003-04-25	2011-05-31	Gilead Sciences Inc	Przeciwwirusowe analogi fosfonianowe
JP2004359665A (ja) *	2003-05-30	2004-12-24	Rohm & Haas Co	生体利用性増強剤を含有する治療組成物
US7550485B2 (en)	2003-10-14	2009-06-23	Wyeth	Substituted N-heterocycle derivatives and methods of their use
US7365076B2 (en)	2003-10-14	2008-04-29	Wyeth	Substituted aryl cycloalkanol derivatives and methods of their use
US7419980B2 (en)	2003-10-14	2008-09-02	Wyeth	Fused-aryl and heteroaryl derivatives and methods of their use
US7491723B2 (en)	2003-10-14	2009-02-17	Wyeth	Alkanol and cycloalkanol-amine derivatives and methods of their use
US7531543B2 (en)	2003-10-14	2009-05-12	Wyeth	Phenylpiperazine cycloalkanol derivatives and methods of their use
US7524846B2 (en)	2003-10-14	2009-04-28	Wyeth	Arylalkyl- and cycloalkylalkyl-piperazine derivatives and methods of their use
US7402698B2 (en)	2003-10-14	2008-07-22	Wyeth	Secondary amino-and cycloamino-cycloalkanol derivatives and methods of their use
CN1917860A (zh)	2004-02-06	2007-02-21	惠氏公司	多颗粒o－去甲基文拉法辛盐及其用途
US7414052B2 (en)	2004-03-30	2008-08-19	Wyeth	Phenylaminopropanol derivatives and methods of their use
US7517899B2 (en)	2004-03-30	2009-04-14	Wyeth	Phenylaminopropanol derivatives and methods of their use
US7439280B2 (en) *	2004-04-06	2008-10-21	Basf Corporation	Lignocellulosic composite material and method for preparing the same
EP1773321A2 (de) *	2004-07-22	2007-04-18	Wyeth	Verfahren zur behandlung von erkrankungen und zuständen des nervensystems
MX2007000851A (es) *	2004-07-22	2007-03-26	Wyeth Corp	Procedimiento para el tratamiento de trastornos y dolencias del sistema nervioso.
CN101410106A (zh) *	2004-07-22	2009-04-15	惠氏公司	治疗神经系统障碍和病症的方法
EP1778251B1 (de)	2004-07-27	2011-04-13	Gilead Sciences, Inc.	Nukleosid phosphonat konjugate als anti hiv mittel
US20060193912A1 (en) *	2005-02-28	2006-08-31	Penwest Pharmaceuticals Co.	Controlled release O-desmethylvenlafaxine formulations
MX2007012167A (es) *	2005-03-31	2007-11-22	Wyeth Corp	Producto de combinacion de o-desmetilvenlafaxina y bazedoxifeno, y usos del mismo.
CN1955159B (zh) *	2005-06-17	2010-11-24	山东绿叶制药有限公司	用于阻断5-羟色胺以及去甲基肾上腺素再摄取的化合物,其制备方法及其用途
AU2006265008A1 (en) *	2005-07-06	2007-01-11	Sepracor Inc.	Combinations of eszopiclone and O-desmethylvenlafaxine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
PE20070247A1 (es) *	2005-07-15	2007-04-11	Wyeth Corp	Derivados dimetilamino como agentes inhibidores de la recaptacion doble de serotonina y norepinefrina con alta selectividad
US7687520B2 (en)	2005-07-15	2010-03-30	Wyeth Llc	Serotonin and norepinephrine reuptake inhibitors and uses thereof
US7595340B2 (en)	2005-07-15	2009-09-29	Wyeth	Serotonin and norepinephrine reuptake inhibitor and uses thereof
WO2007013936A2 (en) *	2005-07-21	2007-02-01	Wyeth	Method for treating nervous system disorders and conditions
GT200600397A (es) *	2005-09-07	2007-08-28		Formulas topicas conteniendo o-desmetil venlafaxina (odv) o sus sales
GT200600396A (es) *	2005-09-07	2007-04-23		Dispositivos para la aplicacion de medicamentos transdermicos conteniendo o-desmetil venlafaxina (odv) o sus sales
CN1332946C (zh) *	2005-10-21	2007-08-22	中国人民解放军军事医学科学院放射与辐射医学研究所	作用于中枢神经系统的前药
PT1954669E (pt) *	2005-12-01	2015-10-23	Auspex Pharmaceuticals Inc	Feniletilaminas substituídas com actividade serotoninérgica e/ou norepinefrinérgica
JP2009518407A (ja) *	2005-12-05	2009-05-07	ワイス	置換１−（２−アミノ−１−フェニル−エチル）−シクロヘキサノールのエナンチオマーを選択的に合成するための方法
EP1973866A1 (de)	2005-12-20	2008-10-01	Synthon B.V.	Verfahren zur herstellung von desvenlafaxin
EP2007708A1 (de)	2006-04-17	2008-12-31	Teva Pharmaceutical Industries Ltd	Substanziell reines o-desmethylvenlafaxin und herstellungsverfahren dafür
MX2007016179A (es)	2006-04-17	2008-03-11	Teva Pharma	Formas cristalinas de o-desmetilvenlafaxina.
