IL193599A - METHOD AND SYSTEM FOR DETERMINING SEQUENCE INFORMATION FOR A POLLINOUTIDE PURPOSE - Google Patents
METHOD AND SYSTEM FOR DETERMINING SEQUENCE INFORMATION FOR A POLLINOUTIDE PURPOSEInfo
- Publication number
- IL193599A IL193599A IL193599A IL19359908A IL193599A IL 193599 A IL193599 A IL 193599A IL 193599 A IL193599 A IL 193599A IL 19359908 A IL19359908 A IL 19359908A IL 193599 A IL193599 A IL 193599A
- Authority
- IL
- Israel
- Prior art keywords
- sequence information
- target polynucleotide
- determining sequence
- determining
- polynucleotide
- Prior art date
Links
- 102000040430 polynucleotide Human genes 0.000 title 1
- 108091033319 polynucleotide Proteins 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77641506P | 2006-02-24 | 2006-02-24 | |
| PCT/US2007/062825 WO2007133831A2 (fr) | 2006-02-24 | 2007-02-26 | Séquençage génomique à haut débit sur des puces à adn |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL193599A0 IL193599A0 (en) | 2009-05-04 |
| IL193599A true IL193599A (en) | 2015-06-30 |
Family
ID=38694571
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL193599A IL193599A (en) | 2006-02-24 | 2008-08-21 | METHOD AND SYSTEM FOR DETERMINING SEQUENCE INFORMATION FOR A POLLINOUTIDE PURPOSE |
| IL238895A IL238895B (en) | 2006-02-24 | 2015-05-19 | High-throughput sequencing of genomes on DNA arrays |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL238895A IL238895B (en) | 2006-02-24 | 2015-05-19 | High-throughput sequencing of genomes on DNA arrays |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8722326B2 (fr) |
| EP (2) | EP1994180A4 (fr) |
| JP (2) | JP5180845B2 (fr) |
| CN (1) | CN101432439B (fr) |
| AU (1) | AU2007249635B2 (fr) |
| CA (1) | CA2643700A1 (fr) |
| IL (2) | IL193599A (fr) |
| WO (1) | WO2007133831A2 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11414702B2 (en) | 2005-06-15 | 2022-08-16 | Complete Genomics, Inc. | Nucleic acid analysis by random mixtures of non-overlapping fragments |
Families Citing this family (238)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2624896C (fr) * | 2005-10-07 | 2017-11-07 | Callida Genomics, Inc. | Biopuces a molecules simples autoassemblees et utilisations |
| US7960104B2 (en) * | 2005-10-07 | 2011-06-14 | Callida Genomics, Inc. | Self-assembled single molecule arrays and uses thereof |
| SG170028A1 (en) * | 2006-02-24 | 2011-04-29 | Callida Genomics Inc | High throughput genome sequencing on dna arrays |
| US7910354B2 (en) * | 2006-10-27 | 2011-03-22 | Complete Genomics, Inc. | Efficient arrays of amplified polynucleotides |
| US20080221832A1 (en) * | 2006-11-09 | 2008-09-11 | Complete Genomics, Inc. | Methods for computing positional base probabilities using experminentals base value distributions |
| US20090111706A1 (en) * | 2006-11-09 | 2009-04-30 | Complete Genomics, Inc. | Selection of dna adaptor orientation by amplification |
| US11940413B2 (en) | 2007-02-05 | 2024-03-26 | IsoPlexis Corporation | Methods and devices for sequencing nucleic acids in smaller batches |
| EP2201136B1 (fr) | 2007-10-01 | 2017-12-06 | Nabsys 2.0 LLC | Séquençage par nanopore et hybridation de sondes pour former des complexes ternaires et l'alignement de plage variable |
| US8951731B2 (en) * | 2007-10-15 | 2015-02-10 | Complete Genomics, Inc. | Sequence analysis using decorated nucleic acids |
| US7897344B2 (en) * | 2007-11-06 | 2011-03-01 | Complete Genomics, Inc. | Methods and oligonucleotide designs for insertion of multiple adaptors into library constructs |
| US8298768B2 (en) * | 2007-11-29 | 2012-10-30 | Complete Genomics, Inc. | Efficient shotgun sequencing methods |
| US8518640B2 (en) * | 2007-10-29 | 2013-08-27 | Complete Genomics, Inc. | Nucleic acid sequencing and process |
| US8415099B2 (en) | 2007-11-05 | 2013-04-09 | Complete Genomics, Inc. | Efficient base determination in sequencing reactions |
| CN101910399B (zh) | 2007-10-30 | 2015-11-25 | 考利达基因组股份有限公司 | 用于核酸高通量测序的装置 |
| WO2009061840A1 (fr) * | 2007-11-05 | 2009-05-14 | Complete Genomics, Inc. | Procédés et conceptions d'oligonucléotide pour une insertion d'adaptateurs multiples en utilisant une méthylation sélective |
| US8592150B2 (en) | 2007-12-05 | 2013-11-26 | Complete Genomics, Inc. | Methods and compositions for long fragment read sequencing |
| EP2227563B1 (fr) * | 2007-12-05 | 2012-06-06 | Complete Genomics, Inc. | Détermination efficace des bases dans les réactions de séquençage |
| EP2565279B1 (fr) | 2007-12-05 | 2014-12-03 | Complete Genomics, Inc. | Détermination efficace des bases dans les réactions de séquençage |
| WO2009094583A1 (fr) * | 2008-01-23 | 2009-07-30 | Complete Genomics, Inc. | Procédés et compositions pour empêcher des écarts dans les réactions d'amplification et de séquençage |
| WO2009097368A2 (fr) * | 2008-01-28 | 2009-08-06 | Complete Genomics, Inc. | Procédés et compositions pour un appel de base efficace dans des réactions de séquençage |
| US9017973B2 (en) | 2008-03-19 | 2015-04-28 | Intelligent Biosystems, Inc. | Methods and compositions for incorporating nucleotides |
| EP4230747A3 (fr) | 2008-03-28 | 2023-11-15 | Pacific Biosciences Of California, Inc. | Compositions et procédés de séquençage d'acide nucléique |
| US8628940B2 (en) | 2008-09-24 | 2014-01-14 | Pacific Biosciences Of California, Inc. | Intermittent detection during analytical reactions |
| WO2009120374A2 (fr) | 2008-03-28 | 2009-10-01 | Pacific Biosciences Of California, Inc. | Procédés et compositions pour la préparation d’échantillon d’acide nucléique |
| CA2723265C (fr) * | 2008-05-02 | 2015-11-24 | Epicentre Technologies Corporation | Marquage selectif d'arn par ligature en 5' |
| US9650668B2 (en) | 2008-09-03 | 2017-05-16 | Nabsys 2.0 Llc | Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels |
| CN102186989B (zh) * | 2008-09-03 | 2021-06-29 | 纳伯塞斯2.0有限责任公司 | 用于流体通道中生物分子和其它分析物的电压感测的纵向移位纳米级电极的使用 |
| US8262879B2 (en) | 2008-09-03 | 2012-09-11 | Nabsys, Inc. | Devices and methods for determining the length of biopolymers and distances between probes bound thereto |
| CA2750054C (fr) | 2008-10-24 | 2018-05-29 | Epicentre Technologies Corporation | Compositions terminales de transposon et procede de modification d'acides nucleiques |
| US9080211B2 (en) | 2008-10-24 | 2015-07-14 | Epicentre Technologies Corporation | Transposon end compositions and methods for modifying nucleic acids |
| KR20100076802A (ko) * | 2008-12-26 | 2010-07-06 | 삼성전자주식회사 | Dna 분자를 포함하는 막이 형성된 마이크로어레이 및 그의 제조 방법 |
| US8455260B2 (en) * | 2009-03-27 | 2013-06-04 | Massachusetts Institute Of Technology | Tagged-fragment map assembly |
| WO2010111605A2 (fr) * | 2009-03-27 | 2010-09-30 | Nabsys, Inc. | La présente invention concerne des dispositifs et des procédés d'analyse de biomolécules et des sondes liées à celles-ci |
| US8246799B2 (en) * | 2009-05-28 | 2012-08-21 | Nabsys, Inc. | Devices and methods for analyzing biomolecules and probes bound thereto |
| CN101570784B (zh) * | 2009-06-03 | 2011-11-23 | 东南大学 | 基于信号组合编码的dna连接测序方法 |
