IL158412A0 - A method for increasing the compactability of an active ingredient and a process for producing a solid dosage form having a high active ingredient drug load - Google Patents

A method for increasing the compactability of an active ingredient and a process for producing a solid dosage form having a high active ingredient drug load

Info

Publication number: IL158412A0
Authority: IL; Israel
Prior art keywords: active ingredient; compactability; producing; increasing; dosage form
Prior art date: 2001-04-26

Application number

IL15841202A

Other languages

English (en)

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-26

Filing date

2002-04-23

Publication date

2004-05-12

2002-04-23 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

2004-05-12 Publication of IL158412A0 publication Critical patent/IL158412A0/xx

Links

239000004480 active ingredient Substances 0.000 title 2
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
239000007909 solid dosage form Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Immunology (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Dermatology (AREA)
Hematology (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Virology (AREA)
Ophthalmology & Optometry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Rheumatology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Inorganic Chemistry (AREA)
Reproductive Health (AREA)
Vascular Medicine (AREA)
Molecular Biology (AREA)
Psychiatry (AREA)

IL15841202A 2001-04-26 2002-04-23 A method for increasing the compactability of an active ingredient and a process for producing a solid dosage form having a high active ingredient drug load IL158412A0 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US28687001P	2001-04-26	2001-04-26
US28668201P	2001-04-26	2001-04-26
PCT/US2002/013055 WO2002088664A2 (en)	2001-04-26	2002-04-23	Control of compactability through crystallization

Publications (1)

Publication Number	Publication Date
IL158412A0 true IL158412A0 (en)	2004-05-12

Family

ID=26964005

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL15841202A IL158412A0 (en)	2001-04-26	2002-04-23	A method for increasing the compactability of an active ingredient and a process for producing a solid dosage form having a high active ingredient drug load
IL15823502A IL158235A0 (en)	2001-04-26	2002-04-23	A pharmaceutical tablet having high sulfhydryl-based matrix metalloproteinase inhibitor content

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL15823502A IL158235A0 (en)	2001-04-26	2002-04-23	A pharmaceutical tablet having high sulfhydryl-based matrix metalloproteinase inhibitor content

Country Status (13)

Country	Link
US (2)	US20040175419A1 (cs)
EP (2)	EP1390018A1 (cs)
JP (2)	JP2005505501A (cs)
KR (1)	KR20040036686A (cs)
CN (2)	CN1523981A (cs)
BR (2)	BR0209199A (cs)
CA (2)	CA2445290A1 (cs)
CZ (2)	CZ20032902A3 (cs)
HU (2)	HUP0303860A3 (cs)
IL (2)	IL158412A0 (cs)
MX (2)	MXPA03009676A (cs)
PL (2)	PL367262A1 (cs)
WO (2)	WO2002087548A1 (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK1243262T3 (da)	2001-03-20	2006-10-02	Sanol Arznei Schwarz Gmbh	Hidtil ukendt anvendelse af en peptidklasse af forbindelser til behandling af ikke-neuropatiske, inflammatoriske smerter
ES2185606T3 (es)	2001-03-21	2003-05-01	Sanol Arznei Schwarz Gmbh	Nuevo uso de una clase de compuestos peptidicos para tratamiento de la alodinia u otros tipos diferentes de dolor cronico o fantasma.
GB0513881D0 (en)	2005-07-06	2005-08-10	Btg Int Ltd	Core 2 GLCNAC-T Inhibitors III
GB0329667D0 (en)	2003-12-22	2004-01-28	King S College London	Core 2 GlcNAc-T inhibitor
US20080182801A1 (en)	2003-12-22	2008-07-31	Btg International Limited	Core 2 glcnac-t inhibitors
EP1604656A1 (en)	2004-06-09	2005-12-14	Schwarz Pharma Ag	Novel use of peptide compounds for treating amyotrophic lateral sclerosis (ALS)
PL1781276T3 (pl)	2004-08-27	2010-11-30	Ucb Pharma Gmbh	Zastosowanie związków peptydowych do leczenia bólu związanego z rakiem kości, bólu indukowanego przez chemioterapię oraz nukleozydy
GB0513888D0 (en)	2005-07-06	2005-08-10	Btg Int Ltd	Core 2 GLCNAC-T Inhibitors II
GB0513883D0 (en)	2005-07-06	2005-08-10	Btg Int Ltd	Diagnosis of Atherosclerosis
WO2007144195A2 (en)	2006-06-15	2007-12-21	Schwarz Pharma Ag	Pharmaceutical composition with synergistic anticonvulsant effect
GB0722484D0 (en) *	2007-11-15	2007-12-27	Ucl Business Plc	Solid compositions
WO2011156061A1 (en)	2010-06-07	2011-12-15	Telik, Inc.	Preparation of crystalline ezatiostat hydrochloride ansolvate form d
EP2576591A2 (en) *	2010-06-07	2013-04-10	Telik, Inc.	Tablet formulation of ezatiostat

