IL57497A - 1-phenyl-2-aminoethanol derivatives,their preparation and pharmaceutical compositions comprising them - Google Patents

1-phenyl-2-aminoethanol derivatives,their preparation and pharmaceutical compositions comprising them

Info

Publication number: IL57497A
Authority: IL; Israel
Prior art keywords: sup; phenyl; sub; derivatives; pharmaceutical compositions
Prior art date: 1978-06-15

Application number

IL57497A

Other languages

English (en)

Other versions

IL57497A0 (en

Original Assignee

Ici Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-06-15

Filing date

1979-06-06

Publication date

1982-09-30

1979-06-06 Application filed by Ici Ltd filed Critical Ici Ltd

1979-10-31 Publication of IL57497A0 publication Critical patent/IL57497A0/xx

1982-09-30 Publication of IL57497A publication Critical patent/IL57497A/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
ULSIYEODSMZIPX-UHFFFAOYSA-N phenylethanolamine Chemical class NCC(O)C1=CC=CC=C1 ULSIYEODSMZIPX-UHFFFAOYSA-N 0.000 title abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000002947 alkylene group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
-1 phenylacetyl Chemical group 0.000 abstract 2
125000004182 2-chlorophenyl group Chemical group [H]C1=C([H])C(Cl)=C(*)C([H])=C1[H] 0.000 abstract 1
201000004624 Dermatitis Diseases 0.000 abstract 1
GAEURJUXPZEDJX-UHFFFAOYSA-N [4-[2-[[1-[(2-benzamidoacetyl)amino]-2-methylpropan-2-yl]amino]-1-hydroxyethyl]-2-(2,2-dimethylpropanoyloxy)phenyl] 2,2-dimethylpropanoate Chemical compound C1=C(OC(=O)C(C)(C)C)C(OC(=O)C(C)(C)C)=CC=C1C(O)CNC(C)(C)CNC(=O)CNC(=O)C1=CC=CC=C1 GAEURJUXPZEDJX-UHFFFAOYSA-N 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Dermatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

IL57497A 1978-06-15 1979-06-06 1-phenyl-2-aminoethanol derivatives,their preparation and pharmaceutical compositions comprising them IL57497A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB7827026		1978-06-15

Publications (2)

Publication Number	Publication Date
IL57497A0 IL57497A0 (en)	1979-10-31
IL57497A true IL57497A (en)	1982-09-30

Family

ID=10497984

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL57497A IL57497A (en)	1978-06-15	1979-06-06	1-phenyl-2-aminoethanol derivatives,their preparation and pharmaceutical compositions comprising them

Country Status (12)