KR101424832B1 (ko) *	2006-05-16	2014-08-06	길리애드 사이언시즈, 인코포레이티드	악성 혈액 종양 치료 방법 및 악성 혈액 종양 치료용 조성물
US20090137846A1 (en) *	2006-07-26	2009-05-28	Valerie Niddam-Hildesheim	Processes for the synthesis of O-Desmethylvenlafaxine
US20080221356A1 (en) *	2006-07-26	2008-09-11	Valerie Niddam-Hildesheim	Processes for the synthesis of O-desmethylvenlafaxine
WO2008013993A2 (en) *	2006-07-26	2008-01-31	Teva Pharmaceutical Industries Ltd.	Processes for the synthesis of o-desmethylvenlafaxine
KR101019455B1 (ko)	2006-07-26	2011-03-07	테바 파마슈티컬 인더스트리즈 리미티드	Ｏ-데스메틸벤라팍신의 합성 방법
US20090069601A1 (en) *	2006-07-26	2009-03-12	Valerie Niddam-Hildesheim	Processes for the synthesis of O-desmethylvenlafaxine
US20100121108A1 (en) *	2006-08-04	2010-05-13	Medichem, S.A.	Process for synthesizing desvenlafaxine free base and salts or solvates thereof
CA2659295A1 (en) *	2006-08-08	2008-02-14	Generics [Uk] Limited	Novel hydrate form of o-desmethyl venlafaxine succinate
AU2007311625A1 (en) *	2006-10-18	2008-04-24	Generics [Uk] Limited	Polymorphs of O-desmethyl venlafaxine succinate
RU2009112105A (ru) *	2006-10-25	2010-11-27	Вайет (Us)	Выделенные гидрокси- и n-оксидные метаболиты и производные о-дезметилвенлафаксина и способы лечения
PT2125786E (pt) *	2006-12-21	2011-04-21	Pfizer Prod Inc	Sal succinato de 2-((4-(1-metil-4-(piridin-4-il)-1hpirazol- 3-il)fenoxi)metil)quinolina
WO2009027766A2 (en) *	2006-12-22	2009-03-05	Medichem, S.A.	New crystalline solid forms of o-desvenlafaxine base
US7820716B2 (en) *	2007-01-08	2010-10-26	Mai De Ltd	Crystalline polymorphs of desvenlafaxine succinate and their preparations
AR064987A1 (es) *	2007-01-22	2009-05-06	Medichem Sa	Proceso mejorado para sintetizar desvenlafaxina como base libre y sales o solvatos de la misma
WO2008093142A1 (en) *	2007-01-31	2008-08-07	Generics [Uk] Limited	Process for the preparation of o-desmethyl venlafaxine
KR101528326B1 (ko) *	2007-02-21	2015-06-11	선오비온 파마슈티컬스 인코포레이티드	（―）ｏ―데스메틸벤라팍신을 포함하는 고체 형태들 및 그들의 용도
WO2008110338A1 (en) *	2007-03-09	2008-09-18	Synthon B.V.	Polymorph of desvenlafaxine succinate
EP2049465A2 (de) *	2007-03-14	2009-04-22	Teva Pharmaceutical Industries Ltd.	Verfahren zur herstellung von o-desmethylvenlafaxin in festem zustand
ES2693948T3 (es)	2007-03-15	2018-12-14	Auspex Pharmaceuticals, Inc.	Fenetilamina sustituida con actividad serotoninérgica y/o norepinefrinérgica
WO2008156748A2 (en) *	2007-06-15	2008-12-24	Teva Pharmaceutical Industries Ltd.	Crystal forms of o-desmethylvenlafaxine succinate
