IL296531A - שיטה לטיפול בסרטן גליומה על ידי שימוש באנטגוניסטים לקולטן ampa תלוי tarp גמא 8 - Google Patents

שיטה לטיפול בסרטן גליומה על ידי שימוש באנטגוניסטים לקולטן ampa תלוי tarp גמא 8

Info

Publication number: IL296531A
Authority: IL; Israel
Prior art keywords: glioma; methyl; acid; tumo; cancer
Prior art date: 2020-03-16

Application number

IL296531A

Other languages

English (en)

Original Assignee

Es Therapeutics Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2020-03-16

Filing date

2021-03-15

Publication date

2022-11-01

2021-03-15 Application filed by Es Therapeutics Llc filed Critical Es Therapeutics Llc

2022-11-01 Publication of IL296531A publication Critical patent/IL296531A/he

Links

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RYYVLZVUVIJVGH-UHFFFAOYSA-N trimethylxanthine Natural products CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

IL296531A 2020-03-16 2021-03-15 שיטה לטיפול בסרטן גליומה על ידי שימוש באנטגוניסטים לקולטן ampa תלוי tarp גמא 8 IL296531A (he)

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Application Number	Priority Date	Filing Date	Title
US202062990327P	2020-03-16	2020-03-16
US202063031347P	2020-05-28	2020-05-28
PCT/US2021/022356 WO2021188431A1 (en)	2020-03-16	2021-03-15	Method of treating glioma cancer using tarp gamma 8-dependent ampa receptor antagonists

Publications (1)

Publication Number	Publication Date
IL296531A true IL296531A (he)	2022-11-01

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IL (1)	IL296531A (he)
WO (1)	WO2021188431A1 (he)

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW201609719A (zh) *	2014-05-28	2016-03-16	美國禮來大藥廠	作為ＴＡＲＰ－γ８依賴性ＡＭＰＡ受體拮抗劑之６－經取代－３Ｈ－１，３－苯并噻唑－２－酮化合物
CA3145507A1 (en) *	2018-07-27	2020-01-30	Daniel Pierce RADIN	Clinical methods and pharmaceutical compositions employing ampa receptor antagonists to treat glioblastoma and other cancers

2021
- 2021-03-15 IL IL296531A patent/IL296531A/he unknown
- 2021-03-15 WO PCT/US2021/022356 patent/WO2021188431A1/en not_active Ceased

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Publication number	Publication date
WO2021188431A1 (en)	2021-09-23

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