Country	Link
US (1)	US4303649A (de)
EP (1)	EP0006298B1 (de)
JP (1)	JPS554377A (de)
AT (1)	ATE798T1 (de)
AU (1)	AU525094B2 (de)
CA (1)	CA1137978A (de)
DE (1)	DE2962383D1 (de)
DK (1)	DK247479A (de)
IE (1)	IE48337B1 (de)
IL (1)	IL57497A (de)
NZ (1)	NZ190581A (de)
ZA (1)	ZA792622B (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE54220B1 (en) *	1981-12-23	1989-07-19	Ici Plc	Phenol esters
US5331012A (en) *	1990-07-30	1994-07-19	Riddick Kenneth B	Topical pharmaceutical preparation for fever blisters and other viral infections and method of use
GB9212673D0 (en) *	1992-06-15	1992-07-29	Celltech Ltd	Chemical compounds
GB9222253D0 (en) *	1992-10-23	1992-12-09	Celltech Ltd	Chemical compounds
DE69329544T2 (de) *	1992-12-22	2001-05-31	Eli Lilly And Co., Indianapolis	HIV Protease hemmende Verbindungen
US5622977A (en) *	1992-12-23	1997-04-22	Celltech Therapeutics Limited	Tri-substituted (aryl or heteroaryl) derivatives and pharmaceutical compositions containing the same
GB9226830D0 (en) *	1992-12-23	1993-02-17	Celltech Ltd	Chemical compounds
GB9304919D0 (en) *	1993-03-10	1993-04-28	Celltech Ltd	Chemical compounds
GB9304920D0 (en) *	1993-03-10	1993-04-28	Celltech Ltd	Chemical compounds
GB9326173D0 (en) *	1993-12-22	1994-02-23	Celltech Ltd	Chemical compounds and process
EP0738268B1 (de) *	1993-12-22	2004-03-03	Celltech R&D Limited	Trisubstituierte phenyl-derivate, verfahren zu deren herstellung und deren verwendung als phosphodiesterase (typ iv) hemmstoffe
US5786354A (en) *	1994-06-21	1998-07-28	Celltech Therapeutics, Limited	Tri-substituted phenyl derivatives and processes for their preparation
US6245774B1 (en)	1994-06-21	2001-06-12	Celltech Therapeutics Limited	Tri-substituted phenyl or pyridine derivatives
GB9412571D0 (en)	1994-06-22	1994-08-10	Celltech Ltd	Chemical compounds
GB9412573D0 (en) *	1994-06-22	1994-08-10	Celltech Ltd	Chemical compounds
GB9412672D0 (en) *	1994-06-23	1994-08-10	Celltech Ltd	Chemical compounds
GB9523675D0 (en) *	1995-11-20	1996-01-24	Celltech Therapeutics Ltd	Chemical compounds
GB9526243D0 (en) *	1995-12-21	1996-02-21	Celltech Therapeutics Ltd	Chemical compounds
GB9526245D0 (en) *	1995-12-21	1996-02-21	Celltech Therapeutics Ltd	Chemical compounds
GB9526246D0 (en) *	1995-12-21	1996-02-21	Celltech Therapeutics Ltd	Chemical compounds
GB9608435D0 (en) *	1996-04-24	1996-06-26	Celltech Therapeutics Ltd	Chemical compounds
GB9619284D0 (en) *	1996-09-16	1996-10-30	Celltech Therapeutics Ltd	Chemical compounds
GB9622363D0 (en)	1996-10-28	1997-01-08	Celltech Therapeutics Ltd	Chemical compounds
GB9625184D0 (en) *	1996-12-04	1997-01-22	Celltech Therapeutics Ltd	Chemical compounds
AU5330698A (en)	1996-12-23	1998-07-17	Celltech Therapeutics Limited	Fused polycyclic 2-aminopyrimidine derivatives, their preparation and their use as protein tyrosine kinase inhibitors
GB9705361D0 (en)	1997-03-14	1997-04-30	Celltech Therapeutics Ltd	Chemical compounds
GB9713087D0 (en) *	1997-06-20	1997-08-27	Celltech Therapeutics Ltd	Chemical compounds
NO311317B1 (no)	1999-04-30	2001-11-12	Thin Film Electronics Asa	Apparat omfattende elektroniske og/eller optoelektroniske kretser samt fremgangsmåte til å realisere og/eller integrerekretser av denne art i apparatet
GB9914258D0 (en) *	1999-06-18	1999-08-18	Celltech Therapeutics Ltd	Chemical compounds
GB9924862D0 (en)	1999-10-20	1999-12-22	Celltech Therapeutics Ltd	Chemical compounds
IL159120A0 (en) *	2001-05-29	2004-05-12	Schering Ag	Cdk inhibiting pyrimidines, production thereof and their use as medicaments
ES2699912T3 (es) *	2009-02-11	2019-02-13	Xyleco Inc	Procesamiento de biomasa mediante radiación ionizante
CN108913733A (zh)	2012-10-10	2018-11-30	希乐克公司	生物质的处理
PH12018500546A1 (en)	2012-10-10	2019-04-01	Xyleco Inc	Equipment protecting enclosures
NZ743055A (en)	2013-03-08	2020-03-27	Xyleco Inc	Equipment protecting enclosures
CN103588662B (zh) *	2013-11-06	2015-07-01	浙江大学	连续流微反应器中合成倍他米隆的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4034112A (en) *	1973-06-22	1977-07-05	Imperial Chemical Industries Limited	Ethanolamine derivatives having β-adrenergic blocking activity
GB1460593A (en) *	1973-06-22	1977-01-06	Ici Ltd	Ethanolamine derivatives
GB1468156A (en) *	1973-07-19	1977-03-23	Ici Ltd	Phenylethylamine derivatives
US4041074A (en) *	1973-07-19	1977-08-09	Imperial Chemical Industries Limited	1-Hydroxyaryl-2-amidoalkylaminoethanol derivatives
US4041075A (en) *	1973-12-12	1977-08-09	Imperial Chemical Industries Limited	Phenoxy-alkanolamine derivatives
US3928621A (en) *	1974-10-10	1975-12-23	Hoffmann La Roche	Antiinflammatory 2-(2-aminoalkylamino)-1,2-diphenylethanols
US4038417A (en) *	1975-06-19	1977-07-26	Nelson Research & Development Company	Method for treatment of psoriasis
GB1509300A (en) *	1975-12-05	1978-05-04	Ici Ltd	Ethanolamine derivatives
US4154761A (en) *	1976-02-09	1979-05-15	Allen & Hanburys Limited	Pharmacologically active compounds
GB1540463A (en) *	1976-10-07	1979-02-14	Ici Ltd	Alkanolamine derivatives
IE45991B1 (en) *	1976-12-16	1983-01-26	Ici Ltd	Esters of hydroxy amino amides