| EP2977455B1 (fr) | 2009-06-15 | 2020-04-15 | Complete Genomics, Inc. | Procédé pour un séquençage à lecture de fragments longs |
| US9524369B2 (en) | 2009-06-15 | 2016-12-20 | Complete Genomics, Inc. | Processing and analysis of complex nucleic acid sequence data |
| KR20110018763A (ko) * | 2009-08-18 | 2011-02-24 | 삼성전자주식회사 | 표적 물질을 기판에 고정하는 방법 및 장치 |
| US10174368B2 (en) * | 2009-09-10 | 2019-01-08 | Centrillion Technology Holdings Corporation | Methods and systems for sequencing long nucleic acids |
| CN102858995B (zh) * | 2009-09-10 | 2016-10-26 | 森特瑞隆技术控股公司 | 靶向测序方法 |
| WO2011050000A2 (fr) * | 2009-10-20 | 2011-04-28 | The Regents Of The University Of California | Nanoparticules d'acide nucléique monomoléculaires |
| US9023769B2 (en) | 2009-11-30 | 2015-05-05 | Complete Genomics, Inc. | cDNA library for nucleic acid sequencing |
| US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
| US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| WO2011127099A1 (fr) | 2010-04-05 | 2011-10-13 | Prognosys Biosciences, Inc. | Tests biologiques à codage spatial |
| US10240194B2 (en) | 2010-05-13 | 2019-03-26 | Gen9, Inc. | Methods for nucleotide sequencing and high fidelity polynucleotide synthesis |
| EP2405017A1 (fr) * | 2010-07-06 | 2012-01-11 | Alacris Theranostics GmbH | Procédé de séquençage d'acide nucléique |
| US8715933B2 (en) | 2010-09-27 | 2014-05-06 | Nabsys, Inc. | Assay methods using nicking endonucleases |
| US8725422B2 (en) | 2010-10-13 | 2014-05-13 | Complete Genomics, Inc. | Methods for estimating genome-wide copy number variations |
| US8859201B2 (en) | 2010-11-16 | 2014-10-14 | Nabsys, Inc. | Methods for sequencing a biomolecule by detecting relative positions of hybridized probes |
| WO2012106385A2 (fr) | 2011-01-31 | 2012-08-09 | Apprise Bio, Inc. | Procédés d'identification de multiples épitopes dans des cellules |
| WO2012109574A2 (fr) | 2011-02-11 | 2012-08-16 | Nabsys, Inc. | Procédés de dosage à l'aide de protéines de liaison à l'adn |
| EP2505665A1 (fr) | 2011-03-31 | 2012-10-03 | Queen Mary And Westfield College, University Of London | Marqueurs du cancer |
| EP2694709B1 (fr) | 2011-04-08 | 2016-09-14 | Prognosys Biosciences, Inc. | Constructions peptidiques et systèmes d'essai |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| EP2754078A4 (fr) * | 2011-04-14 | 2015-12-02 | Complete Genomics Inc | Traitement et analyse de données de séquences d'acides nucléiques complexes |
| AU2012304328B2 (en) | 2011-09-09 | 2017-07-20 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for obtaining a sequence |
| CA2859660C (fr) | 2011-09-23 | 2021-02-09 | Illumina, Inc. | Procedes et compositions de sequencage d'acides nucleiques |
| US10837879B2 (en) | 2011-11-02 | 2020-11-17 | Complete Genomics, Inc. | Treatment for stabilizing nucleic acid arrays |
| US20130261984A1 (en) | 2012-03-30 | 2013-10-03 | Illumina, Inc. | Methods and systems for determining fetal chromosomal abnormalities |
| WO2013166517A1 (fr) | 2012-05-04 | 2013-11-07 | Complete Genomics, Inc. | Procédés de détermination des variations du nombre de copies absolu à l'échelle du génome de tumeurs complexes |
| EP4148142B1 (fr) | 2012-05-21 | 2025-08-13 | The Scripps Research Institute | Procédés de préparation d'échantillons |
| US9977861B2 (en) | 2012-07-18 | 2018-05-22 | Illumina Cambridge Limited | Methods and systems for determining haplotypes and phasing of haplotypes |
| US9951386B2 (en) | 2014-06-26 | 2018-04-24 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10273541B2 (en) | 2012-08-14 | 2019-04-30 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US9701998B2 (en) | 2012-12-14 | 2017-07-11 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10752949B2 (en) | 2012-08-14 | 2020-08-25 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10584381B2 (en) | 2012-08-14 | 2020-03-10 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10221442B2 (en) | 2012-08-14 | 2019-03-05 | 10X Genomics, Inc. | Compositions and methods for sample processing |
| US10323279B2 (en) | 2012-08-14 | 2019-06-18 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US11591637B2 (en) | 2012-08-14 | 2023-02-28 | 10X Genomics, Inc. | Compositions and methods for sample processing |
| AU2013302756C1 (en) | 2012-08-14 | 2018-05-17 | 10X Genomics, Inc. | Microcapsule compositions and methods |
| EP4592400A3 (fr) | 2012-10-17 | 2025-10-29 | 10x Genomics Sweden AB | Procédés et produits pour optimiser la detection localisée ou spatiale de l'expression génique dans un échantillon de tissu |
| US10829816B2 (en) | 2012-11-19 | 2020-11-10 | Apton Biosystems, Inc. | Methods of analyte detection |
| CN102978205B (zh) * | 2012-11-19 | 2014-08-20 | 北京诺禾致源生物信息科技有限公司 | 一种应用于标记开发的高通量测序的接头及其运用方法 |
| CA2894694C (fr) | 2012-12-14 | 2023-04-25 | 10X Genomics, Inc. | Procedes et systemes pour le traitement de polynucleotides |
| US10533221B2 (en) | 2012-12-14 | 2020-01-14 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US9914966B1 (en) | 2012-12-20 | 2018-03-13 | Nabsys 2.0 Llc | Apparatus and methods for analysis of biomolecules using high frequency alternating current excitation |
| US10294516B2 (en) | 2013-01-18 | 2019-05-21 | Nabsys 2.0 Llc | Enhanced probe binding |
| KR20200140929A (ko) | 2013-02-08 | 2020-12-16 | 10엑스 제노믹스, 인크. | 폴리뉴클레오티드 바코드 생성 |
| US9328382B2 (en) | 2013-03-15 | 2016-05-03 | Complete Genomics, Inc. | Multiple tagging of individual long DNA fragments |
| WO2014196863A1 (fr) * | 2013-06-07 | 2014-12-11 | Keygene N.V. | Méthode de séquençage ciblé |
| CA2916662C (fr) | 2013-06-25 | 2022-03-08 | Prognosys Biosciences, Inc. | Procedes et systemes pour determiner des motifs spatiales de cibles biologiques dans un echantillon |
| US10395758B2 (en) | 2013-08-30 | 2019-08-27 | 10X Genomics, Inc. | Sequencing methods |
| US10351899B2 (en) | 2013-09-25 | 2019-07-16 | Bio-ID Diagnostics Inc. | Methods for detecting nucleic acid fragments |
| CN106460032B (zh) | 2013-12-05 | 2019-12-24 | 生捷科技控股公司 | 图案化阵列的制备 |
| US10385335B2 (en) | 2013-12-05 | 2019-08-20 | Centrillion Technology Holdings Corporation | Modified surfaces |
| CN107002117B (zh) | 2013-12-05 | 2021-12-10 | 生捷科技控股公司 | 核酸测序方法 |
| US10767222B2 (en) * | 2013-12-11 | 2020-09-08 | Accuragen Holdings Limited | Compositions and methods for detecting rare sequence variants |
| US11859246B2 (en) | 2013-12-11 | 2024-01-02 | Accuragen Holdings Limited | Methods and compositions for enrichment of amplification products |
| US9824068B2 (en) | 2013-12-16 | 2017-11-21 | 10X Genomics, Inc. | Methods and apparatus for sorting data |
| CN103810404A (zh) * | 2014-01-13 | 2014-05-21 | 哈尔滨工程大学 | 基于贝叶斯的高通量dna测序数据匹配增强方法 |
| US11060139B2 (en) | 2014-03-28 | 2021-07-13 | Centrillion Technology Holdings Corporation | Methods for sequencing nucleic acids |
| BR112016023625A2 (pt) | 2014-04-10 | 2018-06-26 | 10X Genomics, Inc. | dispositivos fluídicos, sistemas e métodos para encapsular e particionar reagentes, e aplicações dos mesmos |
