IL167724A - Kahalalide derivatives and pharmaceutical compositions containing the same - Google Patents
Kahalalide derivatives and pharmaceutical compositions containing the sameInfo
- Publication number
- IL167724A IL167724A IL167724A IL16772405A IL167724A IL 167724 A IL167724 A IL 167724A IL 167724 A IL167724 A IL 167724A IL 16772405 A IL16772405 A IL 16772405A IL 167724 A IL167724 A IL 167724A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- kahalalide
- cancer
- val
- compound according
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB2002/004735 WO2003033012A1 (en) | 2001-10-19 | 2002-10-18 | Kahalalide compounds for use in cancer therapy |
| GBGB0304367.6A GB0304367D0 (en) | 2003-02-26 | 2003-02-26 | Methods for treating psoriasis |
| GB0314725A GB0314725D0 (en) | 2003-06-24 | 2003-06-24 | New antitumoral compounds |
| PCT/US2003/033207 WO2004035613A2 (en) | 2002-10-18 | 2003-10-20 | 4-methylhexanoic kahalaide f compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL167724A true IL167724A (en) | 2012-01-31 |
Family
ID=35276268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL167724A IL167724A (en) | 2002-10-18 | 2005-03-29 | Kahalalide derivatives and pharmaceutical compositions containing the same |
Country Status (13)
| Country | Link |
|---|---|
| KR (2) | KR101149095B1 (pl) |
| AT (1) | ATE490975T1 (pl) |
| AU (1) | AU2003285911B2 (pl) |
| CA (1) | CA2501089C (pl) |
| CY (1) | CY1111319T1 (pl) |
| DE (1) | DE60335292D1 (pl) |
| DK (1) | DK1572726T3 (pl) |
| ES (1) | ES2357644T3 (pl) |
| IL (1) | IL167724A (pl) |
| NO (1) | NO333448B1 (pl) |
| PL (1) | PL209129B1 (pl) |
| PT (1) | PT1572726E (pl) |
| SI (1) | SI1572726T1 (pl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0321066D0 (en) * | 2003-09-09 | 2003-10-08 | Pharma Mar Sau | New antitumoral compounds |
| GB0408958D0 (en) * | 2004-04-22 | 2004-05-26 | Pharma Mar Sa | Convergent synthesis for kahalalide compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9302046D0 (en) * | 1993-02-03 | 1993-03-24 | Pharma Mar Sa | Antiumoral compound-v |
| NZ525243A (en) * | 2000-10-31 | 2005-01-28 | Pharma Mar S | A lyophilised formulation comprising kahalalide F, a peptide isolated from a herbivorous marine species of mollusc, Elysia rufescens, to treat cancer |
| EP1435990A1 (en) * | 2001-10-19 | 2004-07-14 | Pharma Mar, S.A. | Kahalalide compounds for use in cancer therapy |
-
2003
- 2003-10-20 KR KR1020057006480A patent/KR101149095B1/ko not_active Expired - Fee Related
- 2003-10-20 DK DK03779140.7T patent/DK1572726T3/da active
- 2003-10-20 CA CA2501089A patent/CA2501089C/en not_active Expired - Fee Related
- 2003-10-20 PT PT03779140T patent/PT1572726E/pt unknown
- 2003-10-20 AU AU2003285911A patent/AU2003285911B2/en not_active Ceased
- 2003-10-20 DE DE60335292T patent/DE60335292D1/de not_active Expired - Lifetime
- 2003-10-20 KR KR1020117020121A patent/KR20110114690A/ko not_active Ceased
- 2003-10-20 ES ES03779140T patent/ES2357644T3/es not_active Expired - Lifetime
- 2003-10-20 SI SI200331948T patent/SI1572726T1/sl unknown
- 2003-10-20 PL PL377056A patent/PL209129B1/pl unknown
- 2003-10-20 AT AT03779140T patent/ATE490975T1/de active
-
2005
- 2005-03-29 IL IL167724A patent/IL167724A/en not_active IP Right Cessation
- 2005-05-13 NO NO20052379A patent/NO333448B1/no not_active IP Right Cessation
-
2011
- 2011-03-08 CY CY20111100265T patent/CY1111319T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20050070056A (ko) | 2005-07-05 |
| CY1111319T1 (el) | 2015-08-05 |
| ES2357644T3 (es) | 2011-04-28 |
| DK1572726T3 (da) | 2011-03-28 |
| PL377056A1 (pl) | 2006-01-23 |
| CA2501089C (en) | 2012-07-17 |
| PT1572726E (pt) | 2011-02-14 |
| PL209129B1 (pl) | 2011-07-29 |
| ATE490975T1 (de) | 2010-12-15 |
| KR20110114690A (ko) | 2011-10-19 |
| NO20052379D0 (no) | 2005-05-13 |
| AU2003285911A1 (en) | 2004-05-04 |
| NO333448B1 (no) | 2013-06-10 |
| KR101149095B1 (ko) | 2012-05-30 |
| NO20052379L (no) | 2005-07-15 |
| DE60335292D1 (de) | 2011-01-20 |
| HK1082261A1 (en) | 2006-06-02 |
| CA2501089A1 (en) | 2004-04-29 |
| AU2003285911B2 (en) | 2009-11-19 |
| SI1572726T1 (sl) | 2011-04-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7683028B2 (en) | Kahalalide compositions | |
| JP5372096B2 (ja) | 新規な抗腫瘍化合物 | |
| EP1572726B1 (en) | 4-methylhexanoic kahalalide f compound | |
| RU2356908C2 (ru) | Новые противоопухолевые соединения | |
| CA2501089C (en) | 4-methylhexanoic kahalaide f compound | |
| HK1082261B (en) | 4-methylhexanoic kahalalide f compound |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |