IL289475B2 - Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases - Google Patents

Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases

Info

Publication number
IL289475B2
IL289475B2 IL289475A IL28947521A IL289475B2 IL 289475 B2 IL289475 B2 IL 289475B2 IL 289475 A IL289475 A IL 289475A IL 28947521 A IL28947521 A IL 28947521A IL 289475 B2 IL289475 B2 IL 289475B2
Authority
IL
Israel
Prior art keywords
protein
cells
fusion protein
fusion
igg
Prior art date
Application number
IL289475A
Other languages
English (en)
Hebrew (he)
Other versions
IL289475A (en
IL289475B1 (en
Original Assignee
Delinia Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55163946&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL289475(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Delinia Inc filed Critical Delinia Inc
Publication of IL289475A publication Critical patent/IL289475A/en
Publication of IL289475B1 publication Critical patent/IL289475B1/en
Publication of IL289475B2 publication Critical patent/IL289475B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL289475A 2014-07-21 2015-07-20 Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases IL289475B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461999241P 2014-07-21 2014-07-21
PCT/US2015/041177 WO2016014428A2 (en) 2014-07-21 2015-07-20 Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases

Publications (3)

Publication Number Publication Date
IL289475A IL289475A (en) 2022-02-01
IL289475B1 IL289475B1 (en) 2023-06-01
IL289475B2 true IL289475B2 (en) 2023-10-01

Family

ID=55163946

Family Applications (3)

Application Number Title Priority Date Filing Date
IL289475A IL289475B2 (en) 2014-07-21 2015-07-20 Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases
IL250024A IL250024B (en) 2014-07-21 2017-01-10 Molecules that activate t cells are selectively regulated for the treatment of autoimmune diseases
IL278299A IL278299B (en) 2014-07-21 2020-10-26 Molecules that activate t cells are selectively regulated for the treatment of autoimmune diseases

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL250024A IL250024B (en) 2014-07-21 2017-01-10 Molecules that activate t cells are selectively regulated for the treatment of autoimmune diseases
IL278299A IL278299B (en) 2014-07-21 2020-10-26 Molecules that activate t cells are selectively regulated for the treatment of autoimmune diseases

Country Status (22)

Country Link
US (6) US20170037102A1 (2)
EP (2) EP3172227B9 (2)
JP (2) JP6768633B2 (2)
KR (1) KR102493543B1 (2)
CN (2) CN106795213B (2)
AU (3) AU2015292889C1 (2)
CA (1) CA2954847A1 (2)
DK (1) DK3172227T3 (2)
EA (2) EA202190903A3 (2)
ES (1) ES2763198T3 (2)
GB (1) GB2538666A (2)
HU (1) HUE046065T2 (2)
IL (3) IL289475B2 (2)
LT (1) LT3172227T (2)
MX (2) MX378790B (2)
PL (1) PL3172227T3 (2)
PT (1) PT3172227T (2)
RS (1) RS59789B1 (2)
SG (2) SG10202010158TA (2)
SI (1) SI3172227T1 (2)
WO (1) WO2016014428A2 (2)
ZA (1) ZA201700344B (2)

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