IL165007A0 - Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis - Google Patents

Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis

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Publication number
IL165007A0
IL165007A0 IL16500704A IL16500704A IL165007A0 IL 165007 A0 IL165007 A0 IL 165007A0 IL 16500704 A IL16500704 A IL 16500704A IL 16500704 A IL16500704 A IL 16500704A IL 165007 A0 IL165007 A0 IL 165007A0
Authority
IL
Israel
Prior art keywords
methods
apoptosis
polypeptides
nucleic acids
compositions
Prior art date
Application number
IL16500704A
Other languages
English (en)
Original Assignee
Senesco Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/141,647 external-priority patent/US7166467B2/en
Application filed by Senesco Technologies Inc filed Critical Senesco Technologies Inc
Publication of IL165007A0 publication Critical patent/IL165007A0/xx

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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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    • C07K14/4747—Apoptosis related proteins
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    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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IL16500704A 2002-05-07 2004-11-03 Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis IL165007A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/141,647 US7166467B2 (en) 2001-07-23 2002-05-07 Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis
US10/200,148 US7968523B2 (en) 2001-07-23 2002-07-23 Method for inducing apoptosis using apoptosis-specific EIF5-A
PCT/US2003/014049 WO2003095613A2 (en) 2002-05-07 2003-05-07 Nucleic acids, polypeptides, and methods for modulating apoptosis

Publications (1)

Publication Number Publication Date
IL165007A0 true IL165007A0 (en) 2005-12-18

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Application Number Title Priority Date Filing Date
IL16500704A IL165007A0 (en) 2002-05-07 2004-11-03 Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis

Country Status (10)

Country Link
US (3) US7968523B2 (de)
EP (1) EP1509251B1 (de)
KR (1) KR20050007383A (de)
AT (1) ATE387220T1 (de)
AU (1) AU2003234482C1 (de)
CA (1) CA2484144A1 (de)
DE (1) DE60319369D1 (de)
IL (1) IL165007A0 (de)
NZ (1) NZ536958A (de)
WO (1) WO2003095613A2 (de)

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Publication number Priority date Publication date Assignee Title
US7166467B2 (en) * 2001-07-23 2007-01-23 Senesco Technologies, Inc. Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis
US7381708B2 (en) 2001-07-23 2008-06-03 Sensco Technologies, Inc. Suppression of eIF5A1 expression by the use of antisense oligonucleotides for the prevention of retinal cell death in the glaucomatous eye
US7968523B2 (en) * 2001-07-23 2011-06-28 Senesco Technologies, Inc. Method for inducing apoptosis using apoptosis-specific EIF5-A
US7595308B2 (en) * 2002-11-18 2009-09-29 Grenpharma Llc Compositions for treating and/or preventing diseases characterized by the presence of metal ions
WO2004078940A2 (en) * 2003-03-05 2004-09-16 Senesco Technologies, Inc. USE OF ANTISENSE OLIGONUCLEOTIDES OR siRNA TO SUPPRESS EXPRESSION OF eIF-5A1
NZ544159A (en) * 2003-06-06 2009-04-30 Senesco Technologies Inc Inhibition of apoptosis-specific eIF-5A ("eIF-5A1") with antisense oligonucleotides and siRNAs as anti-inflammatory therapeutics
WO2005009445A1 (en) * 2003-07-22 2005-02-03 Cv Therapeutics, Inc. A1 adenosine receptor antagonists
US20140371299A1 (en) * 2004-06-07 2014-12-18 Senesco Technologies, Inc. Use of Apoptosis-Specific elF-5A siRNA to Down Regulate Expression of Proinflammatory Cytokines to Treat Sepsis
TW200615001A (en) * 2004-07-20 2006-05-16 Senesco Technologies Inc Use of apoptosis-specific eIF-5A siRNAs and antisense polynucleotides to inhibit/suppress an inflammatory response
WO2006047477A1 (en) * 2004-10-22 2006-05-04 Grenpharama Llc Compositions for treating and/or preventing diseases characterized by the presence of the metal ions
EP1959010A3 (de) * 2004-12-03 2009-02-25 Senesco Technologies, Inc. Apoptosespezifisches eIF-5A und Polynukleotide zu seiner Kodierung
WO2006060699A2 (en) * 2004-12-03 2006-06-08 Senesco Technologies, Inc. Methods of increasing seed yield
NZ569075A (en) * 2005-12-13 2011-12-22 Senesco Technologies Inc Use of elF-5A to kill multiple myeloma cells
NZ596310A (en) * 2006-03-20 2013-05-31 Senesco Technologies Inc A novel method of protecting islet cells from apoptosis during the donor harvesting process
CN102124108A (zh) * 2007-08-20 2011-07-13 森尼斯科技术公司 Eif-5a1 sirna保护胰岛细胞免受凋亡和维持它们功能性的用途
JP5578522B2 (ja) 2008-05-27 2014-08-27 義規 世古 アポトーシス誘導薬

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US5168064A (en) 1990-04-20 1992-12-01 The Regents Of The University Of California Endo-1,4-β-glucanase gene and its use in plants
US5344846A (en) 1992-12-30 1994-09-06 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for inhibiting deoxyhypusine synthase and the growth of cells
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WO2003095613A3 (en) 2004-10-28
ATE387220T1 (de) 2008-03-15
US20030050272A1 (en) 2003-03-13
US7968523B2 (en) 2011-06-28
KR20050007383A (ko) 2005-01-17
NZ536958A (en) 2005-12-23
CA2484144A1 (en) 2003-11-20
DE60319369D1 (de) 2008-04-10
EP1509251B1 (de) 2008-02-27
AU2003234482A1 (en) 2003-11-11
WO2003095613A2 (en) 2003-11-20
EP1509251A2 (de) 2005-03-02
US20140212969A1 (en) 2014-07-31
AU2003234482B2 (en) 2008-07-31
EP1509251A4 (de) 2005-08-10
US20110288156A1 (en) 2011-11-24

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