US20100210719A1 (en) *	2007-07-12	2010-08-19	Dr. Reddy's Laboratories Ltd.	O-desmethylvenlafaxine
IN2007CH01519A (de) *	2007-07-16	2009-09-11	Matrix Lab Ltd
WO2009017813A1 (en) *	2007-08-02	2009-02-05	Teva Pharmaceutical Industries Ltd.	O-desmethyl venlafaxine saccharinate
US20090076162A1 (en) *	2007-09-17	2009-03-19	Protia, Llc	Deuterium-enriched desvenlafaxine
US20100330172A1 (en) *	2007-10-16	2010-12-30	Alphapharm Pty Ltd	Controlled-release pharmaceutical formulation
US20110046231A1 (en) *	2007-10-22	2011-02-24	Actavis Group Ptc Ehf	Solid forms of (±)-o-desmethylvenlafaxine salts
AU2008315740A1 (en)	2007-10-26	2009-04-30	Generics [Uk] Limited	Process for preparing O-desmethylvenlafaxine
KR101343027B1 (ko) *	2007-11-26	2013-12-18	테바 파마슈티컬 인더스트리즈 리미티드	Ｏ-데스메틸벤라팍신 푸마레이트의 결정형
EP2085377A1 (de)	2008-01-29	2009-08-05	LEK Pharmaceuticals D.D.	Neuartige Salze von O-Desmethyl-Venlafaxin
EP2262758A4 (de) *	2008-03-12	2011-12-07	Reddys Lab Ltd Dr	O-desmethylvenlafaxin-salze
WO2009118758A2 (en) *	2008-03-24	2009-10-01	Sun Pharmaceutical Industries Ltd.	Novel crystalline forms of desvenlafaxine succinate
IN2008CH00818A (de) *	2008-04-01	2009-10-09	Actavis Group Ptc Ehf
KR100965527B1 (ko)	2008-05-08	2010-06-23	제일약품주식회사	신규(4-(2-(디메틸아미노)-1-(1-하이드록시사이클로헥실)에틸)페녹시)포스페이트 또는 이의 약학적으로 허용가능한 염,이의 제조방법 및 이를 유효성분으로 함유하는 중추신경계질환 예방 및 치료용 조성물
EP2119695A1 (de)	2008-05-16	2009-11-18	Krka	Zubereitung von O-Desmethylvenlafaxin-Salzen
EP2119696A1 (de)	2008-05-16	2009-11-18	Krka	Zubereitung von O-Desmethylvenlafaxin-Salzen
CA2720538A1 (en) *	2008-06-16	2010-01-21	Teva Pharmaceutical Industries Ltd.	Solid states of o-desmethylvenlafaxine salts
AU2009268681B2 (en) *	2008-07-08	2014-10-02	Gilead Sciences, Inc.	Salts of HIV inhibitor compounds
US20100016638A1 (en) *	2008-07-21	2010-01-21	Zdenko Hamersak	Method for preparation of o-desmethylvenlafaxine using polythiolates
US20110263718A1 (en) *	2008-07-30	2011-10-27	Generics [Uk] Limited	Process for the preparation of o-desmethylvenlafaxine
KR101041960B1 (ko) *	2008-08-14	2011-06-16	주식회사 루미맥스테크놀러지	파워 ｌｅｄ를 구비하는 램프 장치
EP2191822A1 (de) *	2008-11-26	2010-06-02	LEK Pharmaceuticals d.d.	Pharmazeutische Zusammensetzungen mit kontrollierter Freisetzung, die O-Desmethylvenlafaxin umfassen
CZ2008756A3 (cs) *	2008-11-27	2010-03-24	Zentiva, A. S.	Zpusob prípravy desvenlafaxinu a jeho solí
ES2343050B1 (es) *	2008-12-16	2011-06-14	Chemo Iberica, S.A.	Procedimiento para la preparacion de desvenlafaxina y sus sales de adicion de acido farmaceuticamente aceptables.
