IL292459A - Treatment of liver disorders - Google Patents
Treatment of liver disordersInfo
- Publication number
- IL292459A IL292459A IL292459A IL29245922A IL292459A IL 292459 A IL292459 A IL 292459A IL 292459 A IL292459 A IL 292459A IL 29245922 A IL29245922 A IL 29245922A IL 292459 A IL292459 A IL 292459A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- liver
- patient
- formula
- pharmaceutically acceptable
- Prior art date
Links
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
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- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| US201962933277P | 2019-11-08 | 2019-11-08 | |
| US202063004403P | 2020-04-02 | 2020-04-02 | |
| PCT/US2020/059522 WO2021092474A1 (en) | 2019-11-08 | 2020-11-06 | Treating liver disorders |
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| IL292459A true IL292459A (en) | 2022-06-01 |
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| JP (1) | JP2023501386A (de) |
| KR (1) | KR20220098168A (de) |
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| CL (1) | CL2022001167A1 (de) |
| IL (1) | IL292459A (de) |
| MX (1) | MX2022005407A (de) |
| WO (1) | WO2021092474A1 (de) |
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| CA3201466A1 (en) | 2020-12-14 | 2022-06-23 | Regeneron Pharmaceuticals, Inc. | Methods of treating metabolic disorders and cardiovascular disease with inhibin subunit beta e (inhbe) inhibitors |
| TW202539702A (zh) * | 2024-03-08 | 2025-10-16 | 大陸商上海拓界生物醫藥科技有限公司 | 靶向ＩＮＨＢＥ的ＲＮＡｉ劑 |
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| TW200906823A (en) * | 2007-07-16 | 2009-02-16 | Lilly Co Eli | Compounds and methods for modulating FXR |
| US20140187633A1 (en) * | 2012-12-31 | 2014-07-03 | Amarin Pharmaceuticals Ireland Limited | Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis |
| US11419878B2 (en) * | 2016-03-28 | 2022-08-23 | Intercept Pharmaceuticals, Inc. | Medicine obtained by combining FXR agonist and ARB |
| WO2018170173A1 (en) * | 2017-03-15 | 2018-09-20 | Metacrine, Inc. | Farnesoid x receptor agonists and uses thereof |
| US20210121493A1 (en) * | 2017-07-25 | 2021-04-29 | Cedars-Sinai Medical Center | Methods for treating liver diseases |
| EP3844156A4 (de) * | 2018-08-30 | 2022-06-08 | Terns Pharmaceuticals, Inc. | Behandlung von lebererkrankungen |
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2020
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- 2020-11-06 WO PCT/US2020/059522 patent/WO2021092474A1/en not_active Ceased
- 2020-11-06 CA CA3160445A patent/CA3160445A1/en active Pending
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| EP4054567A4 (de) | 2024-01-10 |
| MX2022005407A (es) | 2022-05-24 |
| JP2023501386A (ja) | 2023-01-18 |
| CL2022001167A1 (es) | 2023-02-10 |
| BR112022008639A2 (pt) | 2022-07-19 |
| KR20220098168A (ko) | 2022-07-11 |
| WO2021092474A1 (en) | 2021-05-14 |
| EP4054567A1 (de) | 2022-09-14 |
| AU2020380968A1 (en) | 2022-05-12 |
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