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4476248A (en) *	1983-02-28	1984-10-09	The Upjohn Company	Crystallization of ibuprofen
ES2150438T3 (es) *	1991-12-30	2000-12-01	Fmc Corp	Composicion de esferonizacion a base de celulosa microcristalina.
WO1997012902A1 (en) *	1995-10-05	1997-04-10	Darwin Discovery Limited	Thio-substituted peptides as inhibitors for metalloproteinases and tnf liberation

2002
- 2002-04-23 CA CA002445290A patent/CA2445290A1/en not_active Abandoned
- 2002-04-23 BR BR0209199-2A patent/BR0209199A/pt unknown
- 2002-04-23 JP JP2002585919A patent/JP2005505501A/ja active Pending
- 2002-04-23 US US10/475,959 patent/US20040175419A1/en not_active Abandoned
- 2002-04-23 EP EP02723952A patent/EP1390018A1/en not_active Withdrawn
- 2002-04-23 HU HU0303860A patent/HUP0303860A3/hu unknown
- 2002-04-23 CZ CZ20032902A patent/CZ20032902A3/cs unknown
- 2002-04-23 PL PL02367262A patent/PL367262A1/xx not_active Application Discontinuation
- 2002-04-23 MX MXPA03009676A patent/MXPA03009676A/es unknown
- 2002-04-23 KR KR10-2003-7013698A patent/KR20040036686A/ko not_active Withdrawn
- 2002-04-23 WO PCT/US2002/012915 patent/WO2002087548A1/en not_active Ceased
- 2002-04-23 BR BR0209155-0A patent/BR0209155A/pt not_active Application Discontinuation
- 2002-04-23 IL IL15841202A patent/IL158412A0/xx unknown
- 2002-04-23 CN CNA028089944A patent/CN1523981A/zh active Pending
- 2002-04-23 HU HU0400377A patent/HUP0400377A2/hu unknown
- 2002-04-23 CN CNA02812779XA patent/CN1520283A/zh active Pending
- 2002-04-23 IL IL15823502A patent/IL158235A0/xx unknown
- 2002-04-23 CA CA002445702A patent/CA2445702A1/en not_active Abandoned
- 2002-04-23 WO PCT/US2002/013055 patent/WO2002088664A2/en not_active Ceased
- 2002-04-23 JP JP2002584894A patent/JP2004530679A/ja not_active Withdrawn
- 2002-04-23 MX MXPA03009689A patent/MXPA03009689A/es unknown
- 2002-04-23 US US10/476,047 patent/US20040208924A1/en not_active Abandoned
- 2002-04-23 EP EP02728982A patent/EP1390011A2/en not_active Withdrawn
- 2002-04-23 PL PL02373548A patent/PL373548A1/xx not_active Application Discontinuation
- 2002-04-23 CZ CZ20032901A patent/CZ20032901A3/cs unknown