CZ301820B6 (cs) *	2009-02-06	2010-06-30	Zentiva, K.S.	Nové soli desvenlafaxinu a zpusob jejich prípravy
CZ2009454A3 (cs)	2009-07-15	2010-11-10	Zentiva, K. S.	Zpusob prípravy desvenlafaxinu a jeho solí
WO2011007136A2 (en)	2009-07-16	2011-01-20	Cipla Limited	Process for the preparation of o-desmethyl venlafaxine and intermediate for use therein
US20110098506A1 (en) *	2009-10-26	2011-04-28	Intas Pharmaceuticals Limited	Method of preparing o-desmethylvenlafaxine
EP2513041A1 (de)	2009-12-16	2012-10-24	Pharmathen S.A.	Verfahren zur herstellung von o-desmethyl-venlafaxin und salzen daraus
US20110184067A1 (en) *	2010-01-25	2011-07-28	Intas Pharmaceuticals Ltd.	O-desmethylvenlafaxine succinate polymorph & process for preparing thereof
KR101409554B1 (ko) *	2010-03-29	2014-06-19	플리바 흐르바츠카 디.오.오.	Ｏ-데스메틸벤라팍신 푸마레이트의 결정형
CA2792352C (en) *	2010-03-31	2015-06-23	Wockhardt Limited	Modified release dosage form comprising desvenlafaxine or salts thereof
CZ303249B6 (cs)	2010-04-06	2012-06-20	Zentiva, K.S.	Zpusob výroby 4-(2-(substituovaných)-1-(1-hydroxycyklohexyl)ethyl)fenolu O-demethylací jejich methyletheru pomocí nepáchnoucích aromatických thiolu
CN102212014B (zh) *	2010-04-09	2013-12-25	江苏豪森医药集团有限公司	O-去甲基-文拉法辛的谷氨酸盐的晶型、其制备方法及其在医药上的应用
AU2011251747B2 (en)	2010-05-14	2014-08-07	Alembic Limited	Extended release formulations of desvenlafaxine base
CN102249936B (zh) *	2010-05-19	2014-09-17	江苏豪森医药集团有限公司	O-去甲基文拉法辛盐酸盐的水合物及其制备方法
CN103588653B (zh)	2010-10-01	2015-04-22	山东绿叶制药有限公司	4-甲基苯甲酸4-[2-二甲基胺基-1-(1-羟基环己基)乙基]苯酯盐酸盐的多晶型物、制备方法及其应用
US8933123B2 (en)	2010-10-08	2015-01-13	Cadila Healthcare Limited	Polymorphic forms of O-desmethyl-venlafaxine succinate
US20140010883A1 (en)	2011-03-17	2014-01-09	Lupin Limited	Controlled release pharmaceutical compositions of selective serotonin reuptake inhibitor
WO2012140577A1 (en)	2011-04-12	2012-10-18	Lupin Limited	Modified release pharmaceutical compositions of desvenlafaxine
US8481596B2 (en)	2011-06-08	2013-07-09	Lupin Limited	Polymomorph of desvenlafaxine benzoate
UY35091A (es) *	2012-10-24	2014-05-30	Onyx Therapeutics Inc	Formulaciones de liberacion modificada para oprozomib
CN104666291A (zh) *	2013-11-26	2015-06-03	山东绿叶制药有限公司	去甲基文拉法辛苯甲酸酯类化合物在制备改善性功能障碍药物中的应用
CN104352469A (zh) *	2014-11-20	2015-02-18	哈尔滨圣吉药业股份有限公司	一种琥珀酸去甲文拉法辛缓释片及其制备方法
CN106146323B (zh) *	2015-04-03	2021-05-25	石药集团中奇制药技术（石家庄）有限公司	一种琥珀酸去甲文拉法辛一水合物新晶型及制备方法
MX367362B (es)	2016-06-29	2019-08-16	Alparis Sa De Cv	Nuevas formas solidas de desvenlafaxina.