| CA2953469A1 (fr) | 2014-06-26 | 2015-12-30 | 10X Genomics, Inc. | Analyse de sequences d'acides nucleiques |
| KR20170023979A (ko) | 2014-06-26 | 2017-03-06 | 10엑스 제노믹스, 인크. | 핵산 서열 조립을 위한 프로세스 및 시스템 |
| WO2015200893A2 (fr) | 2014-06-26 | 2015-12-30 | 10X Genomics, Inc. | Procédés d'analyse d'acides nucléiques provenant de cellules individuelles ou de populations de cellules |
| US12312640B2 (en) | 2014-06-26 | 2025-05-27 | 10X Genomics, Inc. | Analysis of nucleic acid sequences |
| RU2736728C2 (ru) | 2014-10-17 | 2020-11-19 | Иллумина Кембридж Лимитед | Транспозиция с сохранением сцепления генов |
| EP3207134B1 (fr) * | 2014-10-17 | 2019-07-03 | Illumina Cambridge Limited | Transposition conservant la contiguïté |
| BR112017008877A2 (pt) | 2014-10-29 | 2018-07-03 | 10X Genomics Inc | métodos e composições para sequenciamento de ácido nucleico-alvo |
| US9975122B2 (en) | 2014-11-05 | 2018-05-22 | 10X Genomics, Inc. | Instrument systems for integrated sample processing |
| WO2016081740A1 (fr) * | 2014-11-21 | 2016-05-26 | Nanostring Technologies, Inc. | Séquençage sans enzyme ni amplification |
| JP6769969B2 (ja) | 2015-01-12 | 2020-10-14 | 10エックス ジェノミクス, インコーポレイテッド | 核酸配列決定ライブラリーを作製するためのプロセス及びシステム、並びにこれらを使用して作製したライブラリー |
| WO2016115273A1 (fr) | 2015-01-13 | 2016-07-21 | 10X Genomics, Inc. | Systèmes et procédés de visualisation d'informations de variation structurelle et de phasage |
| EP3253479B1 (fr) | 2015-02-04 | 2022-09-21 | The Regents of The University of California | Séquençage d'acides nucléiques contenus dans des entités individuelles par barcoding |
| WO2016130578A1 (fr) | 2015-02-09 | 2016-08-18 | 10X Genomics, Inc. | Systèmes et procédés pour déterminer la variation structurale et la mise en phase au moyen de données d'appel de variant |
| JP6773687B2 (ja) * | 2015-02-17 | 2020-10-21 | エムジーアイ テック カンパニー リミテッドMGI Tech Co., Ltd. | 制御された鎖置換を用いてのdna配列決定 |
| MX2017010857A (es) | 2015-02-24 | 2017-12-11 | 10X Genomics Inc | Metodos para la cobertura de secuencia de acidos nucleicos seleccionados como diana. |
| EP3262407B1 (fr) | 2015-02-24 | 2023-08-30 | 10X Genomics, Inc. | Procédés et systèmes de traitement de cloisonnement |
| EP3901282B1 (fr) | 2015-04-10 | 2023-06-28 | Spatial Transcriptomics AB | Analyse de plusieurs acides nucléiques spatialement différenciés de spécimens biologiques |
| RU2724998C2 (ru) * | 2015-05-11 | 2020-06-29 | Иллюмина, Инк. | Платформа для обнаружения и анализа терапевтических агентов |
| CN116218970A (zh) * | 2015-11-19 | 2023-06-06 | 赛纳生物科技(北京)有限公司 | 用于获得和校正目标多核苷酸的序列信息的方法 |
| WO2017096322A1 (fr) | 2015-12-03 | 2017-06-08 | Accuragen Holdings Limited | Méthodes et compositions pour former des produits de ligature |
| JP6954899B2 (ja) | 2015-12-04 | 2021-10-27 | 10エックス ゲノミクス,インコーポレイテッド | 核酸の解析のための方法及び組成物 |
| CN107034267B (zh) * | 2016-02-03 | 2021-06-08 | 深圳华大智造科技股份有限公司 | 制备候选测序探针集的方法、装置及其应用 |
| WO2017138984A1 (fr) | 2016-02-11 | 2017-08-17 | 10X Genomics, Inc. | Systèmes, procédés, et milieux destinés à l'assemblage de novo de données de séquence du génome entier |
| US10781481B2 (en) | 2016-04-27 | 2020-09-22 | Bio-Rad Laboratories, Inc. | miRNA transcriptome methods and compositions |
| WO2017197343A2 (fr) | 2016-05-12 | 2017-11-16 | 10X Genomics, Inc. | Filtres microfluidiques sur puce |
| WO2017197338A1 (fr) | 2016-05-13 | 2017-11-16 | 10X Genomics, Inc. | Systèmes microfluidiques et procédés d'utilisation |
| CN109511265B (zh) | 2016-05-16 | 2023-07-14 | 安可济控股有限公司 | 通过链鉴定改进测序的方法 |
| ES2979395T3 (es) * | 2016-05-26 | 2024-09-25 | Becton Dickinson Co | Métodos de ajuste del recuento de etiquetas moleculares |
| US11352667B2 (en) | 2016-06-21 | 2022-06-07 | 10X Genomics, Inc. | Nucleic acid sequencing |
| WO2018026873A1 (fr) * | 2016-08-01 | 2018-02-08 | California Institute Of Technology | Sondage séquentiel de cibles moléculaires sur base de codes-barres pseudo-colorés présentant un mécanisme intégré de correction d'erreurs |
| EP4556575A3 (fr) | 2016-11-21 | 2025-10-08 | Bruker Spatial Biology, Inc. | Procédé de séquençage d'acides nucléiques |
| US10011872B1 (en) | 2016-12-22 | 2018-07-03 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10550429B2 (en) | 2016-12-22 | 2020-02-04 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10815525B2 (en) | 2016-12-22 | 2020-10-27 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| ES3026859T3 (en) | 2017-01-04 | 2025-06-12 | Mgi Tech Co Ltd | Stepwise sequencing by non-labeled reversible terminators or natural nucleotides |
| US12264411B2 (en) | 2017-01-30 | 2025-04-01 | 10X Genomics, Inc. | Methods and systems for analysis |
| EP4029939B1 (fr) | 2017-01-30 | 2023-06-28 | 10X Genomics, Inc. | Procédés et systèmes de codage à barres de cellules individuelles sur la base de gouttelettes |
| JP7305611B2 (ja) | 2017-03-17 | 2023-07-10 | アプトン バイオシステムズ インコーポレイテッド | 配列決定および高分解能画像化の方法 |
| EP3625715A4 (fr) | 2017-05-19 | 2021-03-17 | 10X Genomics, Inc. | Systèmes et procédés d'analyse d'ensembles de données |
| US10400235B2 (en) | 2017-05-26 | 2019-09-03 | 10X Genomics, Inc. | Single cell analysis of transposase accessible chromatin |
| EP3445876B1 (fr) | 2017-05-26 | 2023-07-05 | 10X Genomics, Inc. | Analyse de la chromatine accessible par une transposase d'une cellule unique |
| US11505826B2 (en) | 2017-07-12 | 2022-11-22 | Agilent Technologies, Inc. | Sequencing method for genomic rearrangement detection |
| EP3696275B1 (fr) | 2017-10-11 | 2025-12-24 | MGI Tech Co., Ltd. | Procédé d'amélioration du chargement et de la stabilité d'acide nucléique sur un support solide |
| SG11201913654QA (en) | 2017-11-15 | 2020-01-30 | 10X Genomics Inc | Functionalized gel beads |
| US10829815B2 (en) | 2017-11-17 | 2020-11-10 | 10X Genomics, Inc. | Methods and systems for associating physical and genetic properties of biological particles |
| US11203782B2 (en) | 2018-03-29 | 2021-12-21 | Accuragen Holdings Limited | Compositions and methods comprising asymmetric barcoding |
| CN112262218B (zh) | 2018-04-06 | 2024-11-08 | 10X基因组学有限公司 | 用于单细胞处理中的质量控制的系统和方法 |
| EP4245861B1 (fr) | 2018-05-08 | 2025-02-26 | MGI Tech Co., Ltd. | Co-barcoding d'adn à base de billes à un seul tube pour séquençage, haplotypage et assemblage précis et rentables |
| EP3794146B1 (fr) | 2018-05-14 | 2025-12-10 | Bruker Spatial Biology, Inc. | Méthode d'identifcation d'une séquence nucléotide predeterminée |
| IL271454B2 (en) | 2018-05-17 | 2025-04-01 | Illumina Inc | Rapid single-cell genetic sequencing with low Aggregation bias |
| DK3810774T3 (da) | 2018-06-04 | 2023-12-11 | Illumina Inc | Enkeltcelletransskriptom-biblioteker med højt throughput og fremgangsmåder til fremstilling og anvendelse |
| WO2019241290A1 (fr) | 2018-06-12 | 2019-12-19 | Accuragen Holdings Limited | Méthodes et compositions pour former des produits de ligature |
| US11976275B2 (en) * | 2018-06-15 | 2024-05-07 | Kapa Biosystems, Inc. | Generation of double-stranded DNA templates for single molecule sequencing |