1979
- 1979-05-21 EP EP79300893A patent/EP0006298B1/de not_active Expired
- 1979-05-21 AT AT79300893T patent/ATE798T1/de not_active IP Right Cessation
- 1979-05-21 DE DE7979300893T patent/DE2962383D1/de not_active Expired
- 1979-05-28 NZ NZ190581A patent/NZ190581A/xx unknown
- 1979-05-28 ZA ZA792622A patent/ZA792622B/xx unknown
- 1979-05-29 US US06/043,425 patent/US4303649A/en not_active Expired - Lifetime
- 1979-05-31 AU AU47652/79A patent/AU525094B2/en not_active Ceased
- 1979-06-06 IL IL57497A patent/IL57497A/xx unknown
- 1979-06-13 CA CA000329655A patent/CA1137978A/en not_active Expired
- 1979-06-14 JP JP7407179A patent/JPS554377A/ja active Pending
- 1979-06-14 DK DK247479A patent/DK247479A/da not_active Application Discontinuation
- 1979-08-08 IE IE1004/79A patent/IE48337B1/en unknown

Also Published As

Publication number	Publication date
ATE798T1 (de)	1982-04-15
JPS554377A (en)	1980-01-12
DE2962383D1 (en)	1982-05-06
DK247479A (da)	1979-12-16
NZ190581A (en)	1981-12-15
AU525094B2 (en)	1982-10-21
US4303649A (en)	1981-12-01
EP0006298A1 (de)	1980-01-09
EP0006298B1 (de)	1982-03-31
IE791004L (en)	1979-12-15
IL57497A0 (en)	1979-10-31
CA1137978A (en)	1982-12-21
AU4765279A (en)	1979-12-20
IE48337B1 (en)	1984-12-12
ZA792622B (en)	1980-02-27

Publication	Publication Date	Title
AU525094B2 (en)	1982-10-21	1-phenyl-2-aminoethanol derivatives
PH16535A (en)	1983-11-10	3,5 substituted phenylbutyl-substituted amino ethanol derivatives,their compositions and their use
MY121032A (en)	2005-12-30	Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof
MY102087A (en)	1992-03-31	Phenethanolamine derivatives.
NO810479L (no)	1981-08-14	Fremgangsmaate for fremstilling av terapeutisk aktive substituerte imidazolderivater
ES8400393A1 (es)	1983-10-16	Un procedimiento para la preparacion de nuevos derivados de ariletanolamina.
FI860107A7 (fi)	1987-07-11	Aminofenolderivat.
HK1047593A1 (zh)	2003-02-28	抗血栓形成的化合物
IE832680L (en)	1984-05-17	Nitrosourea derivatives.
ATE30724T1 (de)	1987-11-15	Cephalosporinderivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen die sie enthalten.
AU578101B2 (en)	1988-10-13	2-thio-imidazolyl derivatives
EP0115920A3 (de)	1986-02-05	Pyrazino(2'3'-3,4)pyrido(1,2-A)-Indolderivate
EP0000644A3 (de)	1979-09-19	Mit niedrigen Cycloalkylresten substituierte Benzolderivate, Verfahren zu ihrer Herstellung, sowie ihre pharmazeutischen Zusammensetzungen