EP3580198B1 (de) *	2017-02-09	2023-08-09	R L Finechem Private Limited	Verfahren zur herstellung of1-[2-(dimethylamino)-1-(4-hydroxyphenyl) ethyl]-cyclohexanol und salzen davon
CN107082745A (zh) *	2017-04-21	2017-08-22	上海华源医药科技发展有限公司	一种改进的ⅰ型去甲文拉法辛琥珀酸盐的生产方法
MX421254B (es) *	2017-07-11	2025-02-10	Universal Stabilization Tech Inc	Método para la conservación de material biológico.
EP3661937B1 (de)	2017-08-01	2021-07-28	Gilead Sciences, Inc.	Kristalline formen von ethyl ((s)-((((2r,5r)-5-(6-amino-9h-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl)oxy)methyl)(phenoxy)phosphoryl)-l-alaninat (gs-9131) zur behandlung von viralen infektionen
EP3666254B1 (de)	2017-08-11	2024-12-04	Amorepacific Corporation	Pharmazeutische zusammensetzung mit (r)-n [1-(3,5-difluor-4-methansulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluormethyl-pyridin-3-yl)-acrylamid
KR102518632B1 (ko)	2018-04-18	2023-04-06	(주)아모레퍼시픽	(r)-n-[1-(3,5-다이플루오로-4-메테인설폰일아미노-페닐)-에틸]-3-(2-프로필-6-트라이플루오로메틸-피리딘-3-일)-아크릴아마이드를 함유하는 약학 조성물
TR201820634A2 (tr)	2018-12-27	2020-07-21	Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi	Desvenlafaksi̇ni̇n kati oral farmasöti̇k kompozi̇syonlari

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3536809A (en)	1969-02-17	1970-10-27	Alza Corp	Medication method
US3598123A (en)	1969-04-01	1971-08-10	Alza Corp	Bandage for administering drugs
US3845770A (en)	1972-06-05	1974-11-05	Alza Corp	Osmatic dispensing device for releasing beneficial agent
US3916899A (en)	1973-04-25	1975-11-04	Alza Corp	Osmotic dispensing device with maximum and minimum sizes for the passageway
US4008719A (en)	1976-02-02	1977-02-22	Alza Corporation	Osmotic system having laminar arrangement for programming delivery of active agent
IE56324B1 (en) *	1982-12-13	1991-06-19	American Home Prod	Phenethylamine derivatives and intermediates therefor
US4535186A (en)	1983-04-19	1985-08-13	American Home Products Corporation	2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
US4761501A (en)	1983-10-26	1988-08-02	American Home Products Corporation	Substituted phenylacetamides
IE58110B1 (en)	1984-10-30	1993-07-14	Elan Corp Plc	Controlled release powder and process for its preparation
US5073543A (en)	1988-07-21	1991-12-17	G. D. Searle & Co.	Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
GB8902209D0 (en)	1989-02-01	1989-03-22	Wyeth John And Brother Limited	Preparation of cyclohexanol derivatives and novel thioamide intermediates
IT1229203B (it)	1989-03-22	1991-07-25	Bioresearch Spa	Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
US5120548A (en)	1989-11-07	1992-06-09	Merck & Co., Inc.	Swelling modulated polymeric drug delivery device
US5733566A (en)	1990-05-15	1998-03-31	Alkermes Controlled Therapeutics Inc. Ii	Controlled release of antiparasitic agents in animals
US5580578A (en)	1992-01-27	1996-12-03	Euro-Celtique, S.A.	Controlled release formulations coated with aqueous dispersions of acrylic polymers
AU4542993A (en)	1992-06-23	1994-01-24	Sepracor, Inc.	Methods and compositions for treating depression and other disorders using optically pure (+) sibutramine