| US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
| JP2022501026A (ja) * | 2018-09-19 | 2022-01-06 | アプトン バイオシステムズ インコーポレイテッド | 高密度に詰め込まれた分析物の層および検出方法 |
| WO2020123316A2 (fr) | 2018-12-10 | 2020-06-18 | 10X Genomics, Inc. | Procédés de détermination d'un emplacement d'un analyte biologique dans un échantillon biologique |
| US12529094B2 (en) | 2018-12-10 | 2026-01-20 | 10X Genomics, Inc. | Imaging system hardware |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| BR112021006234A2 (pt) | 2019-03-01 | 2021-09-28 | Illumina, Inc. | Bibliotecas de células únicas e núcleos únicos de alto rendimento e métodos de preparo e uso |
| WO2020180813A1 (fr) | 2019-03-06 | 2020-09-10 | Qiagen Sciences, Llc | Compositions et procédés pour conception d'adaptateurs et construction de bibliothèque d'acides nucléiques pour séquençage à base de rolonies (réplications en cercles roulants) |
| BR112021006173A2 (pt) | 2019-04-29 | 2021-11-16 | Illumina Inc | Métodos para a identificação e análise de micro-organismos viáveis e/ou proliferativos e para determinação da eficácia de um agente antimicrobiano na modulação do crescimento e da proliferação de micro-organismos em uma amostra |
| US20220220542A1 (en) * | 2019-05-13 | 2022-07-14 | Rapid Genomics Llc | Capture and analysis of target genomic regions |
| WO2020243579A1 (fr) | 2019-05-30 | 2020-12-03 | 10X Genomics, Inc. | Procédés de détection de l'hétérogénéité spatiale d'un échantillon biologique |
| CA3148245A1 (fr) * | 2019-07-22 | 2021-01-28 | Igenomx International Genomics Corporation | Procedes et compositions pour une preparation d'echantillon a haut debit au moyen d'une double indexation double unique |
| WO2021083195A1 (fr) * | 2019-10-28 | 2021-05-06 | Mgi Tech Co., Ltd. | Oligonucléotides lieurs d'adn |
| US12157124B2 (en) | 2019-11-06 | 2024-12-03 | 10X Genomics, Inc. | Imaging system hardware |
| WO2021091611A1 (fr) | 2019-11-08 | 2021-05-14 | 10X Genomics, Inc. | Agents de capture d'analytes marqués spatialement pour le multiplexage d'analytes |
| WO2021092433A2 (fr) | 2019-11-08 | 2021-05-14 | 10X Genomics, Inc. | Amélioration de la spécificité de la liaison d'un analyte |
| JP2023508792A (ja) | 2019-12-19 | 2023-03-06 | イルミナ インコーポレイテッド | ハイスループット単一細胞ライブラリー、並びに製造方法及び使用方法 |
| CN115135984B (zh) | 2019-12-23 | 2025-12-23 | 10X基因组学有限公司 | 可逆固定试剂及其使用方法 |
| ES2982420T3 (es) | 2019-12-23 | 2024-10-16 | 10X Genomics Inc | Métodos para el análisis espacial mediante el uso de la ligazón con plantilla de ARN |
| EP4081656A1 (fr) | 2019-12-23 | 2022-11-02 | 10X Genomics, Inc. | Compositions et méthodes d'utilisation d'échantillons biologiques fixés dans des dosages basés sur des compartiments |
| US12365942B2 (en) | 2020-01-13 | 2025-07-22 | 10X Genomics, Inc. | Methods of decreasing background on a spatial array |
| US12405264B2 (en) | 2020-01-17 | 2025-09-02 | 10X Genomics, Inc. | Electrophoretic system and method for analyte capture |
| US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
| US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
| US20210230681A1 (en) | 2020-01-24 | 2021-07-29 | 10X Genomics, Inc. | Methods for spatial analysis using proximity ligation |
| US11821035B1 (en) | 2020-01-29 | 2023-11-21 | 10X Genomics, Inc. | Compositions and methods of making gene expression libraries |
| US12076701B2 (en) | 2020-01-31 | 2024-09-03 | 10X Genomics, Inc. | Capturing oligonucleotides in spatial transcriptomics |
| US11898205B2 (en) | 2020-02-03 | 2024-02-13 | 10X Genomics, Inc. | Increasing capture efficiency of spatial assays |
| US12110541B2 (en) * | 2020-02-03 | 2024-10-08 | 10X Genomics, Inc. | Methods for preparing high-resolution spatial arrays |
| US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
| WO2021158925A1 (fr) | 2020-02-07 | 2021-08-12 | 10X Genomics, Inc. | Évaluation quantitative et automatisée de la performance de perméabilisation pour la transcriptomique spatiale |
| US11835462B2 (en) | 2020-02-11 | 2023-12-05 | 10X Genomics, Inc. | Methods and compositions for partitioning a biological sample |
| CN115428088A (zh) | 2020-02-13 | 2022-12-02 | 10X基因组学有限公司 | 用于基因表达和dna染色质可及性的联合交互式可视化的系统和方法 |
| US12281357B1 (en) | 2020-02-14 | 2025-04-22 | 10X Genomics, Inc. | In situ spatial barcoding |
| US12399123B1 (en) | 2020-02-14 | 2025-08-26 | 10X Genomics, Inc. | Spatial targeting of analytes |
| US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
| US11926863B1 (en) | 2020-02-27 | 2024-03-12 | 10X Genomics, Inc. | Solid state single cell method for analyzing fixed biological cells |
| US11768175B1 (en) | 2020-03-04 | 2023-09-26 | 10X Genomics, Inc. | Electrophoretic methods for spatial analysis |
| EP4139485B1 (fr) | 2020-04-22 | 2023-09-06 | 10X Genomics, Inc. | Procédés d'analyse spatiale utilisant un appauvrissement d'arn ciblée |
| US12416603B2 (en) | 2020-05-19 | 2025-09-16 | 10X Genomics, Inc. | Electrophoresis cassettes and instrumentation |
| EP4153776B1 (fr) | 2020-05-22 | 2025-03-05 | 10X Genomics, Inc. | Analyse spatiale pour détecter des variants de séquence |
| EP4414459B1 (fr) | 2020-05-22 | 2025-09-03 | 10X Genomics, Inc. | Mesure spatio-temporelle simultanée de l'expression génique et de l'activité cellulaire |
| WO2021242834A1 (fr) | 2020-05-26 | 2021-12-02 | 10X Genomics, Inc. | Procédé de réinitialisation d'un réseau |
| US12265079B1 (en) | 2020-06-02 | 2025-04-01 | 10X Genomics, Inc. | Systems and methods for detecting analytes from captured single biological particles |
| AU2021283174A1 (en) | 2020-06-02 | 2023-01-05 | 10X Genomics, Inc. | Nucleic acid library methods |
| EP4600376A3 (fr) | 2020-06-02 | 2025-10-22 | 10X Genomics, Inc. | Transcriptome spatial pour récepteurs d'antigènes |
| US12031177B1 (en) | 2020-06-04 | 2024-07-09 | 10X Genomics, Inc. | Methods of enhancing spatial resolution of transcripts |
| EP4421186B1 (fr) | 2020-06-08 | 2025-08-13 | 10X Genomics, Inc. | Procédés de détermination d'une marge chirurgicale et procédés d'utilisation de ceux-ci |
| WO2021252617A1 (fr) | 2020-06-09 | 2021-12-16 | Illumina, Inc. | Procédés pour augmenter le rendement de bibliothèques de séquençage |
| EP4165207B1 (fr) | 2020-06-10 | 2024-09-25 | 10X Genomics, Inc. | Methode pour determiner la position d'un analyte dans un echantillon biologique |
| WO2021252747A1 (fr) | 2020-06-10 | 2021-12-16 | 1Ox Genomics, Inc. | Procédés de distribution de fluide |
| US12435363B1 (en) | 2020-06-10 | 2025-10-07 | 10X Genomics, Inc. | Materials and methods for spatial transcriptomics |
| ES2994976T3 (en) | 2020-06-25 | 2025-02-05 | 10X Genomics Inc | Spatial analysis of dna methylation |
| US11761038B1 (en) | 2020-07-06 | 2023-09-19 | 10X Genomics, Inc. | Methods for identifying a location of an RNA in a biological sample |
| US11981960B1 (en) | 2020-07-06 | 2024-05-14 | 10X Genomics, Inc. | Spatial analysis utilizing degradable hydrogels |
