IL283990A - Modified oxopyridine derivatives - Google Patents
Modified oxopyridine derivativesInfo
- Publication number
- IL283990A IL283990A IL283990A IL28399021A IL283990A IL 283990 A IL283990 A IL 283990A IL 283990 A IL283990 A IL 283990A IL 28399021 A IL28399021 A IL 28399021A IL 283990 A IL283990 A IL 283990A
- Authority
- IL
- Israel
- Prior art keywords
- oxopyridine derivatives
- substituted oxopyridine
- substituted
- derivatives
- oxopyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2018122825 | 2018-12-21 | ||
| PCT/EP2019/085983 WO2020127504A1 (fr) | 2018-12-21 | 2019-12-18 | Dérivés d'oxopyridine substitués |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL283990A true IL283990A (en) | 2021-07-29 |
Family
ID=69143542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL283990A IL283990A (en) | 2018-12-21 | 2021-06-14 | Modified oxopyridine derivatives |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP3898633A1 (fr) |
| JP (1) | JP2022514303A (fr) |
| KR (1) | KR20210106504A (fr) |
| CN (1) | CN113474348A (fr) |
| AR (1) | AR117435A1 (fr) |
| AU (1) | AU2019407909B2 (fr) |
| BR (1) | BR112021009435A2 (fr) |
| CA (1) | CA3124220A1 (fr) |
| CL (1) | CL2021001613A1 (fr) |
| CO (1) | CO2021007908A2 (fr) |
| CR (1) | CR20210342A (fr) |
| DO (1) | DOP2021000128A (fr) |
| EA (1) | EA202191764A1 (fr) |
| EC (1) | ECSP21043895A (fr) |
| IL (1) | IL283990A (fr) |
| JO (1) | JOP20210161A1 (fr) |
| MA (1) | MA54521A (fr) |
| MX (1) | MX2021007508A (fr) |
| PE (1) | PE20211790A1 (fr) |
| SG (1) | SG11202104384PA (fr) |
| TW (1) | TW202039510A (fr) |
| WO (1) | WO2020127504A1 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11542245B2 (en) * | 2018-03-15 | 2023-01-03 | Bayer Pharma Aktiengesellschaft | Preparative process |
| CN114105881B (zh) | 2020-08-31 | 2024-01-26 | 沈阳海诺威医药科技有限公司 | 血小板聚集抑制剂及其制备方法和用途 |
| US20240174633A1 (en) | 2021-03-09 | 2024-05-30 | Bayer Aktiengesellschaft | Crystalline forms of (4s)-24-chloro-4-ethyl-73-fluoro-35-methoxy-32,5-dioxo-14-(trifluoro-methyl)-32h-6-aza-3(4,1)-pyridina-1(1)-[1,2,3]triazola-2(1,2),7(1)-dibenzenaheptaphane-74-carboxamide |
| WO2022189280A1 (fr) | 2021-03-09 | 2022-09-15 | Bayer Aktiengesellschaft | Solvates de (4s)-24-chloro-4-éthyl-73-fluoro-35-méthoxy-32,5-dioxo-14-(trifluoro-méthyl)-32 h-6- aza-3(4,1)-pyridina-1(1)-[1,2,3]triazola-2(1,2),7(1)-dibenzenaheptaphane-74-carboxamide |
| CA3212644A1 (fr) | 2021-03-09 | 2022-09-15 | Bayer Aktiengesellschaft | Formes posologiques pharmaceutiques comprenant du (4s)-24-chloro-4-ethyl-73-fluoro-35-methoxy-32,5-dioxo-14-(trifluoromethyl)-32h-6-aza-3(4,1)-pyridina-1(1)-[1,2,3]triazola-2(1,2) ,7(1)-dibenzenaheptaphane-74-carboxamide |
| CN114560754A (zh) * | 2022-02-25 | 2022-05-31 | 滁州学院 | 一种烷基醇的制备方法 |
| WO2024223790A1 (fr) * | 2023-04-28 | 2024-10-31 | Basf Se | Utilisation de 4-alcoxypentanoates d'alkyle comme arômes chimiques |
| CN116874469B (zh) * | 2023-09-06 | 2023-11-10 | 成都施贝康生物医药科技有限公司 | 一种氧代吡啶类化合物、中间体及其制备方法和用途 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0420722D0 (en) | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
| DE102006032824A1 (de) * | 2006-07-14 | 2008-01-17 | Bayer Healthcare Ag | Substituierte Indazole |
| US8163779B2 (en) | 2006-12-20 | 2012-04-24 | Takeda San Diego, Inc. | Glucokinase activators |
| WO2014160592A2 (fr) | 2013-03-27 | 2014-10-02 | Merck Sharp & Dohme Corp. | Inhibiteurs du facteur xia |
| TWI633089B (zh) * | 2013-03-28 | 2018-08-21 | 拜耳製藥股份有限公司 | 經取代的酮基吡啶衍生物 |
| CA2918814C (fr) | 2013-07-23 | 2021-10-12 | Bayer Pharma Aktiengesellschaft | Derives de l'oxopyridine substitues et utilisation desdits derives comme facteur xia/plasma |