WO1994000114A1 (en)	1992-06-23	1994-01-06	Sepracor Inc.	Methods and compositions for treating depression and other disorders using optically pure (-) sibutramine
US5591767A (en)	1993-01-25	1997-01-07	Pharmetrix Corporation	Liquid reservoir transdermal patch for the administration of ketorolac
PT1738753E (pt)	1993-06-28	2008-06-19	Wyeth Corp	Novos tratamentos utilizando derivados de fenetilamina
TW344661B (en) *	1993-11-24	1998-11-11	Lilly Co Eli	Pharmaceutical composition for treatment of incontinence
EP0667150B1 (de) †	1994-02-14	2002-12-11	Wyeth	Venlafaxin und seine Analoga zum Herbeiführen einer Verbesserung der kognitiven Funktionen
US5594586A (en) *	1994-05-02	1997-01-14	The United States Of America As Represented By The Secretary Of The Air Force	Photorefractive limiting quadratic processor
IT1270594B (it)	1994-07-07	1997-05-07	Recordati Chem Pharm	Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
US5506270A (en) *	1995-01-30	1996-04-09	American Home Products Corporation	Venlafaxine in the treatment of hypothalamic amenorrhea in non-depressed women
US5554383A (en)	1995-04-06	1996-09-10	Trustees Of Tufts College	Veterinary method for clinically modifying the behavior of dogs exhibiting canine affective aggression
US6274171B1 (en)	1996-03-25	2001-08-14	American Home Products Corporation	Extended release formulation of venlafaxine hydrochloride
EP0912577A2 (de) †	1996-05-21	1999-05-06	THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services	Verfahren zur o-demethylierung und entfernung von n-scutzgruppen
CA2306024C (en) †	1997-10-01	2011-04-26	Flemington Pharmaceutical Corporation	Buccal, polar and non-polar spray or capsule
US6197828B1 (en) *	1998-12-01	2001-03-06	Sepracor, Inc.	Derivatives of (+)-venlafaxine and methods of preparing and using the same
US6342533B1 (en)	1998-12-01	2002-01-29	Sepracor, Inc.	Derivatives of (−)-venlafaxine and methods of preparing and using the same
HUP0200898A3 (en)	1999-04-06	2005-09-28	Sepracor Inc	Derivatives of venlafaxine and methods of preparing and using the same
WO2000072827A2 (en) †	1999-05-27	2000-12-07	Acusphere, Inc.	Porous drug matrices and methods of manufacture thereof
AU5738700A (en) *	1999-06-15	2001-01-02	American Home Products Corporation	Enantiomers of o-desmethyl venlafaxine
US20020022662A1 (en)	1999-06-15	2002-02-21	American Home Products Corporation	Enantiomers of O-desmethyl venlafaxine
EP2319826A1 (de) *	2001-02-12	2011-05-11	Wyeth LLC	O-Desmethyl-Venlafaxine Succinat Salz
UA80543C2 (en) *	2001-12-04	2007-10-10	Wyeth Corp	Method for the preparation of o-desmethylvenlafaxine
AU2003247515A1 (en)	2002-06-10	2003-12-22	Wyeth	Novel formate salt of o-desmethyl-venlafaxine
TWI306092B (en)	2003-03-11	2009-02-11	Wyeth Corp	Process for preparation of phenethylamine derivatives
CN1917860A (zh)	2004-02-06	2007-02-21	惠氏公司	多颗粒o－去甲基文拉法辛盐及其用途

2002
- 2002-02-11 EP EP10177304A patent/EP2319826A1/de not_active Withdrawn
- 2002-02-11 CA CA002666611A patent/CA2666611A1/en not_active Abandoned
- 2002-02-11 WO PCT/US2002/004103 patent/WO2002064543A2/en not_active Ceased
- 2002-02-11 HU HU0303128A patent/HUP0303128A3/hu unknown
