IL319974A - מלחי מלונאט וגליקולאט של מעכב egfr - Google Patents
מלחי מלונאט וגליקולאט של מעכב egfrInfo
- Publication number
- IL319974A IL319974A IL319974A IL31997425A IL319974A IL 319974 A IL319974 A IL 319974A IL 319974 A IL319974 A IL 319974A IL 31997425 A IL31997425 A IL 31997425A IL 319974 A IL319974 A IL 319974A
- Authority
- IL
- Israel
- Prior art keywords
- malonate
- egfr inhibitor
- glycolate salts
- glycolate
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/02—Dicarboxylic acids
- C07C55/08—Malonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/06—Glycolic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263422365P | 2022-11-03 | 2022-11-03 | |
| US202363464133P | 2023-05-04 | 2023-05-04 | |
| US202363591670P | 2023-10-19 | 2023-10-19 | |
| PCT/US2023/078473 WO2024097848A1 (en) | 2022-11-03 | 2023-11-02 | Malonate and glycolate salts of an egfr inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL319974A true IL319974A (he) | 2025-05-01 |
Family
ID=89164547
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL319974A IL319974A (he) | 2022-11-03 | 2023-11-02 | מלחי מלונאט וגליקולאט של מעכב egfr |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP4611902A1 (he) |
| JP (1) | JP2025538076A (he) |
| KR (1) | KR20250093563A (he) |
| CN (1) | CN120569380A (he) |
| AU (1) | AU2023372570A1 (he) |
| IL (1) | IL319974A (he) |
| MX (1) | MX2025004240A (he) |
| WO (1) | WO2024097848A1 (he) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024233313A1 (en) * | 2023-05-05 | 2024-11-14 | Oric Pharmaceuticals, Inc. | Egfr inhibitor for treating cancers comprising atypical egfr mutations |
| WO2026080372A1 (en) * | 2024-10-07 | 2026-04-16 | Oric Pharmaceuticals, Inc. | Treatment of cancers comprising egfr extracellular and transmembrane mutations |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0408689B8 (pt) | 2003-03-25 | 2021-05-25 | Laboratoires Fournier S A | derivados de benzenosulfonamida, método para preparação e utilização disso para o tratamento da dor |
| PT3943491T (pt) | 2019-03-19 | 2025-07-28 | Voronoi Inc | Derivado de heteroarilo, método para a produção do mesmo e composição farmacêutica que compreende o mesmo como componente eficaz |
-
2023
- 2023-11-02 IL IL319974A patent/IL319974A/he unknown
- 2023-11-02 JP JP2025519133A patent/JP2025538076A/ja active Pending
- 2023-11-02 KR KR1020257017769A patent/KR20250093563A/ko active Pending
- 2023-11-02 AU AU2023372570A patent/AU2023372570A1/en active Pending
- 2023-11-02 WO PCT/US2023/078473 patent/WO2024097848A1/en not_active Ceased
- 2023-11-02 CN CN202380076911.XA patent/CN120569380A/zh active Pending
- 2023-11-02 EP EP23821415.9A patent/EP4611902A1/en active Pending
-
2025
- 2025-04-10 MX MX2025004240A patent/MX2025004240A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2025538076A (ja) | 2025-11-26 |
| CN120569380A (zh) | 2025-08-29 |
| WO2024097848A1 (en) | 2024-05-10 |
| AU2023372570A1 (en) | 2025-04-17 |
| EP4611902A1 (en) | 2025-09-10 |
| KR20250093563A (ko) | 2025-06-24 |
| MX2025004240A (es) | 2025-07-01 |
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