| US12209280B1 (en) | 2020-07-06 | 2025-01-28 | 10X Genomics, Inc. | Methods of identifying abundance and location of an analyte in a biological sample using second strand synthesis |
| US12553898B1 (en) | 2020-08-10 | 2026-02-17 | 10X Genomics, Inc. | Fluorescent hybridization of antibody-oligonucleotide for multiplexing and signal amplification |
| US11981958B1 (en) | 2020-08-20 | 2024-05-14 | 10X Genomics, Inc. | Methods for spatial analysis using DNA capture |
| WO2022061150A2 (fr) | 2020-09-18 | 2022-03-24 | 10X Geonomics, Inc. | Appareil de manipulation d'échantillons et procédés d'enregistrement d'images |
| US11926822B1 (en) | 2020-09-23 | 2024-03-12 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
| US20230366023A1 (en) | 2020-10-09 | 2023-11-16 | Bgi Shenzhen Co., Ltd. | Methods and compositions for bioluminescence-based sequencing |
| US11827935B1 (en) | 2020-11-19 | 2023-11-28 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification and detection probes |
| EP4729631A2 (fr) | 2020-12-21 | 2026-04-22 | 10X Genomics, Inc. | Procédés, compositions et systèmes de capture de sondes et/ou de codes à barres |
| EP4421491A3 (fr) | 2021-02-19 | 2024-11-27 | 10X Genomics, Inc. | Procédé d'utilisation d'un dispositif de support d'analyse modulaire |
| AU2022238446A1 (en) | 2021-03-18 | 2023-09-07 | 10X Genomics, Inc. | Multiplex capture of gene and protein expression from a biological sample |
| EP4305196B1 (fr) | 2021-04-14 | 2025-04-02 | 10X Genomics, Inc. | Procédés de mesure d'une mauvaise localisation d'un analyte |
| US12176070B2 (en) * | 2021-04-19 | 2024-12-24 | University Of Utah Research Foundation | Systems and methods for facilitating rapid genome sequence analysis |
| EP4320271B1 (fr) | 2021-05-06 | 2025-03-19 | 10X Genomics, Inc. | Procédés pour augmenter la résolution d'une analyse spatiale |
| US11667968B2 (en) * | 2021-05-27 | 2023-06-06 | New England Biolabs, Inc. | Fragmentation of DNA |
| WO2022256503A1 (fr) | 2021-06-03 | 2022-12-08 | 10X Genomics, Inc. | Procédés, compositions, kits et systèmes pour améliorer la capture d'analytes pour une analyse spatiale |
| IL310293A (en) * | 2021-07-22 | 2024-03-01 | Mgi Tech Co Ltd | STLFR cut-tie |
| US12553805B2 (en) | 2021-08-02 | 2026-02-17 | 10X Genomics, Inc. | Methods of preserving a biological sample |
| WO2023034489A1 (fr) | 2021-09-01 | 2023-03-09 | 10X Genomics, Inc. | Procédés, compositions et kits pour bloquer une sonde de capture sur un réseau spatial |
| WO2023086880A1 (fr) | 2021-11-10 | 2023-05-19 | 10X Genomics, Inc. | Procédés, compositions et kits pour déterminer l'emplacement d'un analyte dans un échantillon biologique |
| WO2023102118A2 (fr) | 2021-12-01 | 2023-06-08 | 10X Genomics, Inc. | Procédés, compositions et systèmes pour la détection améliorée d'analytes in situ et analyse spatiale |
| WO2023122033A1 (fr) | 2021-12-20 | 2023-06-29 | 10X Genomics, Inc. | Auto-test pour dispositif d'imagerie |
| AU2023248405A1 (en) | 2022-04-07 | 2024-01-04 | Illumina, Inc. | Altered cytidine deaminases and methods of use |
| EP4594482A1 (fr) | 2022-09-30 | 2025-08-06 | Illumina, Inc. | Cytidine désaminases et procédés d'utilisation dans la cartographie de nucléotides cytosine modifiés |
| WO2024073043A1 (fr) | 2022-09-30 | 2024-04-04 | Illumina, Inc. | Procédés d'utilisation de protéines de liaison cpg dans la cartographie de nucléotides cytosine modifiés |
| WO2024069581A1 (fr) | 2022-09-30 | 2024-04-04 | Illumina Singapore Pte. Ltd. | Complexes hélicase-cytidine désaminase et procédés d'utilisation |
| CN115409174B (zh) * | 2022-11-01 | 2023-03-31 | 之江实验室 | 一种基于dram存内计算的碱基序列过滤方法与装置 |
| EP4482979B1 (fr) | 2022-11-09 | 2025-10-01 | 10X Genomics, Inc. | Procédés, compositions et kits pour déterminer l'emplacement de plusieurs analytes dans un échantillon biologique |
| WO2025072783A1 (fr) | 2023-09-28 | 2025-04-03 | Illumina, Inc. | Cytidine désaminases modifiées et méthodes d'utilisation |
| WO2025081064A2 (fr) | 2023-10-11 | 2025-04-17 | Illumina, Inc. | Désaminase thermophile et procédés d'identification de cytosine modifiée |
| WO2025137222A1 (fr) | 2023-12-19 | 2025-06-26 | Illumina, Inc. | Dosage de détection de méthylation |
| WO2025264831A1 (fr) | 2024-06-18 | 2025-12-26 | Illumina, Inc. | Procédés pour augmenter la qualité de séquençage de régions riches en gc |
| WO2025264836A1 (fr) | 2024-06-18 | 2025-12-26 | Illumina, Inc. | Procédés pour augmenter la qualité de séquençage de régions riches en gc |
| WO2026006774A1 (fr) | 2024-06-28 | 2026-01-02 | Illumina, Inc. | Cytidine désaminases modifiées et procédés d'utilisation |
| WO2026006314A1 (fr) | 2024-06-28 | 2026-01-02 | Illumina, Inc. | Marquage de régions cibles avant le séquençage de nucléotides |
| CN119832990B (zh) * | 2024-12-19 | 2025-09-16 | 公安部第一研究所 | 一种利用slsqp分析二混dna的混合比例方法 |
| CN120442620B (zh) * | 2025-07-11 | 2025-10-31 | 良渚实验室 | 用于蛋白检测体系的寡核苷酸阻断剂及降低基于邻位反应的超灵敏蛋白检测体系背景的方法 |
Family Cites Families (168)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US503645A (en) * | 1893-08-22 | brooks | ||
| US2002671A (en) * | 1935-02-21 | 1935-05-28 | Buffalo Bolt Company | Screw and trunnion nut device and method of making it |
| US4318846A (en) | 1979-09-07 | 1982-03-09 | Syva Company | Novel ether substituted fluorescein polyamino acid compounds as fluorescers and quenchers |
| US4469863A (en) | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
| US4994373A (en) * | 1983-01-27 | 1991-02-19 | Enzo Biochem, Inc. | Method and structures employing chemically-labelled polynucleotide probes |
| US4605735A (en) | 1983-02-14 | 1986-08-12 | Wakunaga Seiyaku Kabushiki Kaisha | Oligonucleotide derivatives |
| US4719179A (en) * | 1984-11-30 | 1988-01-12 | Pharmacia P-L Biochemicals, Inc. | Six base oligonucleotide linkers and methods for their use |
| US4883750A (en) | 1984-12-13 | 1989-11-28 | Applied Biosystems, Inc. | Detection of specific sequences in nucleic acids |
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| US5235033A (en) | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
| US4757141A (en) | 1985-08-26 | 1988-07-12 | Applied Biosystems, Incorporated | Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors, and useful conjugates thereof |
| US5091519A (en) | 1986-05-01 | 1992-02-25 | Amoco Corporation | Nucleotide compositions with linking groups |
| US5151507A (en) | 1986-07-02 | 1992-09-29 | E. I. Du Pont De Nemours And Company | Alkynylamino-nucleotides |
| US5202231A (en) * | 1987-04-01 | 1993-04-13 | Drmanac Radoje T | Method of sequencing of genomes by hybridization of oligonucleotide probes |
| US5525464A (en) * | 1987-04-01 | 1996-06-11 | Hyseq, Inc. | Method of sequencing by hybridization of oligonucleotide probes |
| US6270961B1 (en) * | 1987-04-01 | 2001-08-07 | Hyseq, Inc. | Methods and apparatus for DNA sequencing and DNA identification |
| US5124246A (en) * | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| US4886741A (en) | 1987-12-09 | 1989-12-12 | Microprobe Corporation | Use of volume exclusion agents for the enhancement of in situ hybridization |