- 2002-02-11 US US10/073,743 patent/US6673838B2/en not_active Expired - Lifetime
- 2002-02-11 CN CN200910206182A patent/CN101671260A/zh active Pending
- 2002-02-11 NZ NZ539791A patent/NZ539791A/en not_active IP Right Cessation
- 2002-02-11 EP EP02718949.7A patent/EP1360169B2/de not_active Expired - Lifetime
- 2002-02-11 EA EA200300873A patent/EA011451B1/ru not_active IP Right Cessation
- 2002-02-11 PT PT02718949T patent/PT1360169E/pt unknown
- 2002-02-11 AT AT02718949T patent/ATE369330T1/de active
- 2002-02-11 HN HN2002000030A patent/HN2002000030A/es unknown
- 2002-02-11 JP JP2002564477A patent/JP4220243B2/ja not_active Expired - Lifetime
- 2002-02-11 DE DE60221642.7T patent/DE60221642T3/de not_active Expired - Lifetime
- 2002-02-11 BR BR0207157-6A patent/BR0207157A/pt not_active Application Discontinuation
- 2002-02-11 AU AU2002250058A patent/AU2002250058B2/en not_active Expired
- 2002-02-11 KR KR1020037010561A patent/KR100875610B1/ko not_active Expired - Lifetime
- 2002-02-11 PL PL364605A patent/PL211788B1/pl unknown
- 2002-02-11 CN CNB028081129A patent/CN100567253C/zh not_active Expired - Lifetime
- 2002-02-11 DK DK02718949T patent/DK1360169T3/da active
- 2002-02-11 IL IL15734002A patent/IL157340A0/xx unknown
- 2002-02-11 SI SI200230609T patent/SI1360169T1/sl unknown
- 2002-02-11 EP EP07014868A patent/EP1864967A1/de not_active Withdrawn
- 2002-02-11 ES ES02718949.7T patent/ES2290281T5/es not_active Expired - Lifetime
- 2002-02-11 MX MXPA03007043A patent/MXPA03007043A/es active IP Right Grant
- 2002-02-11 PL PL396568A patent/PL212943B1/pl unknown
- 2002-02-11 PE PE2002000105A patent/PE20020877A1/es active IP Right Grant
- 2002-02-11 CA CA002436668A patent/CA2436668C/en not_active Expired - Lifetime
- 2002-02-12 AR ARP020100463A patent/AR032671A1/es not_active Application Discontinuation
- 2002-02-13 UY UY27175A patent/UY27175A1/es active IP Right Grant
- 2002-02-14 PA PA20028539901A patent/PA8539901A1/es unknown
- 2002-02-15 TW TW091102559A patent/TWI318201B/zh not_active IP Right Cessation
2003
- 2003-08-11 NO NO20033538A patent/NO328807B1/no not_active IP Right Cessation
- 2003-08-11 IL IL157340A patent/IL157340A/en active IP Right Grant
- 2003-09-04 US US10/654,756 patent/US20040044241A1/en not_active Abandoned
- 2003-09-11 ZA ZA2003/07116A patent/ZA200307116B/en unknown
2004
- 2004-11-10 US US10/985,292 patent/US7026508B2/en not_active Expired - Fee Related
2006
- 2006-01-18 US US11/334,223 patent/US7291347B2/en not_active Expired - Lifetime
2007
- 2007-08-20 US US11/841,638 patent/US20090018208A1/en not_active Abandoned
- 2007-10-22 CY CY20071101362T patent/CY1106952T1/el unknown
2009
- 2009-08-05 IL IL200255A patent/IL200255A/en active IP Right Grant
2010
- 2010-11-18 IL IL209444A patent/IL209444A/en active IP Right Grant
2011
- 2011-07-01 AR ARP110102372A patent/AR082076A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
EA200300873A1 (ru)	2003-12-25
AR032671A1 (es)	2003-11-19
HK1057885A1 (en)	2004-04-23
CA2436668A1 (en)	2002-08-22
ES2290281T5 (es)	2017-09-11
PL364605A1 (en)	2004-12-13
MXPA03007043A (es)	2003-11-18
WO2002064543A2 (en)	2002-08-22
ZA200307116B (en)	2005-02-23