Also Published As

Publication number	Publication date
IL158235A0 (en)	2004-05-12
WO2002087548A1 (en)	2002-11-07
WO2002088664A2 (en)	2002-11-07
PL367262A1 (en)	2005-02-21
KR20040036686A (ko)	2004-04-30
JP2005505501A (ja)	2005-02-24
BR0209155A (pt)	2004-10-05
CN1520283A (zh)	2004-08-11
PL373548A1 (en)	2005-09-05
MXPA03009676A (es)	2004-02-12
CN1523981A (zh)	2004-08-25
HUP0400377A2 (en)	2007-09-28
HUP0303860A3 (en)	2005-05-30
JP2004530679A (ja)	2004-10-07
CZ20032902A3 (cs)	2004-01-14
WO2002088664A3 (en)	2003-08-21
MXPA03009689A (es)	2004-02-12
CZ20032901A3 (en)	2004-07-14
US20040175419A1 (en)	2004-09-09
CA2445702A1 (en)	2002-11-07
EP1390011A2 (en)	2004-02-25
BR0209199A (pt)	2006-02-07
CA2445290A1 (en)	2002-11-07
HUP0303860A2 (hu)	2004-03-29
US20040208924A1 (en)	2004-10-21
EP1390018A1 (en)	2004-02-25

Publication	Publication Date	Title
HUP0003121A3 (en)	2001-03-28	Method for producing orally administered, solid pharmaceutical products with controlled release of the active substance
HUP0204170A3 (en)	2005-03-29	5-thia-omega-substituted phenyl-prostaglandin e derivatives, process for producing the same and drugs containing the same as the active ingredient
HUP0301325A3 (en)	2004-03-01	Stabilized pharmaceutically effective composition and pharmaceutical composition comprising the same and process for preparation the composition
SI1417206T1 (sl)	2010-09-30	Novi H piridazin onski derivati farmacevtski sestavki ki jih vsebujejo in postopek za pripravo aktivne sestavine
AU2002358270A1 (en)	2003-07-09	Zero-order sustained released dosage forms and method of making the same
HUP0303891A3 (en)	2010-01-28	Pharmaceutically active piridine derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0401963A3 (en)	2006-01-30	Carboxylic acid derivative compounds and drugs comprising these compounds as the active ingredient
IL158412A0 (en)	2004-05-12	A method for increasing the compactability of an active ingredient and a process for producing a solid dosage form having a high active ingredient drug load
AU2002342755A1 (en)	2003-04-14	Method and device for producing granulates that comprise at least one pharmaceutical active substance
HRP20030858A2 (en)	2005-08-31	Method for manufacturing a low dose pharmaceutical composition having uniform drug distribution and potency
IL159217A0 (en)	2004-06-01	An oral pharmaceutical formulation comprising a basic pharmaceutically active ingredient having ph-dependent solubility, a process for the manufacture thereof and use thereof in medicine
HUP0400155A3 (en)	2007-05-02	N-phenylarylsulfonamide compound, drug containing the compound as active ingredient, intermediate for the compound, and processes for producing the same
IL150528A0 (en)	2003-02-12	Ibuprofen containing active agent preparation
NZ515644A (en)	2004-12-24	Oil-core compositions for the sustained release of hydrophobic drugs
AU2002238855A1 (en)	2003-03-20	N-phenylarylsulfonamide compound, drug containing the compound as active ingredient, intermediate for the compound, and processes for producing the same
HUP0302050A3 (en)	2012-11-28	Pharmaceutical form of administration for peptides, method for its production and use
SG116507A1 (en)	2005-11-28	Pharmaceutical dosage form and method of making.
AU2002234545A1 (en)	2002-06-18	Pharmaceutical preparation in the form of a suspension comprising an acid-labileactive ingredient
IL161983A0 (en)	2005-11-20	Preparation compositions containing acid-unstable physiologically active compounds, and process for producing the same
WO2005004860A3 (fr)	2005-04-14	Nouvelle composition pharmaceutique solide comprenant de l'amisulpride
AU2003302188A8 (en)	2004-07-22	Method of obtaining a soothing active ingredient, active ingredient and compositions obtained
CA2495527A1 (en)	2004-02-12	New sexual-dysfunction-compound-containing rapid-onset pharmaceutical formulations comprising cocoa powder and use thereof
HUP0203443A3 (en)	2003-12-29	Novel contraceptive medicament and method for producing the same
ZA200303276B (en)	2004-04-21	Stable pharmaceutical form of an anticancer drug and method for production of stable pharmaceutical form of an anticancer drug.
AU2001282071A1 (en)	2002-03-22	Multiparticulate pharmaceutical dosage form and a method for producing the same