| US5354657A (en) | 1988-01-12 | 1994-10-11 | Boehringer Mannheim Gmbh | Process for the highly specific detection of nucleic acids in solid |
| DE3813278A1 (de) | 1988-01-12 | 1989-07-20 | Boehringer Mannheim Gmbh | Verfahren zum nachweis von nukleinsaeuren |
| US5216141A (en) | 1988-06-06 | 1993-06-01 | Benner Steven A | Oligonucleotide analogs containing sulfur linkages |
| US5066580A (en) | 1988-08-31 | 1991-11-19 | Becton Dickinson And Company | Xanthene dyes that emit to the red of fluorescein |
| DE3836656A1 (de) * | 1988-10-27 | 1990-05-03 | Boehringer Mannheim Gmbh | Neue digoxigenin-derivate und ihre verwendung |
| US5091302A (en) * | 1989-04-27 | 1992-02-25 | The Blood Center Of Southeastern Wisconsin, Inc. | Polymorphism of human platelet membrane glycoprotein iiia and diagnostic and therapeutic applications thereof |
| US6416952B1 (en) * | 1989-06-07 | 2002-07-09 | Affymetrix, Inc. | Photolithographic and other means for manufacturing arrays |
| US5800992A (en) * | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US5744101A (en) * | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US6346413B1 (en) * | 1989-06-07 | 2002-02-12 | Affymetrix, Inc. | Polymer arrays |
| US5366860A (en) | 1989-09-29 | 1994-11-22 | Applied Biosystems, Inc. | Spectrally resolvable rhodamine dyes for nucleic acid sequence determination |
| US5188934A (en) | 1989-11-14 | 1993-02-23 | Applied Biosystems, Inc. | 4,7-dichlorofluorescein dyes as molecular probes |
| US5427930A (en) * | 1990-01-26 | 1995-06-27 | Abbott Laboratories | Amplification of target nucleic acids using gap filling ligase chain reaction |
| CA2036946C (fr) | 1990-04-06 | 2001-10-16 | Kenneth V. Deugau | Molecules de liaison pour indexation |
| US5198337A (en) | 1990-04-13 | 1993-03-30 | State Of Oregon | Assay for gene deletion of GST-1 in human samples based on the polymerase chain reaction |
| US5073562A (en) | 1990-05-10 | 1991-12-17 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof |
| US5602240A (en) | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
| US5386023A (en) | 1990-07-27 | 1995-01-31 | Isis Pharmaceuticals | Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling |
| US5426180A (en) | 1991-03-27 | 1995-06-20 | Research Corporation Technologies, Inc. | Methods of making single-stranded circular oligonucleotides |
| US6589726B1 (en) * | 1991-09-04 | 2003-07-08 | Metrigen, Inc. | Method and apparatus for in situ synthesis on a solid support |
| US5474796A (en) * | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
| AU672760B2 (en) | 1991-09-24 | 1996-10-17 | Keygene N.V. | Selective restriction fragment amplification: a general method for DNA fingerprinting |
| US5632957A (en) * | 1993-11-01 | 1997-05-27 | Nanogen | Molecular biological diagnostic systems including electrodes |
| US5644048A (en) | 1992-01-10 | 1997-07-01 | Isis Pharmaceuticals, Inc. | Process for preparing phosphorothioate oligonucleotides |
| US5403708A (en) * | 1992-07-06 | 1995-04-04 | Brennan; Thomas M. | Methods and compositions for determining the sequence of nucleic acids |
| GB9214873D0 (en) | 1992-07-13 | 1992-08-26 | Medical Res Council | Process for categorising nucleotide sequence populations |
| US6261808B1 (en) * | 1992-08-04 | 2001-07-17 | Replicon, Inc. | Amplification of nucleic acid molecules via circular replicons |
| WO1994003624A1 (fr) | 1992-08-04 | 1994-02-17 | Auerbach Jeffrey I | Procedes d'amplification isothermique de molecules d'acide nucleique |
| US5834202A (en) * | 1992-08-04 | 1998-11-10 | Replicon, Inc. | Methods for the isothermal amplification of nucleic acid molecules |
| US6096880A (en) * | 1993-04-15 | 2000-08-01 | University Of Rochester | Circular DNA vectors for synthesis of RNA and DNA |
| US6077668A (en) * | 1993-04-15 | 2000-06-20 | University Of Rochester | Highly sensitive multimeric nucleic acid probes |
| US5714320A (en) * | 1993-04-15 | 1998-02-03 | University Of Rochester | Rolling circle synthesis of oligonucleotides and amplification of select randomized circular oligonucleotides |
| US5473060A (en) | 1993-07-02 | 1995-12-05 | Lynx Therapeutics, Inc. | Oligonucleotide clamps having diagnostic applications |
| WO1995001365A1 (fr) | 1993-07-02 | 1995-01-12 | Lynx Therapeutics, Inc. | Synthese d'acides nucleiques ramifies |
| US6401267B1 (en) | 1993-09-27 | 2002-06-11 | Radoje Drmanac | Methods and compositions for efficient nucleic acid sequencing |
| US5654419A (en) | 1994-02-01 | 1997-08-05 | The Regents Of The University Of California | Fluorescent labels and their use in separations |
| SE9400522D0 (sv) | 1994-02-16 | 1994-02-16 | Ulf Landegren | Method and reagent for detecting specific nucleotide sequences |
| US5637684A (en) | 1994-02-23 | 1997-06-10 | Isis Pharmaceuticals, Inc. | Phosphoramidate and phosphorothioamidate oligomeric compounds |
| US5641658A (en) * | 1994-08-03 | 1997-06-24 | Mosaic Technologies, Inc. | Method for performing amplification of nucleic acid with two primers bound to a single solid support |
| US5710000A (en) * | 1994-09-16 | 1998-01-20 | Affymetrix, Inc. | Capturing sequences adjacent to Type-IIs restriction sites for genomic library mapping |
| US6013445A (en) | 1996-06-06 | 2000-01-11 | Lynx Therapeutics, Inc. | Massively parallel signature sequencing by ligation of encoded adaptors |
| US6654505B2 (en) | 1994-10-13 | 2003-11-25 | Lynx Therapeutics, Inc. | System and apparatus for sequential processing of analytes |
| FR2726286B1 (fr) * | 1994-10-28 | 1997-01-17 | Genset Sa | Procede d'amplification d'acides nucleiques en phase solide et trousse de reactifs utile pour la mise en oeuvre de ce procede |
| US5866337A (en) * | 1995-03-24 | 1999-02-02 | The Trustees Of Columbia University In The City Of New York | Method to detect mutations in a nucleic acid using a hybridization-ligation procedure |
| US5750341A (en) * | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
| US5648245A (en) * | 1995-05-09 | 1997-07-15 | Carnegie Institution Of Washington | Method for constructing an oligonucleotide concatamer library by rolling circle replication |
| KR19990014709A (ko) | 1995-05-12 | 1999-02-25 | 한스루돌프하우스 | 센서 플랫폼 및 감쇠 여기된 발광을 이용한 복수 분석물의병렬 검출 방법 |
| US5774305A (en) | 1995-06-07 | 1998-06-30 | Seagate Technology, Inc. | Head gimbal assembly to reduce slider distortion due to thermal stress |
| DK0862656T3 (da) | 1995-11-21 | 2001-04-09 | Univ Yale | Unimolekylær segmentamplifikation og -detektering |
| US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
| ATE238434T1 (de) | 1995-12-05 | 2003-05-15 | Jorn Erland Koch | Eine in kaskaden verlaufende vervielfältigungsreaktion von nukleinsäuren |
| US5847162A (en) | 1996-06-27 | 1998-12-08 | The Perkin Elmer Corporation | 4, 7-Dichlororhodamine dyes |
| US5800996A (en) | 1996-05-03 | 1998-09-01 | The Perkin Elmer Corporation | Energy transfer dyes with enchanced fluorescence |