US7026508B2 (en)	2006-04-11
DE60221642T3 (de)	2017-10-26
IL200255A (en)	2010-12-30
KR100875610B1 (ko)	2008-12-26
DE60221642T2 (de)	2008-05-21
EP1864967A1 (de)	2007-12-12
AU2002250058B2 (en)	2007-08-16
NO20033538D0 (no)	2003-08-11
WO2002064543A3 (en)	2002-12-12
ES2290281T3 (es)	2008-02-16
CN101671260A (zh)	2010-03-17
PL211788B1 (pl)	2012-06-29
IL157340A (en)	2010-04-15
US20070037884A1 (en)	2007-02-15
PL396568A1 (pl)	2012-02-13
NO328807B1 (no)	2010-05-18
TWI318201B (en)	2009-12-11
UY27175A1 (es)	2002-09-30
CY1106952T1 (el)	2012-09-26
CA2436668C (en)	2009-05-26
CA2666611A1 (en)	2002-08-22
JP4220243B2 (ja)	2009-02-04
AR082076A2 (es)	2012-11-07
PL212943B1 (pl)	2012-12-31
US7291347B2 (en)	2007-11-06
NZ539791A (en)	2006-11-30
DE60221642D1 (en)	2007-09-20
PE20020877A1 (es)	2002-11-12
US6673838B2 (en)	2004-01-06
IL209444A (en)	2012-10-31
HUP0303128A2 (hu)	2003-12-29
CN1501909A (zh)	2004-06-02
DK1360169T3 (da)	2007-11-26
BR0207157A (pt)	2004-02-17
KR20030077614A (ko)	2003-10-01
EP1360169B2 (de)	2017-05-24
JP2004529877A (ja)	2004-09-30
IL209444A0 (en)	2011-07-31
EA011451B1 (ru)	2009-04-28
ATE369330T1 (de)	2007-08-15
US20050096479A1 (en)	2005-05-05
US20090018208A1 (en)	2009-01-15
US20040044241A1 (en)	2004-03-04
NO20033538L (no)	2003-08-11
HN2002000030A (es)	2004-06-07
SI1360169T1 (sl)	2007-12-31
CN100567253C (zh)	2009-12-09
US20030045583A1 (en)	2003-03-06
HUP0303128A3 (en)	2008-03-28
EP1360169A2 (de)	2003-11-12
EP2319826A1 (de)	2011-05-11
PT1360169E (pt)	2007-10-29
EP1360169B1 (de)	2007-08-08
PA8539901A1 (es)	2005-05-10

Publication	Publication Date	Title
TWI318201B (en)	2009-12-11	Novel succinate salt of o-desmethyl-venlafaxine
PT1438306E (pt)	2014-06-03	Derivados de uk-20
IL158388A0 (en)	2004-05-12	Novel arylheteroalkylamine derivatives
IL157426A0 (en)	2004-03-28	Peg-conjugates of hgf-nk4
HUP0500734A3 (en)	2005-12-28	Use of 2-alkoxyphenyl-substituted imidazotriazinones
GB0104259D0 (en)	2001-04-11	Novel compounds
IL161178A0 (en)	2004-08-31	MODIFICATIONS OF SOLID 3-sn-PHOSPHOGLYCERIDES
AU2003298725A8 (en)	2004-06-23	Preparation of metallotexaphyrins
TW493722U (en)	2002-07-01	Improved structure of lampwick
IL156839A0 (en)	2004-02-08	Use of chromanes
HU0104370D0 (en)	2001-12-28	Honeyed schnaps of oerseg
PL346451A1 (en)	2002-09-23	Novel derivative of l-homophenylamine
IL165356A0 (en)	2006-01-15	Preparation of 4-haloalkylkylnicotinamides
TW526778U (en)	2003-04-01	Structure of dual-purposed shoes
PL351273A1 (en)	2003-06-30	Novel derivatives of benzoimidazole
PL356853A1 (en)	2004-05-17	Application of bacteriphages
TW470115U (en)	2001-12-21	Hinge of micro-turning type
TW510530U (en)	2002-11-11	New structure of micro-radiator
TW511737U (en)	2002-11-21	New structure of micro-radiator
TW510531U (en)	2002-11-11	New structure of micro-radiator
GB0109520D0 (en)	2001-06-06	Use of (di-substituted-phenyl)-pyrimidinyl-imidazole derivatives as njk-inhibitors
GB0125482D0 (en)	2001-12-12	Uses of (s)-clenbuterol
TW494780U (en)	2002-07-11	Structure of swimmeret
PL348897A1 (en)	2003-01-27	Novel compound - derivative of indane
TW552879U (en)	2003-09-11	Improved structure of hairclip