| EP3063150B1 (fr) | 2013-10-30 | 2017-11-22 | Bayer Pharma Aktiengesellschaft | Dérivés d'oxopyridine substituée |
| EP3197872B1 (fr) | 2014-09-24 | 2019-01-30 | Bayer Pharma Aktiengesellschaft | (2h)-2-oxopyridines en tant qu'inhibiteurs du facteur xia pour le traitement de maladies thrombotiques |
| US10414731B2 (en) | 2014-09-24 | 2019-09-17 | Bayer Pharma Aktiengesellschaft | Substituted oxopyridine derivatives |
| EP3197889B1 (fr) | 2014-09-24 | 2018-08-01 | Bayer Pharma Aktiengesellschaft | Dérivés d'oxopyridine substitués |
| US10077265B2 (en) * | 2014-09-24 | 2018-09-18 | Bayer Pharma Aktiengesellschaft | Substituted oxopyridine derivatives |
| CN106687458B (zh) | 2014-09-24 | 2020-10-27 | 拜耳制药股份公司 | 取代的氧代吡啶衍生物 |
| EP3197891B1 (fr) | 2014-09-24 | 2018-11-21 | Bayer Pharma Aktiengesellschaft | Dérivés de pyridobenzazépine et de pyridobenzazocine inhibant le facteur xia |
| CA2979937A1 (fr) * | 2015-03-19 | 2016-09-22 | Bayer Pharma Aktiengesellschaft | Derives d'oxopyridine comme inhibiteurs du facteur xia pour le traitement de la thrombose |
| JO3703B1 (ar) | 2015-07-09 | 2021-01-31 | Bayer Pharma AG | مشتقات أوكسوبيريدين مستبدلة |
| EP3344618A1 (fr) | 2015-09-04 | 2018-07-11 | Bayer Pharma Aktiengesellschaft | Dérivés d'oxopyridine substitués |
-
2019
- 2019-12-18 CN CN201980091518.1A patent/CN113474348A/zh active Pending
- 2019-12-18 JP JP2021535063A patent/JP2022514303A/ja active Pending
- 2019-12-18 WO PCT/EP2019/085983 patent/WO2020127504A1/fr not_active Ceased
- 2019-12-18 KR KR1020217022510A patent/KR20210106504A/ko not_active Ceased
- 2019-12-18 AR ARP190103745A patent/AR117435A1/es unknown
- 2019-12-18 TW TW108146372A patent/TW202039510A/zh unknown
- 2019-12-18 MA MA054521A patent/MA54521A/fr unknown
- 2019-12-18 JO JOP/2021/0161A patent/JOP20210161A1/ar unknown
- 2019-12-18 EA EA202191764A patent/EA202191764A1/ru unknown
- 2019-12-18 PE PE2021000903A patent/PE20211790A1/es unknown
- 2019-12-18 CR CR20210342A patent/CR20210342A/es unknown
- 2019-12-18 MX MX2021007508A patent/MX2021007508A/es unknown
- 2019-12-18 BR BR112021009435-0A patent/BR112021009435A2/pt not_active Application Discontinuation
- 2019-12-18 EP EP19832641.5A patent/EP3898633A1/fr not_active Withdrawn
- 2019-12-18 AU AU2019407909A patent/AU2019407909B2/en not_active Ceased
- 2019-12-18 CA CA3124220A patent/CA3124220A1/fr active Pending
- 2019-12-18 SG SG11202104384PA patent/SG11202104384PA/en unknown
-
2021
- 2021-06-14 IL IL283990A patent/IL283990A/en unknown
- 2021-06-16 EC ECSENADI202143895A patent/ECSP21043895A/es unknown
- 2021-06-16 CO CONC2021/0007908A patent/CO2021007908A2/es unknown
- 2021-06-17 CL CL2021001613A patent/CL2021001613A1/es unknown
- 2021-06-18 DO DO2021000128A patent/DOP2021000128A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20210106504A (ko) | 2021-08-30 |
| MX2021007508A (es) | 2021-08-05 |
| AU2019407909A1 (en) | 2021-05-27 |
| CO2021007908A2 (es) | 2021-07-19 |
| DOP2021000128A (es) | 2021-09-30 |
| AU2019407909B2 (en) | 2023-05-25 |
| CL2021001613A1 (es) | 2021-12-03 |
| JOP20210161A1 (ar) | 2023-01-30 |
| SG11202104384PA (en) | 2021-05-28 |
| CA3124220A1 (fr) | 2020-06-25 |
| PE20211790A1 (es) | 2021-09-09 |
| EP3898633A1 (fr) | 2021-10-27 |
| ECSP21043895A (es) | 2021-07-30 |
| TW202039510A (zh) | 2020-11-01 |
| MA54521A (fr) | 2022-03-30 |
| CR20210342A (es) | 2021-08-09 |
| WO2020127504A1 (fr) | 2020-06-25 |
| JP2022514303A (ja) | 2022-02-10 |
| CN113474348A (zh) | 2021-10-01 |
| BR112021009435A2 (pt) | 2021-08-17 |
| EA202191764A1 (ru) | 2021-10-22 |
| AR117435A1 (es) | 2021-08-04 |
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