| US5851804A (en) | 1996-05-06 | 1998-12-22 | Apollon, Inc. | Chimeric kanamycin resistance gene |
| US5869245A (en) * | 1996-06-05 | 1999-02-09 | Fox Chase Cancer Center | Mismatch endonuclease and its use in identifying mutations in targeted polynucleotide strands |
| JP3363735B2 (ja) * | 1996-06-26 | 2003-01-08 | 松下電器産業株式会社 | X線画像装置 |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| US5916750A (en) * | 1997-01-08 | 1999-06-29 | Biogenex Laboratories | Multifunctional linking reagents for synthesis of branched oligomers |
| US6297006B1 (en) | 1997-01-16 | 2001-10-02 | Hyseq, Inc. | Methods for sequencing repetitive sequences and for determining the order of sequence subfragments |
| US6309824B1 (en) | 1997-01-16 | 2001-10-30 | Hyseq, Inc. | Methods for analyzing a target nucleic acid using immobilized heterogeneous mixtures of oligonucleotide probes |
| US5994068A (en) | 1997-03-11 | 1999-11-30 | Wisconsin Alumni Research Foundation | Nucleic acid indexing |
| JP2001517948A (ja) * | 1997-04-01 | 2001-10-09 | グラクソ、グループ、リミテッド | 核酸配列決定法 |
| US5888737A (en) * | 1997-04-15 | 1999-03-30 | Lynx Therapeutics, Inc. | Adaptor-based sequence analysis |
| US20040229221A1 (en) | 1997-05-08 | 2004-11-18 | Trustees Of Columbia University In The City Of New York | Method to detect mutations in a nucleic acid using a hybridization-ligation procedure |
| ES2230701T3 (es) | 1997-07-07 | 2005-05-01 | Medical Research Council | Procedimiento de seleccion in vitro. |
| US6124120A (en) * | 1997-10-08 | 2000-09-26 | Yale University | Multiple displacement amplification |
| JP2001519538A (ja) * | 1997-10-10 | 2001-10-23 | プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ | 核酸アレイのレプリカ増幅 |
| US6322901B1 (en) | 1997-11-13 | 2001-11-27 | Massachusetts Institute Of Technology | Highly luminescent color-selective nano-crystalline materials |
| US5990479A (en) | 1997-11-25 | 1999-11-23 | Regents Of The University Of California | Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes |
| US6207392B1 (en) | 1997-11-25 | 2001-03-27 | The Regents Of The University Of California | Semiconductor nanocrystal probes for biological applications and process for making and using such probes |
| US6136537A (en) | 1998-02-23 | 2000-10-24 | Macevicz; Stephen C. | Gene expression analysis |
| AU3601599A (en) * | 1998-03-25 | 1999-10-18 | Ulf Landegren | Rolling circle replication of padlock probes |
| US6004755A (en) | 1998-04-07 | 1999-12-21 | Incyte Pharmaceuticals, Inc. | Quantitative microarray hybridizaton assays |
| US6284497B1 (en) | 1998-04-09 | 2001-09-04 | Trustees Of Boston University | Nucleic acid arrays and methods of synthesis |
| US6255469B1 (en) * | 1998-05-06 | 2001-07-03 | New York University | Periodic two and three dimensional nucleic acid structures |
| WO2000004193A1 (fr) | 1998-07-20 | 2000-01-27 | Yale University | Procede pour detecter des acides nucleiques au moyen de ligature a mediation par cibles d'amorces bipartites |
| WO2000006770A1 (fr) * | 1998-07-30 | 2000-02-10 | Solexa Ltd. | Biomolecules en rangees et leur utilisation dans une procedure de sequençage |
| US6787308B2 (en) | 1998-07-30 | 2004-09-07 | Solexa Ltd. | Arrayed biomolecules and their use in sequencing |
| US6232067B1 (en) * | 1998-08-17 | 2001-05-15 | The Perkin-Elmer Corporation | Adapter directed expression analysis |
| WO2000014282A1 (fr) | 1998-09-04 | 2000-03-16 | Lynx Therapeutics, Inc. | Procede de depistage de polymorphisme genique |
| JP2002525049A (ja) | 1998-09-15 | 2002-08-13 | イェール ユニバーシティ | ローリングサークル増幅を用いる分子クローニング |
| US6251303B1 (en) | 1998-09-18 | 2001-06-26 | Massachusetts Institute Of Technology | Water-soluble fluorescent nanocrystals |
| US6326144B1 (en) | 1998-09-18 | 2001-12-04 | Massachusetts Institute Of Technology | Biological applications of quantum dots |
| US6235502B1 (en) * | 1998-09-18 | 2001-05-22 | Molecular Staging Inc. | Methods for selectively isolating DNA using rolling circle amplification |
| US6426513B1 (en) | 1998-09-18 | 2002-07-30 | Massachusetts Institute Of Technology | Water-soluble thiol-capped nanocrystals |
| US6864052B1 (en) | 1999-01-06 | 2005-03-08 | Callida Genomics, Inc. | Enhanced sequencing by hybridization using pools of probes |
| US6534293B1 (en) * | 1999-01-06 | 2003-03-18 | Cornell Research Foundation, Inc. | Accelerating identification of single nucleotide polymorphisms and alignment of clones in genomic sequencing |
| GB9901475D0 (en) | 1999-01-22 | 1999-03-17 | Pyrosequencing Ab | A method of DNA sequencing |
| US6514768B1 (en) | 1999-01-29 | 2003-02-04 | Surmodics, Inc. | Replicable probe array |
| AU4701200A (en) | 1999-05-07 | 2000-11-21 | Quantum Dot Corporation | A method of detecting an analyte using semiconductor nanocrystals |
| EP1190100B1 (fr) | 1999-05-20 | 2012-07-25 | Illumina, Inc. | Decodage combinatoire de jeux d'acides nucleiques aleatoires |
| US6573369B2 (en) * | 1999-05-21 | 2003-06-03 | Bioforce Nanosciences, Inc. | Method and apparatus for solid state molecular analysis |
| US6818395B1 (en) | 1999-06-28 | 2004-11-16 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences |
| US6472156B1 (en) | 1999-08-30 | 2002-10-29 | The University Of Utah | Homogeneous multiplex hybridization analysis by color and Tm |
| US7244559B2 (en) * | 1999-09-16 | 2007-07-17 | 454 Life Sciences Corporation | Method of sequencing a nucleic acid |
| US6274320B1 (en) * | 1999-09-16 | 2001-08-14 | Curagen Corporation | Method of sequencing a nucleic acid |
| US7211390B2 (en) * | 1999-09-16 | 2007-05-01 | 454 Life Sciences Corporation | Method of sequencing a nucleic acid |
| AU7537200A (en) | 1999-09-29 | 2001-04-30 | Solexa Ltd. | Polynucleotide sequencing |
| US6297016B1 (en) | 1999-10-08 | 2001-10-02 | Applera Corporation | Template-dependent ligation with PNA-DNA chimeric probes |
| WO2001040516A2 (fr) * | 1999-12-02 | 2001-06-07 | Molecular Staging Inc. | Generation d'adn circulaire a un seul brin a partir de segments lineaires de renaturation automatique |
| WO2001048242A2 (fr) | 1999-12-29 | 2001-07-05 | Mergen Ltd. | Procedes d'amplification et de detection de plusieurs polynucleotides sur un support en phase solide |
| GB0002389D0 (en) * | 2000-02-02 | 2000-03-22 | Solexa Ltd | Molecular arrays |
| US6221603B1 (en) * | 2000-02-04 | 2001-04-24 | Molecular Dynamics, Inc. | Rolling circle amplification assay for nucleic acid analysis |
| US6913884B2 (en) * | 2001-08-16 | 2005-07-05 | Illumina, Inc. | Compositions and methods for repetitive use of genomic DNA |
| DK1259643T3 (da) * | 2000-02-07 | 2009-02-23 | Illumina Inc | Fremgangsmåde til detektion af nukleinsyre ved anvendelse af universel priming |
| WO2001057268A2 (fr) | 2000-02-07 | 2001-08-09 | Illumina, Inc. | Detection d'acides nucleiques et procedes utilisant l'amorçage universel |
| WO2001064831A1 (fr) * | 2000-02-29 | 2001-09-07 | The Board Of Trustees Of The Leland Stanford Junior University | Substrat de microreseaux a photodetecteur integre et ses procedes d'utilisation |
