IL322429A - 5-מתוקסי-n,n-דימתילטריפטמין לטיפול בדיכאון לאחר לידה - Google Patents

5-מתוקסי-n,n-דימתילטריפטמין לטיפול בדיכאון לאחר לידה

Info

Publication number
IL322429A
IL322429A IL322429A IL32242925A IL322429A IL 322429 A IL322429 A IL 322429A IL 322429 A IL322429 A IL 322429A IL 32242925 A IL32242925 A IL 32242925A IL 322429 A IL322429 A IL 322429A
Authority
IL
Israel
Prior art keywords
dmt
meo
pharmaceutically acceptable
acceptable salt
score
Prior art date
Application number
IL322429A
Other languages
English (en)
Inventor
Theis Terwey
Conor Burke
Naoise Gaffney
Original Assignee
Gh Res Ireland Limited
Theis Terwey
Conor Burke
Naoise Gaffney
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2023/057883 external-priority patent/WO2023186835A1/en
Application filed by Gh Res Ireland Limited, Theis Terwey, Conor Burke, Naoise Gaffney filed Critical Gh Res Ireland Limited
Publication of IL322429A publication Critical patent/IL322429A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
IL322429A 2023-01-30 2023-09-27 5-מתוקסי-n,n-דימתילטריפטמין לטיפול בדיכאון לאחר לידה IL322429A (he)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP23153939 2023-01-30
EP23153995 2023-01-30
PCT/EP2023/057883 WO2023186835A1 (en) 2022-03-27 2023-03-27 Treatment of mental disorders
PCT/EP2023/057873 WO2023186826A1 (en) 2022-03-27 2023-03-27 5-meo-dmt for use in the treatment of postpartum depression
PCT/EP2023/076817 WO2024160390A1 (en) 2023-01-30 2023-09-27 5-methoxy-n,n-dimethyltryptamine for the treatment of postpartum depression

Publications (1)

Publication Number Publication Date
IL322429A true IL322429A (he) 2025-09-01

Family

ID=88206855

Family Applications (2)

Application Number Title Priority Date Filing Date
IL322428A IL322428A (he) 2023-01-30 2023-09-27 5-מתוקסי-n,n-דימתילטריפטמין לשימוש בטיפול בהפרעות נפשיות אצל אמהות מניקות
IL322429A IL322429A (he) 2023-01-30 2023-09-27 5-מתוקסי-n,n-דימתילטריפטמין לטיפול בדיכאון לאחר לידה

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL322428A IL322428A (he) 2023-01-30 2023-09-27 5-מתוקסי-n,n-דימתילטריפטמין לשימוש בטיפול בהפרעות נפשיות אצל אמהות מניקות

Country Status (8)

Country Link
EP (2) EP4658265A1 (he)
JP (2) JP2026506513A (he)
KR (2) KR20250139377A (he)
CN (2) CN120712084A (he)
AU (2) AU2023427437A1 (he)
IL (2) IL322428A (he)
MX (2) MX2025008755A (he)
WO (2) WO2024160389A1 (he)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4155306A1 (en) 2021-01-15 2023-03-29 Beckley Psytech Limited Neuroactive ergoline analogue
US12534441B2 (en) 2021-01-15 2026-01-27 Beckley Psytech Limited Tryptamine analogues
US11312684B1 (en) 2021-02-10 2022-04-26 Eleusis Therapeutics Us, Inc. Pharmaceutically acceptable salts of psilocin and uses thereof
US12264131B2 (en) 2022-08-19 2025-04-01 Beckley Psytech Limited Pharmaceutically acceptable salts and compositions thereof
US12246005B2 (en) 2023-06-13 2025-03-11 Beckley Psytech Limited 5-methoxy-n,n-dimethyltryptamine (5-MeO-DMT) formulations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19803376C1 (de) 1998-01-29 1999-10-14 Markus Storz Inhalator zur Erzeugung von aroma- und/oder wirkstoffhaltigen Dämpfen aus Pflanzenmaterial und/oder Flüssigkeiten
US20030051728A1 (en) 2001-06-05 2003-03-20 Lloyd Peter M. Method and device for delivering a physiologically active compound
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US20040234916A1 (en) 2003-05-21 2004-11-25 Alexza Molecular Delivery Corporation Optically ignited or electrically ignited self-contained heating unit and drug-supply unit employing same
ES2355983T3 (es) 2006-08-01 2011-04-01 STOBI GMBH & CO. KG Balón de válvula para inhaladores .
HUE069534T2 (hu) * 2019-02-22 2025-03-28 Gh Res Ireland Limited 5-Metoxi-N,N-dimetiltriptamint (5-MeO-DMT) tartalmazó készítmény mentális rendellenességek kezelésében történõ alkalmazásra
FI4349407T3 (fi) 2019-02-22 2025-06-02 Gh Res Ireland Limited 5-metoksi-n,n-dimetyylitryptamiini (5-meo-dmt) vaikean masennuksen hoitoon
EP3868364A1 (en) * 2020-02-24 2021-08-25 GH Research Limited Aerosol comprising 5-methoxy-n,n-dimethyltryptamine
US11406619B2 (en) * 2020-08-28 2022-08-09 Small Pharma Ltd Injectable formulations

Also Published As

Publication number Publication date
EP4658266A1 (en) 2025-12-10
MX2025008728A (es) 2025-10-01
AU2023427437A1 (en) 2025-09-18
MX2025008755A (es) 2025-11-03
AU2023426967A1 (en) 2025-09-18
JP2026506513A (ja) 2026-02-25
CN120712084A (zh) 2025-09-26
KR20250135903A (ko) 2025-09-15
IL322428A (he) 2025-09-01
JP2026505779A (ja) 2026-02-18
EP4658265A1 (en) 2025-12-10
WO2024160390A1 (en) 2024-08-08
WO2024160389A1 (en) 2024-08-08
CN120813348A (zh) 2025-10-17
KR20250139377A (ko) 2025-09-23

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