IL273585A - Therapeutic methods related to HSP90 inhibitors - Google Patents

Therapeutic methods related to HSP90 inhibitors

Info

Publication number
IL273585A
IL273585A IL273585A IL27358520A IL273585A IL 273585 A IL273585 A IL 273585A IL 273585 A IL273585 A IL 273585A IL 27358520 A IL27358520 A IL 27358520A IL 273585 A IL273585 A IL 273585A
Authority
IL
Israel
Prior art keywords
therapeutic methods
methods relating
hsp90 inhibitors
hsp90
inhibitors
Prior art date
Application number
IL273585A
Other languages
English (en)
Hebrew (he)
Original Assignee
Ai Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ai Therapeutics Inc filed Critical Ai Therapeutics Inc
Publication of IL273585A publication Critical patent/IL273585A/en

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    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
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    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
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    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
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    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
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    • A61P35/00—Antineoplastic agents
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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IL273585A 2017-09-27 2020-03-25 Therapeutic methods related to HSP90 inhibitors IL273585A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762563991P 2017-09-27 2017-09-27
US201762587886P 2017-11-17 2017-11-17
US201862688079P 2018-06-21 2018-06-21
PCT/US2018/053025 WO2019067666A1 (fr) 2017-09-27 2018-09-27 Méthodes thérapeutiques se rapportant aux inhibiteurs de hsp90

Publications (1)

Publication Number Publication Date
IL273585A true IL273585A (en) 2020-05-31

Family

ID=63858166

Family Applications (1)

Application Number Title Priority Date Filing Date
IL273585A IL273585A (en) 2017-09-27 2020-03-25 Therapeutic methods related to HSP90 inhibitors

Country Status (13)

Country Link
US (2) US20190091229A1 (fr)
EP (1) EP3687542A1 (fr)
JP (1) JP2020535173A (fr)
KR (1) KR20200077518A (fr)
CN (1) CN111372588A (fr)
AU (1) AU2018341571A1 (fr)
BR (1) BR112020006009A2 (fr)
CA (1) CA3076915A1 (fr)
IL (1) IL273585A (fr)
MX (1) MX2020003959A (fr)
RU (1) RU2020114632A (fr)
TW (1) TW201919634A (fr)
WO (1) WO2019067666A1 (fr)

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WO2020176686A1 (fr) * 2019-02-26 2020-09-03 Oregon Health & Science University Méthodes de traitement de la leucémie aiguë myéloïde résistante au vénétoclax
MX2021011948A (es) * 2019-03-29 2022-01-04 Univ Texas Compuestos con actividad antitumoral contra células cancerígenas que llevan inserciones de exon 20 effr o her2.
EP3771469A1 (fr) * 2019-07-30 2021-02-03 Amgen, Inc Formulations et dosages pour l'administration d'un composé inhibant la protéine mcl1
US11471451B2 (en) * 2019-08-19 2022-10-18 Arog Pharmaceuticals, Inc. Uses of crenolanib
US20220362254A1 (en) * 2019-08-22 2022-11-17 Thomas Jefferson University Methods for reprogramming cancer cells
CA3148413A1 (fr) * 2019-08-23 2021-03-04 Guru Reddy Combinaison de poziotinib avec des inhibiteurs de vegfr2 et ses methodes d'utilisation
WO2021063340A1 (fr) * 2019-09-30 2021-04-08 江苏恒瑞医药股份有限公司 Utilisation d'un inhibiteur d'ezh2 en association avec un inhibiteur de point de contrôle immunitaire et un inhibiteur de tyrosine kinase dans la préparation d'un médicament pour le traitement d'une tumeur
WO2021133862A1 (fr) * 2019-12-24 2021-07-01 The Regents Of The University Of California Ciblage du mécanisme d'apoptose intrinsèque dans le glioblastome
WO2021148396A1 (fr) * 2020-01-20 2021-07-29 Astrazeneca Ab Inhibiteurs de tyrosine kinase du récepteur du facteur de croissance épidermique pour le traitement du cancer
WO2021231405A1 (fr) * 2020-05-12 2021-11-18 Board Of Regents, The University Of Texas System Procédés de traitement du glioblastome
WO2022090547A1 (fr) 2020-10-30 2022-05-05 Dsm Ip Assets B.V. Production de caroténoïdes par fermentation
US11969420B2 (en) * 2020-10-30 2024-04-30 Arog Pharmaceuticals, Inc. Combination therapy of crenolanib and apoptosis pathway agents for the treatment of proliferative disorders
CA3214172A1 (fr) * 2021-04-02 2022-10-06 Mukesh K. Nyati Polytherapie pour le traitement du cancer
US20240390379A1 (en) * 2021-09-29 2024-11-28 University Of Massachusetts EZH2 Inhibition in Pancreatic Cancer
MX2024008057A (es) 2021-12-30 2024-08-28 Biomea Fusion Inc Compuestos de pirazina como inhibidores de flt3.
CN114796503B (zh) * 2022-05-05 2024-05-24 安徽省立医院(中国科学技术大学附属第一医院) Kdm6a抑制剂和酪氨酸激酶抑制剂联合在制备抗肿瘤的药物中的用途

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RU2020114632A3 (fr) 2022-04-18
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BR112020006009A2 (pt) 2020-10-06
CN111372588A (zh) 2020-07-03
KR20200077518A (ko) 2020-06-30
TW201919634A (zh) 2019-06-01
WO2019067666A8 (fr) 2020-04-16
AU2018341571A8 (en) 2020-05-28
MX2020003959A (es) 2020-08-03
US20200253979A1 (en) 2020-08-13
JP2020535173A (ja) 2020-12-03
RU2020114632A (ru) 2021-10-28
EP3687542A1 (fr) 2020-08-05
AU2018341571A1 (en) 2020-04-23

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