IL302948A - תכשירים למתן מעכבים של cgrp - Google Patents

תכשירים למתן מעכבים של cgrp

Info

Publication number: IL302948A
Authority: IL; Israel
Prior art keywords: pharmaceutical composition; composition according; cgrp; weight; alkyl glycoside
Prior art date: 2020-11-19

Application number

IL302948A

Other languages

English (en)

Inventor

Charles M Conway

Gene M Dubowchik

Rajesh Kumar

Original Assignee

Pfizer Ireland Pharmaceuticals

Charles M Conway

Gene M Dubowchik

Rajesh Kumar

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2020-11-19

Filing date

2021-11-18

Publication date

2023-07-01

2021-11-18 Application filed by Pfizer Ireland Pharmaceuticals, Charles M Conway, Gene M Dubowchik, Rajesh Kumar filed Critical Pfizer Ireland Pharmaceuticals

2023-07-01 Publication of IL302948A publication Critical patent/IL302948A/he

Links

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-1 alkyl glycoside Chemical class 0.000 claims description 108
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JJVAPHYEOZSKJZ-JGCGQSQUSA-N n-[(2r)-3-(7-methyl-1h-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4-(2-oxo-1h-quinolin-3-yl)piperidine-1-carboxamide Chemical group C1CN(C)CCC1N1CCN(C(=O)[C@@H](CC=2C=C3C=NNC3=C(C)C=2)NC(=O)N2CCC(CC2)C=2C(NC3=CC=CC=C3C=2)=O)CC1 JJVAPHYEOZSKJZ-JGCGQSQUSA-N 0.000 claims description 71
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2063—Proteins, e.g. gelatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Nutrition Science (AREA)
Physiology (AREA)
Pain & Pain Management (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)

IL302948A 2020-11-19 2021-11-18 תכשירים למתן מעכבים של cgrp IL302948A (he)

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US202063115789P	2020-11-19	2020-11-19
US202063126550P	2020-12-17	2020-12-17
PCT/US2021/059801 WO2022109077A1 (en)	2020-11-19	2021-11-18	Compositions for improved delivery of cgrp inhibitors

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EP (1)	EP4247364A4 (he)
JP (1)	JP2023551146A (he)
KR (1)	KR20230088442A (he)
AU (1)	AU2021385052A1 (he)
CA (1)	CA3202137A1 (he)
IL (1)	IL302948A (he)
MX (1)	MX2023005846A (he)
WO (1)	WO2022109077A1 (he)
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CN117503704B (zh) *	2023-11-09	2025-07-11	广州新济药业科技有限公司	一种作用于中枢神经系统的鼻喷雾剂及其制备方法及应用

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2021
- 2021-11-18 WO PCT/US2021/059801 patent/WO2022109077A1/en not_active Ceased
- 2021-11-18 EP EP21895549.0A patent/EP4247364A4/en active Pending
- 2021-11-18 IL IL302948A patent/IL302948A/he unknown
- 2021-11-18 AU AU2021385052A patent/AU2021385052A1/en not_active Abandoned
- 2021-11-18 CA CA3202137A patent/CA3202137A1/en active Pending
- 2021-11-18 JP JP2023529881A patent/JP2023551146A/ja active Pending
- 2021-11-18 KR KR1020237016343A patent/KR20230088442A/ko not_active Ceased
- 2021-11-18 MX MX2023005846A patent/MX2023005846A/es unknown
2023
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Publication number	Publication date
JP2023551146A (ja)	2023-12-07
ZA202304727B (en)	2023-12-20
MX2023005846A (es)	2023-06-02
AU2021385052A9 (en)	2024-05-02
KR20230088442A (ko)	2023-06-19
AU2021385052A1 (en)	2023-06-01
CA3202137A1 (en)	2022-05-27
EP4247364A4 (en)	2024-10-23
WO2022109077A1 (en)	2022-05-27
EP4247364A1 (en)	2023-09-27

Publication	Publication Date	Title
JP5752048B2 (ja)	2015-07-22	薬物投与のための組成物
US10512694B2 (en)	2019-12-24	Compositions for oral drug administration
US8440631B2 (en)	2013-05-14	Compositions for drug administration
IL303817A (he)	2023-08-01	תכשירים להעברה משופרת של מעכבי cgrp
US20090047347A1 (en)	2009-02-19	Compositions for Drug Administration
IL302948A (he)	2023-07-01	תכשירים למתן מעכבים של cgrp
MX2007012642A (es)	2008-01-11	Composiciones farmaceuticas que tienen perfiles mejorados de disolucion para farmacos poco solubles.
US20110046058A1 (en)	2011-02-24	Compositions for enteral absorption and sustained action of leptin-related peptides useful in the treatment of obesity and leptin-modulated disease
US20180000942A1 (en)	2018-01-04	Compositions for drug administration
WO2012066347A1 (en)	2012-05-24	Oil based formulations
HK1164059B (en)	2016-05-20	Compositions for drug administration