IL258004A - Recombinant listeria vaccine strains and methods of using the same in cancer immunotherapy - Google Patents

Recombinant listeria vaccine strains and methods of using the same in cancer immunotherapy

Info

Publication number
IL258004A
IL258004A IL258004A IL25800418A IL258004A IL 258004 A IL258004 A IL 258004A IL 258004 A IL258004 A IL 258004A IL 25800418 A IL25800418 A IL 25800418A IL 258004 A IL258004 A IL 258004A
Authority
IL
Israel
Prior art keywords
methods
same
cancer immunotherapy
recombinant listeria
vaccine strains
Prior art date
Application number
IL258004A
Other languages
English (en)
Hebrew (he)
Original Assignee
Advaxis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advaxis Inc filed Critical Advaxis Inc
Publication of IL258004A publication Critical patent/IL258004A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0208—Specific bacteria not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL258004A 2015-09-17 2018-03-11 Recombinant listeria vaccine strains and methods of using the same in cancer immunotherapy IL258004A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562219961P 2015-09-17 2015-09-17
PCT/US2016/052322 WO2017049218A2 (fr) 2015-09-17 2016-09-16 Souches vaccinales de listeria de recombinaison et méthodes d'utilisation desdites souches dans l'immunothérapie anticancéreuse

Publications (1)

Publication Number Publication Date
IL258004A true IL258004A (en) 2018-05-31

Family

ID=58289688

Family Applications (1)

Application Number Title Priority Date Filing Date
IL258004A IL258004A (en) 2015-09-17 2018-03-11 Recombinant listeria vaccine strains and methods of using the same in cancer immunotherapy

Country Status (10)

Country Link
EP (1) EP3349789A2 (fr)
JP (1) JP2018527382A (fr)
KR (1) KR20180043381A (fr)
CN (1) CN108348591A (fr)
AU (1) AU2016324170A1 (fr)
CA (1) CA2998889A1 (fr)
IL (1) IL258004A (fr)
MA (1) MA42845A (fr)
MX (1) MX2018003352A (fr)
WO (1) WO2017049218A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9012141B2 (en) 2000-03-27 2015-04-21 Advaxis, Inc. Compositions and methods comprising KLK3 of FOLH1 antigen
WO2012125551A1 (fr) 2011-03-11 2012-09-20 Advaxis Adjuvants à base de listeria
SG10201700392UA (en) 2012-03-12 2017-03-30 Advaxis Inc Suppressor cell function inhibition following listeria vaccine treatment
EP3107566A4 (fr) 2014-02-18 2017-10-11 Advaxis, Inc. Immunothérapie multi-cibles dirigée contre un biomarqueur
SG11201608820WA (en) 2014-04-24 2016-11-29 Advaxis Inc Recombinant listeria vaccine strains and methods of producing the same
MA41644A (fr) 2015-03-03 2018-01-09 Advaxis Inc Compositions à base de listeria comprenant un système d'expression de minigènes codant pour des peptides, et leurs procédés d'utilisation
CN110506107A (zh) 2016-11-30 2019-11-26 阿德瓦希斯公司 靶向复发性癌症突变的免疫原性组合物及其使用方法
US11179339B2 (en) 2017-09-19 2021-11-23 Advaxis, Inc. Compositions and methods for lyophilization of bacteria or listeria strains
CN110499324A (zh) * 2019-09-02 2019-11-26 中生康元生物科技(北京)有限公司 一种用于鉴定肿瘤新抗原的细菌表达载体及筛选鉴定肿瘤新抗原的方法

Also Published As

Publication number Publication date
MA42845A (fr) 2018-07-25
CN108348591A (zh) 2018-07-31
KR20180043381A (ko) 2018-04-27
WO2017049218A2 (fr) 2017-03-23
MX2018003352A (es) 2018-08-15
EP3349789A2 (fr) 2018-07-25
AU2016324170A1 (en) 2018-04-12
JP2018527382A (ja) 2018-09-20
CA2998889A1 (fr) 2017-03-23

Similar Documents

Publication Publication Date Title
IL258563A (en) Recombinant Listera vaccine strains and methods for their use in cancer immunotherapy
IL251624A0 (en) Recombinant immunogenic Listeria strains and their use as cancer immunotherapy methods
IL248483A0 (en) Different strains of Listeria recombinant vaccines and methods for their production
IL258004A (en) Recombinant listeria vaccine strains and methods of using the same in cancer immunotherapy
SG10202101368WA (en) Novel peptides and combination of peptides for use in immunotherapy against various cancers
SG11201706681VA (en) Novel peptides and combination of peptides for use in immunotherapy against various tumors
IL251435A0 (en) Preparations and methods of use for increased immune response and cancer treatment
IL247066A0 (en) Cancer immunotherapy by combining local and systemic immune stimulation
GB201510771D0 (en) Novel peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer
EP3142496A4 (fr) Microorganismes administrés en alimentation directe et leurs procédés d'utilisation
EP3215602A4 (fr) Procédés et matériels pour la production de virus recombinés dans des microalgues eucaryotes
PL3319989T3 (pl) Zastosowanie zmodyfikowanych fragmentów fc w immunoterapii
IL249131A0 (en) A method for reducing the immunogenicity of protein and peptide
IL254129A0 (en) New peptides and a combination of peptides for use in immunotherapy against various tumors
GB201416293D0 (en) Methods and preparations
ZA201604870B (en) Recombinant microorganisms and methods of use thereof
IL287985A (en) A peptide derived from koc1 and a component containing it
IL257335A (en) A depdc1-derived peptide and a component containing it
IL250235A0 (en) A peptide derived from urlc10 and a component containing it
IL250215A0 (en) A peptide derived from cdca1 and a component containing it
HK1237813A1 (en) Recombinant listeria vaccine strains and methods of using the same in cancer immunotherapy
IL247448A0 (en) Peptides and methods of use
HK1257010A1 (en) Fcv recombinant vaccines and uses thereof
AU2015901160A0 (en) Immunomodulatory peptides and methods of use
HK1226743A1 (en) Peptides and methods of use