| US6413722B1 (en) * | 2000-03-22 | 2002-07-02 | Incyte Genomics, Inc. | Polymer coated surfaces for microarray applications |
| JP2002085097A (ja) * | 2000-09-12 | 2002-03-26 | Hitachi Ltd | Dna塩基配列決定法 |
| US6649138B2 (en) | 2000-10-13 | 2003-11-18 | Quantum Dot Corporation | Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media |
| US6576291B2 (en) | 2000-12-08 | 2003-06-10 | Massachusetts Institute Of Technology | Preparation of nanocrystallites |
| US6783943B2 (en) | 2000-12-20 | 2004-08-31 | The Regents Of The University Of California | Rolling circle amplification detection of RNA and DNA |
| EP2465943A3 (fr) | 2001-03-16 | 2012-10-03 | Kalim Mir | Affichage de polymère linéaire |
| JP4567436B2 (ja) | 2001-07-20 | 2010-10-20 | ライフ テクノロジーズ コーポレーション | 発光ナノ粒子およびそれらの調製方法 |
| US7297778B2 (en) | 2001-07-25 | 2007-11-20 | Affymetrix, Inc. | Complexity management of genomic DNA |
| GB2382137A (en) | 2001-11-20 | 2003-05-21 | Mats Gullberg | Nucleic acid enrichment |
| US7011945B2 (en) * | 2001-12-21 | 2006-03-14 | Eastman Kodak Company | Random array of micro-spheres for the analysis of nucleic acids |
| US20040002090A1 (en) * | 2002-03-05 | 2004-01-01 | Pascal Mayer | Methods for detecting genome-wide sequence variations associated with a phenotype |
| DE10224339A1 (de) | 2002-05-29 | 2003-12-11 | Axaron Bioscience Ag | Verfahren zur hochparallelen Nukleinsäuresequenzierung |
| AUPS298102A0 (en) | 2002-06-13 | 2002-07-04 | Nucleics Pty Ltd | Method for performing chemical reactions |
| US20050019776A1 (en) | 2002-06-28 | 2005-01-27 | Callow Matthew James | Universal selective genome amplification and universal genotyping system |
| EP1556506A1 (fr) | 2002-09-19 | 2005-07-27 | The Chancellor, Masters And Scholars Of The University Of Oxford | Reseaux moleculaires et detection de molecule unique |
| US7459273B2 (en) | 2002-10-04 | 2008-12-02 | Affymetrix, Inc. | Methods for genotyping selected polymorphism |
| JP4395133B2 (ja) | 2002-12-20 | 2010-01-06 | カリパー・ライフ・サイエンシズ・インク. | Dnaの単一分子増幅および検出 |
| US6977153B2 (en) | 2002-12-31 | 2005-12-20 | Qiagen Gmbh | Rolling circle amplification of RNA |
| CA2513899C (fr) | 2003-01-29 | 2013-03-26 | 454 Corporation | Procede d'amplification et de sequencage d'acides nucleiques |
| CN103396933B (zh) * | 2003-02-26 | 2016-04-20 | 凯利达基因组股份有限公司 | 通过杂交进行的随机阵列dna分析 |
| FR2852605B1 (fr) * | 2003-03-18 | 2012-11-30 | Commissariat Energie Atomique | Procede de preparation de fragments d'adn et ses applications |
| US8222005B2 (en) * | 2003-09-17 | 2012-07-17 | Agency For Science, Technology And Research | Method for gene identification signature (GIS) analysis |
| EP1685380A2 (fr) | 2003-09-18 | 2006-08-02 | Parallele Bioscience, Inc. | Systeme et procedes pour renforcer les rapports signal/bruit dans les mesures par microreseaux |
| US20060024681A1 (en) * | 2003-10-31 | 2006-02-02 | Agencourt Bioscience Corporation | Methods for producing a paired tag from a nucleic acid sequence and methods of use thereof |
| US7927797B2 (en) | 2004-01-28 | 2011-04-19 | 454 Life Sciences Corporation | Nucleic acid amplification with continuous flow emulsion |
| AU2005216549A1 (en) | 2004-02-27 | 2005-09-09 | President And Fellows Of Harvard College | Polony fluorescent in situ sequencing beads |
| US20050214840A1 (en) | 2004-03-23 | 2005-09-29 | Xiangning Chen | Restriction enzyme mediated method of multiplex genotyping |
| US20060002471A1 (en) | 2004-06-30 | 2006-01-05 | Lippincott Louis A | Motion estimation unit |
| US20060024711A1 (en) * | 2004-07-02 | 2006-02-02 | Helicos Biosciences Corporation | Methods for nucleic acid amplification and sequence determination |
| US7276720B2 (en) | 2004-07-19 | 2007-10-02 | Helicos Biosciences Corporation | Apparatus and methods for analyzing samples |
| US20060012793A1 (en) * | 2004-07-19 | 2006-01-19 | Helicos Biosciences Corporation | Apparatus and methods for analyzing samples |
| GB0422551D0 (en) * | 2004-10-11 | 2004-11-10 | Univ Liverpool | Labelling and sequencing of nucleic acids |
| EP1879906A4 (fr) | 2005-01-05 | 2009-07-22 | Advanced Genetic Analysis Corp | Terminateurs nucleotidiques reversibles et leurs utilisations |
| EP3257949A1 (fr) * | 2005-06-15 | 2017-12-20 | Complete Genomics Inc. | Analyse d'acide nucléique par des mélanges aléatoires de fragments non chevauchants |
| US7960104B2 (en) * | 2005-10-07 | 2011-06-14 | Callida Genomics, Inc. | Self-assembled single molecule arrays and uses thereof |
| CA2624896C (fr) * | 2005-10-07 | 2017-11-07 | Callida Genomics, Inc. | Biopuces a molecules simples autoassemblees et utilisations |
| WO2007087310A2 (fr) * | 2006-01-23 | 2007-08-02 | Population Genetics Technologies Ltd. | Analyses d'acides nucléiques au moyen de marques de séquences |
| WO2007092538A2 (fr) * | 2006-02-07 | 2007-08-16 | President And Fellows Of Harvard College | Procédés de confection de sondes nucléotidiques pour séquençage et synthèse |
| SG170028A1 (en) | 2006-02-24 | 2011-04-29 | Callida Genomics Inc | High throughput genome sequencing on dna arrays |
| US7910354B2 (en) | 2006-10-27 | 2011-03-22 | Complete Genomics, Inc. | Efficient arrays of amplified polynucleotides |
| US7897344B2 (en) * | 2007-11-06 | 2011-03-01 | Complete Genomics, Inc. | Methods and oligonucleotide designs for insertion of multiple adaptors into library constructs |
| WO2009061840A1 (fr) | 2007-11-05 | 2009-05-14 | Complete Genomics, Inc. | Procédés et conceptions d'oligonucléotide pour une insertion d'adaptateurs multiples en utilisant une méthylation sélective |
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- 2007-02-26 EP EP07757499A patent/EP1994180A4/fr not_active Withdrawn
- 2007-02-26 CA CA002643700A patent/CA2643700A1/fr not_active Abandoned
- 2007-02-26 EP EP12158929A patent/EP2495337A1/fr not_active Withdrawn
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- 2007-02-26 JP JP2008556583A patent/JP5180845B2/ja active Active
- 2007-02-26 WO PCT/US2007/062825 patent/WO2007133831A2/fr not_active Ceased
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11414702B2 (en) | 2005-06-15 | 2022-08-16 | Complete Genomics, Inc. | Nucleic acid analysis by random mixtures of non-overlapping fragments |
Also Published As
| Publication number | Publication date |
|---|---|
| US8722326B2 (en) | 2014-05-13 |
| CN101432439B (zh) | 2013-07-24 |
| EP1994180A4 (fr) | 2009-11-25 |
| CA2643700A1 (fr) | 2007-11-22 |
| US20090005252A1 (en) | 2009-01-01 |
| AU2007249635A1 (en) | 2007-11-22 |
| WO2007133831A3 (fr) | 2008-02-07 |
| IL193599A0 (en) | 2009-05-04 |
| IL238895B (en) | 2018-05-31 |
| EP2495337A1 (fr) | 2012-09-05 |
| AU2007249635B2 (en) | 2012-05-31 |
| JP2010500002A (ja) | 2010-01-07 |
| IL238895A0 (en) | 2015-07-30 |
| JP5180845B2 (ja) | 2013-04-10 |
| JP2013027401A (ja) | 2013-02-07 |
| CN101432439A (zh) | 2009-05-13 |
| WO2007133831A2 (fr) | 2007-11-22 |
| EP1994180A2 (fr) | 2008-11-26 |
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