IL301912A - System and method for removal of immune inhibitors from biological fluids - Google Patents

System and method for removal of immune inhibitors from biological fluids

Info

Publication number
IL301912A
IL301912A IL301912A IL30191223A IL301912A IL 301912 A IL301912 A IL 301912A IL 301912 A IL301912 A IL 301912A IL 30191223 A IL30191223 A IL 30191223A IL 301912 A IL301912 A IL 301912A
Authority
IL
Israel
Prior art keywords
column
capture
tnf
plasma
stnf
Prior art date
Application number
IL301912A
Other languages
English (en)
Hebrew (he)
Original Assignee
Immunicom Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunicom Inc filed Critical Immunicom Inc
Publication of IL301912A publication Critical patent/IL301912A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/362Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits changing physical properties of target cells by binding them to added particles to facilitate their subsequent separation from other cells, e.g. immunoaffinity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3687Chemical treatment
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/525Tumour necrosis factor [TNF]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • A61M2202/0413Blood
    • A61M2202/0415Plasma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/75General characteristics of the apparatus with filters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Cell Biology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • External Artificial Organs (AREA)
IL301912A 2019-11-19 2019-11-19 System and method for removal of immune inhibitors from biological fluids IL301912A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2019/062177 WO2021101519A1 (fr) 2019-11-19 2019-11-19 Système et méthode pour l'élimination d'inhibiteurs immunitaires de fluides biologiques

Publications (1)

Publication Number Publication Date
IL301912A true IL301912A (en) 2023-06-01

Family

ID=75980821

Family Applications (2)

Application Number Title Priority Date Filing Date
IL301912A IL301912A (en) 2019-11-19 2019-11-19 System and method for removal of immune inhibitors from biological fluids
IL289438A IL289438B2 (en) 2019-11-19 2019-11-19 System and method for removing immunosuppressants from biological fluids

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL289438A IL289438B2 (en) 2019-11-19 2019-11-19 System and method for removing immunosuppressants from biological fluids

Country Status (8)

Country Link
EP (1) EP3846875A4 (fr)
JP (2) JP7159493B2 (fr)
KR (2) KR102491518B1 (fr)
CN (1) CN114650852B (fr)
AU (3) AU2019474912B2 (fr)
CA (2) CA3153685C (fr)
IL (2) IL301912A (fr)
WO (1) WO2021101519A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11224858B1 (en) 2020-10-01 2022-01-18 Immunicom, Inc. Reduced leaching of a ligand
WO2022071960A1 (fr) * 2020-10-01 2022-04-07 Immunicom, Inc. Lixiviation réduite d'un ligand
JP7632141B2 (ja) * 2021-07-14 2025-02-19 東レ株式会社 モジュール

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2213079C (fr) 1995-02-16 2004-12-14 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Adsorbant du facteur .alpha. de necrose tumorale, procede permettant de l'eliminer par adsorption et dispositif d'adsorption utilisant ledit adsorbant
US8197430B1 (en) * 1998-05-22 2012-06-12 Biopheresis Technologies, Inc. Method and system to remove cytokine inhibitor in patients
JP4150838B2 (ja) * 1999-11-02 2008-09-17 株式会社カネカ 充填物流出防止用フィルタ及びそれを装着した吸着器
WO2004064608A2 (fr) * 2003-01-17 2004-08-05 Aethlon Medical, Inc. Procede de suppression de virus dans le sang par hemodialyse a affinite pour les lectines
JP2006288571A (ja) 2005-04-08 2006-10-26 Toray Ind Inc 癌治療用吸着材および体外循環カラム
JP4925159B2 (ja) * 2005-10-12 2012-04-25 日機装株式会社 血液浄化装置
DK3789056T3 (da) * 2007-08-31 2025-06-23 Seastar Medical Inc Indretninger til selektiv cytoferese
JP2009178523A (ja) 2008-02-01 2009-08-13 Kaneka Corp 可溶性腫瘍壊死因子受容体の吸着材、吸着方法および吸着装置
JP5341559B2 (ja) 2009-03-03 2013-11-13 和雄 寺本 多孔性吸着材
US9717841B2 (en) * 2012-09-11 2017-08-01 Gary L. McNeil Closed-circuit device and methods for isolation, modification, and re-administration of specific constituents from a biological fluid source
US9227005B2 (en) 2013-03-14 2016-01-05 Brian J LeBerthon Method and device for treating cancer
US20170014450A1 (en) 2014-02-28 2017-01-19 Exosome Sciences, Inc. Brain specific exosome based diagnostics and extracorporeal therapies
JP6480447B2 (ja) * 2014-07-22 2019-03-13 旭化成メディカル株式会社 ヒストンを除去する吸着材及び生体由来液浄化デバイス
JP2018509994A (ja) 2015-03-27 2018-04-12 エリアス・セラピューティクス・インコーポレイテッドEliaz Therapeutics,Inc. 患者選択的アフェレシス
HUE064189T2 (hu) 2016-07-28 2024-02-28 Captec Medical Kft Áramlásból befogó eszköz sejtek vérbõl történõ eltávolítására
US20190247560A1 (en) * 2018-02-13 2019-08-15 Gambro Lundia Ab Extracorporeal devices and methods of treating complement factor related diseases
DE102018104177A1 (de) * 2018-02-23 2019-08-29 B. Braun Avitum Ag Vorrichtung zur Entfernung von Noxen aus Blut, extrakorporales Perfusionssystem mit einer solchen Vorrichtung sowie Verfahren zur Herstellung einer solchen Vorrichtung
IL317026A (en) * 2018-02-28 2025-01-01 Plas Free Ltd In vitro device and matrix for removing fibrinolytic proteins from biological fluids, methods and uses thereof

Also Published As

Publication number Publication date
EP3846875A1 (fr) 2021-07-14
JP2023015053A (ja) 2023-01-31
CA3165330A1 (fr) 2021-05-27
IL289438B2 (en) 2023-09-01
CN114650852B (zh) 2024-08-06
AU2019474912B2 (en) 2022-02-17
JP7159493B2 (ja) 2022-10-24
AU2022203249A1 (en) 2022-06-23
CA3153685A1 (fr) 2021-05-27
AU2019474912A1 (en) 2022-01-06
KR20220039724A (ko) 2022-03-29
KR20230016032A (ko) 2023-01-31
AU2023274130A1 (en) 2023-12-21
JP7514281B2 (ja) 2024-07-10
EP3846875A4 (fr) 2021-07-14
CA3153685C (fr) 2022-10-11
CN114650852A (zh) 2022-06-21
IL289438B1 (en) 2023-05-01
KR102491518B1 (ko) 2023-01-20
IL289438A (en) 2022-02-01
JP2022535604A (ja) 2022-08-09
WO2021101519A1 (fr) 2021-05-27
AU2022203249B2 (en) 2023-08-31

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